Publication Information

{'id': 'https://openalex.org/W2293680867', 'doi': None, 'title': 'The protective effects of butylphthalide on amyloid β peptide25-35 induced apoptosis in PC-12 cells.', 'display_name': 'The protective effects of butylphthalide on amyloid β peptide25-35 induced apoptosis in PC-12 cells.', 'publication_year': 2010, 'publication_date': '2010-01-01', 'ids': {'openalex': 'https://openalex.org/W2293680867', 'mag': '2293680867'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGYK201006018.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764587263', 'display_name': 'Zhongguo Yike Daxue xuebao', 'issn_l': '0258-4646', 'issn': ['0258-4646'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4324004212', 'host_organization_name': 'CNKI', 'host_organization_lineage': ['https://openalex.org/P4324004212'], 'host_organization_lineage_names': ['CNKI'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027855928', 'display_name': 'Yu-huan Cui', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I91656880', 'display_name': 'China Medical University', 'ror': 'https://ror.org/032d4f246', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91656880']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Cui YuHuan', 'raw_affiliation_strings': ['Department of Thoracic Surgery,Shengjing Hospital,China Medical University,Shenyang 110004,China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery,Shengjing Hospital,China Medical University,Shenyang 110004,China', 'institution_ids': ['https://openalex.org/I91656880']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055219102', 'display_name': 'Chaodong Zhang', 'orcid': 'https://orcid.org/0000-0002-3757-4310'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zhang ChaoDong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5048661019', 'display_name': 'Yulei Wei', 'orcid': 'https://orcid.org/0000-0002-4284-8558'}, 'institutions': [{'id': 'https://openalex.org/I91656880', 'display_name': 'China Medical University', 'ror': 'https://ror.org/032d4f246', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91656880']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei YuLei', 'raw_affiliation_strings': ['Department of Thoracic Surgery,Shengjing Hospital,China Medical University,Shenyang 110004,China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery,Shengjing Hospital,China Medical University,Shenyang 110004,China', 'institution_ids': ['https://openalex.org/I91656880']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 64}, 'biblio': {'volume': '39', 'issue': '6', 'first_page': '452', 'last_page': '455'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13731', 'display_name': 'Advanced Computing and Algorithms', 'score': 0.9323, 'subfield': {'id': 'https://openalex.org/subfields/3322', 'display_name': 'Urban Studies'}, 'field': {'id': 'https://openalex.org/fields/33', 'display_name': 'Social Sciences'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/viability-assay', 'display_name': 'Viability assay', 'score': 0.77973783}, {'id': 'https://openalex.org/keywords/mtt-assay', 'display_name': 'MTT assay', 'score': 0.64024055}], 'concepts': [{'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.7933903}, {'id': 'https://openalex.org/C53227056', 'wikidata': 'https://www.wikidata.org/wiki/Q189152', 'display_name': 'Viability assay', 'level': 3, 'score': 0.77973783}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.6528691}, {'id': 'https://openalex.org/C2780783641', 'wikidata': 'https://www.wikidata.org/wiki/Q738686', 'display_name': 'MTT assay', 'level': 3, 'score': 0.64024055}, {'id': 'https://openalex.org/C28859421', 'wikidata': 'https://www.wikidata.org/wiki/Q39572', 'display_name': 'Mitochondrion', 'level': 2, 'score': 0.62773085}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5901856}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.51994526}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.48005116}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.33911487}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.32641923}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.23636785}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGYK201006018.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764587263', 'display_name': 'Zhongguo Yike Daxue xuebao', 'issn_l': '0258-4646', 'issn': ['0258-4646'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4324004212', 'host_organization_name': 'CNKI', 'host_organization_lineage': ['https://openalex.org/P4324004212'], 'host_organization_lineage_names': ['CNKI'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3041262135', 'https://openalex.org/W3032212079', 'https://openalex.org/W3031934620', 'https://openalex.org/W3029987855', 'https://openalex.org/W3026425417', 'https://openalex.org/W3013414737', 'https://openalex.org/W2991382848', 'https://openalex.org/W2608724518', 'https://openalex.org/W2385470756', 'https://openalex.org/W2381399423', 'https://openalex.org/W2372402511', 'https://openalex.org/W2368397312', 'https://openalex.org/W2358867230', 'https://openalex.org/W2353461580', 'https://openalex.org/W2348364289', 'https://openalex.org/W2297734698', 'https://openalex.org/W2119131323', 'https://openalex.org/W2004253809', 'https://openalex.org/W1974676081', 'https://openalex.org/W1974279685'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'investigate': [2], 'the': [3, 37, 55, 72, 86, 94, 97, 109, 117, 127, 130, 141, 149, 154], 'protective': [4], 'effects': [5, 56], 'of': [6, 43, 57, 103, 114, 126], 'dl-3-n-butylphthalide(NBP)on': [7], 'amyloid': [8], 'β': [9], 'peptide': [10], '25-35(Aβ25-35)-induced': [11], 'apoptosis': [12, 146], 'in': [13, 96, 108, 116, 129, 143], 'PC-12': [14], 'cells.Methods': [15], 'Cultured': [16], 'PC12': [17, 38], 'cells': [18, 95, 120], 'were': [19, 46, 63], 'divided': [20], 'into': [21], '6': [22], 'groups:normal': [23], 'group,Aβ25-35': [24], 'treated': [25], 'model': [26, 98, 131], 'group,0.1,1.0,10,100': [27], 'μmol/L': [28, 81], 'NBP': [29, 67, 82, 110, 118, 138], 'pretreatment': [30, 68], 'groups.MTT': [31], 'assay': [32], 'was': [33, 121], 'employed': [34], 'to': [35, 53], 'analyze': [36], 'cell': [39, 73, 128], 'viability.The': [40], 'ultrastructural': [41], 'changes': [42], 'neuronal': [44, 104], 'mitochondria': [45, 105, 142], 'viewed': [47], 'under': [48], 'transmission': [49], 'electron': [50], 'microscope.In': [51], 'order': [52], 'observe': [54], 'oxidative': [58], 'stress,MDA': [59], 'and': [60, 101, 152], 'SOD': [61, 115, 155], 'activities': [62], 'detected': [64], 'by': [65, 76, 90, 147], 'spectrophotometry.Results': [66], 'could': [69, 83, 139], 'significantly': [70, 84], 'prevent': [71], 'viability': [74, 87], 'induced': [75, 89, 145], 'Aβ25-35(P': [77, 91], '0.05).Pretreatment': [78], 'with': [79, 93], '10': [80], 'inhibit': [85], 'decrease': [88], '0.05).Compared': [92], 'group,the': [99], 'number': [100], 'morphology': [102], 'changed': [106], 'distinctly': [107], 'pretreated': [111, 119], 'cells.The': [112], 'activity': [113, 134, 151], 'obviously': [122], 'higher': [123], 'than': [124], 'that': [125], 'group,while': [132], 'MDA': [133, 150], 'had': [135], 'opposite': [136], 'result.Conclusion': [137], 'protect': [140], 'Aβ25-35': [144], 'inhibiting': [148], 'activating': [153], 'activity.': [156]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2293680867', 'counts_by_year': [], 'updated_date': '2024-12-11T19:54:59.771850', 'created_date': '2016-06-24'}