Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2213100191', 'doi': 'https://doi.org/10.1007/978-1-61779-225-0_4', 'title': 'Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells', 'display_name': 'Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W2213100191', 'doi': 'https://doi.org/10.1007/978-1-61779-225-0_4', 'mag': '2213100191'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/978-1-61779-225-0_4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463399', 'display_name': 'Humana Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'book-chapter', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5064384359', 'display_name': 'Lyle Armstrong', 'orcid': 'https://orcid.org/0000-0002-7234-9362'}, 'institutions': [{'id': 'https://openalex.org/I2802983449', 'display_name': 'Centre for Life', 'ror': 'https://ror.org/027tbp210', 'country_code': 'GB', 'type': 'other', 'lineage': ['https://openalex.org/I2802983449']}, {'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'Lyle Armstrong', 'raw_affiliation_strings': ['Institute of Human Genetics, Newcastle University, The International Centre for Life, Central Parkway, Newcastle Upon Tyne, NE1 3BZ, UK'], 'affiliations': [{'raw_affiliation_string': 'Institute of Human Genetics, Newcastle University, The International Centre for Life, Central Parkway, Newcastle Upon Tyne, NE1 3BZ, UK', 'institution_ids': ['https://openalex.org/I2802983449', 'https://openalex.org/I84884186']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5032539966', 'display_name': 'Majlinda Lako', 'orcid': 'https://orcid.org/0000-0003-1327-8573'}, 'institutions': [{'id': 'https://openalex.org/I2802983449', 'display_name': 'Centre for Life', 'ror': 'https://ror.org/027tbp210', 'country_code': 'GB', 'type': 'other', 'lineage': ['https://openalex.org/I2802983449']}, {'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Majlinda Lako', 'raw_affiliation_strings': ['Institute of Human Genetics, Newcastle University, The International Centre for Life, Newcastle Upon Tyne, UK'], 'affiliations': [{'raw_affiliation_string': 'Institute of Human Genetics, Newcastle University, The International Centre for Life, Newcastle Upon Tyne, UK', 'institution_ids': ['https://openalex.org/I2802983449', 'https://openalex.org/I84884186']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5064384359'], 'corresponding_institution_ids': ['https://openalex.org/I2802983449', 'https://openalex.org/I84884186'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': None, 'issue': None, 'first_page': '25', 'last_page': '44'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10878', 'display_name': 'CRISPR and Genetic Engineering', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/reprogramming', 'display_name': 'Reprogramming', 'score': 0.9697916}, {'id': 'https://openalex.org/keywords/cell-potency', 'display_name': 'Cell potency', 'score': 0.5557882}, {'id': 'https://openalex.org/keywords/epigenesis', 'display_name': 'Epigenesis', 'score': 0.49346414}], 'concepts': [{'id': 'https://openalex.org/C77255625', 'wikidata': 'https://www.wikidata.org/wiki/Q402093', 'display_name': 'Reprogramming', 'level': 3, 'score': 0.9697916}, {'id': 'https://openalex.org/C134305767', 'wikidata': 'https://www.wikidata.org/wiki/Q725508', 'display_name': 'Somatic cell', 'level': 3, 'score': 0.8954178}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.76474494}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6462376}, {'id': 'https://openalex.org/C107459253', 'wikidata': 'https://www.wikidata.org/wiki/Q674925', 'display_name': 'Induced pluripotent stem cell', 'level': 4, 'score': 0.6381293}, {'id': 'https://openalex.org/C27390768', 'wikidata': 'https://www.wikidata.org/wiki/Q862600', 'display_name': 'Cell potency', 'level': 5, 'score': 0.5557882}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.55152893}, {'id': 'https://openalex.org/C202438428', 'wikidata': 'https://www.wikidata.org/wiki/Q1939923', 'display_name': 'Somatic cell nuclear transfer', 'level': 5, 'score': 0.5079184}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.50120497}, {'id': 'https://openalex.org/C179463898', 'wikidata': 'https://www.wikidata.org/wiki/Q10273301', 'display_name': 'Epigenesis', 'level': 5, 'score': 0.49346414}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.42643356}, {'id': 'https://openalex.org/C148738053', 'wikidata': 'https://www.wikidata.org/wiki/Q210861', 'display_name': 'Cellular differentiation', 'level': 3, 'score': 0.42459232}, {'id': 'https://openalex.org/C2780258238', 'wikidata': 'https://www.wikidata.org/wiki/Q2520842', 'display_name': 'Germ', 'level': 2, 'score': 0.41933492}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.3542845}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.34185752}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.21361515}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.20961657}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.18195859}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.063528895}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.04939255}, {'id': 'https://openalex.org/C2778177303', 'wikidata': 'https://www.wikidata.org/wiki/Q227717', 'display_name': 'Blastocyst', 'level': 4, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/978-1-61779-225-0_4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463399', 