Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2322799757', 'doi': 'https://doi.org/10.1042/bj1200195', 'title': 'The subcellular localization of di- and tri-peptide hydrolase activity in guinea-pig small intestine', 'display_name': 'The subcellular localization of di- and tri-peptide hydrolase activity in guinea-pig small intestine', 'publication_year': 1970, 'publication_date': '1970-11-01', 'ids': {'openalex': 'https://openalex.org/W2322799757', 'doi': 'https://doi.org/10.1042/bj1200195', 'mag': '2322799757', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/5494224', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1179584'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj1200195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210234214', 'display_name': 'Biochemical Journal', 'issn_l': '0306-3283', 'issn': ['0306-3283'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1179584?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048022602', 'display_name': 'Timothy J. Peters', 'orcid': 'https://orcid.org/0000-0003-3690-5293'}, 'institutions': [{'id': 'https://openalex.org/I90344618', 'display_name': 'Medical Research Council', 'ror': 'https://ror.org/03x94j517', 'country_code': 'GB', 'type': 'government', 'lineage': ['https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'T. J. Peters', 'raw_affiliation_strings': ['Medical Research Council Intestinal Malabsorption Group, Department of Medicine, Royal Postgraduate Medical School, Du Cane Road, London W.12, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Medical Research Council Intestinal Malabsorption Group, Department of Medicine, Royal Postgraduate Medical School, Du Cane Road, London W.12, U.K.', 'institution_ids': ['https://openalex.org/I90344618']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5048022602'], 'corresponding_institution_ids': ['https://openalex.org/I90344618'], 'apc_list': None, 'apc_paid': None, 'fwci': 6.172, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 111, 'citation_normalized_percentile': {'value': 0.90147, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '120', 'issue': '1', 'first_page': '195', 'last_page': '203'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11561', 'display_name': 'Protein Hydrolysis and Bioactive Peptides', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11561', 'display_name': 'Protein Hydrolysis and Bioactive Peptides', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12505', 'display_name': 'Peptidase Inhibition and Analysis', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11294', 'display_name': 'Infant Nutrition and Health', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tripeptide', 'display_name': 'Tripeptide', 'score': 0.8032272}, {'id': 'https://openalex.org/keywords/brush-border', 'display_name': 'Brush border', 'score': 0.7931701}, {'id': 'https://openalex.org/keywords/cell-fractionation', 'display_name': 'Cell fractionation', 'score': 0.66479874}, {'id': 'https://openalex.org/keywords/digestion', 'display_name': 'Digestion', 'score': 0.44681433}], 'concepts': [{'id': 'https://openalex.org/C167392928', 'wikidata': 'https://www.wikidata.org/wiki/Q4820777', 'display_name': 'Tripeptide', 'level': 3, 'score': 0.8032272}, {'id': 'https://openalex.org/C5426402', 'wikidata': 'https://www.wikidata.org/wiki/Q2462753', 'display_name': 'Brush border', 'level': 4, 'score': 0.7931701}, {'id': 'https://openalex.org/C2778815084', 'wikidata': 'https://www.wikidata.org/wiki/Q79803', 'display_name': 'Guinea pig', 'level': 2, 'score': 0.74073833}, {'id': 'https://openalex.org/C27239569', 'wikidata': 'https://www.wikidata.org/wiki/Q189029', 'display_name': 'Cell fractionation', 'level': 3, 'score': 0.66479874}, {'id': 'https://openalex.org/C2776879804', 'wikidata': 'https://www.wikidata.org/wiki/Q7630919', 'display_name': 'Subcellular localization', 'level': 3, 'score': 0.63722193}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.6299911}, {'id': 'https://openalex.org/C2777882243', 'wikidata': 'https://www.wikidata.org/wiki/Q11090', 'display_name': 'Small intestine', 'level': 2, 'score': 0.61347765}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.50240684}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.47463807}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.464216}, {'id': 'https://openalex.org/C2781357212', 'wikidata': 'https://www.wikidata.org/wiki/Q5275608', 'display_name': 'Digestion (alchemy)', 'level': 2, 'score': 0.44681433}, {'id': 'https://openalex.org/C2779281246', 'wikidata': 'https://www.wikidata.org/wiki/Q172847', 'display_name': 'Peptide', 'level': 2, 'score': 0.42232478}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.38380593}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.1786085}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.12110308}, {'id': 'https://openalex.org/C130316041', 'wikidata': 'https://www.wikidata.org/wiki/Q189206', 'display_name': 'Vesicle', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004150', 'descriptor_name': 