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'https://openalex.org/W2146750742', 'https://openalex.org/W2150004800', 'https://openalex.org/W2156043827', 'https://openalex.org/W2158033922', 'https://openalex.org/W2159090847', 'https://openalex.org/W2168735089', 'https://openalex.org/W2170297360', 'https://openalex.org/W2171768289'], 'related_works': ['https://openalex.org/W994139557', 'https://openalex.org/W2471448424', 'https://openalex.org/W2142394429', 'https://openalex.org/W2142354708', 'https://openalex.org/W2135635297', 'https://openalex.org/W2078629046', 'https://openalex.org/W2070018025', 'https://openalex.org/W2052143814', 'https://openalex.org/W2036055832', 'https://openalex.org/W2031333457'], 'abstract_inverted_index': {'Growth': [0, 198, 396, 700, 902, 968, 1007, 1207, 1412, 1451, 1810, 2094, 2209, 2372], 'hormone': [1, 199, 397, 416, 513, 614, 813, 858, 903, 969, 1008, 1025, 1208, 1225, 1311, 1413, 1452, 1469, 1811, 2095, 2210, 2373, 2426], '(GH)': [2, 200, 398], 'acutely': [3, 201, 1173], 'stimulates': [4, 202, 672], 'lipolysis': [5, 131, 203, 329, 1307], 'and': [6, 14, 39, 46, 87, 108, 121, 132, 204, 212, 237, 244, 285, 306, 319, 330, 420, 451, 456, 517, 559, 600, 604, 609, 633, 674, 775, 826, 859, 879, 908, 951, 1015, 1023, 1062, 1105, 1215, 1223, 1259, 1306, 1338, 1346, 1351, 1383, 1459, 1467, 1582, 1602, 1623, 1726, 1746, 1754, 1852, 1935, 1993, 2011, 2059, 2258, 2263, 2300, 2424, 2500, 2504, 2529, 2546, 2624, 2647, 2686, 2693, 2705, 2741, 2769, 2823, 2866, 2875, 2879, 2883, 2887, 2895, 2903, 2907, 2911, 2960, 3024, 3085, 3123, 3164, 3217, 3222, 3250, 3270, 3340, 3363, 3515, 3542, 3692, 3707, 3715, 3735, 3745, 3841, 3853, 3858, 3865, 3895, 3907, 3912, 3919, 3942, 3967, 3975, 3987, 4010, 4056, 4076, 4078, 4085, 4095, 4117, 4155, 4165, 4170, 4189, 4234, 4243], 'fat': [7, 205, 880], 'oxidation,': [8, 206], 'a': [9, 52, 127, 207, 250, 325, 442, 461, 511, 795, 1055, 1678, 1702, 1789, 1896, 1911, 2044, 2077, 2143, 2154, 2157, 2163, 2184, 2328, 2331, 2341, 2381, 2550, 2561, 2781, 2797, 2932, 3034, 3174, 3240, 3400, 3477, 3575, 3602, 3614, 3646, 3657, 3891, 3950, 4088, 4096, 4150, 4278], 'process': [10, 208], 'that': [11, 171, 209, 369, 484, 670, 730, 752, 764, 1135, 1161, 1531, 3018, 3934, 4113, 4142], 'operates': [12, 210], 'postabsorptively': [13, 211], 'involves': [15, 213], 'activation': [16, 214], 'of': [17, 51, 81, 89, 92, 134, 151, 157, 165, 174, 187, 215, 249, 279, 287, 290, 332, 349, 355, 363, 372, 385, 403, 414, 437, 481, 493, 510, 597, 635, 676, 768, 772, 777, 834, 853, 865, 905, 941, 1019, 1119, 1147, 1166, 1186, 1188, 1219, 1309, 1348, 1385, 1392, 1463, 1485, 1491, 1513, 1533, 1580, 1584, 1621, 1670, 1673, 1689, 1693, 1701, 1731, 1743, 1757, 1760, 1774, 1788, 1866, 1883, 1902, 1949, 2028, 2046, 2057, 2150, 2254, 2313, 2334, 2375, 2417, 2422, 2467, 2486, 2563, 2569, 2664, 2758, 2783, 2991, 3167, 3220, 3280, 3377, 3404, 3421, 3465, 3480, 3556, 3591, 3618, 3625, 3643, 3730, 3740, 4004, 4091, 4109, 4152, 4174, 4194, 4203, 4208, 4237, 4265], 'the': [18, 22, 79, 85, 98, 138, 154, 178, 216, 220, 277, 283, 296, 336, 352, 376, 545, 737, 750, 835, 854, 863, 1140, 1145, 1189, 1547, 1652, 1667, 1682, 1686, 1699, 2177, 2249, 2276, 2418, 2432, 2492, 2502, 2535, 2557, 2570, 2598, 2608, 2616, 2638, 2651, 2662, 2712, 2716, 2749, 2846, 2867, 2941, 2975, 2985, 2992, 3019, 3042, 3194, 3232, 3393, 3492, 3513, 3522, 3596, 3677, 3712, 3960, 3976, 3988, 3999, 4023, 4030, 4044, 4063, 4100, 4103, 4110, 4121, 4136, 4263], 'JAK-STAT': [19, 217], 'pathway': [20, 101, 218, 299, 837, 1143, 4124], 'in': [21, 26, 42, 59, 72, 84, 97, 110, 130, 195, 219, 224, 240, 257, 270, 282, 295, 308, 328, 393, 406, 423, 441, 469, 474, 521, 533, 607, 619, 639, 651, 668, 744, 760, 786, 838, 912, 930, 979, 1010, 1012, 1064, 1067, 1108, 1112, 1158, 1177, 1182, 1184, 1210, 1212, 1256, 1262, 1300, 1359, 1423, 1454, 1456, 1538, 1558, 1564, 1589, 1603, 1627, 1658, 1709, 1713, 1769, 1821, 1855, 1859, 1910, 1938, 1942, 1983, 2074, 2076, 2105, 2220, 2273, 2316, 2345, 2379, 2384, 2419, 2431, 2470, 2495, 2519, 2637, 2697, 2731, 2789, 2827, 2834, 2918, 2931, 2967, 2971, 3007, 3047, 3144, 3148, 3159, 3205, 3231, 3252, 3296, 3366, 3370, 3396, 3491, 3504, 3545, 3549, 3578, 3616, 3649, 3844, 3890, 3898, 3938, 3949, 3965, 4039, 4042, 4066, 4120, 4206, 4277], 'target': [23, 221, 1486, 1761], 'tissue;': [24, 222], 'no': [25, 223, 3025, 3502], 'vivo': [27, 225, 1011, 1113, 1178, 1211, 1455, 1860, 1943, 2420, 2464, 3371, 3550], 'data': [28, 226, 759, 1779, 1787, 3285, 4094], 'exist': [29, 227], 'regarding': [30, 228], 'subsequent': [31, 229, 1747], 'GH-regulated': [32, 70, 230, 268], 'gene': [33, 124, 159, 193, 231, 322, 357, 391, 605, 1389, 1516, 1587, 1707, 2329, 2377, 2429, 2468, 2668, 2980, 3951, 4053, 4079, 4092], 'transcription.': [34, 232], 'We': [35, 233, 2119, 2279], 'obtained': [36, 234, 1780, 2298, 2587], 'serum': [37, 60, 235, 258, 3253, 3313, 3401, 3462, 3505, 3579, 3757, 3769, 3785, 3800, 3821, 3837, 3845, 3884, 3899], 'samples': [38, 236, 2017, 2235, 2496, 2516, 2689, 3004, 3125, 3977, 4210], 'muscle': [40, 238, 408, 546, 610, 745, 839, 1014, 1070, 1111, 1151, 1183, 1214, 1258, 1458, 1541, 1561, 1592, 1630, 1712, 1723, 1858, 1941, 2122, 2144, 2158, 2293, 2319, 2514, 3043, 3369, 3548, 3939], 'biopsies': [41, 239, 1724, 2000, 2123, 2178, 2294, 3044, 3986, 3990], 'human': [43, 196, 241, 394, 424, 761, 931, 1013, 1068, 1109, 1159, 1213, 1263, 1457, 1539, 1710, 1856, 1939, 2317, 2471, 3367, 3546], 'subjects': [44, 242, 762, 1160, 1264, 1721], 'before': [45, 243, 543, 1725, 2299, 3759, 3771, 3787, 3802, 3823, 3839, 3849, 3861, 3886, 3903, 3915, 