'display_name': 'Humana Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 99, 'referenced_works': ['https://openalex.org/W1480800427', 'https://openalex.org/W1506835737', 'https://openalex.org/W1522206353', 'https://openalex.org/W1599093384', 'https://openalex.org/W1603508604', 'https://openalex.org/W1657289287', 'https://openalex.org/W1691916884', 'https://openalex.org/W1707745162', 'https://openalex.org/W1821797507', 'https://openalex.org/W1829371983', 'https://openalex.org/W1967282907', 'https://openalex.org/W1968263601', 'https://openalex.org/W1968767056', 'https://openalex.org/W1968931043', 'https://openalex.org/W1969015262', 'https://openalex.org/W1970159856', 'https://openalex.org/W1970953423', 'https://openalex.org/W1971400148', 'https://openalex.org/W1971647523', 'https://openalex.org/W1973727308', 'https://openalex.org/W1978140644', 'https://openalex.org/W1978173381', 'https://openalex.org/W1978493564', 'https://openalex.org/W1979011239', 'https://openalex.org/W1979200139', 'https://openalex.org/W1980537562', 'https://openalex.org/W1980738706', 'https://openalex.org/W1981186364', 'https://openalex.org/W1982674658', 'https://openalex.org/W1982840871', 'https://openalex.org/W1986877892', 'https://openalex.org/W1992525863', 'https://openalex.org/W1992653847', 'https://openalex.org/W1992964809', 'https://openalex.org/W1999452037', 'https://openalex.org/W2002179012', 'https://openalex.org/W2004196170', 'https://openalex.org/W2004457665', 'https://openalex.org/W2005437050', 'https://openalex.org/W2009619710', 'https://openalex.org/W2014428651', 'https://openalex.org/W2016127328', 'https://openalex.org/W2016137472', 'https://openalex.org/W2016196074', 'https://openalex.org/W2025000509', 'https://openalex.org/W2026529460', 'https://openalex.org/W2026805786', 'https://openalex.org/W2030596457', 'https://openalex.org/W2036636377', 'https://openalex.org/W2037525608', 'https://openalex.org/W2039159207', 'https://openalex.org/W2039551265', 'https://openalex.org/W2043178104', 'https://openalex.org/W2043193936', 'https://openalex.org/W2050032705', 'https://openalex.org/W2052865953', 'https://openalex.org/W2054521968', 'https://openalex.org/W2055129041', 'https://openalex.org/W2056069396', 'https://openalex.org/W2061331718', 'https://openalex.org/W2063006038', 'https://openalex.org/W2069772488', 'https://openalex.org/W2072230758', 'https://openalex.org/W2072431484', 'https://openalex.org/W2077890483', 'https://openalex.org/W2079679058', 'https://openalex.org/W2084162879', 'https://openalex.org/W2086989609', 'https://openalex.org/W2089252344', 'https://openalex.org/W2090510808', 'https://openalex.org/W2091414779', 'https://openalex.org/W2092668546', 'https://openalex.org/W2095417588', 'https://openalex.org/W2099177650', 'https://openalex.org/W2099189400', 'https://openalex.org/W2102085606', 'https://openalex.org/W2105718307', 'https://openalex.org/W2106921118', 'https://openalex.org/W2107038650', 'https://openalex.org/W2113496309', 'https://openalex.org/W2115438557', 'https://openalex.org/W2122029913', 'https://openalex.org/W2128368952', 'https://openalex.org/W2131278882', 'https://openalex.org/W2134015142', 'https://openalex.org/W2134985597', 'https://openalex.org/W2135925928', 'https://openalex.org/W2137812576', 'https://openalex.org/W2139384923', 'https://openalex.org/W2142046859', 'https://openalex.org/W2145160468', 'https://openalex.org/W2148612336', 'https://openalex.org/W2152589171', 'https://openalex.org/W2161098391', 'https://openalex.org/W2161224111', 'https://openalex.org/W2163763156', 'https://openalex.org/W2164012688', 'https://openalex.org/W2310269042', 'https://openalex.org/W3144666244'], 'related_works': ['https://openalex.org/W4249704861', 'https://openalex.org/W3156911831', 'https://openalex.org/W3129026263', 'https://openalex.org/W3011232459', 'https://openalex.org/W2926306485', 'https://openalex.org/W2802634706', 'https://openalex.org/W2036320504', 'https://openalex.org/W2027075234', 'https://openalex.org/W1969839288', 'https://openalex.org/W1859616466'], 'abstract_inverted_index': {'There': [0], 'are': [1, 41], 'few': [2, 73], 'circumstances': [3], 'in': [4, 69], 'which': [5, 54], 'the': [6, 34, 51, 75], 'phenotype': [7], 'of': [8, 36, 44, 64, 74, 77], 'differentiated': [9, 66], 'cells': [10, 40], 'generated': [11], 'during': [12], 'normal': [13], 'embryonic': [14], 'development': [15], 'can': [16], 'revert': [17], 'to': [18, 60, 71], 'a': [19, 65, 72], 'less': [20], 'developed': [21], 'or': [22], 'more': [23, 32], 'developmentally': [24], 'plastic': [25], 'state.': [26], 'Somatic': [27], 'cell': [28, 68], 'nuclear': [29], 'transfer': [30], 'and': [31, 48], 'recently': [33], 'derivation': [35], 'induced': [37], 'pluripotent': [38], 'stem': [39], 'two': [42], 'examples': [43], 'this': [45], 'rare': [46], 'phenomenon': [47], 'we': [49], 'discuss': [50], 'mechanisms': [52], 'by': [53], 'these': [55, 78], 'techniques': [56], 'may': [57], 'be': [58], 'able': [59], 'effect': [61], 'epigenetic': [62], 'reprogramming': [63], 'somatic': [67], 'addition': [70], 'shortcomings': [76], 'techniques.': [79]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2213100191', 'counts_by_year': [], 'updated_date': '2024-12-13T18:53:09.856012', 'created_date': '2016-06-24'}