Title: A STUDY OF NON ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH METABOLIC SYNDROME
Abstract: This study was conducted to know the relation of non-alcoholic fatty liver disease (non-alcoholic steatohepatitis & cirrhosis) with metabolic syndrome.MATERIAL AND METHODS: 60 cases were selected.Out of them 30 were non-alcoholic steatohepatitis and 30 cirrhosis along with 30 healthy controls.Parameters of metabolic syndrome and liver function which are waist circumference, blood pressure, fasting plasma glucose, total triglycerides, high density lipo-protein cholesterol, total bilirubin, alanine amino transferase, alkaline phosphotase, total proteins and albumin were measured.STATISTICAL ANALYSIS: All values were expressed as mean ± SD.The results obtained were analyzed statistically using the unpaired student 't'test to evaluate the significance of differences between the mean values. RESULTS:The values of waist circumference, fasting plasma glucose, systolic blood pressure, total triglycerides, total bilirubin, alanine-amino-transferase and alkaline phosphotase were raised in non-alcoholic steatohepatitis and cirrhosis patients.The level of high density lipoprotein cholesterol was decreased in non-alcoholic steatohepatitis and cirrhosis patients.The level of albumin was decreased in cirrhosis patients.CONCLUSION: On the basis of our results it may be concluded that metabolic syndrome causes nonalcoholic fatty liver disease.