3941], '2': [47, 245, 487, 1727, 2026, 2241, 2793, 2798, 3071, 3142, 3860, 3914, 4137], 'h': [48, 246, 488, 1728, 2169, 2186, 2794, 2799, 3143, 3158, 4138], 'after': [49, 143, 247, 341, 486, 1729, 1964, 1978, 1995, 2148, 2303, 2818, 3582, 3605, 3688, 3704, 3711, 3728, 3854, 3866, 3908, 3920, 3945, 3992, 4179], 'administration': [50, 248, 1730], 'GH': [53, 251, 438, 464, 577, 636, 671, 747, 1074, 1106, 1116, 1148, 1165, 1179, 1253, 1270, 1492, 1537, 1567, 1578, 1704, 1734, 1766, 1853, 1863, 1936, 1946, 1967, 1981, 2032, 2058, 2151, 2165, 2306, 2314, 2348, 2814, 3364, 3374, 3394, 3402, 3434, 3452, 3459, 3463, 3506, 3514, 3543, 3553, 3573, 3592, 3644, 3695, 3706, 3716, 3731, 3741, 3946, 3955, 3993, 4180], 'bolus.': [54, 252, 1735], 'A': [55, 253, 2581, 2699, 3009], 'significant': [56, 254], '(∼75%)': [57, 255], 'elevation': [58, 256], 'FFA': [61, 176, 183, 259, 374, 381, 538, 732, 788, 3341, 3580, 3617, 3626, 3650, 3671], 'levels': [62, 260, 450, 789, 1669, 2506, 3420, 3464, 3581, 3686, 3701, 3722, 3758, 3770, 3786, 3801, 3822, 3838, 3885, 4003], 'was': [63, 146, 261, 344, 1696, 1738, 1763, 1767, 2146, 2160, 2271, 2489, 2532, 2539, 2560, 2572, 2586, 2595, 2635, 2671, 2681, 2709, 2752, 2775, 2837, 2969, 2982, 3012, 3022, 3191, 3203, 3227, 3286, 3300, 3309, 3325, 3431, 3447, 3507, 3593, 3629, 3672, 3738, 3973, 4129], 'recorded': [64, 262, 473, 1157, 3508], 'post': [65, 263], 'GH.': [66, 264, 1690], 'Microarray': [67, 265, 1736, 2415, 4186], 'identified': [68, 266, 2326, 3948, 4048], '79': [69, 267, 3957], 'genes': [71, 83, 95, 114, 269, 281, 293, 312, 1487, 1534, 1674, 1745, 1762, 2324, 2488, 2685, 2714, 3958, 4006, 4019, 4031, 4064, 4111, 4141, 4283], 'muscle.': [73, 197, 271, 395], 'With': [74, 272], 'qRT-PCR,': [75, 273], 'we': [76, 274], 'then': [77, 275, 2951, 3165], 'examined': [78, 276, 2490], 'expression': [80, 160, 194, 278, 358, 392, 606, 907, 1358, 1588, 1626, 1668, 1708, 1759, 2378, 2430, 2469, 2669, 2981, 3966, 4207], 'selected': [82, 280, 4195], 'presence': [86, 284], 'absence': [88, 286], 'glucose-induced': [90, 288], 'suppression': [91, 133, 150, 289, 331, 348, 480, 771, 940, 1773, 3604, 3627, 3659], 'lipolysis.': [93, 152, 166, 291, 350, 364, 1775], 'Four': [94, 292], 'involved': [96, 129, 294, 327, 4065, 4119], 'JAK-STAT5': [99, 297, 4122], 'signaling': [100, 298, 944, 1009, 1107, 1142, 1181, 1209, 1255, 1387, 1453, 1586, 1854, 1937, 3365, 3544, 4123], 'were': [102, 300, 1908, 2004, 2018, 2052, 2179, 2236, 2246, 2325, 2517, 2612, 2645, 2729, 2787, 2821, 2832, 2871, 2916, 3005, 3028, 3045, 3092, 3101, 3116, 3126, 3169, 3182, 3237, 3254, 3318, 3723, 3935, 3947, 4012, 4020, 4125, 4160, 4177], 'regulated': [103, 301, 1535, 2487, 2713, 4134, 4178, 4308], 'by': [104, 148, 190, 302, 346, 388, 478, 539, 612, 948, 1072, 1376, 1536, 1634, 2134, 2248, 2541, 2655, 2690, 2825, 2845, 3103, 3128, 3171, 3193, 3207, 3288, 3327, 3595, 3601, 3676, 4014, 4022, 4102, 4184, 4258, 4284], 'GH,': [105, 144, 303, 342, 769, 1758], 'including': [106, 304, 1740], 'SOCS1–3': [107, 305, 4116], 'CISH,': [109, 307, 4009, 4118], 'addition': [111, 309], 'to': [112, 163, 310, 361, 445, 460, 537, 1164, 1267, 1680, 1697, 2267, 2275, 2308, 2347, 2354, 2607, 2615, 2661, 2796, 2807, 3418, 3474, 3476, 3656, 4028, 4132, 4146, 4212], 'three': [113, 311, 1916, 2067], 'associated': [115, 313, 642, 705, 831, 3449, 4266], 'with': [116, 314, 447, 490, 643, 682, 706, 832, 1566, 1605, 1771, 1895, 1985, 2031, 2043, 2054, 2189, 2340, 2597, 2650, 2658, 2754, 2801, 3214, 3450, 3634, 3756, 3768, 3784, 3799, 3820, 3836, 3883, 4262, 4270], 'insulin': [117, 315, 446, 702, 792, 809, 860, 866, 919, 934, 943, 971, 1065, 1304, 1415, 1606, 1813, 2097, 2190, 2212, 3518, 4153], 'action:': [118, 316], 'NFκB1A,': [119, 317, 4163], 'PIK3C2B,': [120, 318, 4164], 'PRKAG2.': [122, 320, 4166], 'The': [123, 321, 435, 1662, 1691, 2069, 2269, 2567, 2913, 2965, 2978, 3225, 3429, 3623, 4035], 'encoding': [125, 323], 'ANGPTL4,': [126, 324], 'protein': [128, 326, 421, 2505, 2892, 3114, 3120, 3124, 3180, 3190, 3314, 4295, 4317], 'LPL': [135, 188, 333, 386, 580], 'activity,': [136, 334], 'exhibited': [137, 335], 'most': [139, 337], 'pronounced': [140, 338], 'upregulation': [141, 339], '(5.6-fold)': [142, 340], 'which': [145, 343, 1393, 1676, 1786, 2819, 3415, 4043], 'abrogated': [147, 345], 'concomitant': [149, 347, 3597, 3694], 'Therefore,': [153, 351], 'GH-induced': [155, 353, 791, 933], 'stimulation': [156, 354, 776, 1568, 2315, 3696], 'ANGPTL4': [158, 192, 356, 390, 3202, 3312, 4169], 'seems': [161, 359], 'secondary': [162, 360, 3162], 'induction': [164, 362, 1620], 'This': [167, 365, 727, 1133, 1776, 3588], 'new': [168, 366, 3892, 4279], 'concept': [169, 367], 'implies': [170, 368], 'abundant': [172, 370], 'supply': [173, 371], 'circulating': [175, 373, 731, 3335], 'decreases': [177, 375], 'need': [179, 377], 'for': [180, 378, 740, 916, 1057, 1752, 2064, 2310, 2357, 2588, 2702, 2780, 2792, 2948, 2953, 2957, 2962, 3014, 3094, 3108, 3141, 3156, 3293, 3433, 4087], 'alternative': [181, 379], 'triglyceride-derived': [182, 380], 'through': [184, 382], 'distinct': [185, 383, 3981], 'inhibition': [186, 384, 833], 'mediated': [189, 387, 1633], 'increased': [191, 389, 452, 491, 707, 741, 1377, 3519, 3702, 3725], 'is': [399, 439, 641, 704, 830, 973, 1374, 1417, 1529, 1632, 1660, 1815, 2072, 2099, 2214, 3272, 4037], 'an': [400, 976, 1120, 1268, 1420, 1732, 1818, 1867, 1950, 1965, 1979, 1986, 1996, 2102, 2217, 2304, 2627, 3048, 3208, 3215, 3378, 3437, 3557], 'important': [401], 'regulator': [402], 'lipid': [404, 557, 742, 4072], 'metabolism': [405, 422, 743], 'skeletal': [407, 475, 1069, 