Title: Convenient removal of N-tert-butyl from amides with scandium triflate
Abstract: Scandium triflate has been used as a convenient and efficient catalyst for removal of N-tert-butyl from amide groups. A variety of N-tert-butyl aryl and alkyl amides under these conditions gave the corresponding primary amide in high yields. With the use of microwave heating the deprotection reaction could be completed within 1 h.
Publication Year: 2006
Publication Date: 2006-03-21
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 19
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