'Dipeptidases', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D004063', 'descriptor_name': 'Digestion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004150', 'descriptor_name': 'Dipeptidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004151', 'descriptor_name': 'Dipeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004151', 'descriptor_name': 'Dipeptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D006168', 'descriptor_name': 'Guinea Pigs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008247', 'descriptor_name': 'Lysosomes', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008861', 'descriptor_name': 'Microsomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008861', 'descriptor_name': 'Microsomes', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj1200195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210234214', 'display_name': 'Biochemical Journal', 'issn_l': '0306-3283', 'issn': ['0306-3283'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1179584', 'pdf_url': 'https://europepmc.org/articles/pmc1179584?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1179584', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/5494224', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1179584', 'pdf_url': 'https://europepmc.org/articles/pmc1179584?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W10238197', 'https://openalex.org/W102412069', 'https://openalex.org/W147020853', 'https://openalex.org/W1497053054', 'https://openalex.org/W1523386046', 'https://openalex.org/W1525248227', 'https://openalex.org/W1582080277', 'https://openalex.org/W170430538', 'https://openalex.org/W1775749144', 'https://openalex.org/W1802229984', 'https://openalex.org/W183886054', 'https://openalex.org/W1863392971', 'https://openalex.org/W1969490731', 'https://openalex.org/W1970712944', 'https://openalex.org/W1979699652', 'https://openalex.org/W1996608458', 'https://openalex.org/W1998560657', 'https://openalex.org/W1998808139', 'https://openalex.org/W2003933471', 'https://openalex.org/W2010901745', 'https://openalex.org/W2020860826', 'https://openalex.org/W2025742247', 'https://openalex.org/W2043493463', 'https://openalex.org/W2061471294', 'https://openalex.org/W2062614907', 'https://openalex.org/W2067624080', 'https://openalex.org/W2089049766', 'https://openalex.org/W2092777953', 'https://openalex.org/W2105216834', 'https://openalex.org/W2118723661', 'https://openalex.org/W2145734899', 'https://openalex.org/W2164295514', 'https://openalex.org/W2216516016', 'https://openalex.org/W2266961469', 'https://openalex.org/W2328852953', 'https://openalex.org/W2384408522', 'https://openalex.org/W2405684308', 'https://openalex.org/W2414348796', 'https://openalex.org/W2414623057', 'https://openalex.org/W2414771379', 'https://openalex.org/W2414938352', 'https://openalex.org/W2417997171', 'https://openalex.org/W2427402051', 'https://openalex.org/W2437248397', 'https://openalex.org/W2468691704', 'https://openalex.org/W2469837345', 'https://openalex.org/W2771493373'], 'related_works': ['https://openalex.org/W4245135533', 'https://openalex.org/W3196496308', 'https://openalex.org/W3034599796', 'https://openalex.org/W2329306935', 'https://openalex.org/W2286209825', 'https://openalex.org/W2171240256', 'https://openalex.org/W2098649277', 'https://openalex.org/W2061291029', 'https://openalex.org/W1738478684', 'https://openalex.org/W1602491094'], 'abstract_inverted_index': {'1.': [0], 'Two': [1], 'different': [2], 'subcellular': [3, 34], 'fractionation': [4], 'techniques': [5], 'were': [6, 24, 55, 76], 'applied': [7], 'to': [8, 97], 'guinea-pig': [9], 'intestinal': [10], 'mucosa': [11], 'and': [12, 41, 102], 'the': [13, 16, 21, 33, 58, 61, 66, 79, 83, 88, 98, 103], 'composition': [14], 'of': [15, 36, 51, 72, 94, 106], 'brush': [17, 80], 'borders': [18], 'prepared': [19], 'by': [20], 'two': [22], 'methods': [23], 'compared.': [25], '2.': [26], 'By': [27], 'using': [28], 'a': [29], 'kinetic': [30], 'assay': [31], 'system': [32], 'distribution': [35], 'activity': [37, 52, 73], 'against': [38, 53, 74], 'ten': [39], 'dipeptides': [40, 54], 'five': [42], 'tripeptides': [43, 75], 'was': [44], 'studied.': [45], '3.': [46], 'Only': [47], 'small': [48], 'amounts': [49, 70], '(5–10%)': [50], 'found': [56, 77], 'in': [57, 65, 78, 87, 100, 108], 'brush-border': [59], 'region,': [60], 'enzymes': [62], 'being': [63], 'concentrated': [64], 'cytosol.': [67], '4.': [68], 'Significant': [69], '(10–60%)': [71], 'border': [81], 'with': [82], 'remainder': [84], 'largely': [85], 'present': [86], 'soluble': [89], 'fraction.': [90], '5.': [91], 'The': [92], 'relevance': [93], 'these': [95], 'studies': [96], 'localization': [99], 'vivo': [101], 'possible': [104], 'role': [105], 'peptidases': [107], 'protein': [109], 'digestion': [110], 'is': [111], 'discussed.': [112]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2322799757', 'counts_by_year': [{'year': 2016, 'cited_by_count': 2}], 'updated_date': '2024-12-13T15:36:43.899551', 'created_date': '2016-06-24'}