1110, 1150, 1257, 1540, 1560, 1591, 1629, 1711, 1857, 1940, 2121, 2318, 2472, 3368, 3547], '(1M⊘ller': [409], 'N.': [410, 496, 801, 959, 961, 998, 1002, 1040, 1048, 1099, 1101, 1198, 1202, 1242, 1252, 1289, 1295, 1334, 1336, 1403, 1405, 1442, 1446, 1801, 1803, 1846, 1848, 1929, 1931, 2085, 2087, 2200, 2202, 2402, 2443, 3357, 3359, 3536, 3538], 'J⊘rgensen': [411, 497, 594, 698, 804, 966, 1005, 1043, 1102, 1205, 1296, 1323, 1410, 1449, 1808, 1849, 1932, 2092, 2207, 3360, 3539], 'J.O.': [412, 498, 595, 699, 805, 967, 1006, 1044, 1103, 1206, 1240, 1297, 1324, 1411, 1450, 1809, 1850, 1933, 2093, 2208, 3361, 3540], 'Effects': [413, 509], 'growth': [415, 512, 613, 812, 857, 917, 1024, 1224, 1310, 1341, 1353, 1379, 1468, 1514, 2425, 2750, 4075, 4242, 4321], 'on': [417, 515, 862, 1149, 1706, 1915, 2128, 2292, 2428, 2491, 2501, 2673, 2684, 2688, 2711, 3130, 3239, 3302, 3311, 3334], 'glucose,': [418, 3339], 'lipid,': [419], 'subjects.Endocr.': [425], 'Rev.': [426], '2009;': [427], '30:': [428], '152-177Crossref': [429], 'PubMed': [430, 528, 571, 628, 659, 722, 818, 874, 924, 988, 1034, 1083, 1128, 1234, 1279, 1316, 1367, 1432, 1478, 1523, 1597, 1646, 1830, 1875, 1958, 2114, 2229, 2394, 2437, 2480, 3386, 3565], 'Scopus': [431, 572, 629, 660, 723, 819, 875, 925, 989, 1035, 1084, 1129, 1235, 1280, 1317, 1368, 1433, 1479, 1524, 1598, 1647, 1831, 1876, 1959, 2115, 2230, 2395, 2438, 2481, 3387, 3566], '(670)': [432], 'Google': [433, 529, 574, 631, 662, 725, 821, 877, 927, 991, 1037, 1086, 1131, 1237, 1282, 1319, 1370, 1435, 1481, 1526, 1600, 1649, 1833, 1878, 1961, 2117, 2232, 2397, 2440, 2483, 3389, 3568], 'Scholar).': [434, 530, 575, 663, 726, 822, 928, 1132, 1371, 1482, 1650, 1879, 2118, 2233, 2484, 3390, 3569], 'secretion': [436], 'pulsatile': [440], 'pattern': [443], 'opposite': [444], 'suppressed': [448, 787, 3594, 3675], 'postprandial': [449], 'activity': [453, 581, 603, 911, 952], 'during': [454, 616, 794, 811, 2162, 2974, 3436, 3521, 3660, 3693, 4149], 'fasting': [455, 1339], 'exercise.': [457], 'Following': [458], 'exposure': [459, 1163, 1266], 'physiological': [462, 1656], 'intravenous': [463, 1269, 1733, 1966, 1980, 2305], 'bolus,': [465], 'distinctive': [466], 'temporal': [467], 'changes': [468, 3295, 3964, 4205], 'substrate': [470, 519, 1021, 1221, 1465, 4175], 'fluxes': [471, 520], 'are': [472, 535, 756, 779, 1394, 2352, 3261, 4049], 'muscle,': [476], 'characterized': [477, 3600], 'reversible': [479], 'glucose': [482, 773, 796, 1122, 1869, 1952, 1988, 3380, 3559], 'uptake': [483, 492, 774], 'peaks': [485], 'together': [489, 681], 'lipids': [494, 650], '(2M⊘ller': [495], 'Schmitz': [499, 1051, 1331], 'O.': [500, 1052, 1332], 'M⊘ller': [501, 800, 958, 1001, 1047, 1098, 1201, 1294, 1335, 1402, 1445, 1800, 1845, 1928, 2084, 2199, 3356, 3535], 'J.': [502, 504, 523, 715, 1076, 1272, 1500, 1510, 2369, 2387, 2406, 2410], 'Christiansen': [503, 592, 692, 802, 964, 1096, 1408, 1806, 1843, 1926, 2090, 2205, 3354, 3533], 'Alberti': [505], 'K.G.': [506], 'Ørskov': [507], 'H.': [508, 591], 'pulse': [514, 1705], 'total': [516, 2530, 2782], 'forearm': [518], 'humans.Am.': [522], 'Physiol.': [524, 716, 1077, 1273, 2388], '1990;': [525], '258:': [526], 'E86-E91Crossref': [527], 'Triglycerides': [531], '(TG)': [532], 'lipoproteins': [534], 'hydrolyzed': [536], 'lipoprotein': [540, 598], 'lipase': [541, 599, 602], '(LPL)': [542], 'entering': [544], 'cell': [547, 827, 1562], '(3Merkel': [548], 'M.': [549, 1091, 1612, 1838, 1921, 2367, 2449, 3349, 3528], 'Eckel': [550], 'R.H.': [551], 'Goldberg': [552], 'I.J.': [553], 'Lipoprotein': [554], 'lipase:': [555], 'genetics,': [556], 'uptake,': [558], 'regulation.J.': [560], 'Lipid': [561], 'Res.': [562, 870], '2002;': [563], '43:': [564], '1997-2006Abstract': [565], 'Full': [566, 568, 625, 656, 1641, 1643], 'Text': [567, 569, 626, 657, 1642, 1644], 'PDF': [570, 627, 658, 1645], '(451)': [573], 'Interestingly,': [576], 'treatment': [578, 615, 2427, 3994], 'downregulates': [579], '(4Richelsen': [582], 'B.': [583, 899, 2455], 'Pedersen': [584, 962, 999, 1094, 1199, 1243, 1325, 1406, 1443, 1804, 1841, 1924, 2088, 2203, 3352, 3531], 'S.B.': [585, 963, 1000, 1095, 1200, 1244, 1326, 1407, 1444, 1805, 1842, 1925, 2089, 2204, 3353, 3532], 'Kristensen': [586], 'K.': [587, 885, 2361, 2445], 'B⊘rglum': [588], 'J.D.': [589], 'N⊘rrelund': [590], 'J.S.': [593, 693, 803, 965, 1097, 1409, 1504, 1807, 1844, 1927, 2091, 2206, 3355, 3534], 'Regulation': [596], 'hormone-sensitive': [601], 'adipose': [608, 913, 1016, 1216, 1260, 1460], 'tissue': [611, 1261, 3940], 'weight': [617], 'loss': [618], 'obese': [620], 'patients.Metabolism.': [621], '2000;': [622], '49:': [623], '906-911Abstract': [624], '(68)': [630], 'Scholar),': [632, 1527], 'hypersecretion': [634], 'as': [637, 782, 946, 1168, 1170, 2327, 2843, 3229, 3263, 3599, 3654, 3874, 3928, 4199], 'seen': [638], 'acromegaly': [640], 'hypertriglyceridemia': [644], '(5Nikkila': [645], 'E.A.': [646], 'Pelkonen': [647], 'R.': [648, 1508], 'Serum': [649, 3201], 'acromegaly.Metabolism.': [652], '1975;': [653], '24:': [654], '829-838Abstract': [655], '(82)': [661], 'It': [664, 1153], 'has': [665, 1154, 1555], 'been': [666, 1156, 1556, 1793, 3344, 4144], 'shown': [667, 4145], 'humans': [669, 1301, 1659], 'turnover': [673], 'oxidation': [675], 'free': [677], 'fatty': [678], 'acids': [679], '(FFA)': [680], 'unaltered': [683, 712], 'VLDL-TG': [684, 735], 'kinetics': [685], '(6Krag': [686], 'M.B.': [687], 'Gormsen': [688, 995, 1195, 1247, 1286, 1327, 1439], 'L.C.': [689, 996, 1196, 1287, 1328, 1440], 'Guo': [690], 'Z.': [691], 'Jensen': [694, 1045], 'M.D.': [695], 'Nielsen': [696], 