Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2221458218', 'doi': 'https://doi.org/10.1016/j.yrtph.2015.05.011', 'title': 'Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?', 'display_name': 'Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?', 'publication_year': 2015, 'publication_date': '2015-07-01', 'ids': {'openalex': 'https://openalex.org/W2221458218', 'doi': 'https://doi.org/10.1016/j.yrtph.2015.05.011', 'mag': '2221458218', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25985715'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.yrtph.2015.05.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S87719511', 'display_name': 'Regulatory Toxicology and Pharmacology', 'issn_l': '0273-2300', 'issn': ['0273-2300', '1096-0295'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5079798675', 'display_name': 'Hoi Y. Tong', 'orcid': 'https://orcid.org/0000-0003-2397-8274'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}, {'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Hoi Y. Tong', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025109488', 'display_name': 'Nicolás Medrano', 'orcid': 'https://orcid.org/0000-0003-2204-9609'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}, {'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Nicolás Medrano', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003525440', 'display_name': 'Alberto M. Borobia', 'orcid': 'https://orcid.org/0000-0002-8584-3263'}, 'institutions': [{'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}, {'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Alberto M. Borobia', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I63634437', 'https://openalex.org/I2800562746']}, {'raw_affiliation_string': 'General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082047957', 'display_name': 'Ana María Malalana Martínez', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Ana M. Martínez', 'raw_affiliation_strings': ['General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068845035', 'display_name': 'Julia Martín', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Julia Martín', 'raw_affiliation_strings': ['Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101616449', 'display_name': 'José Domínguez', 'orcid': 'https://orcid.org/0000-0002-5987-3717'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'José A. Ruiz', 'raw_affiliation_strings': ['Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018398132', 'display_name': 'Santos García', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Santos García', 'raw_affiliation_strings': ['Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Paediatric Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034176838', 'display_name': 'Manuel Quintana', 'orcid': 'https://orcid.org/0000-0003-0288-9088'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Manuel Quintana', 'raw_affiliation_strings': ['General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'General Emergency Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069496269', 'display_name': 'Antonio J. Carcas', 'orcid': 'https://orcid.org/0000-0003-1823-4174'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}, {'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Antonio J. Carcas', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010688434', 'display_name': 'Jesús Frías', 'orcid': 'https://orcid.org/0000-0001-9538-9677'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}, {'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Jesús Frías', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5065347223', 'display_name': 'Elena Ramı́rez', 'orcid': 'https://orcid.org/0000-0002-4052-8876'}, 'institutions': [{'id': 'https://openalex.org/I2800562746', 'display_name': 'Hospital Universitario La Paz', 'ror': 'https://ror.org/01s1q0w69', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800562746']}, {'id': 'https://openalex.org/I63634437', 'display_name': 'Autonomous University of Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': True, 'raw_author_name': 'Elena Ramírez', 'raw_affiliation_strings': ['Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacology, Hospital Universitario La Paz, IdiPAZ, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain', 'institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5065347223'], 'corresponding_institution_ids': ['https://openalex.org/I2800562746', 'https://openalex.org/I63634437'], 'apc_list': {'value': 3800, 'currency': 'USD', 'value_usd': 3800, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.291, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.891985, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '72', 'issue': '2', 'first_page': '370', 