Title: Evaluation of Antibacterial Activity of Piliostigma thonningiin (crude extract) and fractions 1-3, 4, 5, 6 and 7 against Methicillin-resistant Staphylococcus aureus (MRSA).
Abstract: Aim of this study is to investigate the antibacterial activity of traditional Nigeria medicines with special interest in anti-methicillin-resistant Staphylococcus aureus (MRSA) activity. Hexane, ethylacetate, methanol and aqueous extracts of this plant was prepared. Agar dilution, agar-well diffusion tests and MIC’s were used to investigate antibacterial activity. Out of 4 extract that were evaluated for antibacterial activity using agar dilution technique only hexane extract gave the highest inhibition against all the MRSA isolates. Crude extract and fractions showed the highest levels of antibacterial activity overall with MIC’s against MRSA in the range of 1.0 and 2.0mg/ml. The presence of antibacterial activity in extracts and fractions of leaves of P. thonningii plants traditionally used to treat skin infections, are reported for the first time. Extracts from P. thonningii, also used to
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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Cited By Count: 1
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