Publication Information

{'id': 'https://openalex.org/W2257796989', 'doi': 'https://doi.org/10.18632/oncotarget.5070', 'title': 'Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival', 'display_name': 'Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival', 'publication_year': 2015, 'publication_date': '2015-08-24', 'ids': {'openalex': 'https://openalex.org/W2257796989', 'doi': 'https://doi.org/10.18632/oncotarget.5070', 'mag': '2257796989', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26360781', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4741596'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5070', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5070&path%5B%5D=13812', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5070&path%5B%5D=13812', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111991231', 'display_name': 'Li-Ru He', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li-Ru He', 'raw_affiliation_strings': ['Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}, {'raw_affiliation_string': 'Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101048389', 'display_name': 'Ning-Fang Ma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ning-Fang Ma', 'raw_affiliation_strings': ['Department of Histology and Embryology, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Histology and Embryology, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113662648', 'display_name': 'Jie-Wei Chen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jie-Wei Chen', 'raw_affiliation_strings': ['Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}, {'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046183867', 'display_name': 'Binkui Li', 'orcid': 'https://orcid.org/0000-0003-3201-2914'}, 'institutions': [{'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bin-Kui Li', 'raw_affiliation_strings': ['The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045797751', 'display_name': 'Xin‐Yuan Guan', 'orcid': 'https://orcid.org/0000-0002-4485-6017'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}], 'countries': ['CN', 'HK'], 'is_corresponding': False, 'raw_author_name': 'Xin-Yuan Guan', 'raw_affiliation_strings': ['Departments of Clinical Oncology, The University of Hong Kong, Hong Kong, China', 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Departments of Clinical Oncology, The University of Hong Kong, Hong Kong, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111406148', 'display_name': 'Meng‐Zhong Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Meng-Zhong Liu', 'raw_affiliation_strings': ['Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}, {'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5075846774', 'display_name': 'Dan Xie', 'orcid': 'https://orcid.org/0000-0003-2242-3138'}, 'institutions': [{'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Dan Xie', 'raw_affiliation_strings': ['Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}, {'raw_affiliation_string': 'The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China', 'institution_ids': ['https://openalex.org/I157773358', 'https://openalex.org/I4210146711']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5075846774'], 'corresponding_institution_ids': ['https://openalex.org/I4210146711', 'https://openalex.org/I157773358'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.891, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.826922, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '6', 'issue': '31', 'first_page': '31181', 'last_page': '31190'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12334', 'display_name': 'Lung Cancer Research Studies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12334', 'display_name': 'Lung Cancer Research Studies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12505', 'display_name': 'Peptidase Inhibition and Analysis', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10631', 'display_name': 'Cancer, Hypoxia, and Metabolism', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.62090653}, {'id': 'https://openalex.org/C555283112', 'wikidata': 'https://www.wikidata.org/wiki/Q1637543', 'display_name': 'Carcinogenesis', 'level': 3, 'score': 0.55303925}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5316214}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.513399}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.5114173}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.49838686}, {'id': 