Abstract: PET and SPECT are valuable clinical tools in the management of patients with medically resistant, partial epilepsy who are under evaluation for surgical treatment. The value of PET for localization of seizure activity has been fi rmly established for patients with temporal lobe epilepsy and extratemporal lobe epilepsy. It is a very useful test partly because it is non-invasive. The localizing value of ictal SPECT is based on cerebral metabolic and perfusion coupling. Ictal hyperperfusion is used to localize the epileptogenic zone noninvasively, and is particularly useful in MRI- negative partial epilepsy and focal cortical dysplasia. Use of subtraction ictal SPECT coregistered with MRI (SISCOM) improves localization area of hyperperfusion. However, ictal SPECT should be interpreted in the context of full presurgical evaluation
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
Access and Citation
Cited By Count: 1
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot