Publication Information

{'id': 'https://openalex.org/W2254315199', 'doi': 'https://doi.org/10.1152/ajprenal.1982.242.6.f575', 'title': 'In vivo proximal tubular fluid-to-plasma chloride concentration gradient in the rabbit', 'display_name': 'In vivo proximal tubular fluid-to-plasma chloride concentration gradient in the rabbit', 'publication_year': 1982, 'publication_date': '1982-06-01', 'ids': {'openalex': 'https://openalex.org/W2254315199', 'doi': 'https://doi.org/10.1152/ajprenal.1982.242.6.f575', 'mag': '2254315199', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7091312'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajprenal.1982.242.6.f575', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S200780590', 'display_name': 'AJP Renal Physiology', 'issn_l': '1522-1466', 'issn': ['1522-1466', '1931-857X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320261', 'host_organization_name': 'American Physical Society', 'host_organization_lineage': ['https://openalex.org/P4310320261'], 'host_organization_lineage_names': ['American Physical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037190779', 'display_name': 'Richard C. Vari', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'R. C. Vari', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113671728', 'display_name': 'C. E. Ott', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'C. E. Ott', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.392513, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 70, 'max': 72}, 'biblio': {'volume': '242', 'issue': '6', 'first_page': 'F575', 'last_page': 'F579'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10724', 'display_name': 'Ion Transport and Channel Regulation', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10724', 'display_name': 'Ion Transport and Channel Regulation', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tubule', 'display_name': 'Tubule', 'score': 0.80931836}, {'id': 'https://openalex.org/keywords/convoluted-tubule', 'display_name': 'Convoluted tubule', 'score': 0.6408778}, {'id': 'https://openalex.org/keywords/tubular-fluid', 'display_name': 'Tubular fluid', 'score': 0.5533851}, {'id': 'https://openalex.org/keywords/concentration-gradient', 'display_name': 'Concentration gradient', 'score': 0.46679315}, {'id': 'https://openalex.org/keywords/lumen', 'display_name': 'Lumen (anatomy)', 'score': 0.41534945}], 'concepts': [{'id': 'https://openalex.org/C2780498532', 'wikidata': 'https://www.wikidata.org/wiki/Q7850941', 'display_name': 'Tubule', 'level': 3, 'score': 0.80931836}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.7977394}, {'id': 'https://openalex.org/C56906281', 'wikidata': 'https://www.wikidata.org/wiki/Q4391435', 'display_name': 'Reabsorption', 'level': 3, 'score': 0.7587959}, {'id': 'https://openalex.org/C2781231759', 'wikidata': 'https://www.wikidata.org/wiki/Q58184', 'display_name': 'Nephron', 'level': 3, 'score': 0.7373363}, {'id': 'https://openalex.org/C2780222010', 'wikidata': 'https://www.wikidata.org/wiki/Q2916078', 'display_name': 'Proximal tubule', 'level': 3, 'score': 0.7159107}, {'id': 'https://openalex.org/C2779010597', 'wikidata': 'https://www.wikidata.org/wiki/Q5166601', 'display_name': 'Convoluted tubule', 'level': 3, 'score': 0.6408778}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.6342925}, {'id': 'https://openalex.org/C2778695967', 'wikidata': 'https://www.wikidata.org/wiki/Q44791900', 'display_name': 'Chloride', 'level': 2, 'score': 0.632244}, {'id': 'https://openalex.org/C2779742124', 'wikidata': 'https://www.wikidata.org/wiki/Q201552', 'display_name': 'Inulin', 'level': 2, 'score': 0.60334724}, {'id': 'https://openalex.org/C2778437025', 'wikidata': 'https://www.wikidata.org/wiki/Q7850936', 'display_name': 'Tubular fluid', 'level': 4, 'score': 0.5533851}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.47002932}, {'id': 'https://openalex.org/C3018453882', 'wikidata': 'https://www.wikidata.org/wiki/Q17104113', 'display_name': 'Concentration gradient', 'level': 2, 'score': 0.46679315}, {'id': 'https://openalex.org/C537181965', 'wikidata': 'https://www.wikidata.org/wiki/Q658', 'display_name': 'Sodium', 'level': 2, 'score': 0.4171414}, {'id': 'https://openalex.org/C131631996', 'wikidata': 'https://www.wikidata.org/wiki/Q1141325', 'display_name': 'Lumen (anatomy)', 'level': 2, 'score': 0.41534945}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.35590237}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3056522}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29456267}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.2756142}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2460759}, {'id': 'https://openalex.org/C159641895', 