Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2179886742', 'doi': 'https://doi.org/10.18632/oncotarget.5072', 'title': 'TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition', 'display_name': 'TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition', 'publication_year': 2015, 'publication_date': '2015-08-21', 'ids': {'openalex': 'https://openalex.org/W2179886742', 'doi': 'https://doi.org/10.18632/oncotarget.5072', 'mag': '2179886742', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26334958', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4745711'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5072', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5072&path%5B%5D=12083', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5072&path%5B%5D=12083', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5032770424', 'display_name': 'Samil Jung', 'orcid': 'https://orcid.org/0000-0003-1299-9424'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Samil Jung', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071946137', 'display_name': 'Chengping Li', 'orcid': 'https://orcid.org/0000-0001-5280-8384'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Chengping Li', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067865085', 'display_name': 'Jingjing Duan', 'orcid': 'https://orcid.org/0000-0002-4008-2536'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jingjing Duan', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031660872', 'display_name': 'Soonduck Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Soonduck Lee', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047027503', 'display_name': 'Kyeri Kim', 'orcid': 'https://orcid.org/0000-0003-1503-9090'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Kyeri Kim', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005189995', 'display_name': 'Yeonji Park', 'orcid': 'https://orcid.org/0000-0002-6909-6675'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yeonji Park', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051164633', 'display_name': 'Young Yang', 'orcid': 'https://orcid.org/0000-0003-4239-0804'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Young Yang', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053258609', 'display_name': 'Keun-Il Kim', 'orcid': 'https://orcid.org/0000-0002-7899-3861'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Keun-Il Kim', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077530265', 'display_name': 'Jong‐Seok Lim', 'orcid': 'https://orcid.org/0000-0003-4024-6868'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jong-Seok Lim', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027296001', 'display_name': 'Chung-Il Cheon', 'orcid': 'https://orcid.org/0009-0009-9317-6200'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Chung-Il Cheon', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062364308', 'display_name': 'Young‐Sook Kang', 'orcid': 'https://orcid.org/0000-0002-8573-4657'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Young-Sook Kang', 'raw_affiliation_strings': ["College of Pharmacy, Sookmyung Women's University, Seoul, 140-742, South Korea", "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "College of Pharmacy, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}, {'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077426788', 'display_name': 'Myeong‐Sok Lee', 'orcid': 'https://orcid.org/0000-0002-2434-0048'}, 'institutions': [{'id': 'https://openalex.org/I31766871', 'display_name': "Sookmyung Women's University", 'ror': 'https://ror.org/00vvvt117', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I31766871']}], 'countries': ['KR'], 'is_corresponding': True, 'raw_author_name': 'Myeong-Sok Lee', 'raw_affiliation_strings': ["Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea"], 'affiliations': [{'raw_affiliation_string': "Department of Life Systems, Sookmyung Women's University, Seoul, 140-742, South Korea", 'institution_ids': ['https://openalex.org/I31766871']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5077426788'], 'corresponding_institution_ids': ['https://openalex.org/I31766871'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.441, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.780137, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '6', 'issue': '30', 'first_page': '29060', 'last_page': '29075'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10587', 'display_name': 'Role of Autophagy in Disease and Health', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/xiap', 'display_name': 'XIAP', 'score': 0.79819787}, {'id': 'https://openalex.org/keywords/tumor-suppression', 'display_name': 'Tumor Suppression', 'score': 0.549667}, {'id': 'https://openalex.org/keywords/cancer-therapy', 'display_name': 'Cancer Therapy', 'score': 0.536094}, {'id': 'https://openalex.org/keywords/inhibitor-of-apoptosis', 'display_name': 'Inhibitor of apoptosis', 'score': 0.45860443}], 'concepts': [{'id': 'https://openalex.org/C203522944', 'wikidata': 