Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2201402669', 'doi': 'https://doi.org/10.1016/s1474-4422(15)00332-4', 'title': "Accelerating stem cell trials for Alzheimer's disease", 'display_name': "Accelerating stem cell trials for Alzheimer's disease", 'publication_year': 2016, 'publication_date': '2016-02-01', 'ids': {'openalex': 'https://openalex.org/W2201402669', 'doi': 'https://doi.org/10.1016/s1474-4422(15)00332-4', 'mag': '2201402669', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26704439'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1474-4422(15)00332-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S70053155', 'display_name': 'The Lancet Neurology', 'issn_l': '1474-4422', 'issn': ['1474-4422', '1474-4465'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017437542', 'display_name': 'Joshua Hunsberger', 'orcid': 'https://orcid.org/0000-0002-8683-6129'}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}, {'id': 'https://openalex.org/I100681346', 'display_name': 'Forest Institute', 'ror': 'https://ror.org/04fves619', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I100681346']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joshua G Hunsberger', 'raw_affiliation_strings': ['Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA'], 'affiliations': [{'raw_affiliation_string': 'Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA', 'institution_ids': ['https://openalex.org/I47251452', 'https://openalex.org/I100681346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103522535', 'display_name': 'Mahendra S. Rao', 'orcid': 'https://orcid.org/0000-0003-0768-1155'}, 'institutions': [{'id': 'https://openalex.org/I2801610018', 'display_name': 'New York Stem Cell Foundation', 'ror': 'https://ror.org/03n2a3p06', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801610018']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mahendra Rao', 'raw_affiliation_strings': ['New York Stem Cell Foundation, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'New York Stem Cell Foundation, New York, NY, USA', 'institution_ids': ['https://openalex.org/I2801610018']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060384074', 'display_name': 'Joanne Kurtzberg', 'orcid': 'https://orcid.org/0000-0002-3370-0703'}, 'institutions': [{'id': 'https://openalex.org/I4210153043', 'display_name': 'Duke University Hospital', 'ror': 'https://ror.org/04bct7p84', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876', 'https://openalex.org/I4210153043']}, {'id': 'https://openalex.org/I4210126298', 'display_name': 'Duke Medical Center', 'ror': 'https://ror.org/03njmea73', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joanne Kurtzberg', 'raw_affiliation_strings': ['Robertson Clinical and Translational Cell Therapy Program, Duke University Medical Center, Durham, NC, USA'], 'affiliations': [{'raw_affiliation_string': 'Robertson Clinical and Translational Cell Therapy Program, Duke University Medical Center, Durham, NC, USA', 'institution_ids': ['https://openalex.org/I4210153043', 'https://openalex.org/I4210126298']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028758394', 'display_name': 'Jeff W. M. Bulte', 'orcid': 'https://orcid.org/0000-0003-1202-1610'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jeff W M Bulte', 'raw_affiliation_strings': ['Department of Radiology and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046942201', 'display_name': 'Anthony Atala', 'orcid': 'https://orcid.org/0000-0001-8186-2160'}, 'institutions': [{'id': 'https://openalex.org/I47251452', 'display_name': 'Wake Forest University', 'ror': 'https://ror.org/0207ad724', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I47251452']}, {'id': 'https://openalex.org/I100681346', 'display_name': 'Forest Institute', 'ror': 'https://ror.org/04fves619', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I100681346']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony Atala', 'raw_affiliation_strings': ['Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA'], 'affiliations': [{'raw_affiliation_string': 'Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA', 'institution_ids': ['https://openalex.org/I47251452', 'https://openalex.org/I100681346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026487650', 'display_name': 'Frank M. LaFerla', 'orcid': 'https://orcid.org/0000-0003-2324-6911'}, 'institutions': [{'id': 'https://openalex.org/I204250578', 'display_name': 'University of California, Irvine', 'ror': 'https://ror.org/04gyf1771', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204250578']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Frank M LaFerla', 'raw_affiliation_strings': ['Institute for Memory Impairment and Neurological Disorders, University of