Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity

Name: Work Video:
Duration: 3 min 30 s
Cinzia Giordano; Francesca Chemi; Salvatore Panza; Ines Barone; Daniela Bonofiglio; Marilena Lanzino; Angela Cordella; Antonella Campana; Adnan Hashim; Pietro Rizza; Antonella Leggio; Balázs Győrffy; Bruno M. Simões; Robert B. Clarke; Alessandro Weisz; Stefania Catalano; Sebastiano Andò
{'id': 'https://openalex.org/W2264975874', 'doi': 'https://doi.org/10.18632/oncotarget.6014', 'title': 'Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity', 'display_name': 'Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity', 'publication_year': 2015, 'publication_date': '2015-10-27', 'ids': {'openalex': 'https://openalex.org/W2264975874', 'doi': 'https://doi.org/10.18632/oncotarget.6014', 'mag': '2264975874', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26556856', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4811458'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.6014', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=6014&path%5B%5D=17913', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=6014&path%5B%5D=17913', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048878801', 'display_name': 'Cinzia Giordano', 'orcid': 'https://orcid.org/0000-0003-4969-0607'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Cinzia Giordano', 'raw_affiliation_strings': ['Centro Sanitario, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Sanitario, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065766903', 'display_name': 'Francesca Chemi', 'orcid': 'https://orcid.org/0000-0002-6652-5243'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Francesca Chemi', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020724674', 'display_name': 'Salvatore Panza', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Salvatore Panza', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046031758', 'display_name': 'Ines Barone', 'orcid': 'https://orcid.org/0000-0002-9769-1615'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Ines Barone', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054597220', 'display_name': 'Daniela Bonofiglio', 'orcid': 'https://orcid.org/0000-0002-4142-0496'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Daniela Bonofiglio', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086857323', 'display_name': 'Marilena Lanzino', 'orcid': 'https://orcid.org/0000-0002-6362-5396'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Marilena Lanzino', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066869605', 'display_name': 'Angela Cordella', 'orcid': 'https://orcid.org/0000-0001-9784-7010'}, 'institutions': [{'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210104791', 'display_name': 'SDN Istituto di Ricerca Diagnostica e Nucleare', 'ror': 'https://ror.org/01e8d4510', 'country_code': 'IT', 'type': 'other', 'lineage': ['https://openalex.org/I4210104791']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Angela Cordella', 'raw_affiliation_strings': ['IRCCS SDN (Istituto di Ricerca Diagnostica e Nucleare), Napoli, Italy'], 'affiliations': [{'raw_affiliation_string': 'IRCCS SDN (Istituto di Ricerca Diagnostica e Nucleare), Napoli, Italy', 'institution_ids': ['https://openalex.org/I4210153126', 'https://openalex.org/I4210104791']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036779332', 'display_name': 'Antonella Campana', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Antonella Campana', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102841525', 'display_name': 'Adnan Hashim', 'orcid': 'https://orcid.org/0000-0003-4736-8315'}, 'institutions': [{'id': 'https://openalex.org/I131729948', 'display_name': 'University of Salerno', 'ror': 'https://ror.org/0192m2k53', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I131729948']}, {'id': 'https://openalex.org/I184942183', 'display_name': 'University of Oslo', 'ror': 'https://ror.org/01xtthb56', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I184942183']}], 'countries': ['IT', 'NO'], 'is_corresponding': False, 'raw_author_name': 'Adnan Hashim', 'raw_affiliation_strings': ['Laboratory of