Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2178105926', 'doi': 'https://doi.org/10.18632/oncotarget.5801', 'title': 'The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore', 'display_name': 'The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore', 'publication_year': 2015, 'publication_date': '2015-09-22', 'ids': {'openalex': 'https://openalex.org/W2178105926', 'doi': 'https://doi.org/10.18632/oncotarget.5801', 'mag': '2178105926', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26415232', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4742128'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5801', 'pdf_url': 'https://www.oncotarget.com/article/5801/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/5801/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087074811', 'display_name': 'Cheng Sun', 'orcid': 'https://orcid.org/0000-0002-8799-7426'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Cheng Sun', 'raw_affiliation_strings': ['Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I76130692', 'https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100693093', 'display_name': 'Jing Xu', 'orcid': 'https://orcid.org/0000-0002-4713-2807'}, 'institutions': [{'id': 'https://openalex.org/I4391768007', 'display_name': 'State Key Laboratory of Oncology in South China', 'ror': 'https://ror.org/04dn2ax39', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I157773358', 'https://openalex.org/I4391768007']}, {'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jing Xu', 'raw_affiliation_strings': ['Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4391768007', 'https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101507716', 'display_name': 'Jiaxi Song', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiaxi Song', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056811922', 'display_name': 'Chaoqun Liu', 'orcid': 'https://orcid.org/0000-0002-2691-7947'}, 'institutions': [{'id': 'https://openalex.org/I4391768007', 'display_name': 'State Key Laboratory of Oncology in South China', 'ror': 'https://ror.org/04dn2ax39', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I157773358', 'https://openalex.org/I4391768007']}, {'id': 'https://openalex.org/I4210146711', 'display_name': 'Sun Yat-sen University Cancer Center', 'ror': 'https://ror.org/0400g8r85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146711']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'ChaoQun Liu', 'raw_affiliation_strings': ['Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China', 'institution_ids': ['https://openalex.org/I4391768007', 'https://openalex.org/I4210146711', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100614566', 'display_name': 'Jinyu Wang', 'orcid': 'https://orcid.org/0000-0001-5689-6174'}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jinyu Wang', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055718370', 'display_name': 'Chenchun Weng', 'orcid': 'https://orcid.org/0000-0002-5440-3783'}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chenchun Weng', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101674975', 'display_name': 'Haoyu Sun', 'orcid': 'https://orcid.org/0000-0002-7506-8806'}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Haoyu Sun', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012198733', 'display_name': 'Haiming Wei', 'orcid': 'https://orcid.org/0000-0002-1675-6502'}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Haiming Wei', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027364189', 'display_name': 'Weihua Xiao', 'orcid': 'https://orcid.org/0000-0001-9102-6326'}, 'institutions': [{'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Weihua Xiao', 'raw_affiliation_strings': ['Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I126520041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041353057', 'display_name': 'Rui Sun', 'orcid': 'https://orcid.org/0000-0001-5259-9391'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rui Sun', 'raw_affiliation_strings': ['Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I76130692', 'https://openalex.org/I126520041']}, {'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5083130438', 'display_name': 'Zhigang Tian', 'orcid': 'https://orcid.org/0000-0002-5512-6378'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I126520041', 'display_name': 'University of Science and Technology of China', 'ror': 'https://ror.org/04c4dkn09', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I126520041', 'https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhigang Tian', 'raw_affiliation_strings': ['Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China'], 