California-Irvine, Irvine, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Institute for Memory Impairment and Neurological Disorders, University of California-Irvine, Irvine, CA, USA', 'institution_ids': ['https://openalex.org/I204250578']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025828500', 'display_name': 'Henry T. Greely', 'orcid': 'https://orcid.org/0000-0002-1105-6734'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Henry T Greely', 'raw_affiliation_strings': ['Center for Law and the Biosciences, Stanford University, Stanford, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Center for Law and the Biosciences, Stanford University, Stanford, CA, USA', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069018183', 'display_name': 'Akira Sawa', 'orcid': 'https://orcid.org/0000-0003-1401-3008'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Akira Sawa', 'raw_affiliation_strings': ['Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103144641', 'display_name': 'Sam Gandy', 'orcid': 'https://orcid.org/0000-0001-6455-4721'}, 'institutions': [{'id': 'https://openalex.org/I98704320', 'display_name': 'Icahn School of Medicine at Mount Sinai', 'ror': 'https://ror.org/04a9tmd77', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1320796813', 'https://openalex.org/I98704320']}, {'id': 'https://openalex.org/I4210116369', 'display_name': 'James J. Peters VA Medical Center', 'ror': 'https://ror.org/02c8hpe74', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210094901', 'https://openalex.org/I4210116369']}, {'id': 'https://openalex.org/I4210101308', 'display_name': 'NFL Foundation', 'ror': 'https://ror.org/01ahvm174', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210101308']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sam Gandy', 'raw_affiliation_strings': ['Center for Cognitive Health and National Football League Neurological Care, Icahn School of Medicine at Mount Sinai, New York, NY, USA', 'James J Peters VA Medical Center, Bronx, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Center for Cognitive Health and National Football League Neurological Care, Icahn School of Medicine at Mount Sinai, New York, NY, USA', 'institution_ids': ['https://openalex.org/I98704320', 'https://openalex.org/I4210101308']}, {'raw_affiliation_string': 'James J Peters VA Medical Center, Bronx, NY, USA', 'institution_ids': ['https://openalex.org/I4210116369']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059020389', 'display_name': 'Lon S. Schneider', 'orcid': 'https://orcid.org/0000-0002-4636-6150'}, 'institutions': [{'id': 'https://openalex.org/I1174212', 'display_name': 'University of Southern California', 'ror': 'https://ror.org/03taz7m60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1174212']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lon S Schneider', 'raw_affiliation_strings': ["Alzheimer's Disease Research Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA"], 'affiliations': [{'raw_affiliation_string': "Alzheimer's Disease Research Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA", 'institution_ids': ['https://openalex.org/I1174212']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5090774179', 'display_name': 'P. Murali Doraiswamy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170897317', 'display_name': 'Duke University', 'ror': 'https://ror.org/00py81415', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170897317']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'P Murali Doraiswamy', 'raw_affiliation_strings': ['Duke Institute for Brain Sciences, Duke University, Durham, NC, USA', 'Psychiatry Department, Duke University, Durham, NC, USA'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry Department, Duke University, Durham, NC, USA', 'institution_ids': ['https://openalex.org/I170897317']}, {'raw_affiliation_string': 'Duke Institute for Brain Sciences, Duke University, Durham, NC, USA', 'institution_ids': ['https://openalex.org/I170897317']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 14, 'corresponding_author_ids': ['https://openalex.org/A5090774179'], 'corresponding_institution_ids': ['https://openalex.org/I170897317'], 'apc_list': {'value': 6300, 'currency': 'USD', 'value_usd': 6300, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.662, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 86, 'citation_normalized_percentile': {'value': 0.999734, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '15', 'issue': '2', 'first_page': '219', 'last_page': '230'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10505', 'display_name': 'Induction and Differentiation of Pluripotent Stem Cells', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10505', 'display_name': 'Induction and Differentiation of Pluripotent