Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2180875864', 'doi': 'https://doi.org/10.1242/dev.104.supplement.187', 'title': 'Expression of homeobox gene <i>Hox 1.1</i> during mouse embryogenesis', 'display_name': 'Expression of homeobox gene <i>Hox 1.1</i> during mouse embryogenesis', 'publication_year': 1988, 'publication_date': '1988-10-01', 'ids': {'openalex': 'https://openalex.org/W2180875864', 'doi': 'https://doi.org/10.1242/dev.104.supplement.187', 'mag': '2180875864', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2908296'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.104.supplement.187', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5066947665', 'display_name': 'Kathleen Mahon', 'orcid': 'https://orcid.org/0000-0002-8945-2235'}, 'institutions': [{'id': 'https://openalex.org/I4210144228', 'display_name': 'Eunice Kennedy Shriver National Institute of Child Health and Human Development', 'ror': 'https://ror.org/04byxyr05', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210144228']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kathleen A. Mahon', 'raw_affiliation_strings': ['National Institute of Child Health and Human Development, National Institutes of Health 1 Laboratory of Molecular Genetics , , Bethesda, Maryland 20892, USA'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Child Health and Human Development, National Institutes of Health 1 Laboratory of Molecular Genetics , , Bethesda, Maryland 20892, USA', 'institution_ids': ['https://openalex.org/I4210144228', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113633576', 'display_name': 'Heiner Westphal', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210144228', 'display_name': 'Eunice Kennedy Shriver National Institute of Child Health and Human Development', 'ror': 'https://ror.org/04byxyr05', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210144228']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Heiner Westphal', 'raw_affiliation_strings': ['National Institute of Child Health and Human Development, National Institutes of Health 1 Laboratory of Molecular Genetics , , Bethesda, Maryland 20892, USA'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Child Health and Human Development, National Institutes of Health 1 Laboratory of Molecular Genetics , , Bethesda, Maryland 20892, USA', 'institution_ids': ['https://openalex.org/I4210144228', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5035778542', 'display_name': 'Peter Gruß', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210131661', 'display_name': 'Max Planck Institute for Biophysical Chemistry', 'ror': 'https://ror.org/03e76ya46', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210131661']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Peter Gruss', 'raw_affiliation_strings': ['Max Planck Institute of Biophysical Chemistry 2 , Department of Molecular Cell Biology Am Fassberg, D-3400 Gottingen, FRG'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institute of Biophysical Chemistry 2 , Department of Molecular Cell Biology Am Fassberg, D-3400 Gottingen, FRG', 'institution_ids': ['https://openalex.org/I4210131661']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.679, 'has_fulltext': False, 'cited_by_count': 52, 'citation_normalized_percentile': {'value': 0.812067, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '104', 'issue': 'Supplement', 'first_page': '187', 'last_page': '195'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9566, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.9557, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/homeobox-a1', 'display_name': 'Homeobox A1', 'score': 0.8870977}, {'id': 'https://openalex.org/keywords/cdx2', 'display_name': 'CDX2', 'score': 0.74220407}, {'id': 'https://openalex.org/keywords/homeobox-protein-nkx-2.5', 'display_name': 