Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2255609726', 'doi': None, 'title': 'Endoglin (CD105) is a useful marker for evaluating microvessel density and predicting prognosis in esophageal squamous cell carcinoma.', 'display_name': 'Endoglin (CD105) is a useful marker for evaluating microvessel density and predicting prognosis in esophageal squamous cell carcinoma.', 'publication_year': 2014, 'publication_date': '2014-07-01', 'ids': {'openalex': 'https://openalex.org/W2255609726', 'mag': '2255609726', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24982351'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24982351', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047962921', 'display_name': 'Toshihide Sakurai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Toshihide Sakurai', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103410791', 'display_name': 'Hiroshi Okumura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Okumura', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021893377', 'display_name': 'Masataka Matsumoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masataka Matsumoto', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049069416', 'display_name': 'Yasuto Uchikado', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasuto Uchikado', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065039468', 'display_name': 'Tetsuhiro Owaki', 'orcid': 'https://orcid.org/0000-0002-7394-2061'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsuhiro Owaki', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101860152', 'display_name': 'Yoshiaki Kita', 'orcid': 'https://orcid.org/0000-0003-1878-4520'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshiaki Kita', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050797501', 'display_name': 'Tetsuro Setoyama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsuro Setoyama', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009711450', 'display_name': 'Itaru Omoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Itaru Omoto', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045932447', 'display_name': 'Yuko Kijima', 'orcid': 'https://orcid.org/0000-0002-1305-5284'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuko Kijima', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085097900', 'display_name': 'Sumiya Ishigami', 'orcid': 'https://orcid.org/0000-0002-4300-2263'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sumiya Ishigami', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009972099', 'display_name': 'Hiroshi Kurahara', 'orcid': 'https://orcid.org/0000-0002-7735-9607'}, 'institutions': [{'id': 'https://openalex.org/I107139324', 'display_name': 'Kagoshima University', 'ror': 'https://ror.org/03ss88z23', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I107139324']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shoji Natsugoe', 'raw_affiliation_strings': ['Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan', 'institution_ids': ['https://openalex.org/I107139324']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.823, 'has_fulltext': False, 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.804887, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '34', 'issue': '7', 'first_page': '3431', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10422', 'display_name': 'Molecular Mechanisms of Angiogenesis and Vascular Function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10422', 'display_name': 'Molecular Mechanisms of Angiogenesis and Vascular Function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11469', 'display_name': 'Lymphangiogenesis in Cancer Metastasis and Disease', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/microvessel', 'display_name': 'Microvessel', 'score': 0.80846465}, {'id': 'https://openalex.org/keywords/cd31', 'display_name': 'CD31', 'score': 0.7961249}, {'id': 'https://openalex.org/keywords/endothelial-cell-behavior', 'display_name': 'endothelial cell behavior', 'score': 0.576474}, {'id': 'https://openalex.org/keywords/vascular-endothelial-growth-factor', 'display_name': 'Vascular Endothelial Growth Factor', 'score': 0.574914}, {'id': 'https://openalex.org/keywords/endothelial-progenitor-cells', 'display_name': 'endothelial progenitor cells', 'score': 0.543298}, {'id': 'https://openalex.org/keywords/cancer-cell-metabolism', 'display_name': 'Cancer Cell Metabolism', 'score': 0.502421}], 'concepts': [{'id': 'https://openalex.org/C6061869', 'wikidata': 'https://www.wikidata.org/wiki/Q18250377', 'display_name': 'Endoglin', 'level': 4, 'score': 0.9348485}, {'id': 'https://openalex.org/C2776436680', 'wikidata': 'https://www.wikidata.org/wiki/Q1632335', 'display_name': 'Microvessel', 'level': 3, 'score': 0.80846465}, {'id': 'https://openalex.org/C2778939058', 'wikidata': 'https://www.wikidata.org/wiki/Q4046167', 'display_name': 'CD31', 'level': 3, 'score': 0.7961249}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.65207744}, {'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.62641925}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.48541126}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.4824339}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.42269453}, {'id': 