Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2327346284', 'doi': 'https://doi.org/10.4103/0256-4947.71061', 'title': 'K469E polymorphism of the intercellular adhesion molecule-1 gene in Egyptians with coronary heart disease', 'display_name': 'K469E polymorphism of the intercellular adhesion molecule-1 gene in Egyptians with coronary heart disease', 'publication_year': 2010, 'publication_date': '2010-11-01', 'ids': {'openalex': 'https://openalex.org/W2327346284', 'doi': 'https://doi.org/10.4103/0256-4947.71061', 'mag': '2327346284', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20940515', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2994157'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.4103/0256-4947.71061', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S61805644', 'display_name': 'Annals of Saudi Medicine', 'issn_l': '0256-4947', 'issn': ['0256-4947', '0975-4466'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319312', 'host_organization_name': 'King Faisal Specialist Hospital and Research Centre', 'host_organization_lineage': ['https://openalex.org/P4310319312'], 'host_organization_lineage_names': ['King Faisal Specialist Hospital and Research Centre'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2994157?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080558452', 'display_name': 'Amal Ahmed Mohamed', 'orcid': 'https://orcid.org/0000-0002-2014-2239'}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Amal A. Mohamed', 'raw_affiliation_strings': ['From the Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069719894', 'display_name': 'Laila Rashed', 'orcid': 'https://orcid.org/0000-0002-0362-1385'}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Laila Rashed', 'raw_affiliation_strings': ['From the Department of Biochemistry, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Biochemistry, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049338647', 'display_name': 'Hoda M. Amin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Hoda Amin', 'raw_affiliation_strings': ['From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075071512', 'display_name': 'Manal Abu-Farha', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Manal Abu-Farha', 'raw_affiliation_strings': ['From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077640134', 'display_name': 'Soheir Abu El Fadl', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Soheir Abu El Fadl', 'raw_affiliation_strings': ['From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of General Medicine, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5091456705', 'display_name': 'Sameh Pakhoum', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145487455', 'display_name': 'Cairo University', 'ror': 'https://ror.org/03q21mh05', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I145487455']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Sameh Pakhoum', 'raw_affiliation_strings': ['From the Department of Cardiology, Faculty of Medicine, Cairo University, Egypt'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Cardiology, Faculty of Medicine, Cairo University, Egypt', 'institution_ids': ['https://openalex.org/I145487455']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.743, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.780405, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '30', 'issue': '6', 'first_page': '432', 'last_page': '436'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10831', 'display_name': 'Integrin Signaling in Inflammation and Cancer', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10831', 'display_name': 'Integrin Signaling in Inflammation and Cancer', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10292', 'display_name': 'Management of Acute Myocardial Infarction', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10528', 'display_name': 'Inflammation and Obesity-Related Metabolic Disorders', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-adhesion', 'display_name': 'Cell Adhesion', 'score': 0.5377}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.67469776}, {'id': 'https://openalex.org/C3018906752', 'wikidata': 'https://www.wikidata.org/wiki/Q844935', 'display_name': 'Coronary heart disease', 'level': 2, 'score': 0.55250525}, {'id': 'https://openalex.org/C2909375385', 'wikidata': 'https://www.wikidata.org/wiki/Q187637', 'display_name': 'Intercellular Adhesion Molecule-1', 'level': 3, 'score': 0.504161}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.43499565}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.43428862}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.4103/0256-4947.71061', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S61805644', 'display_name': 'Annals of Saudi Medicine', 'issn_l': '0256-4947', 'issn': ['0256-4947', '0975-4466'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319312', 'host_organization_name': 'King Faisal Specialist Hospital and Research Centre', 'host_organization_lineage': ['https://openalex.org/P4310319312'], 'host_organization_lineage_names': ['King Faisal Specialist Hospital and Research Centre'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2994157', 'pdf_url': 'https://europepmc.org/articles/pmc2994157?