Title: Effects of certain CNS depressants and verapamil on cGMP in the cerebellum of rats.
Abstract:The influence, individually and in combination, of certain general CNS depressants, Ca+2, A23187, and verapamil on rat cerebellar cGMP was studied. When Ca+2 was given to rats treated with ethanol, et...The influence, individually and in combination, of certain general CNS depressants, Ca+2, A23187, and verapamil on rat cerebellar cGMP was studied. When Ca+2 was given to rats treated with ethanol, ether, or pentobarbital a minor increase in cGMP resulted. However, A23187 alone, or with Ca+2 did not produce a rise in cGMP levels in the presence of those drugs. A similar effect was seen with verapamil. Increasing doses of pentobarbital with verapamil enhanced the inhibition of cGMP.Read More
Publication Year: 1985
Publication Date: 1985-11-01
Language: en
Type: article
Indexed In: ['pubmed']
Access and Citation
Cited By Count: 3
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