Title: Production of extracts from olive by-products and evaluation of their cytotoxic/cytostatic activity
Abstract: Over the years, several studies have related olive to a low incidence of several diseases, including cancer. This may be due to the phenolic compounds encountered in olive products. Recent studies have shown that the wastes produced during olive processing are valuable sources of phenols. In the present work, extracts were obtained from various by-products generated during olive processing, specifically: olive fruit debittering, olive oil mill waste, olive paste and olive leaves, and were chemically characterized. Furthermore, their cytotoxic/cytostatic effects were evaluated against a panel of various cancer cell lines as determined by MTT assays. Our results show that these extracts are rich in phenolic compounds, mainly oleuropein 1 and its degradation molecule hydroxytyrosol 2, and exhibit promising biological activities.
Publication Year: 2012
Publication Date: 2012-07-01
Language: en
Type: article
Indexed In: ['crossref']
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