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994157', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2994157', 'pdf_url': 'https://europepmc.org/articles/pmc2994157?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.62, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 19, 'referenced_works': ['https://openalex.org/W1530281430', 'https://openalex.org/W1671590615', 'https://openalex.org/W1979182356', 'https://openalex.org/W1982803556', 'https://openalex.org/W2000097001', 'https://openalex.org/W2015155921', 'https://openalex.org/W2030368761', 'https://openalex.org/W2058610272', 'https://openalex.org/W2113012623', 'https://openalex.org/W2117521530', 'https://openalex.org/W2118675478', 'https://openalex.org/W2132399471', 'https://openalex.org/W2133012189', 'https://openalex.org/W2186431788', 'https://openalex.org/W2372329813', 'https://openalex.org/W2415914193', 'https://openalex.org/W2432767515', 'https://openalex.org/W2444546517', 'https://openalex.org/W4239192793'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': {'original': [0, 3166], 'articleK469E': [1], 'polymorphism': [2, 210, 275, 283, 393, 415, 668, 890, 913, 1721, 1925, 1983, 2361, 2382, 2588, 2683, 2724, 2844], 'of': [3, 37, 43, 61, 64, 82, 86, 104, 108, 128, 132, 151, 154, 189, 208, 211, 259, 299, 320, 429, 445, 462, 473, 509, 521, 525, 551, 570, 581, 594, 602, 658, 666, 669, 690, 728, 735, 750, 807, 830, 888, 891, 943, 947, 957, 972, 977, 983, 1007, 1060, 1070, 1082, 1094, 1117, 1125, 1132, 1226, 1266, 1304, 1336, 1407, 1411, 1463, 1473, 1491, 1610, 1624, 1638, 1679, 1689, 1704, 1743, 1746, 1768, 1785, 1900, 1910, 1963, 1984, 2009, 2022, 2034, 2129, 2140, 2160, 2176, 2197, 2204, 2255, 2302, 2312, 2339, 2357, 2420, 2428, 2438, 2490, 2527, 2589, 2725, 2771, 2779, 2857, 2902, 2944, 2949, 2987, 3022, 3030, 3093, 3102, 3137, 3148], 'the': [4, 35, 59, 80, 102, 126, 149, 187, 206, 212, 273, 277, 297, 426, 432, 446, 510, 519, 528, 549, 637, 664, 670, 726, 740, 780, 863, 898, 907, 928, 1043, 1061, 1067, 1071, 1079, 1083, 1095, 1136, 1142, 1166, 1171, 1207, 1293, 1360, 1408, 1464, 1474, 1505, 1538, 1605, 1611, 1622, 1636, 1658, 1669, 1702, 1726, 1741, 1776, 1836, 1843, 1901, 1912, 1922, 1968, 1981, 1985, 2002, 2023, 2029, 2032, 2035, 2126, 2133, 2145, 2156, 2161, 2164, 2172, 2177, 2243, 2269, 2299, 2309, 2330, 2337, 2352, 2358, 2368, 2426, 2439, 2590, 2903, 2947, 3068, 3146, 3149, 3165], 'intercellular': [5, 197, 484, 2422, 2455, 2491, 2591, 2838], 'adhesion': [6, 188, 198, 485, 498, 511, 530, 550, 560, 1618, 2423, 2456, 2492, 2530, 2592, 2637, 2807, 2839, 2983, 3024], 'molecule-1': [7, 199, 499, 561, 1619, 2424, 2457, 2493, 2593, 2638, 2840], 'gene': [8, 214, 392, 609, 672, 1413, 1720, 1889, 1987, 2360, 2494, 2594, 2681, 2727, 2775, 2842], 'in': [9, 184, 226, 333, 373, 394, 405, 421, 431, 471, 518, 541, 546, 583, 625, 636, 640, 682, 739, 763, 869, 952, 1115, 1275, 1292, 1351, 1359, 1383, 1395, 1414, 1563, 1615, 1635, 1657, 1661, 1708, 1722, 1725, 1789, 1805, 1809, 1835, 1870, 1882, 1907, 1928, 1967, 1993, 2041, 2079, 2093, 2125, 2150, 2163, 2174, 2236, 2247, 2257, 2278, 2290, 2305, 2362, 2373, 2388, 2500, 2533, 2647, 2732, 2777, 2781, 2806, 2879, 2916, 2946, 2952, 3026, 3067, 3097, 3161], 'Egyptians': [10], 'with': [11, 221, 239, 244, 251, 263, 316, 335, 345, 378, 384, 399, 493, 677, 693, 699, 707, 774, 794, 994, 1042, 1285, 1298, 1353, 1385, 1397, 1466, 1480, 1568, 1628, 1686, 1701, 1711, 1823, 1850, 1862, 1991, 1995, 2026, 2098, 2108, 2132, 2224, 2261, 2288, 2336, 2367, 2641, 2734, 2848, 2913, 2918, 3099], 'coronary': [12, 222, 678, 769, 1305, 1639, 1771, 2109, 2209, 2390, 2498, 2602, 2685, 2735, 2880, 2988, 3031, 3103], 'heart': [13, 223, 679, 1306, 1852, 2391, 2603, 2686, 2736, 2850, 2989], 'disease': [14, 224, 321, 423, 680, 1307, 1690, 2110, 2211, 2275, 2604, 2643, 2882, 2951], 'Amal': [15, 31], 'A.': [16, 32], 'Mohamed,': [17], 'Laila': [18, 56], 'Rashed,': [19], 'Hoda': [20, 77], 'Amin,': [21], 'Manal': [22, 99], 'Abu-Farha,': [23], 'Soheir': [24, 121], 'Abu': [25, 122], 'El': [26, 123], 'Fadl,': [27], 'and': [28, 39, 145, 215, 249, 303, 313, 357, 361, 364, 416, 438, 475, 488, 527, 533, 572, 654, 673, 704, 718, 731, 768, 789, 820, 835, 927, 980, 1026, 1076, 1089, 1119, 1127, 1145, 1170, 1202, 1234, 1243, 1253, 1277, 1282, 1287, 1311, 1338, 1348, 1369, 1380, 1387, 1392, 1425, 1470, 1484, 1529, 1551, 1581, 1597, 1630, 1674, 1683, 1730, 1773, 1791, 1811, 1839, 1845, 1926, 1944, 1950, 1961, 1965, 2039, 2065, 2085, 2089, 2120, 2213, 2273, 2281, 2319, 2343, 2354, 2383, 2399, 2495, 2605, 2645, 2684, 2728, 2773, 2883, 2941, 2985, 2994, 3061, 3064, 3159], 'Sameh': [29, 146], 'Pakhoum': [30, 147], 'Mohamed': [33], 'From': [34, 58, 79, 101, 125, 148], 'Department': [36, 60, 81, 103, 127, 150, 727], 'Clinical': [38], 'Chemical': [40], 'Pathology,': [41], 'Faculty': [42, 63, 85, 107, 131, 153], 'Medicine,': [44, 65, 84, 87, 106, 109, 130, 133, 155], 'Cairo': [45, 66, 88, 110, 134, 156, 736], 'University,': [46, 67, 89, 111, 135, 157], 'Egypt': [47, 68, 90, 112, 136, 158], 'Search': [48, 69, 91, 113, 137, 159], 'for': [49, 70, 92, 114, 138, 160, 272, 402, 450, 467, 592, 1000, 1009, 1015, 