Sip-jeon-dea-bo-tang, a traditional herbal medicine, ameliorates cisplatin-induced anorexia via the activation of JAK1/STAT3-mediated leptin and IL-6 production in the fat tissue of mice

Name: Work Video:
Duration: 3 min 30 s
Sang‐Mi Woo; Youn Kyung Choi; AH-JEONG KIM; Yee Jin Yun; Yong Cheol Shin; Sung‐Gook Cho; Seong‐Gyu Ko
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[45], 'widely': [46], 'used': [47, 60], 'treat': [49], 'problems': [50], 'appetite;': [52], 'sip-jeon-dea-bo-tang': [53], '(SJDBT)': [54], 'is': [55], 'one': [56], 'those': [58], 'the': [62, 87, 106, 114, 123, 129, 136, 150, 157, 162, 168, 181], 'anorexia.': [65, 74], 'The': [66, 96], 'present': [67, 169], 'study': [68], 'demonstrated': [69], 'that': [70, 102, 172], 'SJDBT': [71, 85, 103, 121, 145, 173], 'ameliorated': [72, 174], 'cisplatin-induced': [73, 88, 175], 'a': [76], 'mouse': [77], 'model': [78], 'chemotherapy-induced': [80], 'anorexia,': [81, 176], 'oral': [82], 'administration': [83], 'prevented': [86], 'reduction': [89], 'food': [91], 'intake,': [92], 'inhibiting': [93], 'weight': [94], 'loss.': [95], 'results': [97, 170], 'multiplex': [99], 'assays': [100], 'showed': [101], 'only': [104], 'altered': [105], 'levels': [107, 137, 151], 'interleukin': [109], '(IL)-6': [110], 'leptin': [112, 125, 141, 153], 'in': [113, 156, 180], 'serum': [115, 124, 130, 140], 'fat': [117, 158], 'tissue.': [118], 'addition,': [120], 'maintained': [122], 'level': [126], 'increased': [128], 'IL-6': [131, 155], 'level,': [132], 'whereas': [133], 'cisplatin': [134], 'reduced': [135], 'both': [139], 'IL‑6.': [143], 'Furthermore,': [144], 'was': [146], 'revealed': [147, 171], 'increase': [149], 'tissue': [159], 'by': [160], 'activating': [161], 'JAK1/STAT3': [163], 'signaling': [164], 'pathway.': [165], 'conclusion,': [167], 'suggesting': [177], 'usefulness': [179], 'prevention': [182], 'chemotherapy.': [186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2282205165', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}], 'updated_date': '2024-12-24T12:59:36.341880', 'created_date': '2016-06-24'}
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