'S.': [697, 799, 1004, 1050, 1204, 1291, 1330, 1448], 'hormone-induced': [701], 'resistance': [703, 793, 935, 972, 1066, 1305, 1416, 1814, 2098, 2213, 4154], 'intramyocellular': [708], 'triglyceride': [709, 3685], 'content': [710], 'but': [711, 749, 3709], 'VLDL-triglyceride': [713], 'kinetics.Am.': [714], 'Endocrinol.': [717, 983, 1029, 1078, 1229, 1274, 1362, 1427, 1473, 1825, 2109, 2224, 2389, 2475], 'Metab.': [718, 984, 1030, 1079, 1230, 1275, 1363, 1428, 1474, 1519, 1826, 2110, 2225, 2390, 2476], '2007;': [719, 921, 1520, 2391], '292:': [720], 'E920-E927Crossref': [721], '(72)': [724], 'finding': [728], 'suggests': [729], 'rather': [733], 'than': [734], 'constitutes': [736], 'major': [738], 'source': [739], 'following': [746, 1114, 1265, 1861, 1944, 2534, 2868, 2942, 3372, 3551], 'stimulation,': [748, 3956], 'mechanisms': [751, 1137, 1512, 1684], 'regulate': [753], 'these': [754, 765, 2125, 3031], 'processes': [755], 'unknown.': [757, 1661], 'Experimental': [758], 'suggest': [763], 'insulin-antagonistic': [766], 'effects': [767, 1146, 1688, 1756, 2312, 2421], 'i.e.,': [770, 2175], 'FFA,': [778], 'causally': [780], 'linked,': [781], 'pharmacological': [783], 'antilipolysis': [784, 807], 'resulting': [785], 'abrogates': [790], 'clamp': [797, 2188, 3524, 3679], '(7Nielsen': [798], 'Pharmacological': [806], 'restores': [808], 'sensitivity': [810], 'exposure.Diabetes.': [814], '2001;': [815, 1594, 1638, 2434], '50:': [816], '2301-2308Crossref': [817], '(108)': [820], 'In': [823, 3391, 3456, 3511, 3570, 3639, 3668, 3682, 3718, 4167], 'animal': [824], 'models': [825], 'cultures,': [828], 'this': [829, 1373, 1553, 1694, 1716, 3736], 'IRS1-Akt': [836, 1141], '(8Dominici': [840], 'F.P.': [841], 'Argentino': [842], 'D.P.': [843], 'Munoz': [844], 'M.C.': [845], 'Miquet': [846], 'J.G.': [847], 'Sotelo': [848], 'A.I.': [849], 'Turyn': [850], 'D.': [851, 2453], 'Influence': [852], 'crosstalk': [855], 'between': [856, 3282], 'signalling': [861], 'modulation': [864], 'sensitivity.Growth': [867], 'Horm.': [868], 'IGF': [869], '2005;': [871, 1080], '15:': [872], '324-336Crossref': [873], '(130)': [876], 'Scholar)': [878, 1601], '(9del': [881], 'Rincon': [882], 'J.P.': [883], 'Iida': [884], 'Gaylinn': [886], 'B.D.': [887], 'McCurdy': [888], 'C.E.': [889], 'Leitner': [890], 'J.W.': [891], 'Barbour': [892], 'L.A.': [893], 'Kopchick': [894], 'J.J.': [895], 'Friedman': [896], 'J.E.': [897], 'Draznin': [898], 'Thorner': [900], 'M.O.': [901], 'regulation': [904, 1484, 1579, 2374, 2466], 'p85alpha': [906], 'phosphoinositide': [909], '3-kinase': [910, 1061], 'tissue:': [914, 1017, 1217, 1461], 'mechanism': [915], 'hormone-mediated': [918], 'resistance.Diabetes.': [920], '56:': [922], '1638-1646Crossref': [923], '(121)': [926], 'However,': [929, 1651], 'subjects,': [932], 'does': [936], 'not': [937, 3448, 3710, 4130], 'translate': [938], 'into': [939, 1175, 1546, 3979, 4032], 'pertinent': [942], 'pathways': [945], 'assessed': [947, 3287], 'western': [949], 'blotting': [950], 'assays': [953], '(10Krusenstjerna-Hafstr⊘m': [954, 1398, 1796, 2080, 2195], 'T.': [955, 1089, 1399, 1797, 1836, 1919, 2081, 2196, 3347, 3526], 'Clasen': [956, 1400, 1798, 2082, 2197], 'B.F.': [957, 1401, 1799, 2083, 2198], 'Jessen': [960, 997, 1100, 1197, 1241, 1288, 1333, 1404, 1441, 1802, 1847, 1930, 2086, 2201, 3358, 3537], '(GH)-induced': [970, 1414, 1812, 2096, 2211], 'rapidly': [974, 1418, 1816, 2100, 2215], 'reversible:': [975, 1419, 1817, 2101, 2216], 'experimental': [977, 1421, 1819, 2103, 2218], 'study': [978, 1422, 1695, 1777, 1820, 2070, 2104, 2141, 2219, 2244, 2270, 2383], 'GH-deficient': [980, 1424, 1822, 2106, 2221], 'adults.J.': [981, 1425, 1823, 2107, 2222], 'Clin.': [982, 1028, 1228, 1361, 1426, 1472, 1824, 2108, 2223, 2474], '2011;': [985, 1125, 1429, 1827, 1872, 1955, 2111, 2226, 3383, 3562], '96:': [986, 1430, 1828, 2112, 2227], '2548-2557Crossref': [987, 1431, 1829, 2113, 2228], '(38)': [990, 1434, 1832, 2116, 2231], 'Scholar,': [992, 1038, 1087, 1238, 1283, 1320, 1436, 1834, 2398, 2441], '11Nielsen': [993, 1437], 'C.': [994, 1194, 1438, 2459], 'Lund': [1003, 1049, 1203, 1249, 1290, 1329, 1447], 'impact': [1018, 1118, 1218, 1462, 1700, 1865, 1948, 3376, 3555], 'insulin,': [1020, 1220, 1464], 'background,': [1022, 1222, 1466], 'receptor': [1026, 1180, 1226, 1254, 1470], 'blockade.J.': [1027, 1227, 1471], '2008;': [1031, 1231, 1313, 1475], '93:': [1032, 1232, 1476], '2842-2850Crossref': [1033, 1233, 1477], '(56)': [1036, 1236, 1480], '12Jessen': [1039], 'Djurhuus': [1041], 'C.B.': [1042], 'L.S.': [1046], 'Evidence': [1053], 'against': [1054], 'role': [1056], 'insulin-signaling': [1058], 'proteins': [1059, 3166], 'PI': [1060], 'Akt': [1063], 'induced': [1071, 3399, 3574, 3613, 3645, 4148], 'short-term': [1073], 'infusion.Am.': [1075], '288:': [1081], 'E194-E199Crossref': [1082], '(58)': [1085], '13Krusenstjerna-Hafstr⊘m': [1088, 1835], 'Madsen': [1090, 1837, 1920, 3348, 3527], 'Vendelbo': [1092, 1839, 1922, 3350, 3529], 'M.H.': [1093, 1322, 1840, 1923, 3351, 3530], 'Insulin': [1104, 1619, 1851, 1934, 3362, 3541], 'exogenous': [1115, 1171, 1862, 1945, 3373, 3552], 'exposure:': [1117, 1864, 1947, 3375, 3554], 'oral': [1121, 1868, 1951, 1987, 2262, 3379, 3558], 'load.PLoS': [1123, 1870, 1953, 3381, 3560], 'ONE.': [1124, 1871, 1954, 3382, 3561], '6:': [1126, 1873, 1956, 3384, 3563], 'e19392Crossref': [1127, 1874, 1957, 3385, 3564], '(22)': [1130, 1877, 1960, 3388, 3567], 'indicates': [1134], 'additional': [1136], 'apart': [1138], 'from': [1139, 1781, 1785, 2001, 2124, 2295, 2497, 2507, 2510, 3846, 3900], 'mediate': [1144], 'metabolism.': [1152, 