1021, 1033, 1052, 1149, 1206, 1217, 1498, 1504, 1718, 1728, 1754, 2370, 2601], 'more': [50, 71, 93, 115, 139, 161, 1290, 1818], 'papers': [51, 72, 94, 116, 140, 162], 'by': [52, 73, 95, 117, 141, 163, 196, 276, 290, 413, 558, 848, 873, 881, 1004, 1100, 1108, 1164, 1855, 2113, 2380], 'this': [53, 74, 96, 118, 142, 164, 414, 659, 2334, 2381], 'author': [54, 75, 97, 119, 143, 165], ',': [55, 76, 98, 120, 144, 2482, 2485, 2581, 2584, 2629, 2632, 2671, 2674, 2714, 2717, 2764, 2767, 2831, 2834, 2976, 2979, 3015, 3018, 3054, 3057], 'Rashed': [57], 'Biochemistry,': [62], 'Amin': [78], 'General': [83, 105, 129], 'Abu-Farha': [100], 'Fadl': [124], 'Cardiology,': [152], 'Published': [166], 'Online:2': [167], 'Dec': [168], '2010https://doi.org/10.4103/0256-4947.71061SectionsPDF': [169], 'ToolsAdd': [170], 'to': [171, 191, 204, 310, 327, 343, 442, 457, 553, 576, 598, 619, 633, 648, 651, 662, 745, 809, 1461, 1468, 1604, 1654, 1696, 1872, 1884, 1894, 2007, 2052, 2155, 2242, 2298, 2432], 'favoritesDownload': [172], 'citationTrack': [173], 'citations': [174], 'ShareShare': [175], 'onFacebookTwitterLinked': [176], 'InRedditEmail': [177], 'AboutAbstractBACKGROUND': [178], 'AND': [179, 229, 685], 'OBJECTIVES:': [180], 'The': [181, 255, 543, 588, 607, 656, 748, 857, 916, 1036, 1057, 1092, 1262, 1372, 1999, 3070], 'initial': [182, 544, 996], 'step': [183, 545, 999, 1030], 'atherosclerosis': [185, 547, 2429], 'is': [186, 397, 410, 417, 501, 507, 548, 566, 596, 610, 1608, 2377, 2384, 2639, 2804, 2845, 3140, 3168], 'leukocytes': [190, 522, 532, 552, 1629], 'activated': [192, 554, 1625], 'endothelial': [193, 555, 586, 1626, 1867], 'cells': [194, 556, 1627], 'mediated': [195, 557], '(ICAM-1).': [200], 'This': [201, 1699, 1898, 2148, 2293], 'study': [202, 660, 687, 1137, 1220, 1854, 1978, 2166, 2251, 2307, 2721, 2993], 'aimed': [203], 'investigate': [205, 663], 'association': [207, 665, 1920], 'K469E': [209, 667, 889, 1409, 1924, 1959, 1982, 2061, 2489, 2682, 2723, 2843, 2900], 'ICAM-1': [213, 217, 274, 391, 564, 571, 582, 603, 608, 671, 867, 892, 1412, 1641, 1659, 1672, 1719, 1747, 1777, 1863, 1888, 1923, 1986, 2060, 2359, 2680, 2772], 'soluble': [216, 483, 2421, 3023, 3094], '(sICAM-1)': [218, 565], 'serum': [219, 675, 764, 831, 870, 1516], 'level': [220, 676, 859, 1328, 2104, 2139, 2731], '(CHD)': [225, 681, 1308], 'Egyptian': [227, 406, 683, 1821, 2782], 'subjects.PATIENTS': [228, 684], 'METHODS:': [230], 'Using': [231], 'a': [232, 400, 459, 515, 538, 567, 805, 944, 1027, 1103, 1487, 1632, 1765, 1783, 1832, 1904, 1929, 1976, 2069, 2184, 2195], 'case-control': [233], 'design,': [234], 'we': [235], 'studied': [236, 1969, 2268], '100': [237, 691, 975, 1222], 'patients': [238, 243, 334, 344, 356, 366, 377, 692, 698, 706, 1245, 1281, 1309, 1352, 1384, 1396, 1500, 1524, 1567, 1682, 1710, 1807, 1822, 1943, 2044, 2054, 2084, 2097, 2107, 2162, 2173, 2304, 2318, 2733, 3098], 'CHD,': [240, 695, 1354, 1712], 'including': [241, 696], '73': [242, 697, 1244], 'acute': [245, 694, 700, 1247, 2042, 2169, 2225, 2229, 2320, 2389], 'myocardial': [246, 701, 1248, 1421, 1816, 2230, 2606, 2884], 'infarction': [247, 702, 1249, 1422, 1817], '(MI)': [248, 703, 1250, 1423], '27': [250, 705, 1225], 'unstable': [252, 708, 1229, 1417], 'angina': [253, 709, 1230, 1418], '(UA).': [254], 'control': [256, 781, 1263, 1361, 1530, 2086], 'group': [257, 782, 1264, 1295, 2067], 'consisted': [258, 689, 1265], '50': [260, 1267], 'healthy': [261, 772, 1268], 'subjects': [262, 773, 814, 1531, 1994, 2087], 'normal': [264, 775, 1866], 'left': [265, 776], 'ventricular': [266, 777], 'function.': [267], 'All': [268, 1186], 'participants': [269], 'were': [270, 305, 314, 352, 369, 723, 798, 802, 823, 846, 871, 1074, 1086, 1098, 1112, 1189, 1271, 1289, 1343, 1364, 1375, 1543, 1559, 1684, 2075, 2202], 'genotyped': [271], 'polymerase': [278, 908, 986], 'chain': [279, 909], 'reaction-restriction': [280, 910], 'fragment': [281, 911, 946, 1058, 1068, 1080], 'length': [282, 912, 1059], '(PCR-RFLP)': [284, 914], 'method.': [285, 915], 'Serum': [286, 349, 408, 819], 'sICAM-1': [287, 350, 374, 386, 409, 595, 674, 1541, 1564, 2080, 2094, 2103, 2141, 2200, 2234, 2256, 2285, 2376], 'was': [288, 661, 752, 837, 860, 895, 904, 919, 931, 950, 991, 1039, 1064, 1139, 1158, 1162, 1182, 1591, 1803, 1954, 1988, 2111, 2286, 2324], 'measured': [289, 872], 'enzyme-linked': [291, 876], 'immunoassay': [292, 877], '(ELISA).RESULTS:': [293], 'In': [294, 1537, 1732, 1820, 2071, 2183, 2314], 'CHD': [295, 355, 403, 751, 1223, 1280, 1294, 1415, 1492, 1499, 1523, 1539, 1681, 1729, 1806, 1927, 1942, 1964, 2066, 2083, 2262, 2371], 'patients,': [296, 1224, 2322], 'frequencies': [298, 332, 1123, 1129, 1342, 1374, 2033], 'K': [300, 330, 1475, 1481, 1507, 1800, 1812, 2036, 2134, 2146], 'genotype': [301, 331, 1063, 1073, 1085, 1339, 1341, 1373, 1465, 1745, 1779, 1949, 2037], '(KK': [302, 1483, 2038], 'EK)': [304, 1485, 2040], 'significantly': [306, 1488], 'higher': [307, 385, 1766, 1804, 2137, 2253], 'when': [308, 341, 1296], 'compared': [309, 342, 1297, 1460, 2051, 2059, 2431], 'controls': [311, 358, 1299, 1312, 1426, 1945], '(P<.001)': [312], 'associated': [315, 398, 492, 1685, 1990, 2223, 2287, 2366, 2640, 2847], 