Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2279580478', 'doi': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'title': 'CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast', 'display_name': 'CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast', 'publication_year': 2016, 'publication_date': '2016-01-22', 'ids': {'openalex': 'https://openalex.org/W2279580478', 'doi': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'mag': '2279580478', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26803803', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4830896'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S175155502', 'display_name': 'Current Opinion in Structural Biology', 'issn_l': '0959-440X', 'issn': ['0959-440X', '1879-033X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5002648229', 'display_name': 'Thi Hoang Duong Nguyen', 'orcid': 'https://orcid.org/0000-0002-2180-3430'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Thi Hoang Duong Nguyen', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075304072', 'display_name': 'Wojciech P. Galej', 'orcid': 'https://orcid.org/0000-0001-8859-5229'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Wojciech P Galej', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062880972', 'display_name': 'Sebastian M. Fica', 'orcid': 'https://orcid.org/0000-0001-9186-0361'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Sebastian M Fica', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039438506', 'display_name': 'Pei-Chun Lin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Pei-Chun Lin', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101891123', 'display_name': 'Andrew J. Newman', 'orcid': 'https://orcid.org/0000-0003-4077-4302'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'Andrew J Newman', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068936914', 'display_name': 'Kiyoshi Nagai', 'orcid': 'https://orcid.org/0000-0003-1785-6510'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'Kiyoshi Nagai', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH UK', 'institution_ids': ['https://openalex.org/I170203145']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5101891123', 'https://openalex.org/A5068936914'], 'corresponding_institution_ids': ['https://openalex.org/I170203145', 'https://openalex.org/I170203145'], 'apc_list': {'value': 4530, 'currency': 'USD', 'value_usd': 4530, 'provenance': 'doaj'}, 'apc_paid': {'value': 4530, 'currency': 'USD', 'value_usd': 4530, 'provenance': 'doaj'}, 'fwci': 1.331, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 47, 'citation_normalized_percentile': {'value': 0.51643, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '36', 'issue': None, 'first_page': '48', 'last_page': '57'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/snrnp', 'display_name': 'snRNP', 'score': 0.98083496}, {'id': 'https://openalex.org/keywords/spliceosome', 'display_name': 'Spliceosome', 'score': 0.9661547}, {'id': 'https://openalex.org/keywords/small-nuclear-rna', 'display_name': 'Small nuclear RNA', 'score': 0.8601693}, {'id': 'https://openalex.org/keywords/prp24', 'display_name': 'Prp24', 'score': 0.7244821}, {'id': 'https://openalex.org/keywords/minor-spliceosome', 'display_name': 'Minor spliceosome', 'score': 0.59454644}, {'id': 'https://openalex.org/keywords/small-nuclear-ribonucleoprotein', 'display_name': 'Small nuclear ribonucleoprotein', 'score': 0.48535243}, {'id': 'https://openalex.org/keywords/group-ii-intron', 'display_name': 'Group II intron', 'score': 0.4433554}], 'concepts': [{'id': 'https://openalex.org/C68483431', 'wikidata': 'https://www.wikidata.org/wiki/Q2076770', 'display_name': 'snRNP', 'level': 5, 'score': 0.98083496}, {'id': 'https://openalex.org/C40000846', 'wikidata': 'https://www.wikidata.org/wiki/Q915868', 'display_name': 'Spliceosome', 'level': 5, 'score': 0.9661547}, {'id': 'https://openalex.org/C100299639', 'wikidata': 'https://www.wikidata.org/wiki/Q284578', 'display_name': 'Small nuclear RNA', 'level': 5, 'score': 0.8601693}, {'id': 'https://openalex.org/C54458228', 'wikidata': 'https://www.wikidata.org/wiki/Q237218', 'display_name': 'RNA splicing', 'level': 4, 'score': 0.85123825}, {'id': 'https://openalex.org/C52990999', 'wikidata': 'https://www.wikidata.org/wiki/Q7252931', 'display_name': 'Prp24', 'level': 5, 'score': 0.7244821}, {'id': 