Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2291647830', 'doi': 'https://doi.org/10.1016/j.imbio.2015.05.011', 'title': 'A nuclear factor-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates GVHD in allogeneic bone marrow transplantation', 'display_name': 'A nuclear factor-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates GVHD in allogeneic bone marrow transplantation', 'publication_year': 2015, 'publication_date': '2015-09-01', 'ids': {'openalex': 'https://openalex.org/W2291647830', 'doi': 'https://doi.org/10.1016/j.imbio.2015.05.011', 'mag': '2291647830', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26004346'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.imbio.2015.05.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S164377831', 'display_name': 'Immunobiology', 'issn_l': '0171-2985', 'issn': ['0171-2985', '1878-3279'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5023059007', 'display_name': 'Sohsaku Yamanouchi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sohsaku Yamanouchi', 'raw_affiliation_strings': ['Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103445950', 'display_name': 'Yasushi Adachi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}, {'id': 'https://openalex.org/I4210141182', 'display_name': 'Toyooka Hospital', 'ror': 'https://ror.org/04tkt0z61', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210141182']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Yasushi Adachi', 'raw_affiliation_strings': ['Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'Division of Surgical Pathology, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}, {'raw_affiliation_string': 'Division of Surgical Pathology, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan', 'institution_ids': ['https://openalex.org/I4210141182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070575551', 'display_name': 'Tomohiko Shimo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomohiko Shimo', 'raw_affiliation_strings': ['Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068027963', 'display_name': 'Kazuo Umezawa', 'orcid': 'https://orcid.org/0000-0001-9235-4874'}, 'institutions': [{'id': 'https://openalex.org/I16528096', 'display_name': 'Aichi Medical University', 'ror': 'https://ror.org/02h6cs343', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I16528096']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuo Umezawa', 'raw_affiliation_strings': ['Department of Molecular Target Medicine Screening, Aichi Medical University School of Medicine, Nagakute, Aichi 480-1195, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Target Medicine Screening, Aichi Medical University School of Medicine, Nagakute, Aichi 480-1195, Japan', 'institution_ids': ['https://openalex.org/I16528096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070710180', 'display_name': 'Mitsuhiko Okigaki', 'orcid': None}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mitsuhiko Okigaki', 'raw_affiliation_strings': ['Department of Internal Medicine, Otokoyama Hospital, Yawata City, Kyoto 614-8366, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Otokoyama Hospital, Yawata City, Kyoto 614-8366, Japan', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038944563', 'display_name': 'Shoji Tsuji', 'orcid': 'https://orcid.org/0000-0003-3607-8355'}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shoji Tsuji', 'raw_affiliation_strings': ['Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100351339', 'display_name': 'Ming Li', 'orcid': 'https://orcid.org/0000-0001-8270-2070'}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ming Li', 'raw_affiliation_strings': ['Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102770246', 'display_name': 'Junji Takaya', 'orcid': 'https://orcid.org/0000-0001-9448-2327'}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Junji Takaya', 'raw_affiliation_strings': ['Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031282361', 'display_name': 'Tomohiro Kuge', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210141182', 'display_name': 'Toyooka Hospital', 'ror': 'https://ror.org/04tkt0z61', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210141182']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomohiro Kuge', 'raw_affiliation_strings': ['Department of Clinical Laboratory, Toyooka Hospital, Tobera, Toyooka City, Hyogo 668-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Laboratory, Toyooka Hospital, Tobera, Toyooka City, Hyogo 668-8501, Japan', 