Molecular Medicine and Genomics, Department of Medicine and Surgery, University of Salerno, Baronissi, Italy; Norwegian Centre for Molecular Medicine (NCMM), University of Oslo, Oslo, Norway', 'Norwegian Centre for Molecular Medicine (NCMM), University of Oslo, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Molecular Medicine and Genomics, Department of Medicine and Surgery, University of Salerno, Baronissi, Italy; Norwegian Centre for Molecular Medicine (NCMM), University of Oslo, Oslo, Norway', 'institution_ids': ['https://openalex.org/I131729948', 'https://openalex.org/I184942183']}, {'raw_affiliation_string': 'Norwegian Centre for Molecular Medicine (NCMM), University of Oslo, Oslo, Norway', 'institution_ids': ['https://openalex.org/I184942183']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022037891', 'display_name': 'Pietro Rizza', 'orcid': 'https://orcid.org/0000-0002-1267-3910'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Pietro Rizza', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081900717', 'display_name': 'Antonella Leggio', 'orcid': 'https://orcid.org/0000-0002-4373-6232'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Antonella Leggio', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023340072', 'display_name': 'Balázs Győrffy', 'orcid': 'https://orcid.org/0000-0002-5772-3766'}, 'institutions': [{'id': 'https://openalex.org/I80251312', 'display_name': 'HUN-REN Research Centre for Natural Sciences', 'ror': 'https://ror.org/03zwxja46', 'country_code': 'HU', 'type': 'facility', 'lineage': ['https://openalex.org/I4387152226', 'https://openalex.org/I80251312']}, {'id': 'https://openalex.org/I101202996', 'display_name': 'Semmelweis University', 'ror': 'https://ror.org/01g9ty582', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I101202996']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Balázs Győrffy', 'raw_affiliation_strings': ['2nd Dept. of Pediatrics, Semmelweis University, Budapest, Hungary', 'MTA TTK Lendület Cancer Biomarker Research Group, Budapest, Hungary', 'MTA-SE Pediatrics and Nephrology Research Group, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'MTA TTK Lendület Cancer Biomarker Research Group, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I80251312']}, {'raw_affiliation_string': 'MTA-SE Pediatrics and Nephrology Research Group, Budapest, Hungary', 'institution_ids': []}, {'raw_affiliation_string': '2nd Dept. of Pediatrics, Semmelweis University, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085631179', 'display_name': 'Bruno M. Simões', 'orcid': 'https://orcid.org/0000-0003-1253-6657'}, 'institutions': [{'id': 'https://openalex.org/I2799938689', 'display_name': 'Breast Cancer Now', 'ror': 'https://ror.org/02qa92s63', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2799938689']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Bruno M. Simões', 'raw_affiliation_strings': ['Breast Cancer Now Research Unit, Institute of Cancer Sciences, University Manchester, Manchester, UK'], 'affiliations': [{'raw_affiliation_string': 'Breast Cancer Now Research Unit, Institute of Cancer Sciences, University Manchester, Manchester, UK', 'institution_ids': ['https://openalex.org/I2799938689']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073495103', 'display_name': 'Robert B. Clarke', 'orcid': 'https://orcid.org/0000-0001-5407-3123'}, 'institutions': [{'id': 'https://openalex.org/I2799938689', 'display_name': 'Breast Cancer Now', 'ror': 'https://ror.org/02qa92s63', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2799938689']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Robert B. Clarke', 'raw_affiliation_strings': ['Breast Cancer Now Research Unit, Institute of Cancer Sciences, University Manchester, Manchester, UK'], 'affiliations': [{'raw_affiliation_string': 'Breast Cancer Now Research Unit, Institute of Cancer Sciences, University Manchester, Manchester, UK', 'institution_ids': ['https://openalex.org/I2799938689']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061245348', 'display_name': 'Alessandro Weisz', 'orcid': 'https://orcid.org/0000-0003-0455-2083'}, 'institutions': [{'id': 