'an': [317, 502, 626, 995, 1647, 1715, 1751, 2168, 3141], 'increased': [318, 494, 1458, 1489, 1687, 1752], 'risk': [319, 401, 466, 1490, 1688, 1753, 1767, 2276, 2369, 2599, 2644, 3066], 'development': [322, 404, 2372], '(OR=3.8,': [323], '95%': [324, 1172], 'CI:': [325, 1694], '1.7': [326, 1695], '8.5;': [328, 1697], 'P=.001).': [329, 1698], 'MI': [336, 363, 1386, 1546, 1966, 1992, 2043, 2064, 2321], 'showed': [337, 1477, 1518, 1859, 2046, 2252], 'no': [338, 370, 1272, 1400, 1519, 1560, 1919, 1938, 1955, 2047, 2076, 2090, 2325], 'significant': [339, 371, 1273, 1401, 1520, 1561, 1589, 1939, 2048, 2077, 2091, 2326], 'difference': [340, 1402, 1521, 1590, 1834, 2049, 2149, 2294, 2327], 'UA': [346, 365, 1552, 2053, 2317], '(P=': [347, 359], '.121).': [348], 'levels': [351, 375, 387, 868, 1517, 1542, 1565, 2081, 2095, 2201, 2235, 2254, 2332, 2526], 'comparable': [353, 1544], 'between': [354, 362, 531, 1135, 1279, 1522, 1545, 1566, 1593, 1842, 1921, 1941, 1958, 2063, 2082, 2233, 2271, 2316, 2679], '.37)': [360], '(P=.23).': [367, 1557], 'There': [368, 1270, 1558], 'differences': [372, 1274, 1562, 1940, 2078, 2092, 2246], 'among': [376, 1848, 2001, 2096, 2106, 2192], 'different': [379, 1569, 2013, 2020, 2099, 2237, 2310, 3100], 'genotypes': [380, 2100, 2356], '(P=.532).': [381, 1587], 'Men': [382], 'presented': [383], 'than': [388, 1180, 1808, 2142, 2259], 'women': [389, 1598, 2193, 2260, 2291], '(P=.004).CONCLUSION:': [390], 'codon': [395, 643, 1664, 1723, 1748, 2363, 2597], '469': [396, 1724, 1749, 2364], 'subjects.': [407, 1269], 'not': [411, 418, 1989, 2220, 2378, 2385, 2846], 'influenced': [412, 2379], 'necessarily': [419, 2386], 'elevated': [420, 2387], 'CHD.IntroductionCardiovascular': [422], '(CVD)': [424, 2277], 'remains': [425], 'leading': [427], 'cause': [428], 'death': [430], 'developed': [433], 'world.': [434], 'Although': [435], 'hyperlipidemia': [436], 'screening': [437], 'treatment': [439], 'has': [440, 573, 645, 1666], 'proven': [441], 'be': [443, 599, 649, 1892, 2005, 2153, 2240, 2296], 'one': [444, 508, 1609], 'most': [447, 2159], 'effective': [448], 'tools': [449], 'reducing': [451], 'CVD': [452, 495, 2289], 'burden,': [453], 'it': [454, 506], 'often': [455], 'fails': [456], 'identify': [458], 'substantial': [460], 'proportion': [461], 'persons': [463], 'at': [464, 523, 825, 1012, 1018, 1024, 1031, 1055], 'high': [465, 479], 'CVD-associated': [468], 'events.': [469], 'Elevations': [470], 'markers': [472, 2943], 'inflammation': [474, 526, 2272, 2945], 'thrombosis,': [476], 'such': [477], 'as': [478, 1459, 1782, 1946, 2050, 2068, 2216, 2228, 2328, 2430], 'sensitivity': [480], 'C-reactive': [481], 'protein,': [482], 'molecule,': [486], 'homocysteine': [487], 'fibrinogen,': [489], 'are': [490, 1332, 2365], 'also': [491], 'risk.1': [496], 'Intercellular': [497, 1617], '(ICAM-1)': [500, 1620, 2841, 2908], 'important': [503, 1716], 'inflammatory': [504, 652, 796], 'protein;': [505], 'molecules': [512, 2984, 3025, 3096], 'that': [513, 1478, 1740, 1761, 1775, 1799, 1860, 1887, 1952, 1980, 2158, 2191, 2207, 2284, 2351], 'plays': [514, 537, 1631, 1903], 'key': [516, 1905], 'role': [517, 540, 1634, 1717, 1906], 'recruitment': [520], 'sites': [524], 'tight': [529], 'vascular': [534, 585, 1606, 2802], 'endothelium.': [535], 'Inflammation': [536], 'critical': [539, 732], 'atherogenesis.': [542], 'intracellular': [559, 2636], '(ICAM-1).2': [562], 'Soluble': [563, 866], 'circulating': [568, 2528], 'form': [569], 'been': [574, 646, 1667], 'shown': [575], 'reflect': [577, 2208], 'cell': [578, 605], 'surface': [579], 'expression': [580], 'human': [584, 2534], 'cells.': [587], 'main': [589], 'mechanism': [590], 'responsible': [591], 'release': [593], 'believed': [597], 'proteolytic': [600], 'cleavage': [601], 'from': [604, 630, 725, 742, 812, 1357, 1651, 1971, 2012], 'membranes.3': [606], 'located': [611], 'on': [612, 754, 839, 1102, 2425, 2722], 'chromosome': [613], '19': [614], 'p13.2-p13.3.': [615], 'A': [616, 1176, 1588, 2435, 2553, 2991], 'single-base': [617, 1642], 'C': [618, 2830], 'T': [620], 'transition': [621], 'polymorphism,': [622, 1644], 'which': [623, 1363, 1645, 3154], 'results': [624, 2151, 2349], 'amino': [627, 1648], 'acid': [628, 1649], 'substitution': [629, 1650], 'glutamine': [631, 1652], '(E)': [632, 1653], 'lysine': [634, 1655], '(K)': [635, 1656], 'ICAM': [638], 'protein': [639, 1660, 2940], 'exon': [641, 948, 1662], '6': [642, 949, 1663], '469,': [644, 1665], 'found': [647, 1592, 1739, 1798, 1831, 1918, 1937, 2190, 2283], 'related': [650, 1893], 'diseases': [653], 'atherosclerosis.4': [655], 'aim': [657], 'METHODSThe': [686], 'population': [688, 1970, 2128], '(UA)': [710, 1231, 1419], '(mean': [711, 783, 1525, 1532, 1547, 1553, 1572, 1577, 1583], '[standard': [712], 'deviation]': [713], 'age:': [714, 785], '52.6': [715], '[8.29]': [716], 'years;': [717], 'male/female': [719, 790], 'ratio:': [720, 791], '87/13).': [721], 'They': [722], 'recruited': [724], 'Internal': [729], 'Medicine': [730], 'care': [733], 'unit': [734], 'University': [737], 'Hospitals': [738], 'period': [741], 'October': [743], '2008': [744], 'June': [746, 3128], '2009.': [747], 'diagnosis': [749], 'based': [753], 