Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2181067591', 'doi': 'https://doi.org/10.1128/aac.01948-15', 'title': '<i>In Vitro</i> Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum', 'display_name': '<i>In Vitro</i> Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum', 'publication_year': 2015, 'publication_date': '2015-12-01', 'ids': {'openalex': 'https://openalex.org/W2181067591', 'doi': 'https://doi.org/10.1128/aac.01948-15', 'mag': '2181067591', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26416869', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4649191'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01948-15', 'pdf_url': 'https://aac.asm.org/content/aac/59/12/7650.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://aac.asm.org/content/aac/59/12/7650.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028226004', 'display_name': 'Mynthia Cabrera', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mynthia Cabrera', 'raw_affiliation_strings': ['Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5005484398', 'display_name': 'Liwang Cui', 'orcid': 'https://orcid.org/0000-0002-8338-1974'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Liwang Cui', 'raw_affiliation_strings': ['Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA', 'institution_ids': ['https://openalex.org/I130769515']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.836, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.943708, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '59', 'issue': '12', 'first_page': '7650', 'last_page': '7656'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10823', 'display_name': 'Global Burden of Leishmaniasis Incidence and Treatment', 'score': 0.9887, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10890', 'display_name': 'Epidemiology and Treatment of Chagas Disease', 'score': 0.9852, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/primaquine', 'display_name': 'Primaquine', 'score': 0.82071376}, {'id': 'https://openalex.org/keywords/lumefantrine', 'display_name': 'Lumefantrine', 'score': 0.76764256}, {'id': 'https://openalex.org/keywords/piperaquine', 'display_name': 'Piperaquine', 'score': 0.6765832}, {'id': 'https://openalex.org/keywords/artemether', 'display_name': 'Artemether', 'score': 0.51595527}, {'id': 'https://openalex.org/keywords/plasmodium-falciparum', 'display_name': 'Plasmodium falciparum', 'score': 0.503479}, {'id': 'https://openalex.org/keywords/dihydroartemisinin', 'display_name': 'Dihydroartemisinin', 'score': 0.41211212}], 'concepts': [{'id': 'https://openalex.org/C99389464', 'wikidata': 'https://www.wikidata.org/wiki/Q3319949', 'display_name': 'Gametocyte', 'level': 4, 'score': 0.9210024}, {'id': 'https://openalex.org/C2776793103', 'wikidata': 'https://www.wikidata.org/wiki/Q419834', 'display_name': 'Primaquine', 'level': 4, 'score': 0.82071376}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.81623495}, {'id': 'https://openalex.org/C2780780316', 'wikidata': 'https://www.wikidata.org/wiki/Q904464', 'display_name': 'Lumefantrine', 'level': 5, 'score': 0.76764256}, {'id': 'https://openalex.org/C2777199930', 'wikidata': 'https://www.wikidata.org/wiki/Q736270', 'display_name': 'Mefloquine', 'level': 4, 'score': 0.7503699}, {'id': 'https://openalex.org/C2777616469', 'wikidata': 'https://www.wikidata.org/wiki/Q7197338', 'display_name': 'Piperaquine', 'level': 5, 'score': 0.6765832}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.63704777}, {'id': 'https://openalex.org/C2777425658', 'wikidata': 'https://www.wikidata.org/wiki/Q422438', 'display_name': 'Chloroquine', 'level': 3, 'score': 0.63057226}, {'id': 'https://openalex.org/C2776120307', 'wikidata': 'https://www.wikidata.org/wiki/Q426921', 'display_name': 'Artemisinin', 'level': 4, 'score': 0.62485594}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.5792161}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.5471637}, {'id': 'https://openalex.org/C2778118209', 'wikidata': 'https://www.wikidata.org/wiki/Q416199', 'display_name': 'Artemether', 'level': 5, 'score': 