Enantioselective Construction of Quaternary Carbon Stereocenter via Palladium-Catalyzed Asymmetric Allylic Alkylation of Lactones

Name: Work Video:
Duration: 3 min 30 s
Description: An efficient and practical method for the synthesis of α,α-disubstituted six-membered lactones was developed. Enantioselective construction of quaternary carbon centers by utilizing Pd-catalyzed asymmetric allylic alkylation proved its feasibility.
Ping Fang; Xue‐Long Hou; Xiaohui Li; Shili Wan; Di Chen; Qing Liu; Chang‐Hua Ding
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