'last_page': '378'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11465', 'display_name': 'Mechanisms of Drug-Induced Hepatotoxicity', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11465', 'display_name': 'Mechanisms of Drug-Induced Hepatotoxicity', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11635', 'display_name': 'Management of Poisoning and Toxic Exposures', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2711', 'display_name': 'Emergency Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10337', 'display_name': 'Liver Cirrhosis and Associated Complications', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/acetaminophen', 'display_name': 'Acetaminophen', 'score': 0.70007885}, {'id': 'https://openalex.org/keywords/hepatotoxicity', 'display_name': 'Hepatotoxicity', 'score': 0.58278}, {'id': 'https://openalex.org/keywords/drug-overdose', 'display_name': 'Drug overdose', 'score': 0.44441903}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.90891826}, {'id': 'https://openalex.org/C2778722691', 'wikidata': 'https://www.wikidata.org/wiki/Q57055', 'display_name': 'Acetaminophen', 'level': 2, 'score': 0.70007885}, {'id': 'https://openalex.org/C61511704', 'wikidata': 'https://www.wikidata.org/wiki/Q1671857', 'display_name': 'Incidence (geometry)', 'level': 2, 'score': 0.6285432}, {'id': 'https://openalex.org/C2780724011', 'wikidata': 'https://www.wikidata.org/wiki/Q1295316', 'display_name': 'Emergency department', 'level': 2, 'score': 0.61505556}, {'id': 'https://openalex.org/C193230392', 'wikidata': 'https://www.wikidata.org/wiki/Q1663054', 'display_name': 'Ingestion', 'level': 2, 'score': 0.45406032}, {'id': 'https://openalex.org/C2776315796', 'wikidata': 'https://www.wikidata.org/wiki/Q3505252', 'display_name': 'Drug overdose', 'level': 3, 'score': 0.44441903}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42501456}, {'id': 'https://openalex.org/C167135981', 'wikidata': 'https://www.wikidata.org/wiki/Q2146302', 'display_name': 'Retrospective cohort study', 'level': 2, 'score': 0.4166988}, {'id': 'https://openalex.org/C194828623', 'wikidata': 'https://www.wikidata.org/wiki/Q2861470', 'display_name': 'Emergency medicine', 'level': 1, 'score': 0.391722}, {'id': 'https://openalex.org/C3017944768', 'wikidata': 'https://www.wikidata.org/wiki/Q1450463', 'display_name': 'Poison control', 'level': 2, 'score': 0.37489888}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.28743857}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000082', 'descriptor_name': 'Acetaminophen', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D018712', 'descriptor_name': 'Analgesics, Non-Narcotic', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D062787', 'descriptor_name': 'Drug Overdose', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D000082', 'descriptor_name': 'Acetaminophen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018712', 'descriptor_name': 'Analgesics, Non-Narcotic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002947', 'descriptor_name': 'Cities', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D002947', 'descriptor_name': 'Cities', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062787', 'descriptor_name': 'Drug Overdose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062787', 'descriptor_name': 'Drug Overdose', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D004636', 'descriptor_name': 'Emergency Service, Hospital', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004636', 'descriptor_name': 'Emergency Service, Hospital', 'qualifier_ui': 'Q000639', 'qualifier_name': 'trends', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015994', 'descriptor_name': 'Incidence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013030', 'descriptor_name': 'Spain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013030', 'descriptor_name': 'Spain', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D062606', 'descriptor_name': 'Tertiary Care Centers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062606', 'descriptor_name': 'Tertiary Care Centers', 'qualifier_ui': 'Q000639', 'qualifier_name': 'trends', 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.yrtph.2015.05.