0.51595527}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.4169253}, {'id': 'https://openalex.org/C2781160685', 'wikidata': 'https://www.wikidata.org/wiki/Q5276420', 'display_name': 'Dihydroartemisinin', 'level': 5, 'score': 0.41211212}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.35454285}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.17081064}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.08124918}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D011319', 'descriptor_name': 'Primaquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D034101', 'descriptor_name': 'Sporozoites', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D053058', 'descriptor_name': 'Trophozoites', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052160', 'descriptor_name': 'Benzothiazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003959', 'descriptor_name': 'Diamines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004338', 'descriptor_name': 'Drug Combinations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004347', 'descriptor_name': 'Drug Interactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004912', 'descriptor_name': 'Erythrocytes', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D004912', 'descriptor_name': 'Erythrocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004912', 'descriptor_name': 'Erythrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004983', 'descriptor_name': 'Ethanolamines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004983', 'descriptor_name': 'Ethanolamines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005449', 'descriptor_name': 'Fluorenes', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005449', 'descriptor_name': 'Fluorenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000078102', 'descriptor_name': 'Lumefantrine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009930', 'descriptor_name': 'Organic Chemicals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021261', 'descriptor_name': 'Parasitic Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011319', 'descriptor_name': 'Primaquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034101', 'descriptor_name': 'Sporozoites', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D034101', 'descriptor_name': 'Sporozoites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053058', 'descriptor_name': 'Trophozoites', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D053058', 'descriptor_name': 'Trophozoites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01948-15', 'pdf_url': 'https://aac.asm.org/content/aac/59/12/7650.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4649191', 'pdf_url': 'https://europepmc.org/articles/pmc4649191?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649191', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26416869', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01948-15', 'pdf_url': 'https://aac.asm.org/content/aac/59/12/7650.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.83, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 56, 'referenced_works': ['https://openalex.org/W1529291344', 'https://openalex.org/W1972177048', 'https://openalex.org/W1973828942', 'https://openalex.org/W1977560610', 'https://openalex.org/W1981089872', 'https://openalex.org/W2010940726', 'https://openalex.org/W2017080914', 'https://openalex.org/W2020251171', 'https://openalex.org/W2037912215', 'https://openalex.org/W2039859774', 'https://openalex.org/W2053732861', 'https://openalex.org/W2055971230', 'https://openalex.org/W2060739950', 'https://openalex.org/W2062627902', 'https://openalex.org/W2062863104', 'https://openalex.org/W2069521464', 'https://openalex.org/W2070778360', 'https://openalex.org/W2071249915', 'https://openalex.org/W2091684277', 'https://openalex.org/W2095918221', 'https://openalex.org/W2097263871', 'https://openalex.org/W2100119109', 'https://openalex.org/W2101792514', 'https://openalex.org/W2104386816', 'https://openalex.org/W2104536143', 'https://openalex.org/W2105812381', 'https://openalex.org/W2110269548', 'https://openalex.org/W2111179758', 