'medical': [755], 'history,': [756], 'physical': [757], 'examination,': [758], 'typical': [759], 'electrocardiographic': [760], 'changes,': [761], 'increases': [762], 'cardiac': [765], 'enzymes': [766], 'activities': [767], 'angiography.': [770], 'Fifty': [771], 'function': [778, 1868, 1890], 'constituted': [779], '[SD]': [784, 1238, 1257], '53.9': [786], '[6.2]': [787], 'years,': [788], '38/12).': [792], 'Subjects': [793], 'any': [795, 3162], 'condition': [797], 'excluded.': [799], 'Blood': [800], 'samples': [801, 822], 'collected': [803], 'after': [804, 815, 1770, 1874, 2497], 'fast': [806], '12': [808, 1053], '14': [810], 'hours': [811, 1054], 'all': [813, 1908], 'obtaining': [816], 'oral': [817], 'consent.': [818], 'EDTA': [821], 'stored': [824], '–20°C': [826], 'until': [827], 'assay': [828], 'time.Assay': [829], 'total': [832], 'cholesterol,': [833], 'HDL': [834], 'triglycerides': [836], 'performed': [838, 896, 905, 951, 1163], 'automated': [840], 'analyzer,': [841], 'Hitachi': [842], '917;': [843], 'commercial': [844], 'kits': [845], 'supplied': [847, 880], 'Roche': [849], 'Diagnostics': [850], '(Boehringer': [851], 'Mannheim,': [852, 855], 'GmbH': [853], 'D-68298,': [854], 'Germany).': [856], 'LDL': [858], 'calculated': [861], 'using': [862, 897, 906, 1141, 1191, 2854], 'Friedwald': [864], 'equation.': [865], 'solid-phase': [874], 'sandwich': [875], '(ELISA)': [878], 'kit': [879], 'Thermo': [882], 'Scientific': [883], 'Life': [884], 'Science,': [885], 'USA.5Molecular': [886], 'analysis': [887, 903, 1161, 2437], 'geneDNA': [893], 'extraction': [894], 'standard': [899, 1120], 'salting-out': [900], 'technique.6': [901], 'Genotype': [902, 1429], 'sense': [917], 'primer': [918, 930], '5’-GGA': [920], 'ACC': [921], 'CAT': [922], 'TGC': [923, 936], 'CCG': [924], 'AGC': [925], '-3’,': [926], 'antisense': [929], '5’-': [932], 'GGT': [933], 'GAG': [934], 'GAT': [935], 'ATT': [937], 'AGG': [938], 'TC': [939], '-3’.': [940], 'PCR': [941, 1037], 'amplification': [942], '223-bp': [945], '50-μL': [953], 'reaction': [954], 'mixture': [955], 'consisting': [956], '67': [958], 'mM': [959, 964, 968], 'Tris-HCl': [960], '(pH,': [961], '8.8),': [962], '1': [963, 1010, 1016, 1022, 1302, 2532, 2907], 'magnesium': [965], 'chloride,': [966], '10': [967, 1001, 1034], 'dNTPs,': [969], '5': [970, 1235], 'pmol': [971], 'each': [973], 'primer,': [974], 'ng': [976], 'extracted': [978], 'DNA': [979, 985], '2.5': [981], 'units': [982], 'Taq': [984], '(Amersham': [987, 1048], 'Pharmacia': [988, 1049], 'Biotech.).Thermal': [989], 'cycling': [990], 'carried': [992], 'out': [993], '95°C': [997], 'denaturation': [998, 1008], 'minutes,': [1002], 'followed': [1003, 1107], '35': [1005], 'cycles': [1006], 'minute': [1011, 1017, 1023], '95°C,': [1013], 'annealing': [1014], '58°C,': [1019], 'extension': [1020, 1029], '72°C': [1025, 1032], 'final': [1028], 'minutes.': [1035], 'product': [1038], 'then': [1040], 'digested': [1041], 'restriction': [1044], 'enzyme': [1045], 'BstU': [1046], 'I': [1047], 'Biotech.,': [1050], 'USA)': [1051, 1201, 1214], '37°C.': [1056], 'KK': [1062, 1350, 1382, 1394, 1582, 1675, 1744, 1762, 1778, 1948, 2353], '223': [1065], 'bp;': [1066, 1078], 'lengths': [1069, 1081], 'EE': [1072, 1571, 1844], '136': [1075, 1088], '87': [1077, 1090], 'EK': [1084, 1347, 1368, 1379, 1391, 1576, 1673, 1846, 2355], '223,': [1087], 'bp.': [1091], 'products': [1093], 'digestion': [1096], 'process': [1097], 'separated': [1099], 'electrophoresis': [1101], '2.5%': [1104], 'agarose': [1105], 'gel,': [1106], 'ethidium': [1109], 'bromide': [1110], 'staining.4Data': [1111], 'statistically': [1113, 1184], 'described': [1114], 'terms': [1116, 3147], 'mean': [1118, 1237, 1256, 1333], 'deviation': [1121], '(SD),': [1122], '(number': [1124], 'cases)': [1126], 'relative': [1128], '(percentages).': [1130], 'Comparison': [1131], 'quantitative': [1133], 'variables': [1134], 'groups': [1138, 2011], 'done': [1140, 1190], 't': [1143], 'test': [1144, 1148, 1157], 'one-way': [1146], 'ANOVA': [1147], 'independent': [1150], 'samples.': [1151], 'For': [1152], 'comparing': [1153], 'categorical': [1154], 'data,': [1155], 'chi-square': [1156], 'performed.': [1159], 'Risk': [1160, 2787], 'calculating': [1165], 'odds': [1167], 'ratio': [1168, 1509], '(OR)': [1169], 'confidence': [1173], 'interval': [1174], '(CI).': [1175], 'P': [1177], 'value': [1178], 'less': [1179], '.05': [1181], 'considered': [1183], 'significant.': [1185], 'statistical': [1187, 1833], 'calculations': [1188], 'computer': [1192], 'programs': [1193], 'Microsoft': [1194, 1218], 'Excel': [1195], 'version': [1196, 1215], '7': [1197], '(Microsoft': [1198], 'Corporation,': [1199], 'NY,': [1200], 'SPSS': [1203, 1210], '(Statistical': [1204], 'Package': [1205], 'Social': [1208], 'Science;': [1209], 'Inc.,': [1211], 'Chicago,': [1212], 'IL,': [1213], '15': [1216], 'Windows.RESULTSThis': [1219], 'included': [1221], 'whom': [1227], 'had': [1228, 1246, 1486, 1764, 1865, 1879, 2136, 2167, 2180], '(22': [1232], 'men': [1233, 1252, 1594, 2258], 'women,': [1236, 1255], 'age,': [1239, 1258], '54.9': [1240], '[8.7]': [1241], 'years),': [1242], '(65': [1251], '8': [1254], '50.3': [1259], '[7.9]': [1260], 