'https://openalex.org/I131729948', 'display_name': 'University of Salerno', 'ror': 'https://ror.org/0192m2k53', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I131729948']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Alessandro Weisz', 'raw_affiliation_strings': ['Laboratory of Molecular Medicine and Genomics, Department of Medicine and Surgery, University of Salerno, Baronissi, Italy'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Molecular Medicine and Genomics, Department of Medicine and Surgery, University of Salerno, Baronissi, Italy', 'institution_ids': ['https://openalex.org/I131729948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013221500', 'display_name': 'Stefania Catalano', 'orcid': 'https://orcid.org/0000-0002-6352-9628'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Stefania Catalano', 'raw_affiliation_strings': ['Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5102010816', 'display_name': 'Sebastiano Andò', 'orcid': 'https://orcid.org/0000-0002-5412-7045'}, 'institutions': [{'id': 'https://openalex.org/I45204951', 'display_name': 'University of Calabria', 'ror': 'https://ror.org/02rc97e94', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45204951']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Sebastiano Andò', 'raw_affiliation_strings': ['Centro Sanitario, University of Calabria, Arcavacata di Rende, Italy', 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy'], 'affiliations': [{'raw_affiliation_string': 'Centro Sanitario, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}, {'raw_affiliation_string': 'Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, Italy', 'institution_ids': ['https://openalex.org/I45204951']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.565, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 72, 'citation_normalized_percentile': {'value': 0.826922, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '7', 'issue': '2', 'first_page': '1262', 'last_page': '1275'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Cells and Metastasis', 'score': 0.9857, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Cells and Metastasis', 'score': 0.9857, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10489', 'display_name': 'Regulation of Appetite and Obesity', 'score': 0.9685, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12745', 'display_name': 'Dietary Effects on Health', 'score': 0.9655, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mediator', 'display_name': 'Mediator', 'score': 0.69499993}], 'concepts': [{'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.72604734}, {'id': 'https://openalex.org/C2780613262', 'wikidata': 'https://www.wikidata.org/wiki/Q223739', 'display_name': 'Leptin', 'level': 3, 'score': 0.6975441}, {'id': 'https://openalex.org/C2107291', 'wikidata': 'https://www.wikidata.org/wiki/Q14886885', 'display_name': 'Mediator', 'level': 2, 'score': 0.69499993}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6423573}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.6330734}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.5654208}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5576296}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4822317}, {'id': 'https://openalex.org/C55427017', 'wikidata': 'https://www.wikidata.org/wiki/Q1638475', 'display_name': 'Cancer stem cell', 'level': 3, 'score': 0.46512648}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.45281687}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.41550857}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.3828546}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.275504}, {'id': 'https://openalex.org/C511355011', 'wikidata': 'https://www.wikidata.org/wiki/Q12174', 'display_name': 'Obesity', 'level': 2, 'score': 0.2671079}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.13462493}], 'mesh': [{'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020738', 'descriptor_name': 'Leptin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014411', 'descriptor_name': 'Neoplastic Stem Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017154', 'descriptor_name': 