Abstract: Intercellular adhesion molecules 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCM-l) play important roles in the inflammatory process of cerebral ischemic injury. The expression of ICAM-l and VCAM-1 increases following cerebral ischemia; ICAM1 and VCAM-l promote ischemic inflammation through mediating leukocytes adhesion to the endothelial cells and eventually migration into brain tissue; the inhibition of the overexpression and effect of ICAM-l and VCAM-l can reduce cerebral ischemic injury.
Publication Year: 2005
Publication Date: 2005-11-20
Language: en
Type: article
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