Publication Information

{'id': 'https://openalex.org/W2314049273', 'doi': 'https://doi.org/10.1016/j.juro.2016.02.2496', 'title': 'MP13-15 MOLECULAR URINE CYTOLOGY – BLADDER EPICHECK IS A NOVEL MOLECULAR DIAGNOSTIC TOOL FOR MONITORING OF BLADDER CANCER PATIENTS', 'display_name': 'MP13-15 MOLECULAR URINE CYTOLOGY – BLADDER EPICHECK IS A NOVEL MOLECULAR DIAGNOSTIC TOOL FOR MONITORING OF BLADDER CANCER PATIENTS', 'publication_year': 2016, 'publication_date': '2016-03-28', 'ids': {'openalex': 'https://openalex.org/W2314049273', 'doi': 'https://doi.org/10.1016/j.juro.2016.02.2496', 'mag': '2314049273'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2016.02.2496', 'pdf_url': 'https://www.auajournals.org/doi/pdf/10.1016/j.juro.2016.02.2496', 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.auajournals.org/doi/pdf/10.1016/j.juro.2016.02.2496', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042585436', 'display_name': 'Adam Wasserstrom', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Adam Wasserstrom', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022521962', 'display_name': 'Danny Frumkin', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Danny Frumkin', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067878298', 'display_name': 'Zohar Dotan', 'orcid': 'https://orcid.org/0000-0002-9005-2992'}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Zohar Dotan', 'raw_affiliation_strings': ['Tel-Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Tel-Aviv, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013855129', 'display_name': 'Elena Bukin', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Elena Bukin', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010452934', 'display_name': 'Tal Gadish', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Tal Gadish', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033402036', 'display_name': 'Shiri Hanuka', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Shiri Hanuka', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085956551', 'display_name': 'Revital Knirsh', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Revital Knirsh', 'raw_affiliation_strings': ['Rehovot, Israel'], 'affiliations': [{'raw_affiliation_string': 'Rehovot, Israel', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048499998', 'display_name': 'Abd Elhalim Darawsha', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Abd Elhalim Darawsha', 'raw_affiliation_strings': ['Tel-Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Tel-Aviv, Israel', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082120708', 'display_name': 'Ilan Leibovitch', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Ilan Leibovitch', 'raw_affiliation_strings': ['Tel-Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Tel-Aviv, Israel', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.882, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 23, 'citation_normalized_percentile': {'value': 0.857776, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '195', 'issue': '4S', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9702, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12695', 'display_name': 'Urinary and Genital Oncology Studies', 'score': 0.9556, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/urine-cytology', 'display_name': 'Urine cytology', 'score': 0.5212848}], 'concepts': [{'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.89506817}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7781273}, {'id': 'https://openalex.org/C2780026642', 'wikidata': 'https://www.wikidata.org/wiki/Q40924', 'display_name': 'Urine', 'level': 2, 'score': 0.7625859}, {'id': 'https://openalex.org/C18823058', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cytology', 'level': 2, 'score': 0.5596821}, {'id': 'https://openalex.org/C2777548846', 'wikidata': 'https://www.wikidata.org/wiki/Q7900629', 'display_name': 'Urine cytology', 'level': 4, 'score': 