'affiliations': [{'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science & Technology of China, Hefei, Anhui, China', 'institution_ids': ['https://openalex.org/I76130692', 'https://openalex.org/I126520041']}, {'raw_affiliation_string': 'Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China', 'institution_ids': ['https://openalex.org/I76130692']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.565, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 67, 'citation_normalized_percentile': {'value': 0.89255, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '6', 'issue': '34', 'first_page': '35602', 'last_page': '35615'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.8231088}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8047136}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.6295718}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6104117}, {'id': 'https://openalex.org/C50382708', 'wikidata': 'https://www.wikidata.org/wiki/Q223218', 'display_name': 'Proportional hazards model', 'level': 2, 'score': 0.6058448}, {'id': 'https://openalex.org/C38180746', 'wikidata': 'https://www.wikidata.org/wiki/Q1952580', 'display_name': 'Multivariate analysis', 'level': 2, 'score': 0.5852933}, {'id': 'https://openalex.org/C3019719930', 'wikidata': 'https://www.wikidata.org/wiki/Q3910099', 'display_name': 'Predictive value', 'level': 2, 'score': 0.55474705}, {'id': 'https://openalex.org/C3019894029', 'wikidata': 'https://www.wikidata.org/wiki/Q332823', 'display_name': 'Overall survival', 'level': 2, 'score': 0.47559604}, {'id': 'https://openalex.org/C10515644', 'wikidata': 'https://www.wikidata.org/wiki/Q543310', 'display_name': 'Survival analysis', 'level': 2, 'score': 0.46033487}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.44731033}, {'id': 'https://openalex.org/C161584116', 'wikidata': 'https://www.wikidata.org/wiki/Q1952580', 'display_name': 'Multivariate statistics', 'level': 2, 'score': 0.43477696}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.4130105}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3288352}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.20912924}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.18495217}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D016246', 'descriptor_name': 'Lymphocytes, Tumor-Infiltrating', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007159', 'descriptor_name': 'Immunologic Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D007159', 'descriptor_name': 'Immunologic Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016246', 'descriptor_name': 'Lymphocytes, Tumor-Infiltrating', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5801', 'pdf_url': 'https://www.oncotarget.com/article/5801/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4742128', 'pdf_url': 'https://europepmc.org/articles/pmc4742128?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742128', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26415232', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.5801', 'pdf_url': 'https://www.oncotarget.com/article/5801/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.5, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1537822576', 'https://openalex.org/W1754851442', 'https://openalex.org/W1859257957', 'https://openalex.org/W1967954493', 'https://openalex.org/W1978993716', 'https://openalex.org/W1982062359', 'https://openalex.org/W2030713950', 'https://openalex.org/W2049029511', 'https://openalex.org/W2069087118', 'https://openalex.org/W2069169522', 'https://openalex.org/W2070583523', 'https://openalex.org/W2076910098', 'https://openalex.org/W2089220120', 'https://openalex.org/W2093773243', 'https://openalex.org/W2094006009', 'https://openalex.org/W2095598060', 'https://openalex.org/W2095864883', 'https://openalex.org/W2096151993', 'https://openalex.org/W2096910745', 'https://openalex.org/W2101585919', 'https://openalex.org/W2105459360', 'https://openalex.org/W2107766941', 'https://openalex.org/W2109159921', 'https://openalex.org/W2119301589', 'https://openalex.org/W2120338564', 'https://openalex.org/W2122656254', 'https://openalex.org/W2136313650', 'https://openalex.org/W2142300779', 'https://openalex.org/W2148605435', 'https://openalex.org/W2154697747', 'https://openalex.org/W2164355106', 'https://openalex.org/W2196944733', 'https://openalex.org/W2560367415'], 'related_works': ['https://openalex.org/W837686567', 'https://openalex.org/W4362347072', 'https://openalex.org/W3193998276', 'https://openalex.org/W3135804592', 'https://openalex.org/W3110381201', 'https://openalex.org/W2948807893', 'https://openalex.org/W2362802330', 'https://openalex.org/W2102964659', 