Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis

Name: Work Video:
Duration: 3 min 30 s
Description: Background and Aims:Ulcerative colitis [UC] is associated with colonic mucosa barrier defects and bacterial dysbiosis, but these features may simply be the result of inflammation. Therefore, we sought to assess whether these features are inherently abrogated in the terminal ileum [TI] of UC patients, where inflammation is absent.
Misagh Alipour; Deenaz Zaidi; Rosica Valcheva; Juan Jovel; Inés Martínez; Consolato Sergi; Jens Walter; Andrew L. Mason; Gane Ka‐Shu Wong; Levinus A. Dieleman; Matthew Carroll; Hien Q. Huynh; Eytan Wine
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