'years).': [1261], 'age': [1276], 'gender': [1278], 'controls.': [1283], 'Patients': [1284], 'hypercholesterolemia': [1286], 'smokers': [1288], 'frequent': [1291], '(Table': [1300, 1403, 1493], '1).Table': [1301], 'Characteristics': [1303], '(n=100)': [1310], '(n=': [1313, 1427], '50).VariableCHD': [1314], 'patientsControlsPAge': [1315], '(years)a52.6': [1316], '(8.29)53.9': [1317], '(6.2).34Gender': [1318], '(male': [1319], '/female)87': [1320], '/1338': [1321], '/12.23Hypertension': [1322], '(%)7168.70Smoking': [1323], '(%)6539.002Diabetes': [1324], 'mellitus': [1325], '(%)3026.61Hypercholesterolemia': [1326], '(%)7952.001ICAM': [1327], '(pg/mL)a838.79': [1329], '(153.93)802.55': [1330], '(144.68).37aValues': [1331], '(standard': [1334], 'deviation).Distribution': [1335], 'allele': [1337, 1447, 1476, 1482, 1801, 1813, 2135], 'frequenciesThe': [1340], '43%': [1344], 'EE,': [1345, 1366, 1377, 1389], '37%': [1346], '20%': [1349], 'thus': [1355], 'differing': [1356], 'those': [1358, 1849, 2143, 2221], 'subjects,': [1362], '74%': [1365], '22%': [1367], '4%': [1370], 'KK.': [1371], '38.3%': [1376, 1378], '23.3%': [1381], '55.6%': [1388], '33.3%': [1390], '11.1%': [1393], 'UA,': [1398], 'showing': [1399], '2).Table': [1404], '2': [1405, 1997, 2920], 'Frequencies': [1406], 'variants': [1410, 1676, 1847], '(n=100),': [1416], '(n=27),': [1420], '(n=73)': [1424], '50).CHDUAMIControlsICAM-1': [1428], 'n': [1430, 1448], '(%)EE43': [1431], '(43)15': [1432], '(55.6)28': [1433], '(38.33)37': [1434], '(74)EK37': [1435], '(37)a9': [1436], '(33.3)a28': [1437], '(38.33)a11': [1438], '(22)KK20': [1439], '(20)a3': [1440], '(11.1)a17': [1441], '(23.3)a2': [1442], '(4.0)KK+EK57(57)a12': [1443], '(44.4)a45': [1444], '(61.65)a13': [1445], '(26.0)ICAM-1': [1446], '(%)E123': [1449], '(61.5)39': [1450], '(72.2)84': [1451], '(57.5)85': [1452], '(85)K77': [1453], '(38.5)a15': [1454], '(27.8)a62': [1455], '(42.5)a15': [1456], '(15)aSignificantly': [1457], 'controls.Analysis': [1462], 'respect': [1467], 'dominant': [1469], 'additive': [1471], 'effects': [1472], 'individuals': [1479, 2131], '3).Table': [1494], '3': [1495], 'Odds': [1496], 'ratios': [1497], 'heterozygous': [1501], 'or': [1502, 2019, 2308], 'homozygous': [1503], '-469': [1506], 'variant.GenotypeOdds': [1508], '(95%': [1510, 1693], 'CI)PEK2.9': [1511], '(1.2-7.8).014KK8.6': [1512], '(1.8-57.2).003KK+EK3.8': [1513], '(1.7-8.5).001Serum': [1514], 'sICAM-1sICAM-1': [1515], '[SD],': [1526, 1533, 1548, 1554, 1573, 1578, 1584], '838.79': [1527], '(153.93)pg/mL)': [1528], '802.55': [1534], '(144.68)pg/mL)': [1535], '(P=.37).': [1536], 'group,': [1540], '828.17': [1549], '(158.72)pg/mL)': [1550], '867.52': [1555], '(138.87)pg/mL)': [1556], 'genotypes;': [1570], '809.51': [1574], '(132.8)pg/mL),': [1575], '816.21': [1579], '(116.82)pg/mL)': [1580], '847.23': [1585], '(125.7)pg/mL)': [1586], '(854.966': [1595], '(153.33)pg/mL)': [1596], '(720.183': [1599], '(99.36)': [1600], 'pg/mL)': [1601], '(P=.004).DISCUSSIONLeukocyte': [1602], 'adherence': [1603], 'endothelium': [1607, 1902], 'earliest': [1612], 'demonstrable': [1613], 'events': [1614, 2206, 2222], 'atherosclerosis.7': [1616], 'mediates': [1621], 'interaction': [1623], 'fundamental': [1633], 'pathogenesis': [1637, 2778], 'atherosclerosis.': [1640], 'C/T': [1643], 'determines': [1646], 'described.8In': [1668], 'current': [1670, 2165], 'study,': [1671, 2031, 2186], 'represented': [1677], '57%': [1678], 'our': [1680, 2072, 2306, 2348], 'development;': [1691], 'OR=3.8': [1692], 'agrees': [1700, 2335], 'findings': [1703, 2338], 'Jiang': [1705, 2569], 'et': [1706, 1737, 1758, 1796, 1829, 1857, 1916, 1935, 2115, 2118, 2122, 2188, 2266, 2341, 2345, 2483, 2486, 2582, 2585, 2630, 2633, 2672, 2675, 2715, 2718, 2765, 2768, 2832, 2835, 2977, 2980, 3016, 3019, 3055, 3058], 'al': [1707], 'German': [1709], 'who': [1713], 'suggested': [1714], 'susceptibility': [1727], 'MI.': [1731], 'Han': [1733, 2127], 'Chinese': [1734, 2501], 'population,': [1735], 'Zhang': [1736, 2476, 2659, 2665], 'al9': [1738], 'presence': [1742], 'conferred': [1750], 'CHD.': [1755, 2182], 'Also,': [1756, 1975, 2124], 'Liu': [1757, 2470], 'al4': [1759], 'reported': [1760, 1979, 2112], 'homozygotes': [1763], 're-stenosis': [1769], 'stenting': [1772, 2499], 'concluded': [1774, 1951], 'may': [1780, 1891, 2152, 2295], 'serve': [1781], 'predictor': [1784], 'in-stent': [1786], 're-stenosis,': [1787], 'especially': [1788], 'obese': [1790], 'hyperlipemia': [1792], 'patients.': [1793, 2313], 'Similarly,': [1794, 1933], 'Lu': [1795, 2702], 'al10': [1797], 'frequency': [1802], 'controls,': [1810], 'carriers': [1814], 'develop': [1815], 'easily.': [1819], 'peripheral': [1824], 'arterial': [1825, 2433], 'occlusive': [1826], 'disease,': [1827, 2199], 'Shaker': [1828, 2752], 'al11': [1830], 'clinical': [1837, 3028], 'history': [1838, 2196], 'laboratory': [1840, 2554], 'data': [1841], 'ischemic': [1851], 'disease.A': [1853], 'Banda': [1856, 2794], 'al12': [1858], 'mice': [1861, 1878], 'deficiency': [1864], '(vasorelaxation': [1869], 'response': [1871, 1883], 'acetylcholine)': [1873], 'ischemia-reperfusion,': [1875], 'whereas': [1876], 'wild-type': [1877], 'impaired': [1880, 1895], 