'https://openalex.org/W2068236691', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'//': [0, 129, 133], 'Cheng': [1, 126], 'Sun': [2, 26, 38, 109], '1,2': [3, 39, 43], ',': [4, 8, 12, 16, 20, 24, 28, 32, 36, 283, 286, 289, 335], 'Jing': [5], 'Xu': [6], '3': [7, 15, 108], 'Jiaxi': [9], 'Song': [10], '1': [11, 19, 23, 27, 31, 35, 44], 'ChaoQun': [13], 'Liu': [14], 'Jinyu': [17], 'Wang': [18], 'Chenchun': [21], 'Weng': [22], 'Haoyu': [25], 'Haiming': [29], 'Wei': [30], 'Weihua': [33], 'Xiao': [34], 'Rui': [37], 'and': [40, 48, 56, 63, 82, 92, 174, 181, 187, 226, 244, 292, 308, 348], 'Zhigang': [41, 130], 'Tian': [42], 'Institute': [45], 'of': [46, 53, 60, 67, 71, 84, 94, 101, 117, 171, 184, 202, 247, 259, 368, 373], 'Immunology': [47], 'The': [49, 161], 'CAS': [50], 'Key': [51, 88, 115], 'Laboratory': [52, 89, 116], 'Innate': [54], 'Immunity': [55], 'Chronic': [57], 'Disease,': [58], 'School': [59], 'Life': [61], 'Sciences': [62], 'Medical': [64], 'Center,': [65, 113], 'University': [66, 111], 'Science': [68], '&': [69], 'Technology': [70], 'China,': [72, 121], 'Hefei,': [73], 'Anhui,': [74], 'China': [75, 107, 123], '2': [76, 334], 'Collaborative': [77], 'Innovation': [78], 'Center': [79], 'for': [80, 90], 'Diagnosis': [81, 91], 'Treatment': [83, 93], 'Infectious': [85, 95], 'Diseases,': [86, 96], 'State': [87, 114], 'First': [97], 'Affiliated': [98], 'Hospital,': [99], 'College': [100], 'Medicine,': [102], 'Zhejiang': [103], 'University,': [104], 'Hangzhou,': [105], 'Zhejiang,': [106], 'Yat-Sen': [110], 'Cancer': [112], 'Oncology': [118], 'in': [119, 178, 199, 206, 310, 353, 376], 'South': [120], 'Guangzhou,': [122], 'Correspondence': [124], 'to:': [125], 'Sun,': [127], 'email:': [128, 132], 'Tian,': [131], 'Keywords': [134], ':': [135, 146, 151, 156], 'CD8': [136, 172, 275, 281, 284, 294, 329, 344, 349, 360], '+': [137, 173, 176], 'T': [138], 'cells,': [139], 'Immunoscore,': [140], 'HCC,': [141], 'prognostic': [142, 269, 303], 'indicator,': [143, 299], 'TNM': [144], 'Received': [145], 'June': [147], '30,': [148], '2015': [149, 154, 159], 'Accepted': [150], 'September': [152, 157], '12,': [153], 'Published': [155], '22,': [158], 'Abstract': [160], 'increasing': [162], 'evidences': [163], 'suggest': [164, 358], 'that': [165, 359], 'Immunoscore(IS),': [166], 'a': [167, 200, 236, 240], 'combinatorial': [168], 'density': [169], 'analysis': [170, 315, 363], 'CD3': [175, 287, 290], 'cells': [177, 331], 'the': [179, 193, 251, 257, 267, 274, 301, 323, 341, 366], 'centre': [180], 'invasive': [182], 'margin': [183], 'tumour': [185, 196, 230], '(CT': [186], 'IM),': [188], 'has': [189], 'an': [190, 297], 'advantage': [191], 'over': [192], 'currently': [194], 'used': [195, 338], 'staging': [197, 231], 'methods': [198], 'variety': [201], 'tumours;': [203], 'however,': [204, 261], 'IS': [205, 214, 242, 252, 262], 'hepatocellular': [207], 'carcinoma': [208], 'remains': [209], 'unreported.': [210], 'In': [211, 320], 'this': [212], 'study,': [213, 322], 'was': [215, 253, 327], 'performed': [216], 'on': [217, 305], 'serial': [218], 'sections': [219], 'from': [220], 'two': [221], 'HCC': [222, 248], 'cohorts': [223], '(total': [224], '449)': [225], 'compared': [227, 272], 'with': [228, 273, 371], 'current': [229], 'systems.': [232], 'Kaplan–Meier': [233], 'curves': [234], 'illustrate': [235], 'positive': [237], 'association': [238], 'between': [239], 'higher': [241], '(IS≥2)': [243], 'longer': [245], 'survival': [246, 369], 'patients.': [249], 'Although': [250], 'highly': [254], 'related': [255], 'to': [256, 265, 336, 339], 'outcome': [258], 'patients,': [260], 'seems': [263], 'not': [264], 'be': [266, 337], 'optimal': [268], 'factor': [270], 'when': [271], 'CT': [276, 282, 288, 330, 345, 350, 361], '.': [277], 'As': [278], 'noted,': [279], 'among': [280], 'IM': [285, 291], 'IS,': [293], 'CT,': [295], 'as': [296], 'independent': [298], 'demonstrated': [300], 'highest': [302], 'impact': [304], 'both': [306], 'DFS': [307], 'OS': [309], 'our': [311, 321], 'Cox': [312], 'multivariate': [313], 'regression': [314], '(': [316], 'P': [317], '<': [318], '0.0001).': [319], 'minimum': [324], 'cut-off': [325], 'value': [326], '93': [328], 'per': [332], 'mm': [333], 'divide': [340], 'patients': [342], 'into': [343], 'Hi': [346], 'group': [347, 352], 'Lo': [351], 'clinical': [354, 374], 'settings.': [355], 'Our': [356], 'results': [357], 'densities': [362], 'notably': [364], 'improved': [365], 'accuracy': [367], 'prediction': [370], 'convenience': [372], 'manipulation': [375], 'HCC.': [377]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2178105926', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 4}], 'updated_date': '2024-12-24T13:17:57.451284', 'created_date': '2016-06-24'}