'https://openalex.org/C2777025900', 'wikidata': 'https://www.wikidata.org/wiki/Q29725', 'display_name': 'Vascular endothelial growth factor', 'level': 3, 'score': 0.41624156}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.29724798}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2875396}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.22722611}, {'id': 'https://openalex.org/C167734588', 'wikidata': 'https://www.wikidata.org/wiki/Q4356503', 'display_name': 'VEGF receptors', 'level': 2, 'score': 0.12146267}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.08725712}, {'id': 'https://openalex.org/C10205521', 'wikidata': 'https://www.wikidata.org/wiki/Q4035578', 'display_name': 'CD34', 'level': 3, 'score': 0.08229673}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': True}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D000071063', 'descriptor_name': 'Endoglin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D000077277', 'descriptor_name': 'Esophageal Squamous Cell Carcinoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015999', 'descriptor_name': 'Multivariate Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009389', 'descriptor_name': 'Neovascularization, Pathologic', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D019408', 'descriptor_name': 'Platelet Endothelial Cell Adhesion Molecule-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019408', 'descriptor_name': 'Platelet Endothelial Cell Adhesion Molecule-1', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011956', 'descriptor_name': 'Receptors, Cell Surface', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24982351', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1536690700', 'https://openalex.org/W1583926224', 'https://openalex.org/W1590052782', 'https://openalex.org/W1595219556', 'https://openalex.org/W1903322008', 'https://openalex.org/W193511566', 'https://openalex.org/W1938627666', 'https://openalex.org/W1973146225', 'https://openalex.org/W1973217355', 'https://openalex.org/W1985036748', 'https://openalex.org/W1988978946', 'https://openalex.org/W1996141843', 'https://openalex.org/W1997676364', 'https://openalex.org/W2002700490', 'https://openalex.org/W2009095379', 'https://openalex.org/W2037761545', 'https://openalex.org/W2045667486', 'https://openalex.org/W2047283411', 'https://openalex.org/W2062797927', 'https://openalex.org/W2069547811', 'https://openalex.org/W2070948021', 'https://openalex.org/W2071874817', 'https://openalex.org/W2097021798', 'https://openalex.org/W2118402419', 'https://openalex.org/W2319962899', 'https://openalex.org/W2337737811', 'https://openalex.org/W2409949589', 'https://openalex.org/W2417451976'], 'related_works': ['https://openalex.org/W2363210815', 'https://openalex.org/W2151106513', 'https://openalex.org/W2124218970', 'https://openalex.org/W2094301362', 'https://openalex.org/W2090001808', 'https://openalex.org/W2074019258', 'https://openalex.org/W2045400655', 'https://openalex.org/W2043315819', 'https://openalex.org/W2033614003', 'https://openalex.org/W1981643311'], 'abstract_inverted_index': {'Angiogenic': [0], 'molecular': [1], 'markers': [2], 'such': [3], 'as': [4], 'vascular': [5, 45], 'endothelial': [6, 25, 46], 'growth': [7, 47], 'factor': [8], 'and': [9, 44, 66, 90, 129], 'tumor': [10, 77, 79], 'microvessel': [11, 32, 71, 104, 120, 122], 'density': [12, 33, 61, 72, 123], 'reflect': [13], 'prognosis': [14, 109, 130], 'of': [15, 24, 127], 'human': [16], 'cancers.': [17], 'The': [18], 'present': [19], 'study': [20], 'clarified': [21], 'the': [22, 125], 'usefulness': [23], 'marker': [26], 'endoglin': [27], '(CD': [28], '105)': [29], 'by': [30], 'assessing': [31], 'in': [34, 51, 112, 131], 'esophageal': [35, 53, 134], 'squamous': [36, 54, 135], 'cell': [37, 55, 136], 'carcinoma': [38, 56], '(ESCC).We': [39], 'immunohistochemically': [40], 'investigated': [41], 'CD105,': [42, 119], 'CD31,': [43], 'factor-A': [48], 'VEGF-A': [49, 91], 'expression': [50], 'primary': [52], 'specimens': [57], 'from': [58], '142': [59], 'patients.Microvessel': [60], 'was': [62, 73, 100, 110], '35.9±21.2': [63], 'for': [64, 68], 'CD105': [65, 70], '46.3±25.4': [67], 'CD31.': [69], 'significantly': [74, 107], 'associated': [75], 'with': [76, 95, 114, 133], 'length,': [78], 'invasion': [80], 'depth,': [81], 'lymph': [82], 'node': [83], 'metastasis,': [84], 'stage,': [85], 'lymphatic': [86], 'invasion,': [87, 89], 'venous': [88], 'expression;': [92], 'its': [93], 'correlation': [94], 'almost': [96], 'all': [97], 'clinicopathological': [98], 'parameters': [99], 'stronger': [101], 'than': [102], 'CD31': [103], 'density.': [105], 'And': [106], 'better': [108], 'achieved': [111], 'patients': [113, 132], 'low,': [115], 'compared': [116], 'to': [117], 'high': [118], 'density.CD105': [121], 'reflected': [124], 'degree': [126], 'angiogenesis': [128], 'carcinoma.': [137]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2255609726', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-09-14T10:48:55.100233', 'created_date': '2016-06-24'}