'vasorelaxation': [1881], 'acetylcholine,': [1885], 'indicating': [1886], 'endothelium-dependent': [1896, 2801], 'vasodilatation.': [1897], 'dysfunction': [1899], 'stages': [1909], 'atherosclerosis.On': [1911], 'other': [1913, 2942], 'hand,': [1914], 'McGlinchey': [1915, 2819], 'al13': [1917], 'well-defined': [1930], 'Irish': [1931], 'population.': [1932], 'Aminian': [1934, 2868], 'al14': [1936], 'regards': [1947, 2329], 'there': [1953, 2074, 2323], 'strong': [1956], 'relation': [1957, 2270], 'polymorphisms': [1960, 2062, 2776, 2876], 'occurrence': [1962], 'Fars': [1972], 'province,': [1973], 'Iran.': [1974], 'Slovenian': [1977], 'type': [1996], 'diabetes.15': [1998], 'discrepancy': [2000], 'studies': [2003, 2058, 2179, 2238], 'could': [2004], 'due': [2006, 2154], 'selection': [2008], 'patient': [2010], 'ethnic': [2014, 2245], 'populations,': [2015], 'variable': [2016], 'sample': [2017], 'sizes': [2018], 'interactions': [2021], 'genetic': [2024], 'background': [2025], 'environmental': [2027], 'factors.In': [2028], 'present': [2030, 2250], '(61.6%)': [2045], '(44.4%)': [2055], '(P=.121).': [2056], 'Previous': [2057, 3113], 'whole.7,14': [2070], 'work,': [2073], '(P=.37)': [2088], '(P=.53).': [2101], 'However,': [2102, 2264], 'elevation': [2105], 'Ridker': [2114, 2416, 2931], 'al,16': [2116], 'Malik': [2117, 2964], 'al17': [2119], 'Güray': [2121, 2340, 3003, 3007], 'al.18': [2123], 'China,': [2130], 'plasma': [2138, 2730], 'without': [2144, 2194], 'allele.10': [2147], 'fact': [2157], 'condition,': [2170], 'while': [2171], 'some': [2175], 'previous': [2178], 'chronic': [2181], 'prospective': [2185, 2436, 2992], 'Albert': [2187, 2394, 2410], 'al2': [2189], 'cardiovascular': [2198, 2205, 2248, 2274, 2400, 2642, 2950, 3065], 'predictive': [2203], 'atherosclerotic': [2210], 'progression': [2212, 2427], 'vessel': [2214], 'narrowing': [2215], 'stable': [2217], 'angina,': [2218], 'but': [2219], 'thrombosis/vessel': [2226], 'occlusion': [2227], 'infarction.': [2231], 'Discrepancies': [2232], 'can': [2239], 'attributed': [2241, 2297], 'racial/': [2244], 'risk.1The': [2249], '(P=.004).': [2263], 'Zakai': [2265, 3042], 'al19': [2267], 'older': [2279, 2648], 'adults,': [2280], 'they': [2282], 'only.': [2292], 'limited': [2300], 'number': [2301], 'female': [2303], 'ages': [2311], 'comparison': [2315], 'sICAM': [2331], '(P=.23);': [2333], 'al18': [2342], 'Damnjanovic': [2344, 3083], 'al.20In': [2346], 'conclusion,': [2347], 'suggest': [2350], 'Egyptians.': [2374], 'Circulating': [2375], 'disease.ARTICLE': [2392], 'REFERENCES:1.': [2393], 'MA.': [2395], '"Inflammatory': [2396], 'biomarkers,': [2397], 'race/ethnicity': [2398], 'disease"': [2401], '.': [2402, 2443, 2461, 2503, 2537, 2608, 2650, 2688, 2738, 2784, 2810, 2859, 2886, 2922, 2954, 2996, 3033, 3074, 3106], 'Nutr': [2403], 'Rev.': [2404], '2007;': [2405, 2890, 3078], '65:S234-8.': [2406], 'Google': [2407, 2447, 2467, 2510, 2542, 2566, 2614, 2656, 2699, 2749, 2791, 2816, 2865, 2892, 2928, 2961, 3000, 3039, 3080, 3111], 'Scholar2.': [2408], 'In:': [2409, 2449, 2469, 2512, 2544, 2568, 2616, 2658, 2701, 2751, 2793, 2818, 2867, 2894, 2930, 2963, 3002, 3041, 3082], 'MA,': [2411, 2795], 'Glynn': [2412], 'RJ,': [2413], 'Buring': [2414, 2935], 'JE,': [2415, 2936], 'PM.': [2417], '"Differential': [2418], 'effect': [2419], 'thrombosis:': [2434], 'Women’s': [2440], 'Health': [2441, 2786, 3072], 'Study"': [2442, 3073], 'Atherosclerosis.': [2444], '2008;': [2445], '197:297-302.': [2446], 'Scholar3.': [2448], 'Witkowska': [2450], 'AM,': [2451, 2620], 'Borawska': [2452], 'MH.': [2453], '"Soluble': [2454, 2635, 2982], '(sICAM-1):': [2458], 'An': [2459, 2852], 'overview"': [2460], 'Eur': [2462, 2860], 'Cytokine': [2463], 'Netw.': [2464], '2004;': [2465, 2508, 2863, 3037], '15:91-8.': [2466], 'Scholar4.': [2468], 'ZP,': [2471], 'Huo': [2472], 'Y,': [2473, 2477, 3008], 'Li': [2474], 'JP,': [2475], 'Xue': [2478, 2691, 2694, 2741, 2744], 'L,': [2479], 'Zhao': [2480], 'CY': [2481], 'al.': [2484, 2583, 2631, 2673, 2716, 2766, 2833, 2978, 3017, 3056], 'al..': [2487, 2586, 2634, 2676, 2719, 2769, 2836, 2981, 3020, 3059], '"Polymorphism': [2488], 'restenosis': [2496], 'patients"': [2502, 2783], 'Chin': [2504], 'Med': [2505], 'J': [2506, 2610, 2651, 2670, 2812, 2861, 2888, 2957, 3035, 3075], '(Engl).': [2507], '117:172-5.': [2509], 'Scholar5.': [2511], 'Harning': [2513], 'R,': [2514, 2578, 3045], 'Mainolfi': [2515], 'E,': [2516], 'Bystryn': [2517], 'JC,': [2518], 'Henn': [2519], 'M,': [2520, 2576, 3086], 'Merluzzi': [2521], 'VJ,': [2522], 'Rothlein': [2523], 'R.': [2524], '"Serum': [2525], 'intercelluar': [2529], 'molecule': [2531], 'malignant': [2535], 'melanoma"': [2536], 'Cancer': [2538], 'Res.': [2539], '1991;': [2540], '51:5003-5.': [2541], 'Scholar6.': [2543], 'Sambrook': [2545], 'J,': [2546, 2967], 'Fritsch': [2547], 'EF,': [2548], 'Maniatis': [2549], 'T.': [2550], 'Molecular': [2551], 'cloning:': [2552], 'manual': [2555], 'Cold': [2556, 2563], 'Spring.': [2557], '1989;': [2558], 'Vol': [2559], 'No.1NY:': [2560], 'Harbor': [2561], 'Laboratory': [2562], 'Spring': [2564], 'Harbor1-62.': [2565], 'Scholar7.': [2567], 'H,': [2570], 'Klein': [2571], 'RM,': [2572], 'Niederacher': [2573], 'D,': [2574], 