Title: Novel synthesis and reactions of pyrazolyl-substituted tetrahydrothieno[2,3-<i>c</i>]isoquinoline derivatives
Abstract: Abstract Treatment of isoquinolinecarboxamide 4a with triethyl orthoformate, chloroacetyl chloride or carbon disulfide afforded the pyrimidinone 7 , oxopyrimidinethione 12 and chloromethylpyrimidinone 18 , respectively. These products were used as versatile starting materials for synthesis of other heterocyclic compounds. The heterocyclic hydrazide 6 was also obtained.