0.5212848}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.5209521}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.4659392}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.41011015}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.40994012}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.35991806}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.35685083}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.33393008}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2016.02.2496', 'pdf_url': 'https://www.auajournals.org/doi/pdf/10.1016/j.juro.2016.02.2496', 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2016.02.2496', 'pdf_url': 'https://www.auajournals.org/doi/pdf/10.1016/j.juro.2016.02.2496', 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4210609897', 'https://openalex.org/W2905256018', 'https://openalex.org/W2614687850', 'https://openalex.org/W2590476509', 'https://openalex.org/W2356218964', 'https://openalex.org/W2352314519', 'https://openalex.org/W2138050084', 'https://openalex.org/W2090121690', 'https://openalex.org/W2085161087', 'https://openalex.org/W1976830962'], 'abstract_inverted_index': {'You': [0], 'have': [1], 'accessJournal': [2], 'of': [3, 110, 121, 131, 142, 171, 181, 186, 191, 195, 206, 241, 258, 280, 324, 375, 405, 410, 416, 457, 469], 'UrologyBladder': [4], 'Cancer:': [5], 'Non-Invasive': [6], 'I1': [7], 'Apr': [8], '2016MP13-15': [9], 'MOLECULAR': [10, 19], 'URINE': [11], 'CYTOLOGY': [12], '–': [13], 'BLADDER': [14, 25], 'EPICHECK': [15], 'IS': [16], 'A': [17, 447], 'NOVEL': [18], 'DIAGNOSTIC': [20], 'TOOL': [21], 'FOR': [22], 'MONITORING': [23], 'OF': [24], 'CANCER': [26], 'PATIENTS': [27], 'Adam': [28, 48, 491], 'Wasserstrom,': [29], 'Danny': [30, 52, 498], 'Frumkin,': [31], 'Zohar': [32, 56, 505], 'Dotan,': [33], 'Elena': [34, 60, 512], 'Bukin,': [35], 'Tal': [36, 64, 519], 'Gadish,': [37], 'Shiri': [38, 68, 526], 'Hanuka,': [39], 'Revital': [40, 72, 533], 'Knirsh,': [41], 'Abd': [42, 76, 540], 'Elhalim': [43, 77, 79, 541], 'Darawsha,': [44], 'and': [45, 82, 179, 227, 277, 303, 322, 343, 349, 368, 445], 'Ilan': [46, 83, 548], 'Leibovitch': [47, 85, 549], 'WasserstromAdam': [49], 'Wasserstrom': [50, 492], ',': [51, 55, 59, 63, 67, 71, 75, 81], 'FrumkinDanny': [53], 'Frumkin': [54, 499], 'DotanZohar': [57], 'Dotan': [58, 506], 'BukinElena': [61], 'Bukin': [62, 513], 'GadishTal': [65], 'Gadish': [66, 520], 'HanukaShiri': [69], 'Hanuka': [70, 527], 'KnirshRevital': [73], 'Knirsh': [74, 534], 'DarawshaAbd': [78], 'Darawsha': [80, 542], 'LeibovitchIlan': [84], 'View': [86], 'All': [87, 556], 'Author': [88], 'Informationhttps://doi.org/10.1016/j.juro.2016.02.2496AboutPDF': [89], 'ToolsAdd': [90], 'to': [91, 175, 184], 'favoritesDownload': [92], 'CitationsTrack': [93], 'CitationsPermissionsReprints': [94], 'ShareFacebookTwitterLinked': [95], 'InEmail': [96], 'INTRODUCTION': [97], 'AND': [98], 'OBJECTIVES': [99], 'Bladder': [100, 214, 253, 312, 331, 363, 385, 399], 'EpiCheck': [101, 254, 313, 332, 364, 386, 400], 'is': [102, 164, 365], 'a': [103, 129, 140, 148, 189, 366, 464], 'novel': [104], 'DNA': [105, 122, 449], 'methylation-based': [106], 'assay': [107, 183, 371], 'for': [108, 167, 345, 372], 'detection': [109, 374], 'bladder': [111], 'cancer': [112], '(BC)': [113], 'in': [114, 128, 157, 188, 239, 270, 377, 408, 454], 'voided': [115, 378], 'urine': [116, 145, 159, 199, 379, 406], 'samples,': [117], 'based': [118], 'on': [119], 'identification': [120], 'methylation': [123, 155], 'changes': [124], 'associated': [125], 'with': [126, 193, 204, 213, 347, 356, 383, 391], 'BC': [127, 207, 263, 301, 376, 411], 'panel': [130], '15': [132], 'genomic': [133], 'biomarkers.': [134], 'The': [135, 169, 338], 'assay,': [136], 'which': [137], 'acts': [138], 'as': [139], 'sort': [141], 'user-independent': [143], '"molecular': [144], 'cytology",': [146], 'generates': [147], 'numerical': [149], 'EpiScore': [150, 162, 340], '(0-100)': [151], 'reflecting': [152], 'the': [153, 158, 177, 182, 249, 325, 373, 414, 455], 'overall': [154, 256, 278], 'level': [156], 'sample.': [160], 'An': [161], '=60': [163], 'considered': [165], 'positive': [166], 'BC.': [168, 196, 222], 'aim': [170], 'this': [172, 