'https://openalex.org/C94671646', 'wikidata': 'https://www.wikidata.org/wiki/Q207551', 'display_name': 'Intron', 'level': 3, 'score': 0.6762126}, {'id': 'https://openalex.org/C60542250', 'wikidata': 'https://www.wikidata.org/wiki/Q21105762', 'display_name': 'Minor spliceosome', 'level': 5, 'score': 0.59454644}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.51008874}, {'id': 'https://openalex.org/C2908584439', 'wikidata': 'https://www.wikidata.org/wiki/Q2076770', 'display_name': 'Small nuclear ribonucleoprotein', 'level': 5, 'score': 0.48535243}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.480069}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.46272388}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.44400367}, {'id': 'https://openalex.org/C64962909', 'wikidata': 'https://www.wikidata.org/wiki/Q5611160', 'display_name': 'Group II intron', 'level': 5, 'score': 0.4433554}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.36808842}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1591652}, {'id': 'https://openalex.org/C41258723', 'wikidata': 'https://www.wikidata.org/wiki/Q2919111', 'display_name': 'RNA-dependent RNA polymerase', 'level': 4, 'score': 0.13249308}], 'mesh': [{'descriptor_ui': 'D020285', 'descriptor_name': 'Cryoelectron Microscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D046911', 'descriptor_name': 'Macromolecular Substances', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': True}, {'descriptor_ui': 'D046911', 'descriptor_name': 'Macromolecular Substances', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D017381', 'descriptor_name': 'Spliceosomes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': True}, {'descriptor_ui': 'D017381', 'descriptor_name': 'Spliceosomes', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046911', 'descriptor_name': 'Macromolecular Substances', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009690', 'descriptor_name': 'Nucleic Acid Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012342', 'descriptor_name': 'RNA, Small Nuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012342', 'descriptor_name': 'RNA, Small Nuclear', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012342', 'descriptor_name': 'RNA, Small Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012568', 'descriptor_name': 'Schizosaccharomyces', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012568', 'descriptor_name': 'Schizosaccharomyces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017381', 'descriptor_name': 'Spliceosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S175155502', 'display_name': 'Current Opinion in Structural Biology', 'issn_l': '0959-440X', 'issn': ['0959-440X', '1879-033X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4830896', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830896', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26803803', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.sbi.2015.12.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S175155502', 'display_name': 'Current Opinion in Structural Biology', 'issn_l': '0959-440X', 'issn': ['0959-440X', '1879-033X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320307844', 'funder_display_name': 'European Molecular Biology Organization', 'award_id': None}, {'funder': 'https://openalex.org/F4320334626', 'funder_display_name': 'Medical Research Council', 'award_id': 'MC_U105184330'}], 'datasets': [], 'versions': [], 'referenced_works_count': 72, 'referenced_works': ['https://openalex.org/W1516160268', 'https://openalex.org/W1844679536', 'https://openalex.org/W1876329184', 'https://openalex.org/W1918332224', 'https://openalex.org/W1965137486', 'https://openalex.org/W1976708319', 'https://openalex.org/W1979491817', 'https://openalex.org/W1979564291', 'https://openalex.org/W1979765627', 'https://openalex.org/W1979907792', 'https://openalex.org/W1983568945', 'https://openalex.org/W1984116290', 'https://openalex.org/W1984962092', 'https://openalex.org/W1988455121', 'https://openalex.org/W1989547144', 'https://openalex.org/W1995936356', 'https://openalex.org/W1997809603', 'https://openalex.org/W2002337973', 'https://openalex.org/W2004005433', 'https://openalex.org/W2022346667', 'https://openalex.org/W2034793790', 'https://openalex.org/W2035133245', 'https://openalex.org/W2035956243', 'https://openalex.org/W2036764180', 