'Homeobox protein Nkx-2.5', 'score': 0.7110292}, {'id': 'https://openalex.org/keywords/emx2', 'display_name': 'EMX2', 'score': 0.5750775}, {'id': 'https://openalex.org/keywords/hnf1b', 'display_name': 'HNF1B', 'score': 0.5587787}, {'id': 'https://openalex.org/keywords/dlx5', 'display_name': 'DLX5', 'score': 0.51919425}], 'concepts': [{'id': 'https://openalex.org/C121587040', 'wikidata': 'https://www.wikidata.org/wiki/Q898769', 'display_name': 'Homeobox', 'level': 4, 'score': 0.978898}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.92566615}, {'id': 'https://openalex.org/C111039654', 'wikidata': 'https://www.wikidata.org/wiki/Q253149', 'display_name': 'Hox gene', 'level': 4, 'score': 0.908643}, {'id': 'https://openalex.org/C103652617', 'wikidata': 'https://www.wikidata.org/wiki/Q18027119', 'display_name': 'Homeobox A1', 'level': 5, 'score': 0.8870977}, {'id': 'https://openalex.org/C131364181', 'wikidata': 'https://www.wikidata.org/wiki/Q17860880', 'display_name': 'CDX2', 'level': 5, 'score': 0.74220407}, {'id': 'https://openalex.org/C180504324', 'wikidata': 'https://www.wikidata.org/wiki/Q17911158', 'display_name': 'Homeobox protein Nkx-2.5', 'level': 5, 'score': 0.7110292}, {'id': 'https://openalex.org/C46751350', 'wikidata': 'https://www.wikidata.org/wiki/Q1939530', 'display_name': 'Homeotic gene', 'level': 4, 'score': 0.6605178}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.59546816}, {'id': 'https://openalex.org/C61342607', 'wikidata': 'https://www.wikidata.org/wiki/Q17916811', 'display_name': 'EMX2', 'level': 5, 'score': 0.5750775}, {'id': 'https://openalex.org/C136013683', 'wikidata': 'https://www.wikidata.org/wiki/Q21119107', 'display_name': 'HNF1B', 'level': 5, 'score': 0.5587787}, {'id': 'https://openalex.org/C117072055', 'wikidata': 'https://www.wikidata.org/wiki/Q21102620', 'display_name': 'DLX5', 'level': 5, 'score': 0.51919425}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.48051322}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.47296208}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.47045434}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.36410847}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.33881444}], 'mesh': [{'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005801', 'descriptor_name': 'Genes, Homeobox', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004627', 'descriptor_name': 'Embryonic Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009024', 'descriptor_name': 'Morphogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.104.supplement.187', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2908296', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life on land', 'score': 0.63, 'id': 'https://metadata.un.org/sdg/15'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W1511324718', 'https://openalex.org/W1815472980', 'https://openalex.org/W1882773106', 'https://openalex.org/W1972693622', 'https://openalex.org/W1972858120', 'https://openalex.org/W1975538460', 'https://openalex.org/W1977792329', 'https://openalex.org/W1981525963', 'https://openalex.org/W1987038120', 'https://openalex.org/W1995112067', 'https://openalex.org/W2007813753', 'https://openalex.org/W2008657400', 'https://openalex.org/W2011784487', 'https://openalex.org/W2012626852', 'https://openalex.org/W2014885676', 'https://openalex.org/W2022893667', 'https://openalex.org/W2023660511', 'https://openalex.org/W2027249250', 'https://openalex.org/W2036181829', 'https://openalex.org/W2041519679', 'https://openalex.org/W2043466269', 'https://openalex.org/W2049785220', 'https://openalex.org/W2050688803', 'https://openalex.org/W2053352747', 'https://openalex.org/W2055310816', 'https://openalex.org/W2058016005', 'https://openalex.org/W2073212437', 'https://openalex.org/W2084808610', 'https://openalex.org/W2085171463', 'https://openalex.org/W2086495794', 