Publication Information

{'id': 'https://openalex.org/W2171509350', 'doi': 'https://doi.org/10.1093/infdis/172.4.1042', 'title': 'Successful Prevention and Treatment of Babesiosis with Atovaquone', 'display_name': 'Successful Prevention and Treatment of Babesiosis with Atovaquone', 'publication_year': 1995, 'publication_date': '1995-10-01', 'ids': {'openalex': 'https://openalex.org/W2171509350', 'doi': 'https://doi.org/10.1093/infdis/172.4.1042', 'mag': '2171509350', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7561178'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/infdis/172.4.1042', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109361832', 'display_name': 'Walter T. Hughes', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1313298211', 'display_name': "St. Jude Children's Research Hospital", 'ror': 'https://ror.org/02r3e0967', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1313298211', 'https://openalex.org/I2802152183']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'W. T. Hughes', 'raw_affiliation_strings': ["Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee"], 'affiliations': [{'raw_affiliation_string': "Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee", 'institution_ids': ['https://openalex.org/I1313298211']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006265191', 'display_name': 'Helieh S. Oz', 'orcid': 'https://orcid.org/0000-0002-4191-0858'}, 'institutions': [{'id': 'https://openalex.org/I1313298211', 'display_name': "St. Jude Children's Research Hospital", 'ror': 'https://ror.org/02r3e0967', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1313298211', 'https://openalex.org/I2802152183']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'H. S. Oz', 'raw_affiliation_strings': ["Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee"], 'affiliations': [{'raw_affiliation_string': "Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee", 'institution_ids': ['https://openalex.org/I1313298211']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5006265191'], 'corresponding_institution_ids': ['https://openalex.org/I1313298211'], 'apc_list': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.757, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.864147, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '172', 'issue': '4', 'first_page': '1042', 'last_page': '1046'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10296', 'display_name': 'Vector-borne infectious diseases', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10296', 'display_name': 'Vector-borne infectious diseases', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11641', 'display_name': 'Insect and Pesticide Research', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/atovaquone', 'display_name': 'Atovaquone', 'score': 0.99748385}, {'id': 'https://openalex.org/keywords/quinine', 'display_name': 'Quinine', 'score': 0.5153224}], 'concepts': [{'id': 'https://openalex.org/C2779124865', 'wikidata': 'https://www.wikidata.org/wiki/Q418179', 'display_name': 'Atovaquone', 'level': 4, 'score': 0.99748385}, {'id': 'https://openalex.org/C2775867548', 'wikidata': 'https://www.wikidata.org/wiki/Q1897162', 'display_name': 'Parasitemia', 'level': 4, 'score': 0.9297391}, {'id': 'https://openalex.org/C2778145968', 'wikidata': 'https://www.wikidata.org/wiki/Q797668', 'display_name': 'Babesiosis', 'level': 2, 'score': 0.8673305}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5928469}, {'id': 'https://openalex.org/C2777458120', 'wikidata': 'https://www.wikidata.org/wiki/Q422273', 'display_name': 'Clindamycin', 'level': 3, 'score': 0.5337701}, {'id': 'https://openalex.org/C180032290', 'wikidata': 'https://www.wikidata.org/wiki/Q1664296', 'display_name': 'Inoculation', 'level': 2, 'score': 0.52177674}, {'id': 'https://openalex.org/C2777617192', 'wikidata': 'https://www.wikidata.org/wiki/Q189522', 'display_name': 'Quinine', 'level': 3, 'score': 0.5153224}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.34238988}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.2913074}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.27546042}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.25376385}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.20949066}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.14056385}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.12245166}], 'mesh': [{'descriptor_ui': 'D000981', 'descriptor_name': 'Antiprotozoal Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001404', 'descriptor_name': 'Babesiosis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D001404', 'descriptor_name': 