Stem Cells', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13417', 'display_name': 'Regulation of Stem Cell Therapies and Clinics', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11953', 'display_name': 'Ethical Implications of Neuroenhancement Technologies', 'score': 0.966, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/induced-pluripotent-stem-cells', 'display_name': 'Induced Pluripotent Stem Cells', 'score': 0.517744}, {'id': 'https://openalex.org/keywords/pluripotent-stem-cells', 'display_name': 'Pluripotent Stem Cells', 'score': 0.50794}, {'id': 'https://openalex.org/keywords/stem-cell-regulation', 'display_name': 'Stem Cell Regulation', 'score': 0.506975}, {'id': 'https://openalex.org/keywords/drug-development', 'display_name': 'Drug development', 'score': 0.4813093}, {'id': 'https://openalex.org/keywords/drug-trial', 'display_name': 'Drug trial', 'score': 0.4637324}], 'concepts': [{'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.7700677}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.7022009}, {'id': 'https://openalex.org/C107459253', 'wikidata': 'https://www.wikidata.org/wiki/Q674925', 'display_name': 'Induced pluripotent stem cell', 'level': 4, 'score': 0.6671773}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6582701}, {'id': 'https://openalex.org/C3018890749', 'wikidata': 'https://www.wikidata.org/wiki/Q204711', 'display_name': 'Food and drug administration', 'level': 2, 'score': 0.6253934}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.5857108}, {'id': 'https://openalex.org/C198826908', 'wikidata': 'https://www.wikidata.org/wiki/Q1922379', 'display_name': 'Mesenchymal stem cell', 'level': 2, 'score': 0.49581942}, {'id': 'https://openalex.org/C64903051', 'wikidata': 'https://www.wikidata.org/wiki/Q2198549', 'display_name': 'Drug development', 'level': 3, 'score': 0.4813093}, {'id': 'https://openalex.org/C74187038', 'wikidata': 'https://www.wikidata.org/wiki/Q1418791', 'display_name': 'Drug discovery', 'level': 2, 'score': 0.47493818}, {'id': 'https://openalex.org/C2992672634', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Drug trial', 'level': 3, 'score': 0.4637324}, {'id': 'https://openalex.org/C2780035454', 'wikidata': 'https://www.wikidata.org/wiki/Q8386', 'display_name': 'Drug', 'level': 2, 'score': 0.458894}, {'id': 'https://openalex.org/C502032728', 'wikidata': 'https://www.wikidata.org/wiki/Q11081', 'display_name': "Alzheimer's disease", 'level': 3, 'score': 0.43869784}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.35419855}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.34134814}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.32816643}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.31235158}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19462672}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.19103822}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.16152894}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.14690083}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.13979408}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D057026', 'descriptor_name': 'Induced Pluripotent Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D045164', 'descriptor_name': 'Mesenchymal Stem Cell Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057026', 'descriptor_name': 'Induced Pluripotent Stem Cells', 'qualifier_ui': 'Q000637', 'qualifier_name': 'transplantation', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1474-4422(15)00332-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S70053155', 'display_name': 'The Lancet Neurology', 'issn_l': '1474-4422', 'issn': ['1474-4422', '1474-4465'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26704439', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.68, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 88, 'referenced_works': ['https://openalex.org/W1671213273', 'https://openalex.org/W1840177221', 'https://openalex.org/W1848995617', 'https://openalex.org/W1965571382', 'https://openalex.org/W1974012915', 'https://openalex.org/W1992932504', 'https://openalex.org/W1994377277', 'https://openalex.org/W1994397669', 'https://openalex.org/W1994891102', 'https://openalex.org/W1995002051', 'https://openalex.org/W2002650695', 'https://openalex.org/W2006708611', 'https://openalex.org/W2014750054', 'https://openalex.org/W2015617018', 'https://openalex.org/W2015735925', 'https://openalex.org/W2016193689', 'https://openalex.org/W2018274135', 'https://openalex.org/W2018508990', 'https://openalex.org/W2018827685', 'https://openalex.org/W2021311952', 'https://openalex.org/W2027908278', 'https://openalex.org/W2032694823', 'https://openalex.org/W2032979564', 'https://openalex.org/W2033032660', 'https://openalex.org/W2036603803', 'https://openalex.org/W2037877458', 