'institution_ids': ['https://openalex.org/I4210141182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062623525', 'display_name': 'Susumu Ikehara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Susumu Ikehara', 'raw_affiliation_strings': ['Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5039523570', 'display_name': 'Kazunari Kaneko', 'orcid': 'https://orcid.org/0000-0002-8215-0832'}, 'institutions': [{'id': 'https://openalex.org/I126884977', 'display_name': 'Kansai Medical University', 'ror': 'https://ror.org/001xjdh50', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I126884977']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazunari Kaneko', 'raw_affiliation_strings': ['Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan', 'institution_ids': ['https://openalex.org/I126884977']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5103445950'], 'corresponding_institution_ids': ['https://openalex.org/I126884977', 'https://openalex.org/I4210141182'], 'apc_list': {'value': 2930, 'currency': 'USD', 'value_usd': 2930, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.692, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.790259, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '220', 'issue': '9', 'first_page': '1059', 'last_page': '1066'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10345', 'display_name': 'Hematopoietic Stem Cell Biology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10345', 'display_name': 'Hematopoietic Stem Cell Biology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Natural Killer Cells in Immunity', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Innate Immune Recognition and Signaling Pathways', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hematopoietic-cell-transplantation', 'display_name': 'Hematopoietic Cell Transplantation', 'score': 0.465993}, {'id': 'https://openalex.org/keywords/ratón', 'display_name': 'Ratón', 'score': 0.44502848}], 'concepts': [{'id': 'https://openalex.org/C2780931953', 'wikidata': 'https://www.wikidata.org/wiki/Q9371', 'display_name': 'Spleen', 'level': 2, 'score': 0.75360775}, {'id': 'https://openalex.org/C2780007613', 'wikidata': 'https://www.wikidata.org/wiki/Q546523', 'display_name': 'Bone marrow', 'level': 2, 'score': 0.69458455}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.5999309}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.54699737}, {'id': 'https://openalex.org/C2994180119', 'wikidata': 'https://www.wikidata.org/wiki/Q1128050', 'display_name': 'Bone marrow transplantation', 'level': 3, 'score': 0.5021937}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4855032}, {'id': 'https://openalex.org/C2777928079', 'wikidata': 'https://www.wikidata.org/wiki/Q2677027', 'display_name': 'Ratón', 'level': 2, 'score': 0.44502848}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.37785697}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3233442}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.20054421}], 'mesh': [{'descriptor_ui': 'D001549', 'descriptor_name': 'Benzamides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D016026', 'descriptor_name': 'Bone Marrow Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003512', 'descriptor_name': 'Cyclohexanones', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D050378', 'descriptor_name': 'T-Lymphocytes, Regulatory', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000906', 'descriptor_name': 'Antibodies', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D000906', 'descriptor_name': 'Antibodies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001549', 'descriptor_name': 'Benzamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003512', 'descriptor_name': 'Cyclohexanones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000637', 'qualifier_name': 'transplantation', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015996', 'descriptor_name': 'Survival Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050378', 'descriptor_name': 'T-Lymphocytes, Regulatory', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014184', 'descriptor_name': 'Transplantation, Homologous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.imbio.2015.05.