'Babesiosis', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D009285', 'descriptor_name': 'Naphthoquinones', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000981', 'descriptor_name': 'Antiprotozoal Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053626', 'descriptor_name': 'Atovaquone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001404', 'descriptor_name': 'Babesiosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018890', 'descriptor_name': 'Chemoprevention', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006224', 'descriptor_name': 'Cricetinae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003907', 'descriptor_name': 'Dexamethasone', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003907', 'descriptor_name': 'Dexamethasone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005069', 'descriptor_name': 'Evaluation Studies as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007165', 'descriptor_name': 'Immunosuppression Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009285', 'descriptor_name': 'Naphthoquinones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018512', 'descriptor_name': 'Parasitemia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D018512', 'descriptor_name': 'Parasitemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/infdis/172.4.1042', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7561178', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.85, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W1510118219', 'https://openalex.org/W1964281454', 'https://openalex.org/W1965527205', 'https://openalex.org/W1975354132', 'https://openalex.org/W1975571289', 'https://openalex.org/W1988190564', 'https://openalex.org/W1990424579', 'https://openalex.org/W1998122502', 'https://openalex.org/W1998597427', 'https://openalex.org/W2005117309', 'https://openalex.org/W2009509605', 'https://openalex.org/W2013684336', 'https://openalex.org/W2014126586', 'https://openalex.org/W2024400855', 'https://openalex.org/W2025781604', 'https://openalex.org/W2066610950', 'https://openalex.org/W2124048530', 'https://openalex.org/W2236844774', 'https://openalex.org/W2333137102', 'https://openalex.org/W2342056110', 'https://openalex.org/W2418499960', 'https://openalex.org/W25308852', 'https://openalex.org/W267355493'], 'related_works': ['https://openalex.org/W4289844161', 'https://openalex.org/W4220840436', 'https://openalex.org/W3200888103', 'https://openalex.org/W3016015433', 'https://openalex.org/W2404626380', 'https://openalex.org/W2391784610', 'https://openalex.org/W2340249602', 'https://openalex.org/W2331200474', 'https://openalex.org/W2171509350', 'https://openalex.org/W1977597012'], 'abstract_inverted_index': {'Atovaquone': [0], 'was': [1, 14, 78, 88, 104], 'evaluated': [2], 'for': [3, 24, 133], 'the': [4, 107], 'prevention': [5], 'and': [6, 22, 101, 120, 141], 'treatment': [7, 87], 'of': [8, 18, 29, 47, 52, 67, 73, 98, 109, 115, 122, 138], 'babesiosis': [9, 137], 'in': [10, 59, 96, 106, 136], 'hamsters.': [11], 'When': [12, 86], 'atovaquone': [13, 62, 95, 130], 'administered': [15], 'before': [16], 'inoculation': [17], '10(6)': [19], 'Babesia': [20], 'microti': [21], 'continued': [23], '8': [25], 'days': [26, 43, 72], 'thereafter,': [27], '9': [28], '10': [30, 118], 'hamsters': [31], 'survived': [32], 'beyond': [33], '54': [34, 71], 'days,': [35], 'but': [36, 61, 81], 'all': [37, 110], 'untreated': [38, 123], 'controls': [39], 'died': [40], 'within': [41], '12': [42], 'after': [44], 'inoculation.': [45], 'Quantitation': [46], 'parasitemia': [48, 92], 'showed': [49], 'a': [50], 'mean': [51], '75%': [53], 'erythrocytes': [54, 69], 'parasitized': [55, 68], 'by': [56], 'day': [57], '5': [58], 'controls,': [60], 'recipients': [63], 'never': [64], 'exceeded': [65], '0.7%': [66], 'over': [70], 'observation.': [74], 'Clindamycin': [75], 'plus': [76], 'quinine': [77], 'also': [79], 'effective': [80, 105], 'less': [82], 'so': [83], 'than': [84], 'atovaquone.': [85], 'not': [89], 'started': [90], 'until': [91], 'became': [93], 'established,': [94], 'doses': [97], '300,': [99], '150,': [100], '80': [102], 'mg/kg/day': [103, 119], 'recovery': [108], 'animals': [111], 'compared': [112], 'with': [113], '50%': [114], 'those': [116], 'receiving': [117], '10%': [121], 'controls.': [124], 'With': [125], 'its': [126], 'remarkable': [127], 'safety': [128], 'record,': [129], 'offers': [131], 'promise': [132], 'clinical': [134], 'trials': [135], 'both': [139], 'humans': [140], 'lower': [142], 'animals.': [143]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2171509350', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-08T21:20:36.039480', 'created_date': '2016-06-24'}