'https://openalex.org/W2112191861', 'https://openalex.org/W2112261944', 'https://openalex.org/W2114818342', 'https://openalex.org/W2114971505', 'https://openalex.org/W2116952919', 'https://openalex.org/W2125306514', 'https://openalex.org/W2125851600', 'https://openalex.org/W2126821513', 'https://openalex.org/W2129999344', 'https://openalex.org/W2130475620', 'https://openalex.org/W2133949830', 'https://openalex.org/W2138754677', 'https://openalex.org/W2142999550', 'https://openalex.org/W2144894971', 'https://openalex.org/W2146883638', 'https://openalex.org/W2148420565', 'https://openalex.org/W2158323574', 'https://openalex.org/W2159526350', 'https://openalex.org/W2163816642', 'https://openalex.org/W2164191030', 'https://openalex.org/W2166670458', 'https://openalex.org/W2170675785', 'https://openalex.org/W2170680268', 'https://openalex.org/W2175472944', 'https://openalex.org/W2414942275', 'https://openalex.org/W2576097533', 'https://openalex.org/W2788073857', 'https://openalex.org/W62760635'], 'related_works': ['https://openalex.org/W4306160248', 'https://openalex.org/W3001610981', 'https://openalex.org/W2964860972', 'https://openalex.org/W2315590704', 'https://openalex.org/W2181067591', 'https://openalex.org/W2168759876', 'https://openalex.org/W2154497108', 'https://openalex.org/W2120453248', 'https://openalex.org/W2119652588', 'https://openalex.org/W2106202952'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Currently,': [1], 'the': [2, 36, 42, 46, 51, 65, 82, 87, 96, 113, 120, 146, 178, 181], 'World': [3], 'Health': [4], 'Organization': [5], 'recommends': [6], 'addition': [7], 'of': [8, 14, 39, 45, 57, 84, 98, 123], 'a': [9, 27, 74], '0.25-mg': [10], 'base/kg': [11], 'single': [12], 'dose': [13], 'primaquine': [15], '(PQ)': [16], 'to': [17, 107, 180], 'artemisinin': [18], 'combination': [19, 165], 'therapies': [20], '(ACTs)': [21], 'for': [22, 30, 49, 70, 78, 112, 145], 'Plasmodium': [23], 'falciparum': [24, 62, 125], 'malaria': [25], 'as': [26, 177], 'gametocytocidal': [28], 'agent': [29], 'reducing': [31], 'transmission.': [32], 'Here,': [33], 'we': [34, 80, 104], 'investigated': [35], 'potential': [37], 'interactions': [38, 83, 111, 157], 'PQ': [40, 85, 115, 159, 174], 'with': [41, 86, 139], 'long-lasting': [43], 'components': [44], 'ACT': [47, 183], 'drugs': [48], 'eliminating': [50], 'asexual': [52, 71, 132], 'blood': [53, 121], 'stages': [54, 122, 133], 'and': [55, 73, 93, 102, 116, 134, 149, 160], 'gametocytes': [56, 135], 'in': [58, 130], 'vitro': [59], '-cultured': [60], 'P.': [61, 124], 'strains.': [63, 127], 'Using': [64], 'SYBR': [66], 'green': [67], 'I': [68], 'assay': [69, 77], 'parasites': [72], 'flow': [75], 'cytometry-based': [76], 'gametocytes,': [79], 'determined': [81], 'schizonticides': [88], 'chloroquine,': [89], 'mefloquine,': [90], 'piperaquine,': [91], 'lumefantrine,': [92], 'naphthoquine.': [94], 'With': [95], 'sums': [97], 'fractional': [99], 'inhibitory': [100], 'concentrations': [101], 'isobolograms,': [103], 'were': [105], 'able': [106], 'determine': [108], 'mostly': [109], 'synergistic': [110], 'various': [114], 'schizonticide': [117], 'combinations': [118], 'on': [119], 'laboratory': [126], 'The': [128], 'synergism': [129, 142], 'inhibiting': [131], 'was': [136, 143], 'highly': [137], 'evident': [138], 'PQ-naphthoquine,': [140], 'whereas': [141], 'moderate': [144], 'PQ-piperaquine,': [147], 'PQ-chloroquine,': [148], 'PQ-mefloquine': [150], 'combinations.': [151], 'We': [152], 'have': [153], 'detected': [154], 'potentially': [155], 'antagonistic': [156], 'between': [158], 'lumefantrine': [161], 'under': [162], 'certain': [163], 'drug': [164], 'ratios,': [166], 'suggesting': [167], 'that': [168], 'precautions': [169], 'might': [170], 'be': [171], 'needed': [172], 'when': [173], 'is': [175], 'added': [176], 'gametocytocide': [179], 'artemether-lumefantrine': [182], '(Coartem).': [184]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2181067591', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}], 'updated_date': '2024-09-15T20:54:27.083033', 'created_date': '2016-06-24'}