4059], 'also': [1155, 2182], 'systemic': [1162], 'endogenous': [1167], 'well': [1169], 'origin': [1172], 'translates': [1174], 'detectable': [1176, 3451], 'terms': [1185], 'tyrosine-phosphorylation': [1187], 'transcription': [1190], 'factor': [1191, 1380, 4322], 'STAT5': [1192, 1396], '(11Nielsen': [1193], '14J⊘rgensen': [1239], 'Vestergaard': [1245], 'E.': [1246], 'L.': [1248], 'S.A.': [1250], 'Billestrup': [1251], 'bolus.Am.': [1271], '2006;': [1276], '291:': [1277], 'E899-E905Crossref': [1278], '(71)': [1281], '15Vestergaard': [1284], 'E.T.': [1285], 'Hansen': [1292], 'T.K.': [1293], 'Ghrelin': [1298], 'infusion': [1299, 2166, 3460, 3642, 3662], 'induces': [1302], 'acute': [1303, 1653, 1687, 2311], 'independent': [1308, 3739], 'signaling.Diabetes.': [1312], '57:': [1314], '3205-3210Crossref': [1315], '(126)': [1318], '16Vendelbo': [1321], 'Exercise': [1337], 'activate': [1340], 'hormone-dependent': [1342], 'myocellular': [1343], 'signal': [1344], 'transducer': [1345], 'activator': [1347], 'transcription-5b': [1349], 'phosphorylation': [1350], 'insulin-like': [1352, 1378], 'factor-I': [1354], 'messenger': [1355], 'ribonucleic': [1356], 'acid': [1357, 4058, 4068, 4253, 4288], 'humans.J.': [1360], '2010;': [1364], '95:': [1365], 'E64-E68Crossref': [1366], '(24)': [1369], 'Moreover,': [1372], 'followed': [1375, 2654], '1': [1381, 1881, 2297, 2499, 3157, 3398, 3848, 3902], '(IGF-1)': [1382], 'suppressor': [1384, 1583], 'cytokine': [1386, 1585, 2889], '(SOCS)': [1388], 'expression,': [1390, 4054], 'both': [1391, 3512, 3669, 3690, 3705], 'known': [1395], 'targets': [1397], 'Because': [1483], 'mediates': [1488], 'numerous': [1489], 'actions': [1490], '(17Cesena': [1493], 'T.I.': [1494], 'Cui': [1495], 'T.X.': [1496], 'Piwien-Pilipuk': [1497], 'G.': [1498, 2414], 'Kaplani': [1499], 'Calinescu': [1501], 'A.A.': [1502], 'Huo': [1503], 'Iniguez-Lluhi': [1505], 'J.A.': [1506], 'Kwok': [1507], 'Schwartz': [1509], 'Multiple': [1511], 'hormone-regulated': [1515], 'transcription.Mol.': [1517], 'Genet.': [1518], '90:': [1521], '126-133Crossref': [1522], '(45)': [1525], 'it': [1528], 'likely': [1530], 'identification': [1532], 'may': [1542], 'provide': [1543], 'novel': [1544], 'insight': [1545], 'metabolic': [1548, 2376], 'responses': [1549], 'described': [1550, 2073, 2844, 3230], 'above.': [1551], 'Indeed,': [1552], 'approach': [1554], 'used': [1557, 2120, 3013, 3310], 'murine': [1559], 'lines': [1563], 'vitro': [1565], 'alone': [1569, 3446, 3612, 3691], '(18Sadowski': [1570], 'C.L.': [1571, 1608], 'Wheeler': [1572, 1613], 'T.T.': [1573, 1614], 'Wang': [1574, 1615], 'L.H.': [1575, 1616], 'Sadowski': [1576, 1617], 'H.B.': [1577, 1618], 'IGF-I': [1581], 'C2C12': [1590, 1628, 2724], 'cells.Endocrinology.': [1593], '142:': [1595, 2435], '3890-3900Crossref': [1596], '(69)': [1599], 'combination': [1604, 1770, 1984], '(19Sadowski': [1607], 'Choi': [1609], 'T.S.': [1610], 'Le': [1611], 'SOCS-2': [1622], 'SOCS-3': [1624], 'mRNA': [1625, 2493, 2503, 4002], 'cells': [1631, 2725, 2746, 2820], 'Stat5*.J.': [1635], 'Biol.': [1636], 'Chem.': [1637], '276:': [1639], '20703-20710Abstract': [1640], '(59)': [1648], 'response': [1654, 2346], 'under': [1655, 3030], 'conditions': [1657], 'DNA': [1663], 'microarray': [1664, 2382, 4000], 'technology': [1665, 1737], 'measures': [1666, 3307], 'large': [1671], 'numbers': [1672], 'simultaneously,': [1675], 'provides': [1677], 'means': [1679, 3264, 3875, 3929, 4200], 'disentangle': [1681], 'transcriptional': [1683], 'underlying': [1685], 'aim': [1692], 'identify': [1698], 'single': [1703], 'vivo.': [1714], 'To': [1715, 1750, 3997], 'end,': [1717], 'eight': [1718, 1884, 2029], 'healthy': [1719, 1885], 'male': [1720], 'underwent': [1722, 2183], 'used,': [1739], 'functional': [1741], 'classification': [1742], 'GH-responsive': [1744], 'qRT-PCR': [1748, 4015, 4190], 'verification.': [1749], 'test': [1751, 2309], 'direct': [1753], 'indirect': [1755], 'investigated': [1764], 'when': [1765, 2176, 3267, 3274, 3631], 'given': [1768], 'insulin-induced': [1772], 'presents': [1778], 'two': [1782, 2129, 3980], 'clinical': [1783], 'studies': [1784, 2359], 'different': [1790], 'nature': [1791], 'have': [1792, 3342, 4143], 'published': [1794, 2356, 3345], 'previously': [1795, 3343], 'Group': [1880, 2025], 'consisted': [1882, 2027], 'men': [1886], 'ages': [1887, 2035], '24.6': [1888], '±': [1889, 1893, 1904, 2037, 2041, 2048, 3265, 3406, 3410, 3441, 3467, 3482, 3486, 3748, 3750, 3761, 3763, 3773, 3775, 3777, 3779, 3791, 3793, 3804, 3806, 3809, 3811, 3813, 3815, 3825, 3827, 3829, 3831, 3876, 3930, 4201], '1.8': [1890], 'years': [1891, 2039], '(mean': [1892, 2040, 3409, 3485], 'SE)': [1894, 2042], 'mean': [1897, 3478], 'body': [1898], 'mass': [1899], 'index': [1900], '(BMI)': [1901], '24.2': [1903], '1.2': [1905], 'kg*m−2': [1906], 'who': [1907, 2051], 'studied': [1909], 'randomized,': [1912], 'crossover': [1913], 'design': [1914, 2071], 'occasions': [1917], '(13Krusenstjerna-Hafstr⊘m': [1918, 3346, 3525], 'Scholar):': [1962], '1)': [1963], 'bolus': [1968, 1982, 2307, 3395], '(0.5': [1969, 2815], 'mg': [1970], 'Genotropin,': [1971], 'Miniquick,': [1972], 'Pfizer,': [1973], 'New': [1974], 'York,': [1975], 'NY),': [1976], '2)': [1977], 'load': [1989], '(OGTT)': [1990], '(75': [1991], 'g),': [1992], '3)': [1994], 'OGTT': [1997, 3438, 3445, 3611, 3633, 3689, 3708, 3714], 'alone.': [1998], 'Muscle': [1999], 'vastus': [2002], 'lateralis': [2003], 'collected': [2005, 2824], 'at': [2006, 2020, 2065, 2135, 2192, 2238, 2544, 2564, 2946, 3097, 3105, 3111, 3424, 3470], 't': [2007, 2012, 3425, 3471, 3495], '=': [2008, 2013, 3426, 3472, 3496, 