Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2275177904', 'doi': 'https://doi.org/10.1093/nar/gkw102', 'title': 'Mechanism of DNA loading by the DNA repair helicase XPD', 'display_name': 'Mechanism of DNA loading by the DNA repair helicase XPD', 'publication_year': 2016, 'publication_date': '2016-02-20', 'ids': {'openalex': 'https://openalex.org/W2275177904', 'doi': 'https://doi.org/10.1093/nar/gkw102', 'mag': '2275177904', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26896802', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4824113'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkw102', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/44/6/2806/18788832/gkw102.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://academic.oup.com/nar/article-pdf/44/6/2806/18788832/gkw102.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5023135666', 'display_name': 'Diana Constantinescu-Aruxandei', 'orcid': 'https://orcid.org/0000-0002-3548-8443'}, 'institutions': [{'id': 'https://openalex.org/I16835326', 'display_name': 'University of St Andrews', 'ror': 'https://ror.org/02wn5qz54', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I16835326']}, {'id': 'https://openalex.org/I4210114681', 'display_name': 'National Institute for Research & Development in Informatics', 'ror': 'https://ror.org/028rq5v79', 'country_code': 'RO', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114681']}], 'countries': ['GB', 'RO'], 'is_corresponding': False, 'raw_author_name': 'Diana Constantinescu-Aruxandei', 'raw_affiliation_strings': ['Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'institution_ids': ['https://openalex.org/I16835326']}, {'raw_affiliation_string': 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.', 'institution_ids': ['https://openalex.org/I4210114681']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062871241', 'display_name': 'Biljana Petrovic‐Stojanovska', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I16835326', 'display_name': 'University of St Andrews', 'ror': 'https://ror.org/02wn5qz54', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I16835326']}, {'id': 'https://openalex.org/I4210114681', 'display_name': 'National Institute for Research & Development in Informatics', 'ror': 'https://ror.org/028rq5v79', 'country_code': 'RO', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114681']}], 'countries': ['GB', 'RO'], 'is_corresponding': False, 'raw_author_name': 'Biljana Petrovic-Stojanovska', 'raw_affiliation_strings': ['Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'institution_ids': ['https://openalex.org/I16835326']}, {'raw_affiliation_string': 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.', 'institution_ids': ['https://openalex.org/I4210114681']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016290104', 'display_name': 'J. Carlos Penedo', 'orcid': 'https://orcid.org/0000-0002-5807-5385'}, 'institutions': [{'id': 'https://openalex.org/I16835326', 'display_name': 'University of St Andrews', 'ror': 'https://ror.org/02wn5qz54', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I16835326']}, {'id': 'https://openalex.org/I4210114681', 'display_name': 'National Institute for Research & Development in Informatics', 'ror': 'https://ror.org/028rq5v79', 'country_code': 'RO', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114681']}], 'countries': ['GB', 'RO'], 'is_corresponding': False, 'raw_author_name': 'J. Carlos Penedo', 'raw_affiliation_strings': ['Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'institution_ids': ['https://openalex.org/I16835326']}, {'raw_affiliation_string': 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.', 'institution_ids': ['https://openalex.org/I4210114681']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057021821', 'display_name': 'Malcolm F. White', 'orcid': 'https://orcid.org/0000-0003-1543-9342'}, 'institutions': [{'id': 'https://openalex.org/I16835326', 'display_name': 'University of St Andrews', 'ror': 'https://ror.org/02wn5qz54', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I16835326']}, {'id': 'https://openalex.org/I4210114681', 'display_name': 'National Institute for Research & Development in Informatics', 'ror': 'https://ror.org/028rq5v79', 'country_code': 'RO', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114681']}], 'countries': ['GB', 'RO'], 'is_corresponding': False, 'raw_author_name': 'Malcolm F. White', 'raw_affiliation_strings': ['Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'institution_ids': ['https://openalex.org/I16835326']}, {'raw_affiliation_string': 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.', 'institution_ids': ['https://openalex.org/I4210114681']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066756448', 'display_name': 'James H. Naismith', 'orcid': 'https://orcid.org/0000-0001-6744-5061'}, 'institutions': [{'id': 'https://openalex.org/I16835326', 'display_name': 'University of St Andrews', 'ror': 'https://ror.org/02wn5qz54', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I16835326']}, {'id': 'https://openalex.org/I4210114681', 'display_name': 'National Institute for Research & Development in Informatics', 'ror': 'https://ror.org/028rq5v79', 'country_code': 'RO', 'type': 'facility', 'lineage': ['https://openalex.org/I4210114681']}], 'countries': ['GB', 'RO'], 'is_corresponding': True, 'raw_author_name': 'James H. Naismith', 'raw_affiliation_strings': ['Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Sciences Research Complex, University of St Andrews, Fife KY16 9ST, UK', 