'https://openalex.org/C2781018059', 'wikidata': 'https://www.wikidata.org/wiki/Q207609', 'display_name': 'Oncogene', 'level': 4, 'score': 0.4610362}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.44496232}, {'id': 'https://openalex.org/C2781182431', 'wikidata': 'https://www.wikidata.org/wiki/Q356033', 'display_name': 'Adenocarcinoma', 'level': 3, 'score': 0.43259516}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36260062}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3498292}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.1822674}], 'mesh': [{'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D000077192', 'descriptor_name': 'Adenocarcinoma of Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016009', 'descriptor_name': 'Chi-Square Distribution', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004265', 'descriptor_name': 'DNA Helicases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018450', 'descriptor_name': 'Disease Progression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018572', 'descriptor_name': 'Disease-Free Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005784', 'descriptor_name': 'Gene Amplification', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015971', 'descriptor_name': 'Gene Expression Regulation, Enzymologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017404', 'descriptor_name': 'In Situ Hybridization, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015999', 'descriptor_name': 'Multivariate Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016016', 'descriptor_name': 'Proportional Hazards Models', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5070', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5070&path%5B%5D=13812', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4741596', 'pdf_url': 'https://europepmc.org/articles/pmc4741596?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741596', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10722/222476', 'pdf_url': 'http://hub.hku.hk/bitstream/10722/222476/1/Content.pdf', 'source': {'id': 'https://openalex.org/S4377196271', 'display_name': 'The HKU Scholars Hub (University of Hong Kong)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I889458895', 'host_organization_name': 'University of Hong Kong', 'host_organization_lineage': ['https://openalex.org/I889458895'], 'host_organization_lineage_names': ['University of Hong Kong'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26360781', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5070', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5070&path%5B%5D=13812', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.56, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1827761694', 'https://openalex.org/W1964540535', 'https://openalex.org/W1992146030', 'https://openalex.org/W2021329627', 'https://openalex.org/W2029592915', 'https://openalex.org/W2041323674', 'https://openalex.org/W2055164218', 'https://openalex.org/W2058258230', 'https://openalex.org/W2061506015', 'https://openalex.org/W2066885008', 'https://openalex.org/W2072515444', 'https://openalex.org/W2081797598', 'https://openalex.org/W2085468423', 'https://openalex.org/W2087281552', 'https://openalex.org/W2087304710', 'https://openalex.org/W2087810003', 'https://openalex.org/W2091872354', 'https://openalex.org/W2092901172', 'https://openalex.org/W2104543228', 'https://openalex.org/W2106326014', 'https://openalex.org/W2113253176', 'https://openalex.org/W2117994949', 'https://openalex.org/W2165256123', 'https://openalex.org/W2170552969'], 'related_works': ['https://openalex.org/W3144756874', 'https://openalex.org/W2788712402', 'https://openalex.org/W2509865755', 'https://openalex.org/W2418977330', 'https://openalex.org/W2304396134', 'https://openalex.org/W2266238929', 'https://openalex.org/W2074401646', 'https://openalex.org/W2050014257', 'https://openalex.org/W2030854362', 'https://openalex.org/W1967821671'], 'abstract_inverted_index': {'//': [0], 'Li-Ru': [1], 'He': [2], '1,': [3, 12, 21, 26, 31], '2': [4, 27, 56], ',': [5, 9, 14, 18, 23, 28], 'Ning-Fang': [6], 'Ma': [7], '4': [8, 79], 'Jie-Wei': [10], 'Chen': [11], '3': [13, 32, 68], 'Bin-Kui': [15], 'Li': [16], '1': [17, 33], 