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S87719511', 'display_name': 'Regulatory Toxicology and Pharmacology', 'issn_l': '0273-2300', 'issn': ['0273-2300', '1096-0295'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25985715', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.86, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W117340944', 'https://openalex.org/W1527876010', 'https://openalex.org/W1571920011', 'https://openalex.org/W1578639372', 'https://openalex.org/W1608215573', 'https://openalex.org/W1885143646', 'https://openalex.org/W1967704312', 'https://openalex.org/W1967842522', 'https://openalex.org/W1977585558', 'https://openalex.org/W1990719252', 'https://openalex.org/W1998686416', 'https://openalex.org/W1999452365', 'https://openalex.org/W2000066924', 'https://openalex.org/W2000598330', 'https://openalex.org/W2004737355', 'https://openalex.org/W2013054179', 'https://openalex.org/W2024936080', 'https://openalex.org/W2041231288', 'https://openalex.org/W2052316595', 'https://openalex.org/W2054079077', 'https://openalex.org/W2056390046', 'https://openalex.org/W2060588027', 'https://openalex.org/W2065084078', 'https://openalex.org/W2067570070', 'https://openalex.org/W2082230457', 'https://openalex.org/W2083655254', 'https://openalex.org/W2085523430', 'https://openalex.org/W2092890981', 'https://openalex.org/W2093982770', 'https://openalex.org/W2097991696', 'https://openalex.org/W2104947000', 'https://openalex.org/W2106529258', 'https://openalex.org/W2106637799', 'https://openalex.org/W2113136638', 'https://openalex.org/W2132059072', 'https://openalex.org/W2133044793', 'https://openalex.org/W2134114403', 'https://openalex.org/W2138833181', 'https://openalex.org/W2144660367', 'https://openalex.org/W2145147082', 'https://openalex.org/W2148954026', 'https://openalex.org/W2155167335', 'https://openalex.org/W2160051020', 'https://openalex.org/W2160736876', 'https://openalex.org/W2163790438', 'https://openalex.org/W2166539778', 'https://openalex.org/W2171720135', 'https://openalex.org/W2213143551', 'https://openalex.org/W2324500761', 'https://openalex.org/W2333107025', 'https://openalex.org/W2407250454', 'https://openalex.org/W2409800341', 'https://openalex.org/W4242140134', 'https://openalex.org/W4323018901'], 'related_works': ['https://openalex.org/W4323536984', 'https://openalex.org/W3179483567', 'https://openalex.org/W2557476864', 'https://openalex.org/W2540307484', 'https://openalex.org/W2403285209', 'https://openalex.org/W2398206205', 'https://openalex.org/W2283872564', 'https://openalex.org/W2157315391', 'https://openalex.org/W2133508478', 'https://openalex.org/W2123340027'], 'abstract_inverted_index': {'Paracetamol': [0], '(Acetaminophen)': [1], 'poisoning': [2, 11, 55, 89, 115, 138, 143, 155], 'data': [3], 'can': [4], 'reveal': [5], 'the': [6, 27, 62, 148, 170], 'potential': [7], 'deficiencies': [8], 'of': [9, 20, 31, 53, 83, 98, 108, 150, 153, 163, 172, 196], 'paracetamol': [10, 42, 48, 54, 114, 154, 173, 186], 'management': [12], 'guidelines.': [13], 'We': [14, 145], 'conducted': [15], 'a': [16, 32, 193], 'retrospective': [17], 'cohort': [18], 'study': [19], 'patients': [21, 51, 72, 85, 110], '>18years': [22], 'who': [23, 45], 'were': [24, 56, 174], 'attended': [25], 'in': [26, 61, 73, 79], 'emergency': [28], 'department': [29], '(ED)': [30], 'Spanish': [33], 'tertiary': [34], 'hospital,': [35], 'from': [36, 65], '2005': [37, 74], 'to': [38, 75, 130, 176], '2010': [39], 'for': [40, 136, 141, 199], 'suspected': [41, 52, 151], 'overdose': [43], 'and': [44, 121, 139, 189], 'had': [46], 'measurable': [47], 'concentrations.': [49], '208': [50], 'identified.': [57], 'The': [58, 127, 161], 'annual': [59], 'incidence': [60, 149], 'ED': [63], 'increased': [64], '2.0': [66], '(95%-CI:': [67, 77], '0.2-7.2)': [68], 'cases': [69, 152], 'per': [70], '10,000': [71], '3.4': [76], '1.1-8.8)': [78], '2010.': [80], 'Only': [81], '7': [82], '98': [84], '(7.14%)': [86], 'with': [87, 112, 124, 169], 'acute': [88, 101, 137], 'at': [90, 116, 156], 'toxic': [91, 117], 'doses': [92, 118], 'showed': [93], 'hepatotoxicity': [94, 120], 'signs,': [95], '4': [96], '(57.1%)': [97], 'whom': [99], 'presented': [100, 119], 'liver': [102], 'failure': [103], '(ALF)': [104], 'criteria,': [105], 'while': [106], '8': [107], '10': [109], '(80%)': [111], 'chronic': [113, 142, 177, 187], '3': [122], '(37.5%)': [123], 'ALF': [125], 'criteria.': [126], 'time': [128], 'required': [129], 'find': [131], 'medical': [132], 'care': [133], 'was': [134], '9.0h': [135], '49.6h': [140], '(p<0.001).': [144], 'conclude': [146], 'that': [147], 'our': [157], 'hospital': [158], 'is': [159], 'increasing.': [160], 'majority': [162], 'toxicity': [164], 'cases,': [165], 'including': [166], 'ALF,': [167], 'associated': [168], 'ingestion': [171], 'due': [175], 'poisoning.': [178], 'This': [179], 'finding': [180], 'constitutes': [181], 'an': [182], 'important': [183], 'warning': [184], 'regarding': [185], 'poisoning,': [188], 'clinicians': [190], 'should': [191], 'have': [192], 'higher': [194], 'index': [195], 'clinical': [197], 'suspicion': [198], 'this': [200], 'entity.': [201]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2221458218', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-09-11T16:44:10.568395', 'created_date': '2016-06-24'}