'https://openalex.org/W2105207670', 'https://openalex.org/W2114963163', 'https://openalex.org/W2120591530', 'https://openalex.org/W2124943691', 'https://openalex.org/W2125082575', 'https://openalex.org/W2169340257', 'https://openalex.org/W2183139415', 'https://openalex.org/W2207269118', 'https://openalex.org/W2215219126', 'https://openalex.org/W2299794562', 'https://openalex.org/W2405685946', 'https://openalex.org/W313484932', 'https://openalex.org/W4210661528', 'https://openalex.org/W4229670018', 'https://openalex.org/W81484962', 'https://openalex.org/W916102965'], 'related_works': ['https://openalex.org/W2464014185', 'https://openalex.org/W2410574238', 'https://openalex.org/W2390334166', 'https://openalex.org/W2378404761', 'https://openalex.org/W2167886576', 'https://openalex.org/W2086749638', 'https://openalex.org/W2034428134', 'https://openalex.org/W2022758068', 'https://openalex.org/W2001163744', 'https://openalex.org/W1970374717'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Many': [1], 'of': [2, 30, 78, 93, 95, 137, 145, 147, 160, 210, 216], 'the': [3, 20, 34, 57, 76, 88, 104, 133, 138, 161, 208, 214, 217], 'genes': [4, 45, 67, 98, 153, 189], 'controlling': [5], 'segmentation': [6, 198], 'and': [7, 37, 74, 90, 135, 150, 169], 'pattern': [8], 'formation': [9, 134], 'in': [10, 27, 51, 112, 128, 156, 177, 197, 199, 207], 'Drosophila': [11], 'contain': [12], 'a': [13, 28, 48, 129, 205], 'conserved': [14], '183': [15], 'bp': [16], 'sequence': [17], 'known': [18], 'as': [19, 108], 'homeobox.': [21], 'Homeobox': [22], 'sequences': [23], 'have': [24], 'been': [25, 121], 'found': [26, 122], 'range': [29], 'metazoan': [31], 'species,': [32], 'including': [33], 'vertebrates': [35], 'mouse': [36], 'man.': [38], 'This': [39], 'striking': [40, 143], 'conservation': [41], 'suggests': [42], 'that': [43, 64, 75, 123, 187], 'homeobox': [44, 66, 97, 152, 188], 'may': [46], 'play': [47, 193], 'fundamental': [49], 'role': [50, 196, 206], 'developmental': [52], 'processes.': [53], 'If': [54], 'this': [55], 'is': [56, 126, 174], 'case': [58], 'then': [59], 'it': [60, 119], 'might': [61], 'be': [62, 69, 100], 'expected': [63], 'vertebrate': [65], 'will': [68, 81, 99], 'differentially': [70], 'expressed': [71, 127], 'during': [72, 132], 'embryogenesis': [73], 'timing': [77], 'their': [79], 'expression': [80, 94, 146, 173], 'coincide': [82], 'with': [83, 179, 204], 'major': [84], 'morphogenetic': [85], 'events.': [86], 'Here': [87], 'spatial': [89], 'temporal': [91], 'patterns': [92, 144], 'murine': [96], 'explored,': [101], 'concentrating': [102], 'on': [103], 'Hox': [105, 124, 148], '1.1': [106, 125, 149], 'gene': [107], 'an': [109, 194], 'example.': [110], 'Using': [111], 'situ': [113], 'hybridization': [114], 'to': [115], 'localize': [116], 'RNA': [117], 'transcripts,': [118], 'has': [120], 'region-specific': [130], 'manner': [131], 'differentiation': [136], 'embryonic': [139], 'anteroposterior': [140], 'axis.': [141], 'Although': [142], 'other': [151], 'are': [154, 202], 'seen': [155, 176], 'overtly': [157], 'segmented': [158], 'structures': [159], 'embryo': [162], '(i.e.': [163], 'somites,': [164], 'prevertebral': [165], 'elements,': [166], 'neural': [167], 'tube': [168], 'dorsal': [170], 'spinal': [171], 'ganglia)': [172], 'also': [175], 'tissues': [178], 'no': [180], 'obvious': [181], 'segmental': [182], 'origin.': [183], 'The': [184], 'results': [185], 'suggest': [186], 'probably': [190], 'do': [191], 'not': [192], 'exclusive': [195], 'vertebrates,': [200], 'but': [201], 'consistent': [203], 'assignment': [209], 'positional': [211], 'identity': [212], 'along': [213], 'axis': [215], 'embryo.': [218]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2180875864', 'counts_by_year': [{'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-09T23:07:55.938060', 'created_date': '2016-06-24'}