Publication Information

{'id': 'https://openalex.org/W2186048183', 'doi': None, 'title': 'Relationship between changes in the content of acetylcholine and the activities of acetylcholinesterase and choline acetyltransferase in the hippocampus of the rat after septal lesions.', 'display_name': 'Relationship between changes in the content of acetylcholine and the activities of acetylcholinesterase and choline acetyltransferase in the hippocampus of the rat after septal lesions.', 'publication_year': 1977, 'publication_date': '1977-01-01', 'ids': {'openalex': 'https://openalex.org/W2186048183', 'mag': '2186048183', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/899888'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/899888', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055373243', 'display_name': 'B Oderfeld-Nowak', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Barbara Oderfeld-Nowak', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082904897', 'display_name': 'Anna Potempska', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Anna Potempska', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.339, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.399545, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 56, 'max': 64}, 'biblio': {'volume': '37', 'issue': '3', 'first_page': '137', 'last_page': '49'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12023', 'display_name': 'Cholinesterase Inhibitors in Neurodegenerative Diseases', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12023', 'display_name': 'Cholinesterase Inhibitors in Neurodegenerative Diseases', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10448', 'display_name': 'Neural Mechanisms of Memory Formation and Spatial Navigation', 'score': 0.9738, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/choline', 'display_name': 'Choline', 'score': 0.69660044}, {'id': 'https://openalex.org/keywords/acetylcholinesterase', 'display_name': 'Acetylcholinesterase', 'score': 0.483971}, {'id': 'https://openalex.org/keywords/limiting', 'display_name': 'Limiting', 'score': 0.42329156}], 'concepts': [{'id': 'https://openalex.org/C198399640', 'wikidata': 'https://www.wikidata.org/wiki/Q14863671', 'display_name': 'Choline acetyltransferase', 'level': 3, 'score': 0.93320525}, {'id': 'https://openalex.org/C2778816929', 'wikidata': 'https://www.wikidata.org/wiki/Q22676679', 'display_name': 'Acetylcholinesterase', 'level': 3, 'score': 0.91621923}, {'id': 'https://openalex.org/C2775910092', 'wikidata': 'https://www.wikidata.org/wiki/Q180623', 'display_name': 'Acetylcholine', 'level': 2, 'score': 0.86028504}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.8021045}, {'id': 'https://openalex.org/C2779059548', 'wikidata': 'https://www.wikidata.org/wiki/Q383701', 'display_name': 'Aché', 'level': 4, 'score': 0.7564591}, {'id': 'https://openalex.org/C148762608', 'wikidata': 'https://www.wikidata.org/wiki/Q3748185', 'display_name': 'Hippocampal formation', 'level': 2, 'score': 0.7298634}, {'id': 'https://openalex.org/C2781123555', 'wikidata': 'https://www.wikidata.org/wiki/Q193166', 'display_name': 'Choline', 'level': 2, 'score': 0.69660044}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.61646444}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5434014}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5384325}, {'id': 'https://openalex.org/C22885893', 'wikidata': 'https://www.wikidata.org/wiki/Q4862743', 'display_name': 'Cholinergic', 'level': 2, 'score': 0.45170203}, {'id': 'https://openalex.org/C188198153', 'wikidata': 'https://www.wikidata.org/wiki/Q1613840', 'display_name': 'Limiting', 'level': 2, 'score': 0.42329156}, {'id': 'https://openalex.org/C2777411258', 'wikidata': 'https://www.wikidata.org/wiki/Q410546', 'display_name': 'Neostigmine', 'level': 2, 'score': 