'https://www.wikidata.org/wiki/Q288322', 'display_name': 'Autophagy', 'level': 3, 'score': 0.8447865}, {'id': 'https://openalex.org/C94030615', 'wikidata': 'https://www.wikidata.org/wiki/Q3346925', 'display_name': 'Necroptosis', 'level': 4, 'score': 0.8438448}, {'id': 'https://openalex.org/C33195913', 'wikidata': 'https://www.wikidata.org/wiki/Q20970121', 'display_name': 'XIAP', 'level': 5, 'score': 0.79819787}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.7717296}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.53635746}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.50874835}, {'id': 'https://openalex.org/C2777408456', 'wikidata': 'https://www.wikidata.org/wiki/Q174299', 'display_name': 'Inhibitor of apoptosis', 'level': 4, 'score': 0.45860443}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.44864684}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33714557}, {'id': 'https://openalex.org/C98424977', 'wikidata': 'https://www.wikidata.org/wiki/Q25805', 'display_name': 'Caspase', 'level': 4, 'score': 0.27719146}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.2696848}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.12961099}], 'mesh': [{'descriptor_ui': 'D000596', 'descriptor_name': 'Amino Acids', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001343', 'descriptor_name': 'Autophagy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000596', 'descriptor_name': 'Amino Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016895', 'descriptor_name': 'Culture Media, Serum-Free', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016895', 'descriptor_name': 'Culture Media, Serum-Free', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061986', 'descriptor_name': 'MCF-7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D041681', 'descriptor_name': 'NIH 3T3 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009336', 'descriptor_name': 'Necrosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D058539', 'descriptor_name': 'Phosphatidylinositol 3-Kinase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058539', 'descriptor_name': 'Phosphatidylinositol 3-Kinase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051057', 'descriptor_name': 'Proto-Oncogene Proteins c-akt', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051057', 'descriptor_name': 'Proto-Oncogene Proteins c-akt', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051636', 'descriptor_name': 'X-Linked Inhibitor of Apoptosis Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051636', 'descriptor_name': 'X-Linked Inhibitor of Apoptosis Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5072', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5072&path%5B%5D=12083', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4745711', 'pdf_url': 'https://europepmc.org/articles/pmc4745711?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745711', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26334958', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5072', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=5072&path%5B%5D=12083', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.69}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 56, 'referenced_works': ['https://openalex.org/W1528462551', 'https://openalex.org/W1557686543', 'https://openalex.org/W1607777232', 'https://openalex.org/W1659912652', 'https://openalex.org/W1930222102', 'https://openalex.org/W1968023901', 'https://openalex.org/W1973628719', 'https://openalex.org/W1979859269', 'https://openalex.org/W1988681423', 'https://openalex.org/W1992401642', 'https://openalex.org/W1997238548', 'https://openalex.org/W1998152698', 'https://openalex.org/W2007448026', 'https://openalex.org/W2009891171', 'https://openalex.org/W2010559308', 'https://openalex.org/W2011014580', 'https://openalex.org/W2011342890', 'https://openalex.org/W2020488814', 'https://openalex.org/W2026958018', 'https://openalex.org/W2027810683', 'https://openalex.org/W2029962300', 'https://openalex.org/W2031949901', 'https://openalex.org/W2034279252', 'https://openalex.org/W2037064466', 'https://openalex.org/W2043724674', 'https://openalex.org/W2044446578', 'https://openalex.org/W2046025619', 'https://openalex.org/W2061260890', 'https://openalex.org/W2061497413', 'https://openalex.org/W2062917145', 'https://openalex.org/W2071650421', 'https://openalex.org/W2096592022', 'https://openalex.org/W2100783563', 'https://openalex.org/W2107480391', 'https://openalex.org/W2108086395', 'https://openalex.org/W2109890960', 'https://openalex.org/W2109913113', 'https://openalex.org/W2115788076', 'https://openalex.org/W2117004196', 'https://openalex.org/W2120492514', 'https://openalex.org/W2131007152', 'https://openalex.org/W2137685612', 'https://openalex.org/W2139410513', 'https://openalex.org/W2139573571', 'https://openalex.org/W2141846416', 'https://openalex.org/W2145006562', 'https://openalex.org/W2145446700', 'https://openalex.org/W2155836292', 'https://openalex.org/W2156320420', 'https://openalex.org/W2157638939', 