'Du': [2575], 'Marx': [2577], 'Horlitz': [2579], 'M': [2580, 2975], '"C/T': [2587], '(exon': [2595], '6,': [2596], '469).A': [2598], 'factor': [2600], 'infarction"': [2607, 2885], 'Int': [2609, 3034], 'Cardiol.': [2611, 3036], '2002;': [2612], '84:171-7.': [2613], 'Scholar8.': [2615], 'Jenny': [2617, 3046], 'NS,': [2618, 3047], 'Arnold': [2619], 'Kuller': [2621], 'LH,': [2622], 'Sharrett': [2623], 'AR,': [2624, 2826, 2872, 3006], 'Fried': [2625], 'LP,': [2626], 'Psaty': [2627, 3048], 'BM': [2628], 'mortality': [2646], 'adults"': [2649], 'Thromb': [2652, 3076], 'Haemost.': [2653, 3077], '2006;': [2654, 2697, 2747, 2926], '4:107-13.': [2655], 'Scholar9.': [2657], 'SR,': [2660], 'Xu': [2661, 2667], 'LX,': [2662], 'Gao': [2663], 'QQ,': [2664], 'HQ,': [2666], 'BS,': [2668], 'Lin': [2669], '"[The': [2677], 'correlation': [2678], 'disease]"': [2687, 2737, 3105], 'Zhonghua': [2689, 2739], 'Yi': [2690, 2692, 2740, 2742], 'Chuan': [2693, 2743], 'Za': [2695, 2745], 'Zhi.': [2696, 2746], '23:205-7.': [2698], 'Scholar10.': [2700], 'FH,': [2703], 'Shang': [2704], 'Q,': [2705], 'Wen': [2706], 'PE,': [2707], 'Su': [2708], 'GH,': [2709], 'Wu': [2710], 'JM,': [2711], 'Tian': [2712], 'Q': [2713], '"[A': [2720], 'ICAM1': [2726, 2729], '23:195-7.': [2748], 'Scholar11.': [2750], 'O,': [2753, 2973], 'Zahra': [2754], 'A,': [2755, 2757, 2759, 2896], 'Sayed': [2756], 'Refaat': [2758], 'El-Khaiat': [2760], 'Z,': [2761], 'Hegazy': [2762], 'G': [2763], '"Role': [2770], 'E-selectin': [2774], 'PAOD': [2780], 'Vasc': [2785], 'Manag.': [2788], '2010;': [2789], '6:9-15.': [2790], 'Scholar12.': [2792], 'Lefer': [2796], 'DJ,': [2797], 'Granger': [2798], 'DN.': [2799], '"Postischemic': [2800], 'reactivity': [2803], 'preserved': [2805], 'molecule-deficient': [2808], 'mice"': [2809], 'Am': [2811], 'Physiol.': [2813], '1997;': [2814], '273:H2721-5.': [2815], 'Scholar13.': [2817], 'PG,': [2820], 'Spence': [2821], 'MS,': [2822], 'Patterson': [2823], 'CC,': [2824], 'Allen': [2825], 'Murphy': [2827], 'G,': [2828, 3084], 'Belton': [2829], '"The': [2837, 2899], 'ischaemic': [2849], 'disease:': [2851, 2990], 'investigation': [2853], 'family-based': [2855], 'tests': [2856], 'association"': [2858], 'Immunogenet.': [2862], '31:201-6.': [2864], 'Scholar14.': [2866], 'B,': [2869, 3088], 'Abdi': [2870], 'Ardekani': [2871], 'Arandi': [2873], 'N.': [2874, 2938], '"ICAM-1': [2875], '(G241R,': [2877], 'K469E),': [2878], 'artery': [2881, 3104], 'Iran': [2887], 'Immunol.': [2889], '4:227-35.': [2891], 'Scholar15.': [2893], 'Milutinovic': [2895], 'Petrovic': [2897], 'D.': [2898], 'Polymorphism': [2901], 'Intracellular': [2904], 'Adhesion': [2905], 'Molecule': [2906], 'Gene': [2909], 'Is': [2910], 'Not': [2911], 'Associated': [2912], 'Myocardial': [2914], 'Infarction': [2915], 'Caucasians': [2917], 'Type': [2919], 'Diabetes"': [2921], 'Folia': [2923], 'Biol': [2924], '(Praha).': [2925], '52:79-80.': [2927], 'Scholar16.': [2929], 'PM,': [2932], 'Hennekens': [2933], 'CH,': [2934], 'Rifai': [2937], '"C-reactive': [2939], 'prediction': [2948, 2986], 'women"': [2953], 'N': [2955], 'Engl': [2956], 'Med.': [2958], '2000;': [2959], '342:836-43.': [2960], 'Scholar17.': [2962], 'I,': [2965], 'Danesh': [2966], 'Whincup': [2968], 'P,': [2969], 'Bhatia': [2970], 'V,': [2971], 'Papacosta': [2972], 'Walker': [2974], 'meta-analysis"': [2995], 'Lancet.': [2997], '2001;': [2998], '358:971-6.': [2999], 'Scholar18.': [3001], 'U,': [3004], 'Erbay': [3005], 'Yilmaz': [3009], 'MB,': [3010], 'Boyaci': [3011], 'AA,': [3012], 'Sasmaz': [3013], 'H': [3014], '"Levels': [3021], 'various': [3027], 'presentations': [3029], 'atherosclerosis"': [3032], '96:235-40.': [3038], 'Scholar19.': [3040], 'NA,': [3043], 'Katz': [3044], 'BM,': [3049], 'Reiner': [3050], 'AP,': [3051], 'Schwartz': [3052], 'SM': [3053], '"Inflammation': [3060], 'hemostasis': [3062], 'biomarkers': [3063], 'elderly:': [3069], 'Cardiovascular': [3071], '5:1128-35.': [3079], 'Scholar20.': [3081], 'Jelic': [3085], 'Dindic': [3087], 'Ilic': [3089], 'S.': [3090], '"[Serum': [3091], 'concentration': [3092], 'adhesive': [3095], 'forms': [3101], 'Vojnosanit': [3107], 'Pregl.': [3108], '2009;': [3109], '66:265-70.': [3110], 'Scholar': [3112], 'article': [3114, 3116, 3143], 'Next': [3115], 'FiguresReferencesRelatedDetails': [3117], 'Volume': [3118], '30,': [3119], 'Issue': [3120], '6Nov–Dec': [3121], '2010': [3122, 3132], 'Metrics': [3123], 'History': [3124], 'Received1': [3125], 'January': [3126], '2010Accepted1': [3127], '2010Published': [3129], 'online2': [3130], 'December': [3131], 'InformationCopyright': [3133], '©': [3134], '2010,': [3135], 'Annals': [3136], 'Saudi': [3138], 'MedicineThis': [3139], 'open-access': [3142], 'distributed': [3144], 'under': [3145], 'Creative': [3150], 'Commons': [3151], 'Attribution': [3152], 'License,': [3153], 'permits': [3155], 'unrestricted': [3156], 'use,': [3157], 'distribution,': [3158], 'reproduction': [3160], 'medium,': [3163], 'provided': [3164], 'work': [3167], 'properly': [3169], 'cited.PDF': [3170], 'download': [3171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2327346284', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-14T18:12:25.886981', 'created_date': '2016-06-24'}