'Stromal Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017077', 'descriptor_name': 'Culture Media, Conditioned', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017077', 'descriptor_name': 'Culture Media, Conditioned', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D018841', 'descriptor_name': 'HSP90 Heat-Shock Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018841', 'descriptor_name': 'HSP90 Heat-Shock Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018841', 'descriptor_name': 'HSP90 Heat-Shock Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020738', 'descriptor_name': 'Leptin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020738', 'descriptor_name': 'Leptin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020738', 'descriptor_name': 'Leptin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D061986', 'descriptor_name': 'MCF-7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014411', 'descriptor_name': 'Neoplastic Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054411', 'descriptor_name': 'Receptors, Leptin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D054411', 'descriptor_name': 'Receptors, Leptin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054411', 'descriptor_name': 'Receptors, Leptin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018874', 'descriptor_name': 'Spheroids, Cellular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D018874', 'descriptor_name': 'Spheroids, Cellular', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018874', 'descriptor_name': 'Spheroids, Cellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017154', 'descriptor_name': 'Stromal Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.6014', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=6014&path%5B%5D=17913', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4811458', 'pdf_url': 'https://europepmc.org/articles/pmc4811458?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811458', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://real.mtak.hu/34206/1/2016_Oncotarget_Ando.pdf', 'pdf_url': 'http://real.mtak.hu/34206/1/2016_Oncotarget_Ando.pdf', 'source': {'id': 'https://openalex.org/S4306400081', 'display_name': "Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4210140733', 'host_organization_name': 'Library and Information Centre of the Hungarian Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/I4210140733'], 'host_organization_lineage_names': ['Library and Information Centre of the Hungarian Academy of Sciences'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://repo.lib.semmelweis.hu//handle/123456789/5684', 'pdf_url': 'http://repo.lib.semmelweis.hu//bitstream/123456789/5684/1/oncotarget_07_1262_u.pdf', 'source': {'id': 'https://openalex.org/S4306402199', 'display_name': 'Semmelweis University Repository (Semmelweis University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I101202996', 'host_organization_name': 'Semmelweis University', 'host_organization_lineage': ['https://openalex.org/I101202996'], 'host_organization_lineage_names': ['Semmelweis University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26556856', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.6014', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=6014&path%5B%5D=17913', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.84, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 56, 'referenced_works': ['https://openalex.org/W1573024086', 'https://openalex.org/W1909192843', 'https://openalex.org/W1971550840', 'https://openalex.org/W1979538859', 'https://openalex.org/W1984413324', 'https://openalex.org/W1992514491', 'https://openalex.org/W1998353682', 'https://openalex.org/W1998543559', 'https://openalex.org/W1999356404', 'https://openalex.org/W2007518082', 'https://openalex.org/W2011540227', 'https://openalex.org/W2014287951', 'https://openalex.org/W2021822080', 'https://openalex.org/W2022441197', 'https://openalex.org/W2023828818', 'https://openalex.org/W2028298372', 'https://openalex.org/W2029979230', 'https://openalex.org/W2032369680', 'https://openalex.org/W2034712485', 'https://openalex.org/W2040935952', 'https://openalex.org/W2050939102', 