3637, 3652, 3664, 3851, 3856, 3863, 3868, 3905, 3910, 3917, 3922], '0': [2009, 3473], 'min': [2010, 2302, 3096, 3110, 3584, 3607, 3727, 3944], '120': [2014, 2301, 3427, 3583, 3606, 3943], 'min.': [2015, 2024, 3428, 3498], 'Blood': [2016, 2234], 'drawn': [2019, 2237], 'least': [2021, 2066, 2136, 2239, 2565], 'every': [2022, 2240, 2777], '30': [2023], 'patients': [2030, 2126, 2181, 2509], 'deficiency': [2033], '(GHD)': [2034], '57.0': [2036], '2.5': [2038], 'BMI': [2045], '30.6': [2047], '1.4': [2049], 'kg*m−2,': [2050], 'treated': [2053], 'stable': [2055], 'doses': [2056], 'other': [2060, 3989], 'pituitary': [2061], 'substitution': [2062], 'therapy': [2063], 'months.': [2068], 'detail': [2075], 'previous': [2078], 'publication': [2079], 'taken': [2127, 2147, 2161, 3991], 'separate': [2130, 2155], 'examination': [2131, 2173], 'days,': [2132], 'separated': [2133], 'four': [2137, 4114], 'weeks.': [2138], 'On': [2139, 2153, 2171], 'one': [2140, 2944, 3983], 'day,': [2142, 2156, 2174], 'biopsy': [2145, 2159], 'discontinuation': [2149], 'therapy.': [2152], 'low-dose': [2164], 'commenced': [2167], '6.5': [2168], 'earlier.': [2170], 'each': [2172], 'taken,': [2180], '6': [2185], 'hyperinsulinemic-euglycemic': [2187], 'infused': [2191], '0.5': [2193, 3077], 'mU/kg/min': [2194], 'h.': [2242], 'Both': [2243], 'protocols': [2245], 'approved': [2247], 'Regional': [2250], 'Scientific': [2251], 'Ethics': [2252], 'Committee': [2253], 'Denmark': [2255], '(M-20070052;': [2256], 'M-20070176),': [2257], 'all': [2259, 2589, 2665], 'participants': [2260], 'gave': [2261], 'written': [2264], 'informed': [2265], 'consent': [2266], 'participate.': [2268], 'conducted': [2272, 2833], 'accordance': [2274], 'Helsinki': [2277], 'Declaration.': [2278], 'performed': [2280, 2636, 2672, 2682, 2710, 2917, 3228, 3301, 3319, 3326, 4269], 'Human': [2281, 2618], 'Gene': [2282, 2619], '1.0': [2283, 2620], 'ST': [2284, 2621], 'Array': [2285, 2622], '(Affymetrix': [2286], 'Inc.,': [2287, 2524, 2863, 2928], 'Santa': [2288, 2578], 'Clara,': [2289, 2579], 'CA)': [2290, 2605], 'analysis': [2291, 2416, 2634, 2670, 2708, 3299, 3324, 4098, 4108], 'group': [2296, 2498, 2511, 3397, 3457, 3571, 3640, 3683, 3719, 3847, 3859, 3901, 3913, 4029], '(study': [2320], 'day': [2321, 2779], '1).': [2322, 3698], 'Regulated': [2323, 4018], 'displaying': [2330], 'fold': [2332, 3294, 4204], 'change': [2333, 3503], '≤': [2335, 3276, 4219], '0.7': [2336], 'or': [2337, 3732, 3962], '≥': [2338], '1.4,': [2339], 'P-value': [2342], '<': [2343, 3413, 3489, 3586, 3609, 3621, 3753, 3765, 3781, 3796, 3817, 3833, 3880, 3969], '0.05': [2344, 3754, 3766, 3782, 3797, 3818, 3834, 3881, 4220], 'treatment.': [2349, 3871, 3887, 3925], 'These': [2350], 'criteria': [2351], 'similar': [2353, 2358, 3010, 3630], 'those': [2355], '(20Sjögren': [2360], 'Leung': [2362], 'K.C.': [2363], 'Kaplan': [2364], 'W.': [2365], 'Gardiner-Garden': [2366], 'Gibney': [2368], 'Ho': [2370], 'K.K.': [2371], 'muscle:': [2380], 'hypopituitary': [2385], 'men.Am.': [2386], '293:': [2392], 'E364-E371Crossref': [2393], '(46)': [2396], '21Flores-Morales': [2399], 'A.': [2400, 2451], 'Stahlberg': [2401], 'Tollet-Egnell': [2403], 'P.': [2404, 2447], 'Lundeberg': [2405], 'Malek': [2407], 'R.L.': [2408], 'Quackenbush': [2409], 'Lee': [2411], 'N.H.': [2412], 'Norstedt': [2413], 'hypophysectomy': [2423], 'rat.Endocrinology.': [2433], '3163-3176Crossref': [2436], '(88)': [2439], '22Viguerie': [2442], 'Clement': [2444], 'Barbe': [2446], 'Courtine': [2448], 'Benis': [2450], 'Larrouy': [2452], 'Hanczar': [2454], 'Pelloux': [2456], 'V.': [2457], 'Poitou': [2458], 'Khalfallah': [2460], 'Y.': [2461], 'et': [2462], 'al.In': [2463], 'epinephrine-mediated': [2465], 'muscle.J.': [2473], '2004;': [2477], '89:': [2478], '2000-2014Crossref': [2479], '(52)': [2482], 'Expression': [2485, 2601], 'level': [2494], 'GHD': [2508], '2.': [2512], 'Skeletal': [2513], 'powder': [2515], 'homogenized': [2518, 3046], 'TriZol': [2520], 'reagent': [2521], '(Life': [2522], 'Technologies': [2523], 'Life': [2525], 'Technologies,': [2526, 3039], 'Roskilde,': [2527], 'Denmark),': [2528], 'RNA': [2531, 2538, 2571, 2592], 'extracted': [2533], "manufacturer's": [2536, 2609, 3233], 'protocol.': [2537, 3234], 'quantified': [2540, 3183, 3192], 'measuring': [2542], 'absorbance': [2543], '260': [2545], '280': [2547], 'nm': [2548], 'using': [2549, 2574, 2626, 2676, 2715, 2839, 2920, 2940, 2984, 3118, 3173, 3184, 3198, 3256, 3320], 'NanoDrop': [2551], '8000': [2552], '(NanoDrop': [2553], 'Products,': [2554], 'Wilmington,': [2555], 'DE);': [2556], 'inclusion': [2558], 'criterion': [2559], 'ratio': [2562], '1.8.': [2566], 'integrity': [2568], 'determined': [2573, 3117, 3204], 'Bioanalyzer': [2575], '2100': [2576], '(Agilent,': [2577], 'CA).': [2580], 'RIN': [2582], 'score': [2583], '>': [2584], '7': [2585], 'samples.': [2590, 4214], 'Total': [2591, 3113, 3189, 3248, 3699], '(100': [2593], 'ng)': [2594], 'labeled': [2596], 'Ambion': [2599], 'WT': [2600], 'Kit': [2602, 2925], '(Ambion,': [2603], 'Carlsbad,': [2604], 'according': [2606], 'instructions.': [2610], 'Samples': [2611, 3091], 'hybridized': [2613], 'overnight': [2614], 'GeneChip': [2617], '(Affymetrix)': [2623], 'scanned': [2625], 'Affymetrix': [2628], 'GCS': [2629], '3000': [2630], '7G': [2631], 'scanner.': [2632], 'Data': [2633, 3260, 3333, 3872, 3926, 4197], 'GeneSpring': [2639], 'GX11.5': [2640], 'software': [2641, 2993], '(Agilent).': [2642], 'Cel': [2643], 'files': [2644], 'imported': [2646], 'quantile': [2648], 'normalized': [2649], 'iterPLIER16': [2652], 'algorithm': [2653], 'baseline': [2656, 3985, 4213], 