Title: CEUS in the Characterization of Portal Vein Thrombosis
Abstract: Brief Description of the Purpose of the StudyRetrospective evaluation of the effectiveness of CEUS in the differential diagnosis between benign and malignant thrombus of the portal vein.Methods85 patients underwent CEUS in the period from 06/2005 to 12/2011, so as to research portal vein thrombosis, all with chronic liver disease and hepatocellular carcinoma suggesting nodules. In order to confirm the nature of the thrombus, other imaging exams such as CT and MRI were analyzed over a period of 6 months from the date of CEUS. Considered benign (hematic): thrombus which remained stable, decreased or recanalized over time, showed no enhancement or arterial spectrum after the contrast. Considered malignant in case of disruption of the vessel wall, increased in size after the first examination, and showed enhancement in the arterial phase or arterial spectrum after contrast.Main Results15/85 patients had no portal vein thrombosis, 06 were not found in the system and 25 lost follow up, remaining 39 patients. 22/39 were malignant and 17/39, benign. The CEUS was conclusive in 37/39 patients [kappa = 0.897 (p < 0.0000001)]; sensitivity of 90.9% and specificity of 100%.Importance of the ConclusionsCEUS proved to be an excellent diagnostic method for assessing the nature of the thrombus in patients with chronic liver disease complicated with portal vein thrombosis. Brief Description of the Purpose of the StudyRetrospective evaluation of the effectiveness of CEUS in the differential diagnosis between benign and malignant thrombus of the portal vein. Retrospective evaluation of the effectiveness of CEUS in the differential diagnosis between benign and malignant thrombus of the portal vein. Methods85 patients underwent CEUS in the period from 06/2005 to 12/2011, so as to research portal vein thrombosis, all with chronic liver disease and hepatocellular carcinoma suggesting nodules. In order to confirm the nature of the thrombus, other imaging exams such as CT and MRI were analyzed over a period of 6 months from the date of CEUS. Considered benign (hematic): thrombus which remained stable, decreased or recanalized over time, showed no enhancement or arterial spectrum after the contrast. Considered malignant in case of disruption of the vessel wall, increased in size after the first examination, and showed enhancement in the arterial phase or arterial spectrum after contrast. 85 patients underwent CEUS in the period from 06/2005 to 12/2011, so as to research portal vein thrombosis, all with chronic liver disease and hepatocellular carcinoma suggesting nodules. In order to confirm the nature of the thrombus, other imaging exams such as CT and MRI were analyzed over a period of 6 months from the date of CEUS. Considered benign (hematic): thrombus which remained stable, decreased or recanalized over time, showed no enhancement or arterial spectrum after the contrast. Considered malignant in case of disruption of the vessel wall, increased in size after the first examination, and showed enhancement in the arterial phase or arterial spectrum after contrast. Main Results15/85 patients had no portal vein thrombosis, 06 were not found in the system and 25 lost follow up, remaining 39 patients. 22/39 were malignant and 17/39, benign. The CEUS was conclusive in 37/39 patients [kappa = 0.897 (p < 0.0000001)]; sensitivity of 90.9% and specificity of 100%. 15/85 patients had no portal vein thrombosis, 06 were not found in the system and 25 lost follow up, remaining 39 patients. 22/39 were malignant and 17/39, benign. The CEUS was conclusive in 37/39 patients [kappa = 0.897 (p < 0.0000001)]; sensitivity of 90.9% and specificity of 100%. Importance of the ConclusionsCEUS proved to be an excellent diagnostic method for assessing the nature of the thrombus in patients with chronic liver disease complicated with portal vein thrombosis. CEUS proved to be an excellent diagnostic method for assessing the nature of the thrombus in patients with chronic liver disease complicated with portal vein thrombosis.
Publication Year: 2013
Publication Date: 2013-04-10
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot