Molecular Design Based on 3D Pharmacophores. Applications to 5-HT<sub>7</sub> Receptors

Name: Work Video:
Duration: 3 min 30 s
Alban Lepailleur; Ronan Bureau; Stéphane Lemaître; François Dauphin; Jean‐Charles Lancelot; Vincent Contesse; Sébastien Lenglet; Catherine Delarue; Hubert Vaudry; Sylvain Rault
{'id': 'https://openalex.org/W2197392606', 'doi': 'https://doi.org/10.1021/ci030036l', 'title': 'Molecular Design Based on 3D Pharmacophores. Applications to 5-HT<sub>7</sub> Receptors', 'display_name': 'Molecular Design Based on 3D Pharmacophores. Applications to 5-HT<sub>7</sub> Receptors', 'publication_year': 2004, 'publication_date': '2004-04-22', 'ids': {'openalex': 'https://openalex.org/W2197392606', 'doi': 'https://doi.org/10.1021/ci030036l', 'mag': '2197392606', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15154784'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ci030036l', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171559003', 'display_name': 'Journal of Chemical Information and Computer Sciences', 'issn_l': '0095-2338', 'issn': ['0095-2338', '1520-5142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5075186187', 'display_name': 'Alban Lepailleur', 'orcid': 'https://orcid.org/0000-0003-0202-1588'}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alban Lepailleur', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091469186', 'display_name': 'Ronan Bureau', 'orcid': 'https://orcid.org/0000-0001-9404-8117'}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Ronan Bureau', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I4210105918', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078351664', 'display_name': 'Stéphane Lemaître', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}, {'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Stéphane Lemaître', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074973782', 'display_name': 'François Dauphin', 'orcid': 'https://orcid.org/0000-0002-0916-5536'}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'François Dauphin', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111725560', 'display_name': 'Jean‐Charles Lancelot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-Charles Lancelot', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077107948', 'display_name': 'Vincent Contesse', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Vincent Contesse', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008114310', 'display_name': 'Sébastien Lenglet', 'orcid': 'https://orcid.org/0000-0002-4853-8163'}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sébastien Lenglet', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073283183', 'display_name': 'Catherine Delarue', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Catherine Delarue', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105885862', 'display_name': 'Hubert Vaudry', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hubert Vaudry', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I62396329', 'https://openalex.org/I154526488', 'https://openalex.org/I4210105918']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113468466', 'display_name': 'Sylvain Rault', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I62396329', 'display_name': 'Université de Rouen Normandie', 'ror': 'https://ror.org/03nhjew95', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918', 'https://openalex.org/I62396329']}, {'id': 'https://openalex.org/I4210105918', 'display_name': 'Normandie Université', 'ror': 'https://ror.org/01k40cz91', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I4210105918']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sylvain Rault', 'raw_affiliation_strings': ["Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, 5 rue Vaubénard, 14032 Caen, and INSERM U413, IFRMP 23, Université de Rouen, 76821 Mont-Saint-Aignan, France", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I62396329', 'https://openalex.org/I4210105918']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.832, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 23, 'citation_normalized_percentile': {'value': 0.633607, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '44', 'issue': '3', 'first_page': '1148', 'last_page': '1152'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.95, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.95, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10908', 'display_name': 'Analytical Chemistry and Chromatography', 'score': 0.9388, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C56173144', 'wikidata': 'https://www.wikidata.org/wiki/Q1539893', 'display_name': 'Pharmacophore', 'level': 2, 'score': 0.9973172}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.44480476}, {'id': 'https://openalex.org/C21951064', 'wikidata': 'https://www.wikidata.org/wiki/Q899212', 'display_name': 'Combinatorial chemistry', 'level': 1, 'score': 0.41909203}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4039682}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.37633345}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.36253798}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14753935}], 'mesh': [{'descriptor_ui': 'D011985', 'descriptor_name': 'Receptors, Serotonin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011985', 'descriptor_name': 'Receptors, Serotonin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ci030036l', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171559003', 'display_name': 'Journal of Chemical Information and Computer Sciences', 'issn_l': '0095-2338', 'issn': ['0095-2338', '1520-5142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15154784', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W105910878', 'https://openalex.org/W1968654216', 'https://openalex.org/W1973108801', 'https://openalex.org/W1990339598', 'https://openalex.org/W2040667380', 'https://openalex.org/W2048277156', 'https://openalex.org/W2057394321', 'https://openalex.org/W2059057526', 'https://openalex.org/W2060606982', 'https://openalex.org/W2074492505', 'https://openalex.org/W2075651097', 'https://openalex.org/W2085754416', 'https://openalex.org/W2095054997', 'https://openalex.org/W2107341127', 'https://openalex.org/W2137266207', 'https://openalex.org/W2150458632', 'https://openalex.org/W2161634702', 'https://openalex.org/W2162166182', 'https://openalex.org/W2951962884', 'https://openalex.org/W3024123298', 'https://openalex.org/W3043419407'], 'related_works': ['https://openalex.org/W4391375266', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2770470780', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'A': [0, 24], 'definition': [1], 'of': [2, 18, 51, 55], 'a': [3, 52], 'pharmacophore': [4, 36], 'for': [5], 'the': [6, 14, 22, 31, 49], '5-HT7': [7, 57], 'antagonists': [8, 20], 'was': [9], 'carried': [10], 'out': [11], 'by': [12, 29], 'searching': [13], 'common': [15], 'chemical': [16], 'features': [17], 'selective': [19], 'from': [21], 'literature.': [23], 'molecular': [25], 'design': [26], 'is': [27], 'described': [28], 'analyzing': [30], 'differences': [32], 'between': [33], 'this': [34], 'new': [35, 53], 'and': [37], 'three': [38], 'other': [39], '3D': [40], 'serotonin': [41], 'pharmacophores': [42], 'previously': [43], 'described.': [44], 'This': [45], 'comparison': [46], 'led': [47], 'to': [48], 'synthesis': [50], 'series': [54], 'potent': [56], 'antagonists.': [58]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2197392606', 'counts_by_year': [{'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}], 'updated_date': '2025-01-03T12:05:05.671084', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