'https://openalex.org/W2166273613', 'https://openalex.org/W2170839629', 'https://openalex.org/W2171128507', 'https://openalex.org/W2172249877', 'https://openalex.org/W2335360255', 'https://openalex.org/W4237625145'], 'related_works': ['https://openalex.org/W4235501119', 'https://openalex.org/W3032774863', 'https://openalex.org/W3007935161', 'https://openalex.org/W2945460431', 'https://openalex.org/W2885499773', 'https://openalex.org/W2613766095', 'https://openalex.org/W2393927319', 'https://openalex.org/W2376246323', 'https://openalex.org/W2315480619', 'https://openalex.org/W1967986851'], 'abstract_inverted_index': {'//': [0], 'Samil': [1], 'Jung': [2], '1,': [3, 8], '*': [4, 9, 73], ',': [5, 10, 14, 18, 22, 26, 30, 34, 38, 42, 46], 'Chengping': [6], 'Li': [7], 'Jingjing': [11], 'Duan': [12], '1': [13, 17, 21, 25, 29, 33, 37, 41, 49, 50], 'Soonduck': [15], 'Lee': [16, 48], 'Kyeri': [19], 'Kim': [20, 32], 'Yeonji': [23], 'Park': [24], 'Young': [27], 'Yang': [28], 'Keun-Il': [31], 'Jong-Seok': [35], 'Lim': [36], 'Chung-Il': [39], 'Cheon': [40], 'Young-Sook': [43], 'Kang': [44], '2': [45, 62], 'Myeong-Sok': [47, 84], 'Department': [51], 'of': [52, 64, 111, 161, 186, 209, 223, 261, 308, 323], 'Life': [53], 'Systems,': [54], 'Sookmyung': [55, 66], "Women's": [56, 67], 'University,': [57, 68], 'Seoul,': [58, 69], '140-742,': [59, 70], 'South': [60, 71], 'Korea': [61, 72], 'College': [63], 'Pharmacy,': [65], 'These': [74], 'authors': [75], 'have': [76, 138], 'contributed': [77], 'equally': [78], 'to': [79, 137, 168, 284, 316], 'this': [80, 145, 279], 'work': [81], 'Correspondence': [82], 'to:': [83], 'Lee,': [85], 'e-mail:': [86], '[email protected]': [87], 'Keywords:': [88], 'TRIP-Br1,': [89, 96], 'autophagy,': [90, 157], 'apoptosis,': [91, 158], 'necroptosis,': [92], 'nutrient/serum': [93, 172], 'starvation': [94, 218, 314], 'Abbreviations:': [95], 'Transcriptional': [97], 'regulator': [98], 'interacting': [99], 'with': [100, 183, 201, 255], 'the': [101, 171, 221, 244, 256, 259, 291, 305, 321], 'PHD-bromodomain': [102], '1;': [103], 'ROS,': [104], 'Reactive': [105], 'Oxygen': [106], 'Species;': [107], 'XIAP,': [108], 'X-linked': [109], 'inhibitor': [110], 'apoptosis': [112, 275], 'protein;': [113], 'PCD,': [114], 'Programed': [115], 'cell': [116, 203, 231, 247, 271, 287], 'death': [117, 272], 'Received:': [118], 'May': [119], '28,': [120], '2015': [121, 125, 129], 'Accepted:': [122], 'August': [123, 127], '10,': [124], 'Published:': [126], '21,': [128], 'ABSTRACT': [130], 'TRIP-Br1': [131, 150, 175, 224, 262, 281, 309], 'oncogenic': [132], 'protein': [133, 293, 310], 'has': [134], 'been': [135], 'shown': [136], 'multiple': [139], 'biological': [140], 'functions': [141, 151], 'in': [142, 181, 206, 226, 243, 318], 'cells.': [143], 'In': [144, 278], 'study,': [146], 'we': [147], 'demonstrate': [148], 'that': [149, 304], 'as': [152], 'an': [153], 'oncoprotein': [154], 'by': [155, 193, 273, 289], 'inhibiting': [156, 295], 'and': [159, 164, 239, 251, 267, 276, 294], 'necroptosis': [160], 'cancer': [162, 195, 230], 'cells': [163, 196, 269], 'eventually': [165], 'helping': [166], 'them': [167], 'survive': [169], 'under': [170], 'starved': [173], 'condition.': [174], 'expression': [176, 222], 'level': [177], 'was': [178], 'significantly': [179, 219], 'increased': [180], 'conditions': [182, 190], 'low': [184], 'levels': [185], 'nutrients.': [187], 'Nutrient': [188], 'depleted': [189], 'were': [191, 199], 'induced': [192], 'culturing': [194], 'until': [197], 'they': [198], 'overcrowded': [200], 'high': [202], 'density': [204], 'or': [205, 213], 'media': [207], 'deprived': [208], 'glucose,': [210], 'amino': [211], 'acids,': [212], 'serum.': [214], 'Among': [215], 'them,': [216], 'serum': [217, 285, 313], 'enhanced': [220], 'only': [225], 'all': [227], 'tested': [228], 'breast': [229], 'lines': [232, 248], '(MCF7,': [233], 'MDA-MB-231,': [234], 'T47D,': [235], 'MDA-MB-435,': [236], 'Hs578D,': [237], 'BT549,': [238], 'MDA-MB-435)': [240], 'but': [241], 'not': [242], 'three': [245], 'normal': [246], '(MCF10A,': [249], 'HfCH8,': [250], 'NIH3T3).': [252], 'As': [253], 'compared': [254], 'control': [257], 'cells,': [258], 'introduction': [260], 'silencing': [263], 'siRNA': [264], 'into': [265], 'MCF7': [266], 'MDA-MB-231': [268], 'accelerated': [270], 'inducing': [274], 'necroptosis.': [277], 'process,': [280], 'confers': [282], 'resistance': [283], 'starvation-induced': [286], 'deaths': [288], 'stabilizing': [290], 'XIAP': [292], 'cellular': [296], 'ROS': [297], 'production.': [298], 'Moreover,': [299], 'our': [300], 'data': [301], 'also': [302], 'show': [303], 'intracellular': [306], 'increase': [307], 'resulting': [311], 'from': [312], 'seems': [315], 'occur': [317], 'part': [319], 'through': [320], 'blockage': [322], 'PI3K/AKT': [324], 'signaling': [325], 'pathway.': [326]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2179886742', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}], 'updated_date': '2024-09-18T23:23:21.070385', 'created_date': '2016-06-24'}