Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2201522906', 'doi': 'https://doi.org/10.1152/jappl.1997.83.5.1420', 'title': 'Dynamic properties of lung parenchyma: mechanical contributions of fiber network and interstitial cells', 'display_name': 'Dynamic properties of lung parenchyma: mechanical contributions of fiber network and interstitial cells', 'publication_year': 1997, 'publication_date': '1997-11-01', 'ids': {'openalex': 'https://openalex.org/W2201522906', 'doi': 'https://doi.org/10.1152/jappl.1997.83.5.1420', 'mag': '2201522906', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9375301'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/jappl.1997.83.5.1420', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S140889577', 'display_name': 'Journal of Applied Physiology', 'issn_l': '1522-1601', 'issn': ['1522-1601', '8750-7587'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050913166', 'display_name': 'Huichin Yuan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Huichin Yuan', 'raw_affiliation_strings': ['Department of Biomedical Engineering, Boston University, and'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Engineering, Boston University, and', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109808270', 'display_name': 'Edward P. Ingenito', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Edward P. Ingenito', 'raw_affiliation_strings': ["Brigham and Women's Hospital, Boston, Massachusetts 02215"], 'affiliations': [{'raw_affiliation_string': "Brigham and Women's Hospital, Boston, Massachusetts 02215", 'institution_ids': ['https://openalex.org/I1283280774']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045629242', 'display_name': 'Bélâ Suki', 'orcid': 'https://orcid.org/0000-0002-9720-1006'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Béla Suki', 'raw_affiliation_strings': ['Department of Biomedical Engineering, Boston University, and'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Engineering, Boston University, and', 'institution_ids': ['https://openalex.org/I111088046']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.524, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 131, 'citation_normalized_percentile': {'value': 0.999911, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '83', 'issue': '5', 'first_page': '1420', 'last_page': '1431'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11366', 'display_name': 'Elasticity and Material Modeling', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11366', 'display_name': 'Elasticity and Material Modeling', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11372', 'display_name': 'Hydraulic and Pneumatic Systems', 'score': 0.9539, 'subfield': {'id': 'https://openalex.org/subfields/2210', 'display_name': 'Mechanical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11778', 'display_name': 'Electrical and Bioimpedance Tomography', 'score': 0.9514, 'subfield': {'id': 'https://openalex.org/subfields/2208', 'display_name': 'Electrical and Electronic Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/parenchyma', 'display_name': 'Parenchyma', 'score': 0.6466003}, {'id': 'https://openalex.org/keywords/strain', 'display_name': 'Strain (injury)', 'score': 0.42547515}, {'id': 'https://openalex.org/keywords/interstitial-cell', 'display_name': 'Interstitial cell', 'score': 0.41778105}], 'concepts': [{'id': 'https://openalex.org/C196822366', 'wikidata': 'https://www.wikidata.org/wiki/Q270524', 'display_name': 'Parenchyma', 'level': 2, 'score': 0.6466003}, {'id': 'https://openalex.org/C518705261', 'wikidata': 'https://www.wikidata.org/wiki/Q25615', 'display_name': 'Connective tissue', 'level': 2, 'score': 0.60858405}, {'id': 'https://openalex.org/C519885992', 'wikidata': 'https://www.wikidata.org/wiki/Q161', 'display_name': 'Fiber', 'level': 2, 'score': 0.51041096}, {'id': 'https://openalex.org/C186541917', 'wikidata': 'https://www.wikidata.org/wiki/Q910483', 'display_name': 'Viscoelasticity', 'level': 2, 'score': 0.45521045}, {'id': 'https://openalex.org/C2778022156', 'wikidata': 'https://www.wikidata.org/wiki/Q576145', 'display_name': 'Strain (injury)', 'level': 2, 'score': 0.42547515}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.4180432}, {'id': 