'https://openalex.org/W2041421251', 'https://openalex.org/W2041483465', 'https://openalex.org/W2042477053', 'https://openalex.org/W2044749033', 'https://openalex.org/W2045952340', 'https://openalex.org/W2047460000', 'https://openalex.org/W2051631967', 'https://openalex.org/W2051694176', 'https://openalex.org/W2054502896', 'https://openalex.org/W2055688390', 'https://openalex.org/W2056431625', 'https://openalex.org/W2067427645', 'https://openalex.org/W2067709324', 'https://openalex.org/W2068102111', 'https://openalex.org/W2072404529', 'https://openalex.org/W2074596531', 'https://openalex.org/W2083520043', 'https://openalex.org/W2091711066', 'https://openalex.org/W2092801170', 'https://openalex.org/W2096993874', 'https://openalex.org/W2099244854', 'https://openalex.org/W2101204654', 'https://openalex.org/W2105551327', 'https://openalex.org/W2111023901', 'https://openalex.org/W2111375641', 'https://openalex.org/W2112412611', 'https://openalex.org/W2115101918', 'https://openalex.org/W2121591967', 'https://openalex.org/W2123289678', 'https://openalex.org/W2136267657', 'https://openalex.org/W2139033823', 'https://openalex.org/W2144846867', 'https://openalex.org/W2148393113', 'https://openalex.org/W2151773461', 'https://openalex.org/W2152631455', 'https://openalex.org/W2153375374', 'https://openalex.org/W2153934067', 'https://openalex.org/W2156318993', 'https://openalex.org/W2157070284', 'https://openalex.org/W2158118253', 'https://openalex.org/W2158991904', 'https://openalex.org/W2161666622', 'https://openalex.org/W2162106282', 'https://openalex.org/W2163614438', 'https://openalex.org/W2165064583', 'https://openalex.org/W2169502075', 'https://openalex.org/W2329695769', 'https://openalex.org/W4236732918'], 'related_works': ['https://openalex.org/W4247989443', 'https://openalex.org/W2992033677', 'https://openalex.org/W2279580478', 'https://openalex.org/W2157070284', 'https://openalex.org/W2068264401', 'https://openalex.org/W2047186913', 'https://openalex.org/W2006471422', 'https://openalex.org/W2002969314', 'https://openalex.org/W1989835274', 'https://openalex.org/W1988271866'], 'abstract_inverted_index': {'The': [0, 91, 105], 'spliceosome': [1, 44, 57], 'is': [2, 52, 131], 'formed': [3], 'on': [4, 87], 'pre-mRNA': [5, 144], 'substrates': [6], 'from': [7], 'five': [8], 'small': [9], 'nuclear': [10], 'ribonucleoprotein': [11], 'particles': [12], '(U1,': [13], 'U2,': [14], 'U4/U6': [15, 30], 'and': [16, 19, 33, 37, 60, 71, 114, 116], 'U5': [17, 28, 61], 'snRNPs),': [18], 'numerous': [20], 'non-snRNP': [21], 'factors.': [22], 'Saccharomyces': [23], 'cerevisiae': [24], 'U4/U6.U5': [25, 92], 'tri-snRNP': [26, 93], 'comprises': [27], 'snRNA,': [29, 70], 'snRNA': [31], 'duplex': [32], 'approximately': [34], '30': [35], 'proteins': [36, 67], 'represents': [38], 'a': [39, 53], 'substantial': [40], 'part': [41], 'of': [42, 83, 102, 112, 119, 140, 143], 'the': [43, 99, 103, 109, 120, 141], 'before': [45], 'activation.': [46], 'Schizosaccharomyces': [47], 'pombe': [48], 'U2.U6.U5': [49, 106], 'spliceosomal': [50], 'complex': [51, 107], 'post-catalytic': [54], 'intron': [55, 74], 'lariat': [56], 'containing': [58], 'U2': [59], 'snRNPs,': [62], 'NTC': [63, 113], '(nineteen': [64], 'complex),': [65], 'NTC-related': [66], '(NTR),': [68], 'U6': [69], 'an': [72], 'RNA': [73, 125], 'lariat.': [75], 'Two': [76], 'recent': [77], 'papers': [78], 'describe': [79], 'near-complete': [80], 'atomic': [81], 'structures': [82, 135], 'these': [84], 'complexes': [85], 'based': [86], 'cryoEM': [88], 'single-particle': [89], 'analysis.': [90], 'structure': [94], 'provides': [95], 'crucial': [96], 'insight': [97], 'into': [98], 'activation': [100], 'mechanism': [101, 142], 'spliceosome.': [104], 'reveals': [108], 'striking': [110], 'architecture': [111], 'NTR': [115], 'important': [117], 'features': [118], 'group': [121], 'II': [122], 'intron-like': [123], 'catalytic': [124], 'core': [126], 'remaining': [127], 'after': [128], 'spliced': [129], 'mRNA': [130], 'released.': [132], 'These': [133], 'two': [134], 'greatly': [136], 'advance': [137], 'our': [138], 'understanding': [139], 'splicing.': [145]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2279580478', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 19}, {'year': 2016, 'cited_by_count': 11}], 'updated_date': '2024-12-10T22:25:17.526195', 'created_date': '2016-06-24'}