'wikidata': 'https://www.wikidata.org/wiki/Q108377937', 'display_name': 'Renal function', 'level': 2, 'score': 0.22709283}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.11554876}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001826', 'descriptor_name': 'Body Fluids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007687', 'descriptor_name': 'Kidney Tubules, Proximal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000042', 'descriptor_name': 'Absorption', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001639', 'descriptor_name': 'Bicarbonates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001639', 'descriptor_name': 'Bicarbonates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001826', 'descriptor_name': 'Body Fluids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D005919', 'descriptor_name': 'Glomerular Filtration Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007444', 'descriptor_name': 'Inulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007444', 'descriptor_name': 'Inulin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': False}, {'descriptor_ui': 'D007687', 'descriptor_name': 'Kidney Tubules, Proximal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012039', 'descriptor_name': 'Regional Blood Flow', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajprenal.1982.242.6.f575', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S200780590', 'display_name': 'AJP Renal Physiology', 'issn_l': '1522-1466', 'issn': ['1522-1466', '1931-857X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320261', 'host_organization_name': 'American Physical Society', 'host_organization_lineage': ['https://openalex.org/P4310320261'], 'host_organization_lineage_names': ['American Physical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7091312', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2419066528', 'https://openalex.org/W2408032074', 'https://openalex.org/W2254315199', 'https://openalex.org/W2220624253', 'https://openalex.org/W2176342191', 'https://openalex.org/W2170544496', 'https://openalex.org/W2075094551', 'https://openalex.org/W1993413886', 'https://openalex.org/W170923239', 'https://openalex.org/W1017446918'], 'abstract_inverted_index': {'It': [0], 'has': [1], 'been': [2], 'reported': [3], 'that': [4, 16, 157, 174], 'the': [5, 10, 25, 33, 48, 56, 75, 98, 149, 166, 172], 'concentration': [6, 62, 79, 113, 162], 'of': [7, 24, 47, 171], 'chloride': [8, 61, 96, 112, 161], 'in': [9, 17, 19, 32, 42, 54, 165, 167], 'proximal': [11, 34, 45, 58, 69, 87, 169, 184], 'tubule': [12, 35, 59, 70, 76, 159, 170, 185], 'is': [13, 36, 175, 180], 'greater': [14], 'than': [15], 'plasma': [18, 111], 'several': [20], 'mammalian': [21], 'species.': [22], 'Much': [23], 'theory': [26], 'concerning': [27], 'fluid': [28], 'and': [29, 65, 91, 95, 151, 179], 'electrolyte': [30], 'reabsorption': [31], 'based': [37], 'on': [38], 'data': [39], 'taken': [40], 'from': [41, 139], 'vitro': [43], 'isolated': [44], 'tubules': [46, 88], 'rabbit': [49, 57, 173], 'nephron.': [50], 'This': [51, 154], 'study': [52, 155], 'measured': [53, 101], 'vivo': [55, 168], 'fluid-to-ultrafiltrate': [60], 'ratio': [63, 80, 130], '[(TF/UF)Cl]': [64], 'its': [66], 'relationship': [67], 'to': [68], 'length': [71], 'as': [72], 'estimated': [73], 'by': [74, 102, 109], 'fluid-to-plasma': [77], 'inulin': [78, 94], '[(TF/P)In].': [81], 'From': [82], 'six': [83], 'rabbits,': [84], '19': [85], 'random': [86], 'were': [89], 'micropunctured': [90], 'analyzed': [92], 'for': [93, 114], 'concentrations,': [97], 'latter': [99], 'being': [100], 'microelectrometric': [103], 'titration.': [104], 'Plasma': [105], 'ultrafiltrate': [106], 'was': [107, 123, 131, 136], 'determined': [108], 'correcting': [110], 'protein': [115], 'concentration.': [116], 'The': [117, 128], 'average': [118], 'single': [119], 'nephron': [120], 'filtration': [121], 'rate': [122], '20.2': [124], '+/-': [125, 133], '0.8': [126], 'nl/min.': [127], '(TF/UF)Cl': [129], '1.10': [132], '0.03,': [134], 'which': [135], 'significantly': [137], 'different': [138], 'unity.': [140], 'Furthermore,': [141], 'regression': [142], 'analysis': [143], 'yielded': [144], 'no': [145], 'significant': [146], 'correlation': [147], 'between': [148], '(TF/UF(Cl': [150], '(TF/P)In': [152], 'ratio.': [153], 'demonstrates': [156], 'a': [158], 'lumen-to-plasma': [160], 'gradient': [163], 'exists': [164], 'apparently': [176], 'established': [177], 'early': [178], 'not': [181], 'correlated': [182], 'with': [183], 'length.': [186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2254315199', 'counts_by_year': [{'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-08T23:56:06.470431', 'created_date': '2016-06-24'}