Title: Blood transfusion and intensive care 2A05 3C00
Abstract: Blood transfusion as a therapy was first proposed in the 17th century, with Sir Christopher Wren in England performing a range of animal-to-animal transfusions and Jean-Baptiste Denis in Paris performing animal-to-human transfusions. 1 These led to a series of fatal reactions and unsurprisingly resulted in the prohibition of blood transfusion as a therapy in England and France. The next support for blood transfusion arose in the 19th century, initially from John Leacock in 1816 and subsequently James Blundell, an obstetrician from Guy’s Hospital in London, who reported favourably on the benefit of transfusion in cases of post-partum haemorrhage in 1828. However, blood transfusion remained a dangerous and risky therapy for patients, particularly due to transfusion reactions. 1 During a career of over 40 years, Karl Landsteiner described the blood types A, B and O, as well as other important aspects of blood immunochemistry including the Rhesus system. In the latter half of the 20th century, Robert Race and Ruth Sanger extended knowledge about the blood group system.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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