'https://openalex.org/C2777534427', 'wikidata': 'https://www.wikidata.org/wiki/Q6057165', 'display_name': 'Interstitial cell', 'level': 2, 'score': 0.41778105}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.4155873}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.39019987}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.33420908}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.24787009}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2138929}, {'id': 'https://openalex.org/C159985019', 'wikidata': 'https://www.wikidata.org/wiki/Q181790', 'display_name': 'Composite material', 'level': 1, 'score': 0.19064823}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.13398594}], 'mesh': [{'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D018485', 'descriptor_name': 'Muscle Fibers, Skeletal', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001696', 'descriptor_name': 'Biomechanical Phenomena', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003238', 'descriptor_name': 'Connective Tissue', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003238', 'descriptor_name': 'Connective Tissue', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D003238', 'descriptor_name': 'Connective Tissue', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003239', 'descriptor_name': 'Connective Tissue Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003239', 'descriptor_name': 'Connective Tissue Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004548', 'descriptor_name': 'Elasticity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006168', 'descriptor_name': 'Guinea Pigs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016210', 'descriptor_name': 'Methacholine Chloride', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016210', 'descriptor_name': 'Methacholine Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018485', 'descriptor_name': 'Muscle Fibers, Skeletal', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D018485', 'descriptor_name': 'Muscle Fibers, Skeletal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018485', 'descriptor_name': 'Muscle Fibers, Skeletal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010277', 'descriptor_name': 'Parasympathomimetics', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010277', 'descriptor_name': 'Parasympathomimetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014783', 'descriptor_name': 'Viscosity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/jappl.1997.83.5.1420', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S140889577', 'display_name': 'Journal of Applied Physiology', 'issn_l': '1522-1601', 'issn': ['1522-1601', '8750-7587'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320155', 'host_organization_name': 'American Physiological Society', 'host_organization_lineage': ['https://openalex.org/P4310320155'], 'host_organization_lineage_names': ['American Physiological Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9375301', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1524122329', 'https://openalex.org/W1556356032', 'https://openalex.org/W1774151066', 'https://openalex.org/W1885862114', 'https://openalex.org/W1908556531', 'https://openalex.org/W1911795667', 'https://openalex.org/W1953165844', 'https://openalex.org/W1953370205', 'https://openalex.org/W1963548830', 'https://openalex.org/W1969158263', 'https://openalex.org/W1975163121', 'https://openalex.org/W1979443566', 'https://openalex.org/W1980255174', 'https://openalex.org/W1982595669', 'https://openalex.org/W2007924064', 'https://openalex.org/W2009263098', 'https://openalex.org/W2038007375', 'https://openalex.org/W2054734105', 'https://openalex.org/W2057331175', 'https://openalex.org/W2073794566', 'https://openalex.org/W2075514521', 'https://openalex.org/W2088713513', 'https://openalex.org/W2094542138', 'https://openalex.org/W2097246107', 'https://openalex.org/W2097253466', 'https://openalex.org/W2121199401', 'https://openalex.org/W2123167484', 'https://openalex.org/W2132011458', 'https://openalex.org/W2140690080', 'https://openalex.org/W2143645698', 'https://openalex.org/W2147481147', 'https://openalex.org/W2169314828', 