0.41714418}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.3770466}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.35623515}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25152218}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.15405396}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000110', 'descriptor_name': 'Acetylcholinesterase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002795', 'descriptor_name': 'Choline O-Acetyltransferase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D012688', 'descriptor_name': 'Septum Pellucidum', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000110', 'descriptor_name': 'Acetylcholinesterase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002795', 'descriptor_name': 'Choline O-Acetyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012688', 'descriptor_name': 'Septum Pellucidum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/899888', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1971048984', 'https://openalex.org/W1975814886', 'https://openalex.org/W1976976653', 'https://openalex.org/W1979771452', 'https://openalex.org/W1983662340', 'https://openalex.org/W1984835584', 'https://openalex.org/W1988165308', 'https://openalex.org/W1988240074', 'https://openalex.org/W1993309635', 'https://openalex.org/W2007722971', 'https://openalex.org/W2020602699', 'https://openalex.org/W2029118604', 'https://openalex.org/W2044385925', 'https://openalex.org/W2050342160', 'https://openalex.org/W2060468822', 'https://openalex.org/W2068161777', 'https://openalex.org/W2069929809', 'https://openalex.org/W2078190150', 'https://openalex.org/W2084582389', 'https://openalex.org/W2086897419', 'https://openalex.org/W2093560060', 'https://openalex.org/W2120924698', 'https://openalex.org/W2139214499', 'https://openalex.org/W2168534798', 'https://openalex.org/W2235550281', 'https://openalex.org/W2403035479', 'https://openalex.org/W2413801731', 'https://openalex.org/W2419234360', 'https://openalex.org/W2444153549', 'https://openalex.org/W3022279899', 'https://openalex.org/W47372031'], 'related_works': ['https://openalex.org/W2481025151', 'https://openalex.org/W2418699966', 'https://openalex.org/W2359901297', 'https://openalex.org/W2186048183', 'https://openalex.org/W2090995969', 'https://openalex.org/W2058104009', 'https://openalex.org/W2047916164', 'https://openalex.org/W1984118641', 'https://openalex.org/W193377221', 'https://openalex.org/W1002682648'], 'abstract_inverted_index': {'Changes': [0], 'in': [1, 13, 86, 109], 'acetylcholine': [2], '(ACh)': [3], 'content': [4, 111], 'and': [5, 8, 40, 75], 'acetylcholinesterase': [6], '(AChE)': [7], 'choline': [9, 101], 'acetyltransferase': [10], '(ChAc)': [11], 'activity': [12, 72], 'the': [14, 23, 34, 38, 50, 71, 79, 83, 87, 97], 'hippocampus': [15], 'were': [16], 'compared': [17], 'after': [18, 46, 55], 'various': [19], 'septal': [20], 'lesions.': [21], 'With': [22], 'use': [24], 'of': [25, 37, 49, 73, 82, 91, 100], 'a': [26], 'multiple': [27], 'regression': [28], 'model': [29], 'it': [30], 'was': [31], 'shown': [32], 'that': [33, 70], 'time': [35], 'course': [36], 'ACh': [39, 84, 110], 'enzymic': [41], 'level': [42, 85], 'changes': [43], 'is': [44, 77, 102], 'concordant': [45], 'total': [47], 'destruction': [48], 'septum,': [51], 'but': [52], 'not': [53, 78], 'always': [54], 'partial': [56], 'damage.': [57], 'Septal': [58], 'lesions': [59], 'produced': [60], 'an': [61, 106], 'effect': [62], 'mainly': [63], 'on': [64], 'bound': [65], 'ACh.': [66], 'The': [67, 89], 'results': [68], 'suggest': [69], 'AChE': [74], 'ChAc': [76], 'rate-limiting': [80], 'factor': [81], 'hippocampus.': [88], 'involvement': [90], 'other': [92], 'hippocampal': [93], 'neurotransmitters': [94], 'acting': [95], 'through': [96], 'high-affinity': [98], 'uptake': [99], 'supposed': [103], 'to': [104], 'play': [105], 'important': [107], 'role': [108], 'regulation.': [112]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2186048183', 'counts_by_year': [], 'updated_date': '2024-09-14T04:52:40.381225', 'created_date': '2016-06-24'}