'https://openalex.org/W2055970529', 'https://openalex.org/W2060185596', 'https://openalex.org/W2060892368', 'https://openalex.org/W2060925449', 'https://openalex.org/W2065650174', 'https://openalex.org/W2069409907', 'https://openalex.org/W2072914828', 'https://openalex.org/W2073483289', 'https://openalex.org/W2073759231', 'https://openalex.org/W2077740357', 'https://openalex.org/W2078145223', 'https://openalex.org/W2078719918', 'https://openalex.org/W2081928176', 'https://openalex.org/W2085134335', 'https://openalex.org/W2085934079', 'https://openalex.org/W2101885447', 'https://openalex.org/W2102552580', 'https://openalex.org/W2110430672', 'https://openalex.org/W2117701806', 'https://openalex.org/W2127617517', 'https://openalex.org/W2127913670', 'https://openalex.org/W2136178883', 'https://openalex.org/W2137657375', 'https://openalex.org/W2140628770', 'https://openalex.org/W2140987848', 'https://openalex.org/W2143383125', 'https://openalex.org/W2143768482', 'https://openalex.org/W2156734818', 'https://openalex.org/W2158255028', 'https://openalex.org/W2158734599', 'https://openalex.org/W2159640574', 'https://openalex.org/W2163113687', 'https://openalex.org/W2163210258', 'https://openalex.org/W2163292580', 'https://openalex.org/W2168972202'], 'related_works': ['https://openalex.org/W4245613501', 'https://openalex.org/W3144829101', 'https://openalex.org/W2989784815', 'https://openalex.org/W2402028051', 'https://openalex.org/W2319742058', 'https://openalex.org/W2212975813', 'https://openalex.org/W2181439996', 'https://openalex.org/W2155584699', 'https://openalex.org/W2143022745', 'https://openalex.org/W2075494673'], 'abstract_inverted_index': {'//': [0], 'Cinzia': [1], 'Giordano': [2], '1,': [3, 76], '*': [4, 9, 14, 186], ',': [5, 10, 15, 19, 23, 27, 31, 35, 40, 44, 48, 54, 59, 64, 68, 73, 402], 'Francesca': [6], 'Chemi': [7], '2,': [8, 13, 71, 77], 'Salvatore': [11], 'Panza': [12], 'Ines': [16], 'Barone': [17], '2': [18, 22, 26, 34, 43, 47, 89], 'Daniela': [20], 'Bonofiglio': [21], 'Marilena': [24], 'Lanzino': [25], 'Angela': [28], 'Cordella': [29], '3': [30, 104], 'Antonella': [32, 45], 'Campana': [33], 'Adnan': [36], 'Hashim': [37], '4,': [38], '5': [39, 132], 'Pietro': [41], 'Rizza': [42], 'Leggio': [46], 'Bal&aacute;zs': [49], 'Győrffy': [50], '7,': [51], '8,': [52], '9': [53, 177], 'Bruno': [55], 'M.': [56], 'Sim&otilde;es': [57], '6': [58, 63, 144], 'Robert': [60], 'B.': [61], 'Clarke': [62], 'Alessandro': [65], 'Weisz': [66], '4': [67, 115], 'Stefania': [69, 205], 'Catalano': [70], '**': [72, 78, 195], 'Sebastiano': [74, 201], 'And&ograve;': [75], '1': [79], 'Centro': [80], 'Sanitario,': [81], 'University': [82, 97, 127, 139, 154], 'of': [83, 91, 98, 117, 123, 128, 140, 151, 171, 256, 289, 313, 340, 371, 396, 405], 'Calabria,': [84, 99], 'Arcavacata': [85, 100], 'di': [86, 101, 108], 'Rende,': [87, 102], 'Italy': [88, 103, 114, 131], 'Department': [90, 122], 'Pharmacy,': [92], 'Health': [93], 'and': [94, 120, 125, 180, 244, 252, 272, 303, 308, 327, 338, 358, 383, 394, 437, 483], 'Nutritional': [95], 'Sciences,': [96, 153], 'IRCCS': [105], 'SDN': [106], '(Istituto': [107], 'Ricerca': [109], 'Diagnostica': [110], 'e': [111], 'Nucleare),': [112], 'Napoli,': [113], 'Laboratory': [116], 'Molecular': [118, 136], 'Medicine': [119, 124, 137], 'Genomics,': [121], 'Surgery,': [126], 'Salerno,': [129], 'Baronissi,': [130], 'Norwegian': [133], 'Centre': [134], 'for': [135], '(NCMM),': [138], 'Oslo,': [141, 142], 'Norway': [143], 'Breast': [145, 232], 'Cancer': [146, 152, 162], 'Now': [147], 'Research': [148, 164, 182], 'Unit,': [149], 'Institute': [150], 'Manchester,': [155, 156], 'UK': [157], '7': [158], 'MTA': [159], 'TTK': [160], 'Lend&uuml;let': [161], 'Biomarker': [163], 'Group,': [165, 183], 'Budapest,': [166, 175, 184], 'Hungary': [167, 176, 185], '8': [168], '2nd': [169], 'Dept.': [170], 'Pediatrics,': [172], 'Semmelweis': [173], 'University,': [174], 'MTA-SE': [178], 'Pediatrics': [179], 'Nephrology': [181], 'These': [187], 'authors': [188, 198], 'have': [189, 274], 'equally': [190], 'contributed': [191], 'to': [192, 265, 277], 'this': [193, 346], 'work': [194], 'Joint': [196], 