'Xin-Yuan': [19], 'Guan': [20], '5': [22, 96], 'Meng-Zhong': [24], 'Liu': [25], 'Dan': [29, 111], 'Xie': [30], 'The': [34, 101, 195, 225], 'State': [35, 85], 'Key': [36, 86], 'Laboratory': [37, 87], 'of': [38, 58, 70, 81, 88, 98, 103, 159, 178, 207, 214, 222, 227, 307, 338, 346], 'Oncology': [39], 'in': [40, 152, 161, 186, 190, 218, 246, 254, 287, 291, 314], 'South': [41], 'China,': [42], 'Sun': [43, 61, 72], 'Yat-Sen': [44, 62, 73], 'University': [45, 63, 74, 102], 'Cancer': [46, 52, 64, 75], 'Center,': [47, 65, 76], 'Collaborative': [48], 'Innovation': [49], 'Center': [50], 'for': [51, 325, 361], 'Medicine,': [53], 'Guangzhou,': [54, 66, 77, 94], 'China': [55, 67, 78, 95, 108], 'Department': [57, 69, 80], 'Radiation': [59], 'Oncology,': [60, 100], 'Pathology,': [71], 'Histology': [82], 'and': [83, 175, 184, 200, 203, 212, 220, 237, 279, 297, 313, 328, 349, 357], 'Embryology,': [84], 'Respiratory': [89], 'Disease,': [90], 'Guangzhou': [91], 'Medical': [92], 'University,': [93], 'Departments': [97], 'Clinical': [99], 'Hong': [104, 106], 'Kong,': [105, 107], 'Correspondence': [109], 'to:': [110], 'Xie,': [112], 'e-mail:': [113], '[email protected]': [114], 'Keywords:': [115], 'non-small-cell': [116, 162], 'lung': [117, 163, 347, 362], 'carcinoma,': [118], 'CHD1L': [119, 138, 160, 179, 198, 208, 215, 228, 259, 308, 317, 339], 'protein,': [120], 'metastasis,': [121], 'prognosis,': [122], 'gene': [123], 'amplification': [124, 176, 213, 238], 'Received:': [125], 'May': [126], '24,': [127, 135], '2015': [128, 132, 136], 'Accepted:': [129], 'August': [130, 134], '14,': [131], 'Published:': [133], 'ABSTRACT': [137], '(chromodomain': [139], 'helicase/ATPase': [140], 'DNA': [141], 'binding': [142], 'protein': [143], '1-like': [144], 'gene)': [145], 'has': [146], 'been': [147, 168], 'demonstrated': [148, 303], 'as': [149, 321, 352], 'an': [150], 'oncogene': [151], 'hepatocellular': [153], 'carcinoma': [154, 257], '(HCC),': [155], 'however,': [156], 'the': [157, 173, 204, 294], 'role': [158], 'cancer': [164], '(NSCLC)': [165], 'tumorigenesis': [166], "hasn't": [167], 'elucidated.': [169], 'In': [170], 'this': [171], 'study,': [172], 'expression': [174, 199], 'status': [177, 267], 'were': [180, 209], 'examined': [181], 'by': [182], 'immunohistochemistry': [183], 'fluorescence': [185], 'situ': [187], 'hybridization': [188], 'respectively': [189], '248': [191], 'surgically': [192], 'resected': [193], 'NSCLCs.': [194], 'associations': [196], 'between': [197], 'clinicopathologic': [201], 'features': [202], 'prognostic': [205, 355], 'value': [206], 'analyzed.': [210], 'Overexpression': [211], 'was': [216, 249, 261, 319], 'found': [217], '42.1%': [219], '17.7%': [221], 'NSCLCs,': [223], 'respectively.': [224], 'frequency': [226], 'overexpression': [229, 260, 309, 318, 337], '(53.2%': [230], 'vs': [231, 240], '.': [232, 241], '28.1%,': [233], 'P': [234, 243, 269, 276, 284], '=': [235, 244, 277, 285], '0.002)': [236], '(25.2%': [239], '8.2%,': [242], '0.020)': [245], 'adenocarcinoma': [247], '(ADC),': [248], 'much': [250], 'higher': [251], 'than': [252], 'that': [253, 336], 'squamous': [255], 'cell': [256], '(SCC).': [258], 'associated': [262, 342], 'closely': [263], 'with': [264, 310, 343], 'ascending': [265], 'pN': [266], '(': [268, 275, 283], '<': [270], '0.001),': [271], 'advanced': [272], 'clinical': [273], 'stage': [274], '0.001)': [278, 286], 'tumor': [280, 344], 'distant': [281, 329], 'metastasis': [282, 330, 345], 'ADCs,': [288], 'but': [289], 'not': [290], 'SCCs.': [292], 'For': [293], 'whole': [295], 'cohort': [296], 'ADC': [298, 363], 'patients,': [299], 'univariate': [300], 'survival': [301, 327], 'analysis': [302], 'a': [304, 322, 353], 'significant': [305], 'association': [306], 'shortened': [311], 'survival;': [312], 'multivariate': [315], 'analysis,': [316], 'evaluated': [320], 'independent': [323], 'predictor': [324], 'overall': [326], 'free': [331], 'survival.': [332], 'These': [333], 'results': [334], 'suggested': [335], 'is': [340], 'positively': [341], 'ADC,': [348], 'might': [350], 'serve': [351], 'novel': [354], 'biomarker': [356], 'potential': [358], 'therapeutic': [359], 'target': [360], 'patients.': [364]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2257796989', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-09T13:07:08.542890', 'created_date': '2016-06-24'}