'transformation': [2657], 'median': [2659, 2663], 'scaling': [2660], 'arrays.': [2666], 'Differential': [2667], 'transcript': [2674], 'values': [2675], 'paired': [2677, 3289, 4216], 't-test.': [2678, 3290], 'Hierarchical': [2679, 3971], 'clustering': [2680, 3972], 'vertically': [2683], 'horizontally': [2687], 'Euclidian': [2691], 'distance': [2692], 'centroid': [2694], 'linkage': [2695], '(default': [2696], 'GeneSpring).': [2698], 'DAVID': [2700, 4097], '(Database': [2701], 'Annotation,': [2703], 'Visualization': [2704], 'Integrated': [2706], 'Discovery)': [2707], 'available': [2717], 'online': [2718], 'tool': [2719, 4027], '(DAVID': [2720], 'Bioinformatics': [2721], 'Resources': [2722], 'v6.7).': [2723], '(ATCC,': [2726], 'Manassas,': [2727], 'VA)': [2728], 'cultured': [2730], 'DMEM': [2732, 2759], '(1': [2733, 2760], 'g/l': [2734, 2761], 'glucose),': [2735, 2762], '10%': [2736], 'FBS,': [2737], '100': [2738, 2742, 2766, 2770], 'U/ml': [2739, 2767], 'penicillin,': [2740, 2768], 'μg/ml': [2743, 2771], 'streptomycin.': [2744, 2772], 'When': [2745, 3291], 'reached': [2747], 'confluency,': [2748], 'medium': [2751, 2756, 2774, 2791], 'substituted': [2753], 'differentiation': [2755], 'consisting': [2757], '2%': [2763], 'horse': [2764], 'serum,': [2765], 'Differentiation': [2773], 'changed': [2776], 'second': [2778], 'seven': [2784], 'days.': [2785], 'Cells': [2786], 'starved': [2788], 'serum-free': [2790], 'prior': [2795], 'incubation': [2800], 'either': [2802], 'palmitate': [2803], '[0.5': [2804], 'mM,': [2805], 'conjugated': [2806], '1%': [2808, 3067], '(w/v)': [2809], 'FFA-free': [2810], 'BSA': [2811], '(Sigma))': [2812], 'and/or': [2813], 'µg/ml,': [2816], 'Genotropin],': [2817], 'harvested': [2822], 'scraping': [2826], 'cold': [2828], 'PBS.': [2829], 'All': [2830, 3003], 'experiments': [2831], 'duplicate.': [2835, 3008], 'cDNA': [2836, 2849], 'constructed': [2838], 'random': [2840], 'hexamer': [2841], 'primers': [2842], 'manufacturer': [2847], '(Verso': [2848], 'kit;': [2850], 'Abgene,': [2851], 'Epsom,': [2852], 'UK).': [2853], 'Then': [2854], 'KAPA': [2855, 2921], 'SYBR': [2856], 'FAST': [2857, 2923], 'qPCR': [2858, 2924], 'Master': [2859], 'Mix': [2860], '(Kapa': [2861, 2926], 'Biosystems': [2862, 2927], 'Woburn,': [2864, 2929], 'MA)': [2865, 2930], 'primer': [2869], 'pairs': [2870], 'added:': [2872], 'SOCS-1,': [2873], '5′-ACACGCACTTCCGCACATTC-3′': [2874], '5′-CGAGGCCATCTTCACGCTAAG-3′;': [2876], 'SOCS-2,': [2877], '5′-GGTCGAGGCGATCAGTG-3′': [2878], '5′-TCCTTGAAGTCAGTGCGAATC-3′;': [2880], 'SOCS-3,': [2881], '5′-GCCCTTTGCGCCCTTT-3′': [2882], '5′-CGGCCACCTGGACTCCTATGA-3′;': [2884], 'IGF-1,': [2885], '5′-GACAGGGGCTTTATTTCAAC-3′': [2886], '5′-CTCCAGCCTCCTTAGATCAC-3′;': [2888], 'inducible': [2890], 'SH2-containing': [2891], '(CISH),': [2893], '5′-GCCCTGAGCCCTGGTAGTCC-3′': [2894], '3′-GACACATTCACAGACGGGTGG-5′;': [2896], 'angiopoietin-related': [2897], 'protein-like': [2898], '4': [2899, 3086], '(ANGPTL4),': [2900], '5′-': [2901], 'TAGTCCACTCTGCCTCTCCC-3′': [2902], '3′-GAGATGGCCCAGCCAGTT-5′;': [2904], 'β2-microglobulin,': [2905], '5′-AATGTCGGATGGATGAAACC-3′': [2906], '5′-TCTCTCTTTCTGGCCTGGAG-3′;': [2908], 'β-actin,': [2909], '5′-ACGGGGTCACCCACACTGTGC-3′': [2910], '3′CTAGAAGCATTTGCGGTGGACGATG-5′.': [2912], 'PCR': [2914, 3026], 'reactions': [2915], 'duplicate': [2919, 3206], 'SYBR®': [2922], 'LightCycler': [2933], '480': [2934, 2996], '(Roche': [2935, 2998], 'Applied': [2936, 2999], 'Science,': [2937, 3000], 'Penzberg,': [2938, 3001], 'Germany)': [2939], 'protocol:': [2943], 'step': [2945], '95°C': [2947, 2952], '3': [2949, 4061], 'min.,': [2950], '10': [2954, 2963], 's,': [2955, 2959], '60°C': [2956], '20': [2958, 3052, 3095, 3109], '72°C': [2961], 's': [2964], 'increase': [2966, 3475, 3577, 3648], 'fluorescence': [2968], 'measured': [2970, 3255, 3843, 3897], 'real': [2972], 'time': [2973, 3493], 'extension': [2976], 'step.': [2977], 'relative': [2979, 4211], 'estimated': [2983], 'default': [2986], '"Advanced': [2987], 'Relative': [2988], 'Quantification"': [2989], 'mode': [2990], 'version': [2994], 'LCS': [2995], '1.5.0.39': [2997], 'Germany).': [3002], 'amplified': [3006], 'setup': [3011], 'negative': [3015], 'controls,': [3016], 'except': [3017], 'reverse': [3020], 'transcriptase': [3021], 'omitted': [3023], 'products': [3027], 'detected': [3029], 'conditions.': [3032], 'Using': [3033], 'Precellys': [3035], '24': [3036], 'homogenizer': [3037], '(Bertin': [3038], 'Montigny-le-Bretonneux,': [3040], 'France),': [3041], 'ice-cold': [3049], 'buffer': [3050], 'containing': [3051, 3984], 'mM': [3053, 3056, 3059, 3062, 3065, 3072, 3075, 3078], 'Tris,': [3054], '50': [3055, 3058, 3080], 'NaCl,': [3057], 'NaF,': [3060], '5': [3061], 'Na4P2O7,': [3063], '250': [3064], 'sucrose,': [3066], '(v/v)': [3068], 'Triton': [3069], 'X-100,': [3070], 'DTT,': [3073], '0.1': [3074], 'benzamidine,': [3076], 'PMSF,': [3079], 'µg/ml': [3081, 3087], 'soybean': [3082], 'trypsin': [3083], 'inhibitor,': [3084], 'leupeptin': [3088], '(pH': [3089], '7.4).': [3090], 'rotated': [3093], '4°C.': [3098, 3112], 'Insoluble': [3099], 'materials': [3100], 'removed': [3102], 'centrifugation': [3104], '14,000': [3106], 'g': [3107], 'concentrations': [3115], 'Bradford': [3119], 'assay': [3121, 3210, 3226], '(Bio-Rad),': [3122, 3135], 'resolved': [3127], 'SDS-PAGE': [3129], 'precast': [3131], 'StainFree': [3132, 3196], '4–15%': [3133], 'gels': [3134], 'transferred': [3136], 'onto': [3137], 'PVDF': [3138], 'membranes,': [3139], 'blocked': [3140], '0.3%': [3145], 'iBlock,': [3146], 'incubated': [3147, 3155], 'anti-CISH': [3149], 'antibodies': [3150], '(ab88383,': [3151], 