'senior': [197], 'Correspondence': [199], 'to:': [200], 'And&ograve;,': [202], 'e-mail:': [203, 207], '[email protected]': [204], 'Catalano,': [206], '[email protected]': [208], 'Keywords:': [209], 'breast': [210, 215, 304, 328, 335, 392, 447, 479], 'cancer,': [211], 'leptin,': [212, 285], 'microenvironment,': [213], 'CAFs,': [214], 'cancer': [216, 233, 305, 336, 448, 480], 'stem': [217, 234, 375], 'cells': [218, 235, 337], 'Received:': [219], 'July': [220], '08,': [221], '2015&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;': [222, 226], 'Accepted:': [223], 'October': [224, 228], '06,': [225], 'Published:': [227], '27,': [229], '2015': [230], 'ABSTRACT': [231], '(BCSCs)': [236], 'play': [237], 'crucial': [238], 'roles': [239], 'in': [240, 317, 334, 374, 390, 414, 446, 478], 'tumor': [241, 257], 'initiation,': [242], 'metastasis': [243], 'therapeutic': [245, 262, 497], 'resistance.': [246], 'A': [247], 'strict': [248], 'dependency': [249], 'between': [250, 269], 'BCSCs': [251, 273], 'stromal': [253], 'cell': [254, 306, 376, 481], 'components': [255], 'microenvironment': [258, 271], 'exists.': [259], 'Thus,': [260], 'novel': [261], 'strategies': [263], 'aimed': [264], 'target': [266, 404, 498], 'the': [267, 275, 310, 502], 'crosstalk': [268], 'activated': [270], 'potential': [276, 311, 496], 'improve': [278], 'clinical': [279], 'outcome.': [280], 'Here,': [281], 'we': [282], 'investigated': [283], 'how': [284], 'as': [286, 398, 400], 'a': [287, 367, 403, 469, 495], 'mediator': [288], 'tumor-stromal': [290], 'interactions,': [291], 'may': [292, 493], 'affect': [293], 'BCSC': [294], 'activity': [295], 'using': [296, 468], 'patient-derived': [297, 484], 'samples': [298, 416], '(': [299, 354, 417], 'n': [300], '=': [301, 419, 422, 425, 428, 451, 454, 457, 460], '16)': [302], 'lines,': [307], 'determined': [309], 'benefit': [312], 'targeting': [314], 'leptin': [315, 341, 352, 359, 386, 406, 465, 471], 'signaling': [316, 466, 492], 'these': [318], 'model': [319], 'systems.': [320], 'Conditioned': [321], 'media': [322], '(CM)': [323], 'from': [324, 342], 'cancer-associated': [325], 'fibroblasts': [326], 'adipocytes': [329], 'significantly': [330, 474], 'increased': [331, 351, 387], 'mammosphere': [332, 362, 388, 412, 476], 'formation': [333, 389, 413, 477], 'depletion': [339], 'CM': [343, 382], 'completely': [344], 'abrogated': [345], 'effect.': [347], 'Mammosphere': [348], 'cultures': [349], 'exhibited': [350], 'receptor': [353, 472, 491], 'OBR': [355, 397, 436], ')': [356], 'expression': [357, 369, 395, 439], 'exposure': [360], 'enhanced': [361], 'formation.': [363], 'Microarray': [364], 'analyses': [365], 'revealed': [366], 'similar': [368], 'profile': [370], 'genes': [372], 'involved': [373], 'biology': [377], 'among': [378], 'mammospheres': [379], 'treated': [380], 'with': [381, 411, 442], 'leptin.': [384], 'Interestingly,': [385], 'metastatic': [391, 415], 'cancers': [393], 'well': [399], 'HSP90': [401, 438], 'signaling,': [407], 'were': [408, 440], 'directly': [409], 'correlated': [410], 'r': [418, 424], '0.68/': [420], 'p': [421, 427, 453, 459], '0.05;': [423], '0.71/': [426], '0.036,': [429], 'respectively).': [430, 462], 'Kaplan&ndash;Meier': [431], 'survival': [432, 445], 'curves': [433], 'indicated': [434], 'that': [435, 489, 499], 'associated': [441], 'reduced': [443, 475], 'overall': [444], 'patients': [449], '(HR': [450], '1.9/': [452], '0.022;': [455], 'HR': [456], '2.2/': [458], '0.00017,': [461], 'Furthermore,': [463], 'blocking': [464], 'by': [467], 'full': [470], 'antagonist': [473], 'lines': [482], 'samples.': [485], 'Our': [486], 'results': [487], 'suggest': [488], 'leptin/leptin': [490], 'represent': [494], 'can': [500], 'block': [501], 'stromal-tumor': [503], 'interactions': [504], 'driving': [505], 'BCSC-mediated': [506], 'disease': [507], 'progression.': [508]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2264975874', 'counts_by_year': [{'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 13}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 8}], 'updated_date': '2024-12-13T21:26:50.226195', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
