Title: NMDA RECEPTOR ANTIBODIES IN FIRST EPISODE PSYCHOSIS: PREVALENCE AND CLINICAL PHENOTYPE
Abstract: We report the case of a 14-year-old girl who was diagnosed with N-methyl-d-aspartate (NMDA)-receptor encephalitis, with severe features and autonomic instability, requiring intensive care unit admission. She had poor clinical response to the first-line therapies, she was then started on Rituximab and 6 cycles of Cytoxan infusion. She responded to Bortezomib therapy within 2 weeks of initiation, and with long-term sustenance of improvement in the long-term, also demonstrated by an improvement in NMDA titers . As far as we know, this is the first report of use of Bortezomib therapy in a child with refractory NMDA-receptor encephalitis.
Publication Year: 2014
Publication Date: 2014-04-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 2
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