'Abcam,': [3152], 'Cambridge,': [3153], 'MA),': [3154], 'appropriate': [3160], 'HRP-conjugated': [3161], 'AB,': [3163], 'interest': [3168], 'visualized': [3170], 'ECL': [3172], 'ChemiDoc': [3175], 'XRS': [3176], 'system': [3177], '(Bio-Rad).': [3178], 'Specific': [3179], 'signals': [3181], 'Image': [3185, 3199, 4224], 'Lab': [3186], '(v4.0.1,': [3187], 'Bio-Rad).': [3188], 'Bio-Rad': [3195], 'technique': [3197], 'Lab.': [3200], 'ELISA': [3209], '(RayBiotech,': [3211], 'Norcross,': [3212], 'GA)': [3213], 'intra-': [3216], 'interassay': [3218], 'CV': [3219], '6%': [3221], '10%,': [3223], 'respectively.': [3224], 'Qualitative': [3235], 'readings': [3236], 'done': [3238], 'Victor3': [3241], '1420': [3242], 'Multilabel': [3243], 'Counter': [3244], '(PerkinElmer,': [3245], 'Waltham,': [3246], 'MA).': [3247], 'cholesterol': [3249, 3700, 3721, 3842, 3896], 'triglycerides': [3251, 3744], 'standard': [3257], 'enzymatic': [3258], 'kits.': [3259], 'presented': [3262, 3873, 3927, 4198], 'SE': [3266, 4202], 'normally': [3268, 3283], 'distributed,': [3269], 'significance': [3271], 'assumed': [3273], 'P': [3275, 3412, 3488, 3879, 3968, 4259], '0.05.': [3277, 3970], 'Statistical': [3278], 'evaluation': [3279], 'differences': [3281], 'distributed': [3284], 'testing': [3292], 'mRNA,': [3297], 'statistical': [3298], 'log-transformed': [3303], 'data.': [3304, 3315], 'Two-way': [3305], 'repeated': [3306], 'ANOVA': [3308], 'Posthoc': [3316], 'tests': [3317], 'Student-Newman-Keuls': [3321], 'test.': [3322], 'Correlation': [3323], "Person's": [3328], 'Product': [3329], 'Moment': [3330], 'correlation': [3331], 'analysis.': [3332, 3953], 'hormones': [3336], '(GH,': [3337], 'insulin),': [3338], 'short,': [3392], 'peak': [3403], '80.3': [3405], '6.4': [3407], 'µg/l': [3408, 3423, 3469, 3484], 'SE,': [3411, 3487], '0.001),': [3414], 'had': [3416], 'returned': [3417], 'basal': [3419], '∼1.5': [3422], 'same': [3430], 'observed': [3432], 'administered': [3435], '(GHt=10=': [3439], '78.5': [3440], '3.8': [3442], 'µg/l),': [3443], 'whereas': [3444, 4127], 'excursions': [3453], '(Fig.': [3454, 3509, 3666, 3680, 3995, 4016], '1A).': [3455], '2,': [3458, 3641, 3720, 4041, 4291, 4300, 4313], 'caused': [3461], '0.09': [3466], '0.03': [3468], 'value': [3479, 4260], '2.41': [3481], '0.24': [3483], '0.001)': [3490], 'interval': [3494], '120–420': [3497], 'During': [3499], 'saline': [3500, 3516, 3661, 3733], 'infusion,': [3501, 3517, 3734], '1B).': [3510], '5-fold': [3520], 'hyperinsulinemic': [3523, 3678], '1,': [3572, 3684], '∼75%': [3576], '(P': [3585, 3608, 3620, 3636, 3651, 3663], '0.001).': [3587, 3610, 3622], 'lipolytic': [3589], 'effect': [3590, 3737], 'OGTT,': [3598], '∼85%': [3603], 'decrease': [3615], '∼90%': [3619], 'degree': [3624], '(AUCFFA)': [3628], 'comparing': [3632], 'OGTT+GH': [3635], '0.083).': [3638], '∼45%': [3647], '0.04),': [3653], 'opposed': [3655], '∼18%': [3658], '0.01)': [3665], '1C).': [3667], 'situations,': [3670], 'almost': [3673], 'completely': [3674], '1D).': [3681], 'decreased': [3687], '(Table': [3697], '∼4%': [3703], 'combined': [3713], 'stimulation.': [3717], 'slightly': [3724], '360': [3726], 'initiation': [3729], 'stimulation.TABLE': [3742], '1Serum': [3743], 'cholesterolTriglyceridesCholesterolTreatmentBeforeAfterBeforeAfterGroup': [3746], '1Glucose0.89': [3747], '0.180.79': [3749], '0.19': [3751], '*P': [3752, 3795, 4218], 'compared': [3755, 3767, 3783, 3798, 3819, 3835, 3882], 'treatment.3.50': [3760], '0.373.61': [3762], '0.41*P': [3764], 'treatment.GH0.83': [3772], '0.440.84': [3774], '0.233.65': [3776], '0.673.81': [3778], '0.66*P': [3780], 'treatment.GH': [3788], '+': [3789], 'glucose0.80': [3790], '0.150.66': [3792], '0.14': [3794], 'treatment.3.66': [3803], '0.413.69': [3805], '0.40Group': [3807], '2Saline1.03': [3808], '0.301.09': [3810], '0.383.91': [3812], '0.854.25': [3814], '0.91*P': [3816], 'treatment.GH1.21': [3824], '0.441.28': [3826], '0.323.90': [3828], '0.944.24': [3830], '0.77*P': [3832], 'treatment.Triglyceride': [3840], '(t': [3850, 3855, 3862, 3867, 3904, 3909, 3916, 3921], '0)': [3852, 3864, 3906, 3918], '120)': [3857, 3911], '360)': [3869, 3923], 'indicated': [3870, 3924], 'SD': [3877, 3931], '[mM].*': [3878], 'Open': [3888, 4275], 'table': [3889, 4276], 'tab': [3893, 4280], 'Triglyceride': [3894], '[mM].': [3932], 'Genes': [3933], 'differentially': [3936], 'expressed': [3937], 'array': [3952, 4093], 'After': [3954], 'satisfied': [3959], '0.7-': [3961], '1.4-fold': [3963], 'performed,': [3974], 'fell': [3978], 'clusters,': [3982], '2).': [3996], 'verify': [3998], 'data,': [4001], 'six': [4005], '(IGF-1,': [4007], 'SOCS1–3,': [4008, 4162], 'ANGPTL4)': [4011], 'confirmed': [4013], '3).': [4017], 'analyzed': [4021], 'Ingenuity': [4024, 4104, 4107, 4271], 'Pathway': [4025, 4105, 4272], 'Analysis': [4026, 4268, 4273], 'biological': [4033, 4046], 'functions.': [4034], 'result': [4036], 'depicted': [4038], 'Table': [4040, 4060], 'main': [4045], 'functions': [4047], 'growth,': [4050], 'proliferation,': [4051, 4077], 'differentiation,': [4052], 'movement,': [4055], 'amino': [4057, 4067], 'lists': [4062], 'metabolism,': [4069, 4071, 4073, 4176], 'carbohydrate': [4070], 'cellular': [4074, 4235], 'expression.': [4080], 'See': [4081], 'supplementary': [4082], 'Tables': [4083], 'I': [4084], 'II': [4086], 'complete': [4089], 'list': [4090], 'supporting': [4099], 'findings': [4101], 'Analysis.': [4106], 'revealed': [4112], 'genes,': [4115], 'regulated,': [4126], 'IGF-1': [4128], 'found': [4131], 'be': [4133, 4147], 'within': [4135], 'window.': [4139], 'Six': 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