Title: EXPERIMENTAL STUDY ON THE GENESIS OF RADIATION HAZARD. II. INDUCED ANAEMIA
Abstract: On the basis of a hypothesis that a certain toxic substance was produced in the blood stream by x irradiation and caused secondary damage, the effect of blood irradiation in the test tube by x rays and Co/sup 6//sup 0/ gamma rays was studied after transfusion to healthy rabbits. When non-irradiated blood was transfused for 6 days, white and red cells and hemoglobin were increased; the degree of hemolysis was not altered and red cells with Heinz' bodies did not appear. However, after transfusion of the blood irradiated in the test tube with a dose of 3000 r, the red and white blood cells and hemoglobin were decreased, red cells including Heinz' bodies appeared, and the degree of hemolysis increased. These results suggested that some toxic substance was produced in the blood by irradiation and accelerated the secondary damage. The correlation between the function of RES and the appearance of the Heinz body in the blood was discussed. (Absts. Japan. Med., 1: No. 7,
Publication Year: 1959
Publication Date: 1959-01-01
Language: en
Type: article
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