'institution_ids': ['https://openalex.org/I16835326']}, {'raw_affiliation_string': 'National Institute for R&D in Chemistry and Petrochemistry, Spl. Independentei 202, 060021 Bucharest, Ro-mania.', 'institution_ids': ['https://openalex.org/I4210114681']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5066756448'], 'corresponding_institution_ids': ['https://openalex.org/I16835326', 'https://openalex.org/I4210114681'], 'apc_list': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'apc_paid': {'value': 1091, 'currency': 'EUR', 'value_usd': 1176, 'provenance': 'openapc'}, 'fwci': 2.736, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 41, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '44', 'issue': '6', 'first_page': '2806', 'last_page': '2815'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Macromolecular Crystallography Techniques', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Physiology and Genetics', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thermoplasma-acidophilum', 'display_name': 'Thermoplasma acidophilum', 'score': 0.7846278}, {'id': 'https://openalex.org/keywords/sulfolobus', 'display_name': 'Sulfolobus', 'score': 0.57977104}, {'id': 'https://openalex.org/keywords/rna-helicase-a', 'display_name': 'RNA Helicase A', 'score': 0.5357857}, {'id': 'https://openalex.org/keywords/dna-damage', 'display_name': 'DNA Damage', 'score': 0.474037}], 'concepts': [{'id': 'https://openalex.org/C161223559', 'wikidata': 'https://www.wikidata.org/wiki/Q138864', 'display_name': 'Helicase', 'level': 4, 'score': 0.9332942}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.79419863}, {'id': 'https://openalex.org/C2779198424', 'wikidata': 'https://www.wikidata.org/wiki/Q14324411', 'display_name': 'Thermoplasma acidophilum', 'level': 3, 'score': 0.7846278}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.6393038}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.6029916}, {'id': 'https://openalex.org/C2778644216', 'wikidata': 'https://www.wikidata.org/wiki/Q1209791', 'display_name': 'Sulfolobus', 'level': 4, 'score': 0.57977104}, {'id': 'https://openalex.org/C68592252', 'wikidata': 'https://www.wikidata.org/wiki/Q17913854', 'display_name': 'RNA Helicase A', 'level': 5, 'score': 0.5357857}, {'id': 'https://openalex.org/C104451858', 'wikidata': 'https://www.wikidata.org/wiki/Q2714458', 'display_name': 'Nucleotide excision repair', 'level': 4, 'score': 0.4815198}, {'id': 'https://openalex.org/C56149667', 'wikidata': 'https://www.wikidata.org/wiki/Q14908082', 'display_name': 'Transcription factor II H', 'level': 5, 'score': 0.47928756}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.42190698}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39882505}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.34654063}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.33571}, {'id': 'https://openalex.org/C550995028', 'wikidata': 'https://www.wikidata.org/wiki/Q10872', 'display_name': 'Archaea', 'level': 3, 'score': 0.19248745}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.13034767}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.122662425}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019843', 'descriptor_name': 'Archaeal Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019641', 'descriptor_name': 'DNA, Archaeal', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004277', 'descriptor_name': 'DNA, Single-Stranded', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D051759', 'descriptor_name': 'Xeroderma Pigmentosum Group D Protein', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D020816', 'descriptor_name': 'Amino Acid Motifs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019843', 'descriptor_name': 'Archaeal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019843', 'descriptor_name': 'Archaeal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019843', 'descriptor_name': 'Archaeal Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019843', 'descriptor_name': 'Archaeal Proteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018360', 'descriptor_name': 'Crystallography, X-Ray', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019641', 'descriptor_name': 'DNA, Archaeal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019641', 'descriptor_name': 'DNA, Archaeal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019641', 'descriptor_name': 'DNA, Archaeal', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004277', 'descriptor_name': 'DNA, Single-Stranded', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004277', 'descriptor_name': 'DNA, Single-Stranded', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004277', 'descriptor_name': 'DNA, Single-Stranded', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055550', 'descriptor_name': 'Protein Stability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017433', 'descriptor_name': 'Protein Structure, Secondary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016944', 'descriptor_name': 'Sulfolobus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016944', 'descriptor_name': 'Sulfolobus', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D016944', 'descriptor_name': 'Sulfolobus', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D051759', 'descriptor_name': 'Xeroderma Pigmentosum Group D Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051759', 'descriptor_name': 'Xeroderma Pigmentosum Group D Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051759', 'descriptor_name': 'Xeroderma Pigmentosum Group D Protein', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkw102', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/44/6/2806/18788832/gkw102.