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S164377831', 'display_name': 'Immunobiology', 'issn_l': '0171-2985', 'issn': ['0171-2985', '1878-3279'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26004346', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.89, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W150455313', 'https://openalex.org/W1544331058', 'https://openalex.org/W1582225547', 'https://openalex.org/W1599864954', 'https://openalex.org/W1608695296', 'https://openalex.org/W1856257731', 'https://openalex.org/W1896733117', 'https://openalex.org/W1965571575', 'https://openalex.org/W1972291817', 'https://openalex.org/W1973568671', 'https://openalex.org/W1981784113', 'https://openalex.org/W1985955648', 'https://openalex.org/W1993415901', 'https://openalex.org/W1999719081', 'https://openalex.org/W2007667352', 'https://openalex.org/W2009468743', 'https://openalex.org/W2011011085', 'https://openalex.org/W2020368567', 'https://openalex.org/W2041303685', 'https://openalex.org/W2052605694', 'https://openalex.org/W2054124482', 'https://openalex.org/W2056602603', 'https://openalex.org/W2066579263', 'https://openalex.org/W2068808306', 'https://openalex.org/W2069119579', 'https://openalex.org/W2077450760', 'https://openalex.org/W2088091432', 'https://openalex.org/W2090344650', 'https://openalex.org/W2111888637', 'https://openalex.org/W2112593734', 'https://openalex.org/W2119624288', 'https://openalex.org/W2128351952', 'https://openalex.org/W2128939799', 'https://openalex.org/W2132289468', 'https://openalex.org/W2133102544', 'https://openalex.org/W2134582625', 'https://openalex.org/W2145708130', 'https://openalex.org/W2147370017', 'https://openalex.org/W2154132418', 'https://openalex.org/W2157325100', 'https://openalex.org/W2168740346', 'https://openalex.org/W2317237666', 'https://openalex.org/W2463090882', 'https://openalex.org/W29171066', 'https://openalex.org/W3139664080', 'https://openalex.org/W34147230', 'https://openalex.org/W4236572065', 'https://openalex.org/W4285719527', 'https://openalex.org/W4390473164'], 'related_works': ['https://openalex.org/W2993296977', 'https://openalex.org/W2354402740', 'https://openalex.org/W2186681749', 'https://openalex.org/W2183383072', 'https://openalex.org/W2083819803', 'https://openalex.org/W2051955933', 'https://openalex.org/W1571012646', 'https://openalex.org/W1564182375', 'https://openalex.org/W1550379078', 'https://openalex.org/W1542394131'], 'abstract_inverted_index': {'GVHD': [0, 129], 'is': [1], 'a': [2, 20, 35, 164], 'crucial': [3], 'mortality': [4, 32], 'factor': [5], 'in': [6, 29, 34], 'allogeneic': [7], 'bone': [8], 'marrow': [9, 40], 'transplantation': [10], '(ABMT).': [11], 'In': [12], 'this': [13, 123], 'paper,': [14], 'we': [15], 'show': [16, 83], 'that': [17, 158], 'dehydroxymethylepoxyquinomicin': [18], '(DHMEQ),': [19], 'novel': [21], 'inhibitor': [22], 'of': [23, 75, 108, 116, 143, 151, 160], 'nuclear': [24], 'factor-κB,': [25], 'suppresses': [26], 'GVHD,': [27, 84, 117], 'resulting': [28], 'an': [30], 'improved': [31], 'rate': [33], 'mouse': [36], 'ABMT': [37], 'model.': [38], 'Bone': [39], 'cells': [41, 58, 137], 'from': [42, 59, 170], 'C57BL/6': [43], 'mice': [44, 61, 80, 86, 111, 121], '(B6': [45], 'mice)': [46], 'were': [47, 62, 87, 138, 153], 'transplanted': [48, 63], 'into': [49, 64], 'lethally': [50], 'irradiated': [51, 66], 'BALB/c': [52, 67], 'mice.': [53, 68, 133], 'Two': [54], 'weeks': [55], 'later,': [56], 'spleen': [57, 76], 'B6': [60], 'the': [65, 73, 79, 85, 105, 109, 131, 141, 149], 'From': [69], 'one': [70], 'week': [71], 'after': [72, 104], 'injection': [74, 142], 'cells,': [77], 'when': [78], 'started': [81], 'to': [82], 'also': [88], 'injected': [89], 'intraperitoneally': [90], 'daily': [91], 'with': [92], 'DHMEQ': [93, 152, 161], 'or': [94], 'vehicle': [95], 'only': [96], '(DMSO)': [97], 'for': [98, 167], '4': [99, 146], 'weeks.': [100], 'By': [101], '80': [102], 'days': [103], 'ABMT,': [106], '6/14': [107], 'vehicle-injected': [110, 132], '(43%)': [112], 'had': [113], 'died': [114], 'because': [115], 'whereas': [118], 'all': [119], 'DHMEQ-injected': [120], 'survived': [122], 'observation': [124], 'period': [125], 'and': [126], 'developed': [127], 'milder': [128], 'than': [130], 'When': [134], 'regulatory': [135], 'T': [136], 'reduced': [139], 'by': [140], 'anti-folate': [144], 'receptor': [145], '(FR4)': [147], 'antibody,': [148], 'effects': [150], 'reduced.': [154], 'These': [155], 'findings': [156], 'suggest': [157], 'administration': [159], 'could': [162], 'become': [163], 'new': [165], 'strategy': [166], 'preventing': [168], 'fatalities': [169], 'GVHD.': [171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2291647830', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}], 'updated_date': '2024-09-13T11:53:03.417711', 'created_date': '2016-06-24'}