496, 503, 510, 517, 524, 531, 538, 546, 553], 'study': [173], 'was': [174, 246, 290, 341], 'compare': [176], 'sensitivity': [178, 257, 390], 'specificity': [180, 279], 'that': [185, 317, 327, 398], 'cytology': [187, 294, 407], 'population': [190], 'patients': [192, 203, 217, 346, 412], 'history': [194, 205], 'METHODS': [197], 'Voided': [198], 'samples': [200], 'from': [201, 463], '222': [202], 'undergoing': [208], 'routine': [209], 'surveillance': [210], 'were': [211, 237, 318, 328, 333], 'tested': [212], 'EpiCheck.': [215], '40/222': [216], '(18%)': [218], 'had': [219, 255, 295], 'biopsy-proven': [220], 'recurrent': [221], '(16-Ta,': [223], '11-T1,': [224], '3-T2,': [225], '11-CIS': [226], '2': [228, 232], 'unspecified)': [229], '(19-LG,': [230], '19-HG,': [231], 'unspecified).': [233], 'Cytology': [234], 'evaluation': [235], 'results': [236, 396], 'available': [238], '175': [240], 'these': [242], 'samples.': [243, 380], 'Statistical': [244], 'analysis': [245], 'performed': [247], 'using': [248], 'Kolmogorov-Smirnov': [250], 'test.': [251], 'RESULTS': [252], '90%,': [259], 'correctly': [260, 282, 298, 306], 'diagnosing': [261, 283, 299, 307], '36/40': [262], 'cases': [264, 302], '(sensitivity': [265], 'breakdown:': [266], '81%,100%,100%,91%,': [267], '84%,': [268], '95%;': [269], 'TA,': [271], 'T1,T2,': [272], 'CIS,': [273], 'LG,': [274], 'HG': [275, 350], 'respectively)': [276], '83%,': [281], '151/182': [284], 'cancer-free': [285, 309], 'patients.': [286, 310], 'Negative': [287], 'Predictive': [288], 'Value': [289], '97%.': [291], 'In': [292, 381], 'comparison': [293, 382], '38%': [296], 'sensitivity,': [297], '5/13': [300], '96%': [304], 'specificity,': [305], '155/162': [308], 'Significantly,': [311], 'detected': [314, 319], 'all': [315, 323], 'tumors': [316, 326], 'by': [320, 330, 336, 495, 502, 509, 516, 523, 530, 537, 545, 552], 'cytology,': [321, 384], 'missed': [329, 335], 'also': [334], 'cytology.': [337], 'average': [339], '69': [342], '85': [344], 'LG': [348], 'tumors,': [351], 'respectively,': [352], 'hence': [353], 'significantly': [354, 388], 'correlated': [355], 'tumor': [357], 'grade': [358], '(p': [359], '=': [360], '0.006).': [361], 'CONCLUSIONS': [362], 'sensitive': [367], 'specific': [369], 'operator-independent': [370], 'has': [387], 'higher': [389], 'somewhat': [392], 'lower': [393], 'specificity.': [394], 'Our': [395], 'suggest': [397], 'can': [401], 'be': [402], 'used': [403], 'instead': [404], 'monitoring': [409], 'without': [413], 'risk': [415], 'missing': [417], 'recurrences.': [418], '©': [419], '2016FiguresReferencesRelatedDetailsCited': [420], 'byTerrito': [421], 'A,': [422, 424, 438], 'Gallioli': [423], 'Diana': [425], 'P,': [426], 'Boissier': [427], 'R,': [428], 'Fontana': [429], 'M,': [430], 'Gaya': [431], 'J,': [432, 436], 'Sanguedolce': [433], 'F,': [434, 442], 'Calderón': [435], 'Piana': [437], 'Fontanet': [439], 'S,': [440], 'Algaba': [441], 'Palou': [443], 'J': [444], 'Breda': [446], '(2022)': [448], 'Methylation': [450], 'Urine': [451], 'Biomarkers': [452], 'Test': [453], 'Diagnosis': [456], 'Upper': [458], 'Tract': [459], 'Urothelial': [460], 'Carcinoma:': [461], 'Results': [462], 'Single-Center': [465], 'Prospective': [466], 'Clinical': [467], 'TrialJournal': [468], 'Urology,': [470], 'VOL.': [471], '208,': [472], 'NO.': [473], '3,': [474], '(570-579),': [475], 'Online': [476], 'publication': [477], 'date:': [478], '1-Sep-2022.': [479], 'Volume': [480], '195Issue': [481], '4SApril': [482], '2016Page:': [483], 'e140': [484], 'Advertisement': [485, 557, 558], 'Copyright': [486], '&': [487], 'Permissions©': [488], '2016MetricsAuthor': [489], 'Information': [490], 'More': [493, 500, 507, 514, 521, 528, 535, 543, 550], 'articles': [494, 501, 508, 515, 522, 529, 536, 544, 551], 'author': [497, 504, 511, 518, 525, 532, 539, 547, 554], 'Expand': [555], 'PDF': [559], 'downloadLoading': [560], '...': [561]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2314049273', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-17T09:11:53.146456', 'created_date': '2016-06-24'}