Title: Enantiopure <i>N</i>‐Benzyloxycarbonyl‐β<sup>2</sup>‐amino Acid Allyl Esters from Racemic β‐Lactams by Dynamic Kinetic Resolution using <i>Candida antarctica</i> Lipase B
Abstract:Abstract The dynamic kinetic resolution of α‐substituted racemic β‐lactams by alcoholytic ring‐opening, catalyzed by immobilized lipase B from Candida antarctica is described. With this process, a var...Abstract The dynamic kinetic resolution of α‐substituted racemic β‐lactams by alcoholytic ring‐opening, catalyzed by immobilized lipase B from Candida antarctica is described. With this process, a variety of racemic α‐substituted N ‐Cbz‐azetidinones (Cbz=benzyloxycarbonyl) was transformed to the corresponding N ‐Cbz‐protected β 2 ‐amino acid allyl esters with high enantioselectivity (up to 99%) and high yields (up to quantitative) at room temperature. magnified imageRead More
Publication Year: 2015
Publication Date: 2015-12-17
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 13
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot
Title: $Enantiopure <i>N</i>‐Benzyloxycarbonyl‐β<sup>2</sup>‐amino Acid Allyl Esters from Racemic β‐Lactams by Dynamic Kinetic Resolution using <i>Candida antarctica</i> Lipase B
Abstract: Abstract The dynamic kinetic resolution of α‐substituted racemic β‐lactams by alcoholytic ring‐opening, catalyzed by immobilized lipase B from Candida antarctica is described. With this process, a variety of racemic α‐substituted N ‐Cbz‐azetidinones (Cbz=benzyloxycarbonyl) was transformed to the corresponding N ‐Cbz‐protected β 2 ‐amino acid allyl esters with high enantioselectivity (up to 99%) and high yields (up to quantitative) at room temperature. magnified image