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4824113', 'pdf_url': 'https://europepmc.org/articles/pmc4824113?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824113', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26896802', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkw102', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/44/6/2806/18788832/gkw102.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'display_name': 'Clean water and sanitation', 'score': 0.45}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1512001995', 'https://openalex.org/W1595102998', 'https://openalex.org/W1778557300', 'https://openalex.org/W1799442365', 'https://openalex.org/W1971536893', 'https://openalex.org/W1973711348', 'https://openalex.org/W1977449047', 'https://openalex.org/W1990224501', 'https://openalex.org/W1990974875', 'https://openalex.org/W1993859324', 'https://openalex.org/W1993861248', 'https://openalex.org/W1998778934', 'https://openalex.org/W2001641653', 'https://openalex.org/W2003482071', 'https://openalex.org/W2004622851', 'https://openalex.org/W2005074055', 'https://openalex.org/W2006922696', 'https://openalex.org/W2014561472', 'https://openalex.org/W2019502407', 'https://openalex.org/W2028561215', 'https://openalex.org/W2038135691', 'https://openalex.org/W2038840577', 'https://openalex.org/W2044085946', 'https://openalex.org/W2046727880', 'https://openalex.org/W2064853448', 'https://openalex.org/W2070408712', 'https://openalex.org/W2071776351', 'https://openalex.org/W2077615862', 'https://openalex.org/W2080380418', 'https://openalex.org/W2086851455', 'https://openalex.org/W2096064309', 'https://openalex.org/W2104977828', 'https://openalex.org/W2105190461', 'https://openalex.org/W2105439835', 'https://openalex.org/W2107090468', 'https://openalex.org/W2108300953', 'https://openalex.org/W2110808180', 'https://openalex.org/W2114382972', 'https://openalex.org/W2120434953', 'https://openalex.org/W2136034321', 'https://openalex.org/W2157113406', 'https://openalex.org/W2158045853', 'https://openalex.org/W2159211495', 'https://openalex.org/W2163341755', 'https://openalex.org/W2164670061', 'https://openalex.org/W2165613558', 'https://openalex.org/W2271010587', 'https://openalex.org/W2316750555', 'https://openalex.org/W4210521569', 'https://openalex.org/W4210586598', 'https://openalex.org/W4210675630', 'https://openalex.org/W4248872320'], 'related_works': ['https://openalex.org/W2890663566', 'https://openalex.org/W2275177904', 'https://openalex.org/W2157113406', 'https://openalex.org/W2120005875', 'https://openalex.org/W2094420280', 'https://openalex.org/W2080380418', 'https://openalex.org/W2074597022', 'https://openalex.org/W2026688659', 'https://openalex.org/W1984201646', 'https://openalex.org/W1977449047'], 'abstract_inverted_index': {'The': [0, 116], 'xeroderma': [1], 'pigmentosum': [2], 'group': [3], 'D': [4], '(XPD)': [5], 'helicase': [6, 38, 98, 128, 152, 171], 'is': [7, 33, 79, 87], 'a': [8, 34, 56, 106, 147], 'component': [9], 'of': [10, 48, 59, 63, 108, 125, 135, 164, 182], 'the': [11, 27, 49, 73, 95, 136, 139, 159, 180, 183, 186], 'transcription': [12], 'factor': [13], 'IIH': [14], 'complex': [15], 'in': [16, 23, 26, 191], 'eukaryotes': [17], 'and': [18, 45, 113, 141, 188], 'plays': [19], 'an': [20, 40, 121, 175], 'essential': [21, 41], 'role': [22], 'DNA': [24, 76, 92, 157], 'repair': [25, 30], 'nucleotide': [28], 'excision': [29], 'pathway.': [31], 'XPD': [32, 52, 97, 165], "5'": [35], 'to': [36, 81, 127, 146], "3'": [37], 'with': [39, 120], 'iron-sulfur': [42], 'cluster.': [43], 'Structural': [44], 'biochemical': [46, 114], 'studies': [47], 'monomeric': [50], 'archaeal': [51, 96], 'homologues': [53], 'have': [54], 'aided': [55], 'mechanistic': [57], 'understanding': [58], 'this': [60], 'important': [61, 67], 'class': [62], 'helicase,': [64], 'but': [65], 'several': [66], 'questions': [68], 'remain': [69], 'open.': [70], 'In': [71], 'particular,': [72], 'mechanism': [74], 'for': [75], 'loading,': [77], 'which': [78], 'assumed': [80], 'require': [82], 'large': [83], 'protein': [84], 'conformational': [85], 'change,': [86], 'not': [88], 'fully': [89], 'understood.': [90], 'Here,': [91], 'binding': [93, 124, 149], 'by': [94, 132], 'from': [99, 166], 'Thermoplasma': [100], 'acidophilum': [101], 'has': [102, 174], 'been': [103], 'investigated': [104], 'using': [105], 'combination': [107], 'crystallography,': [109], 'cross-linking,': [110], 'modified': [111], 'substrates': [112], 'assays.': [115], 'data': [117], 'are': [118], 'consistent': [119], 'initial': [122], 'tight': [123], 'ssDNA': [126], 'domain': [129, 153, 172], '2,': [130], 'followed': [131], 'transient': [133], 'opening': [134], 'interface': [137, 184], 'between': [138, 185], 'Arch': [140, 187], '4FeS': [142, 189], 'domains,': [143], 'allowing': [144], 'access': [145], 'second': [148], 'site': [150], 'on': [151], '1': [154], 'that': [155, 169], 'directs': [156], 'through': [158], 'pore.': [160], 'A': [161], 'crystal': [162], 'structure': [163], 'Sulfolobus': [167], 'acidocaldiarius': [168], 'lacks': [170], '2': [173], 'otherwise': [176], 'unperturbed': [177], 'structure,': [178], 'emphasizing': [179], 'stability': [181], 'domains': [190], 'XPD.': [192]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2275177904', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 3}], 'updated_date': '2024-09-11T19:01:08.647605', 'created_date': '2016-06-24'}