Title: Uridine and Purine Nucleoside Phosphorylase Activity in Human and Rat Heart
Abstract: Literature data on cardiac pyrimidine metabolism are scarce, contrasting our knowledge on myocardial purine metabolism. However, degradation of pyrimidine nucleotides in the ischemic myocardium seems to parallel catabolism of adenylates1. More knowledge about pyrimidine nucleotide breakdown is useful because of 1) the regulatory role of pyrimidine derivatives2; 2) the interconversions of anticancer drugs by pyrimidine metabolizing enzymes3,4; 3) the potential diagnostic value of pyrimidine catabolites.
Publication Year: 1991
Publication Date: 1991-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 2
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