Title: Studies on In vitro Antioxidant, Antibacterial and Insecticidal Activity of Methanolic Extract of Abrus pulchellus Wall (Fabaceae)
Abstract: Abrus pulchellus Wall is a twinning shrub belonging to the family Fabaceae. The present investigation was carried to evaluate antioxidant, antibacterial and insecticidal potential of different concentrations of methanolic extract of A. pulchellus leaves. DPPH radical scavenging assay and Fe reducing +3 assay were carried to determine antioxidant activity of extract. Insecticidal efficacy of extract was tested using second instar larvae of Aedes aegypti. The extract exhibited marked antioxidant activity by scavenging DPPH free radical in a concentration dependent manner. In Fe reducing assay, increase in the absorbance revealed +3 the reducing power of extracts. The extract was found to inhibit Gram positive bacteria to more extent when compared to Gram negative bacteria. The minimum inhibitory concentration of extract was found to be less for Gram positive bacteria. A dose dependent mortality of second instar larvae of A. aegypti was observed in this study. The larval mortality was recorded as 100% in the case of 30mg/ml and higher concentrations of methanolic extract. Preliminary phytochemical analysis of methanol extract showed the presence of tannins, saponins, steroids and glycosides. The efficacy of extract of A. pulchellus may be attributed to the phytochemicals present in the solvent extract. Further studies on isolation of active constituents and their biological activities are to be carried out.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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Cited By Count: 35
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