'https://openalex.org/W2174182048', 'https://openalex.org/W2180290358', 'https://openalex.org/W2180325046', 'https://openalex.org/W2180503361', 'https://openalex.org/W2185948560', 'https://openalex.org/W2231655233', 'https://openalex.org/W2254828765', 'https://openalex.org/W2255920711', 'https://openalex.org/W2283597429', 'https://openalex.org/W2339255964', 'https://openalex.org/W2408477343', 'https://openalex.org/W2412390500', 'https://openalex.org/W2463387901', 'https://openalex.org/W34720912', 'https://openalex.org/W570645159'], 'related_works': ['https://openalex.org/W807319463', 'https://openalex.org/W4293192718', 'https://openalex.org/W4243019676', 'https://openalex.org/W4221057967', 'https://openalex.org/W2783562378', 'https://openalex.org/W2517352629', 'https://openalex.org/W2395256833', 'https://openalex.org/W2255703620', 'https://openalex.org/W2045876794', 'https://openalex.org/W2040929039'], 'abstract_inverted_index': {'Yuan,': [0], 'Huichin,': [1], 'Edward': [2], 'P.': [3], 'Ingenito,': [4], 'and': [5, 17, 35, 60, 88, 103, 106, 112, 114, 140, 145, 154, 157, 163, 173, 179, 181, 190, 200, 205], 'Béla': [6], 'Suki.Dynamic': [7], 'properties': [8], 'of': [9, 14, 29, 48, 74, 91, 101, 109, 152, 219, 248], 'lung': [10], 'parenchyma:': [11], 'mechanical': [12], 'contributions': [13, 28], 'fiber': [15, 33], 'network': [16, 34, 229], 'interstitial': [18, 36, 93, 249], 'cells.': [19, 94, 250], 'J.': [20], 'Appl.': [21], 'Physiol.': [22], '83(5):': [23], '1420–1431,': [24], '1997.—We': [25], 'investigated': [26], 'the': [27, 30, 57, 92, 121, 150, 171, 198, 213, 226, 236, 244], 'connective': [31, 227], 'tissue': [32, 137, 228], 'cells': [37], 'to': [38, 79, 217], 'parenchymal': [39, 233], 'mechanics': [40, 234], 'in': [41, 120, 197, 212, 235], 'a': [42, 70, 131], 'surfactant-free': [43], 'system.': [44], 'In': [45], 'eight': [46], 'strips': [47], 'uniform': [49], 'dimension': [50], 'from': [51, 77], 'guinea': [52], 'pig': [53], 'lung,': [54, 238], 'we': [55], 'assessed': [56], 'storage': [58], '(G′)': [59], 'loss': [61], '(G”)': [62], 'moduli': [63], 'by': [64, 184, 243], 'using': [65, 130], 'pseudorandom': [66], 'length': [67], 'oscillations': [68], 'containing': [69], 'specially': [71], 'designed': [72], 'set': [73], 'seven': [75], 'frequencies': [76], '0.07': [78], '2.4': [80], 'Hz': [81], 'at': [82, 98], 'baseline,': [83], 'during': [84], 'methacholine': [85], '(MCh)': [86], 'challenge,': [87, 170], 'after': [89], 'death': [90], 'Measurements': [95], 'were': [96, 115, 128, 176, 194, 209], 'made': [97], 'mean': [99, 165, 191], 'forces': [100], '0.5': [102], '1': [104], 'g': [105], 'strain': [107, 161, 188], 'amplitudes': [108], '5,': [110], '10,': [111], '15%': [113], 'repeated': [116], '12': [117], 'h': [118], 'later': [119], 'same,': [122], 'but': [123], 'nonviable': [124, 201, 214], 'samples.': [125, 202], 'The': [126, 143, 203], 'results': [127], 'interpreted': [129], 'linear': [132], 'viscoelastic': [133], 'model': [134], 'incorporating': [135], 'both': [136, 155], 'damping': [138], '(G)': [139], 'stiffness': [141], '(H).': [142], 'G′': [144, 172], 'G”': [146, 174], 'increased': [147, 183], 'linearly': [148], 'with': [149], 'logarithm': [151], 'frequency,': [153], 'G': [156, 180, 204], 'H': [158, 182], 'showed': [159], 'negative': [160], 'amplitude': [162], 'positive': [164], 'force': [166, 192], 'dependence.': [167], 'After': [168], 'MCh': [169], 'spectra': [175], 'elevated': [177], 'uniformly,': [178], '<15%.': [185], 'Tissue': [186], 'stiffness,': [187], 'amplitude,': [189], 'dependence': [193], 'virtually': [195], 'identical': [196], 'viable': [199], 'hence': [206], 'energy': [207], 'dissipation': [208], '∼10%': [210], 'smaller': [211], 'samples': [215], 'due': [216], 'absence': [218], 'actin-myosin': [220], 'cross-bridge': [221], 'cycling.': [222], 'We': [223], 'conclude': [224], 'that': [225], 'may': [230], 'also': [231], 'dominate': [232], 'intact': [237], 'which': [239], 'can': [240], 'be': [241], 'influenced': [242], 'tone': [245], 'or': [246], 'contraction': [247]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2201522906', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-13T17:55:20.895539', 'created_date': '2016-06-24'}