Interleukin-6 production by cultured peripheral blood monocytes before and after stimulation by E. coli lipopolysaccharide in Iranian patients with aggressive periodontitis.

Name: Work Video:
Duration: 3 min 30 s
Mahboobeh N. Bajestan; Mehrdad Radvar; Jalil Tavakol Afshari; Mohammad R. Naseh; Hamid Reza Arab
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Afshari', 'raw_affiliation_strings': ['Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.;'], 'affiliations': [{'raw_affiliation_string': 'Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.;', 'institution_ids': ['https://openalex.org/I165560825']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086967827', 'display_name': 'Mohammad R. Naseh', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165560825', 'display_name': 'Mashhad University of Medical Sciences', 'ror': 'https://ror.org/04sfka033', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I165560825']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Mohammad R. Naseh', 'raw_affiliation_strings': ['Periodontology Department, School of Dentistry and Mashhad Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran'], 'affiliations': [{'raw_affiliation_string': 'Periodontology Department, School of Dentistry and Mashhad Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran', 'institution_ids': ['https://openalex.org/I165560825']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111841146', 'display_name': 'Hamid Reza Arab', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165560825', 'display_name': 'Mashhad University of Medical Sciences', 'ror': 'https://ror.org/04sfka033', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I165560825']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Hamid R. 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'https://openalex.org/T10257', 'display_name': 'Oral microbiology and periodontitis research', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/3506', 'display_name': 'Periodontics'}, 'field': {'id': 'https://openalex.org/fields/35', 'display_name': 'Dentistry'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10257', 'display_name': 'Oral microbiology and periodontitis research', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/3506', 'display_name': 'Periodontics'}, 'field': {'id': 'https://openalex.org/fields/35', 'display_name': 'Dentistry'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9923, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11452', 'display_name': 'Oral Health Pathology and Treatment', 'score': 0.9833, 'subfield': {'id': 'https://openalex.org/subfields/3506', 'display_name': 'Periodontics'}, 'field': {'id': 'https://openalex.org/fields/35', 'display_name': 'Dentistry'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/monocyte', 'display_name': 'Monocyte', 'score': 0.6683535}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.64794374}], 'concepts': [{'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.9023349}, {'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.84567857}, {'id': 'https://openalex.org/C2781184567', 'wikidata': 'https://www.wikidata.org/wiki/Q107244', 'display_name': 'Monocyte', 'level': 2, 'score': 0.6683535}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.64794374}, {'id': 'https://openalex.org/C2780385504', 'wikidata': 'https://www.wikidata.org/wiki/Q520127', 'display_name': 'Periodontitis', 'level': 2, 'score': 0.6180362}, {'id': 'https://openalex.org/C137061746', 'wikidata': 'https://www.wikidata.org/wiki/Q736033', 'display_name': 'Peripheral blood mononuclear cell', 'level': 3, 'score': 0.5097048}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4626755}, {'id': 'https://openalex.org/C126322002', 'wikidata': 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137, 149, 162], 'pro-inflammatory': [28], 'cytokines,': [29], 'may': [30, 207], 'have': [31], 'a': [32, 79, 190, 209, 233, 237], 'role': [33, 211], 'in': [34, 61, 78, 134, 151, 170, 186, 198, 201, 212], 'pathogenesis': [36, 214], 'aggressive': [38], 'periodontitis': [39], '(AP).': [40], 'To': [41], 'investigate': [42], 'this': [43, 178, 219], 'possibility,': [44], 'IL-6': [45, 100, 135, 148, 161, 165, 187], 'production': [46, 101, 136, 166, 188], 'by': [47, 56, 98, 110], 'cultured': [48], 'peripheral': [49, 87], 'blood': [50, 88], 'before': [52, 104, 138, 163], 'after': [54, 108, 167], 'stimulation': [55, 109, 140, 169, 194], 'E.': [57, 113], 'coli': [58], 'lipopolysaccharide': [59], '(LPS)': [60], 'AP': [62, 70, 229], 'patients': [63, 68, 142, 172, 199, 230], 'was': [64, 96, 130, 173, 179, 195], 'evaluated.': [65], 'MATERIAL/METHODS': [66], 'Fifteen': [67], 'with': [69, 73, 159], 'were': [71, 84, 122], 'compared': [72, 158], '15': [74], 'periodontally': [75], 'healthy': [76], 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