'https://openalex.org/W2041891376', 'https://openalex.org/W2046371527', 'https://openalex.org/W2047135667', 'https://openalex.org/W2065561114', 'https://openalex.org/W2067036696', 'https://openalex.org/W2067064610', 'https://openalex.org/W2067079625', 'https://openalex.org/W2070789023', 'https://openalex.org/W2072271155', 'https://openalex.org/W2073162672', 'https://openalex.org/W2073252618', 'https://openalex.org/W2079378641', 'https://openalex.org/W2081661336', 'https://openalex.org/W2082682623', 'https://openalex.org/W2083922876', 'https://openalex.org/W2087738014', 'https://openalex.org/W2088714934', 'https://openalex.org/W2089216251', 'https://openalex.org/W2090986546', 'https://openalex.org/W2092041474', 'https://openalex.org/W2097085702', 'https://openalex.org/W2099150220', 'https://openalex.org/W2101687573', 'https://openalex.org/W2102769637', 'https://openalex.org/W2106585367', 'https://openalex.org/W2108869307', 'https://openalex.org/W2112579276', 'https://openalex.org/W2115745847', 'https://openalex.org/W2118097868', 'https://openalex.org/W2118935254', 'https://openalex.org/W2121414639', 'https://openalex.org/W2123466664', 'https://openalex.org/W2124490243', 'https://openalex.org/W2125987139', 'https://openalex.org/W2126231259', 'https://openalex.org/W2129497119', 'https://openalex.org/W2129530584', 'https://openalex.org/W2130749065', 'https://openalex.org/W2131108668', 'https://openalex.org/W2132013944', 'https://openalex.org/W2133693340', 'https://openalex.org/W2135782855', 'https://openalex.org/W2138574694', 'https://openalex.org/W2138848591', 'https://openalex.org/W2138977668', 'https://openalex.org/W2141823770', 'https://openalex.org/W2146249493', 'https://openalex.org/W2153019619', 'https://openalex.org/W2156969855', 'https://openalex.org/W2157073241', 'https://openalex.org/W2157494569', 'https://openalex.org/W2159123476', 'https://openalex.org/W2159124083', 'https://openalex.org/W2160694193', 'https://openalex.org/W2163224376', 'https://openalex.org/W2164384962', 'https://openalex.org/W2166622020', 'https://openalex.org/W2169802489', 'https://openalex.org/W2171050058', 'https://openalex.org/W2325761141', 'https://openalex.org/W239729453', 'https://openalex.org/W240733015'], 'related_works': ['https://openalex.org/W4387893576', 'https://openalex.org/W4244169196', 'https://openalex.org/W2764191054', 'https://openalex.org/W2520636634', 'https://openalex.org/W2375058649', 'https://openalex.org/W2127264463', 'https://openalex.org/W2126478593', 'https://openalex.org/W2118510076', 'https://openalex.org/W2107556826', 'https://openalex.org/W1993324100'], 'abstract_inverted_index': {'At': [0], 'present,': [1], 'no': [2], 'effective': [3, 15], 'cure': [4], 'or': [5, 108], 'prophylaxis': [6], 'exists': [7], 'for': [8, 68, 84, 123], "Alzheimer's": [9, 98, 139], 'disease.': [10, 140], 'Symptomatic': [11], 'treatments': [12, 137], 'are': [13, 105], 'modestly': [14], 'and': [16, 44, 49, 76, 113, 117, 135], 'offer': [17], 'only': [18], 'temporary': [19], 'benefit.': [20], 'Advances': [21], 'in': [22, 100, 111], 'induced': [23], 'pluripotent': [24], 'stem': [25, 94, 128], 'cell': [26, 62], '(iPSC)': [27], 'technology': [28], 'have': [29], 'the': [30, 73, 85, 101, 124, 133], 'potential': [31, 58, 136], 'to': [32, 40, 96], 'enable': [33, 54], 'development': [34], 'of': [35, 52, 57, 91, 126, 138], 'so-called': [36], 'disease-in-a-dish': [37], 'personalised': [38], 'models': [39], 'study': [41], 'disease': [42, 99], 'mechanisms': [43], 'reveal': [45], 'new': [46, 81], 'therapeutic': [47, 69], 'approaches,': [48], 'large': [50], 'panels': [51], 'iPSCs': [53], 'rapid': [55], 'screening': [56], 'drug': [59, 82], 'candidates.': [60], 'Different': [61], 'types': [63], 'can': [64], 'also': [65], 'be': [66], 'produced': [67], 'use.': [70], 'In': [71], '2015,': [72], 'US': [74], 'Food': [75], 'Drug': [77], 'Administration': [78], 'granted': [79], 'investigational': [80], 'approval': [83], 'first': [86], 'phase': [87], '2A': [88], 'clinical': [89], 'trial': [90], 'ischaemia-tolerant': [92], 'mesenchymal': [93], 'cells': [95], 'treat': [97], 'USA.': [102], 'Similar': [103], 'trials': [104], 'either': [106], 'underway': [107], 'being': [109], 'planned': [110], 'Europe': [112], 'Asia.': [114], 'Although': [115], 'safety': [116], 'ethical': [118], 'concerns': [119], 'remain,': [120], 'we': [121], 'call': [122], 'acceleration': [125], 'human': [127], 'cell-based': [129], 'translational': [130], 'research': [131], 'into': [132], 'causes': [134]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2201402669', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 9}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 12}], 'updated_date': '2024-09-11T16:40:06.006828', 'created_date': '2016-06-24'}