Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2170401510', 'doi': 'https://doi.org/10.2337/db09-1564', 'title': 'Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats', 'display_name': 'Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats', 'publication_year': 2010, 'publication_date': '2010-07-09', 'ids': {'openalex': 'https://openalex.org/W2170401510', 'doi': 'https://doi.org/10.2337/db09-1564', 'mag': '2170401510', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20622169', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3279561'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2337/db09-1564', 'pdf_url': 'https://diabetes.diabetesjournals.org/content/diabetes/59/10/2653.full.pdf', 'source': {'id': 'https://openalex.org/S129060628', 'display_name': 'Diabetes', 'issn_l': '0012-1797', 'issn': ['0012-1797', '1939-327X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320274', 'host_organization_name': 'American Diabetes Association', 'host_organization_lineage': ['https://openalex.org/P4310320274'], 'host_organization_lineage_names': ['American Diabetes Association'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://diabetes.diabetesjournals.org/content/diabetes/59/10/2653.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073614725', 'display_name': 'Bethany P. Cummings', 'orcid': 'https://orcid.org/0000-0002-0610-9870'}, 'institutions': [{'id': 'https://openalex.org/I84218800', 'display_name': 'University of California, Davis', 'ror': 'https://ror.org/05rrcem69', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84218800']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Bethany P. Cummings', 'raw_affiliation_strings': ['Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'Department of Nutrition, University of California, Davis, Davis, California;'], 'affiliations': [{'raw_affiliation_string': 'Department of Nutrition, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}, {'raw_affiliation_string': 'Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056635157', 'display_name': 'Kimber L. Stanhope', 'orcid': 'https://orcid.org/0000-0002-2474-0914'}, 'institutions': [{'id': 'https://openalex.org/I84218800', 'display_name': 'University of California, Davis', 'ror': 'https://ror.org/05rrcem69', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84218800']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kimber L. Stanhope', 'raw_affiliation_strings': ['Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'Department of Nutrition, University of California, Davis, Davis, California;'], 'affiliations': [{'raw_affiliation_string': 'Department of Nutrition, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}, {'raw_affiliation_string': 'Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081546127', 'display_name': 'James L. Graham', 'orcid': 'https://orcid.org/0000-0001-6507-8149'}, 'institutions': [{'id': 'https://openalex.org/I84218800', 'display_name': 'University of California, Davis', 'ror': 'https://ror.org/05rrcem69', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84218800']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James L. Graham', 'raw_affiliation_strings': ['Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'Department of Nutrition, University of California, Davis, Davis, California;'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}, {'raw_affiliation_string': 'Department of Nutrition, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109548097', 'display_name': 'Denis G. Baskin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210094549', 'display_name': 'VA Puget Sound Health Care System', 'ror': 'https://ror.org/00ky3az31', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210094549', 'https://openalex.org/I4210138024']}, {'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Denis G. Baskin', 'raw_affiliation_strings': ['Research and Development Service, Department of Veterans Affairs Puget Sound Health Care System, Seattle, Washington, and the Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, Washington;'], 'affiliations': [{'raw_affiliation_string': 'Research and Development Service, Department of Veterans Affairs Puget Sound Health Care System, Seattle, Washington, and the Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, Washington;', 'institution_ids': ['https://openalex.org/I4210094549', 'https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010282554', 'display_name': 'Steven C. Griffen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I84218800', 'display_name': 'University of California, Davis', 'ror': 'https://ror.org/05rrcem69', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84218800']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Steven C. Griffen', 'raw_affiliation_strings': ['Department of Internal Medicine, University of California, Davis, Sacramento, California;'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, University of California, Davis, Sacramento, California;', 'institution_ids': ['https://openalex.org/I84218800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110789696', 'display_name': 'Cecilia Nilsson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189090001', 'display_name': 'Novo Nordisk (Denmark)', 'ror': 'https://ror.org/0435rc536', 'country_code': 'DK', 'type': 'company', 'lineage': ['https://openalex.org/I189090001', 'https://openalex.org/I2801134892', 'https://openalex.org/I4210159963']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Cecilia Nilsson', 'raw_affiliation_strings': ['Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;'], 'affiliations': [{'raw_affiliation_string': 'Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;', 'institution_ids': ['https://openalex.org/I189090001']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111701808', 'display_name': 'Anette Sams', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189090001', 'display_name': 'Novo Nordisk (Denmark)', 'ror': 'https://ror.org/0435rc536', 'country_code': 'DK', 'type': 'company', 'lineage': ['https://openalex.org/I189090001', 'https://openalex.org/I2801134892', 'https://openalex.org/I4210159963']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Anette Sams', 'raw_affiliation_strings': ['Diabetes Inflammation Department, Novo Nordisk, Gentofte, Denmark.'], 'affiliations': [{'raw_affiliation_string': 'Diabetes Inflammation Department, Novo Nordisk, Gentofte, Denmark.', 'institution_ids': ['https://openalex.org/I189090001']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088627727', 'display_name': 'Lotte Bjerre Knudsen', 'orcid': 'https://orcid.org/0000-0002-2439-7116'}, 'institutions': [{'id': 'https://openalex.org/I189090001', 'display_name': 'Novo Nordisk (Denmark)', 'ror': 'https://ror.org/0435rc536', 'country_code': 'DK', 'type': 'company', 'lineage': ['https://openalex.org/I189090001', 'https://openalex.org/I2801134892', 'https://openalex.org/I4210159963']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Lotte B. Knudsen', 'raw_affiliation_strings': ['Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;'], 'affiliations': [{'raw_affiliation_string': 'Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;', 'institution_ids': ['https://openalex.org/I189090001']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064830959', 'display_name': 'Kirsten Raun', 'orcid': 'https://orcid.org/0000-0001-7605-8215'}, 'institutions': [{'id': 'https://openalex.org/I189090001', 'display_name': 'Novo Nordisk (Denmark)', 'ror': 'https://ror.org/0435rc536', 'country_code': 'DK', 'type': 'company', 'lineage': ['https://openalex.org/I189090001', 'https://openalex.org/I2801134892', 'https://openalex.org/I4210159963']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Kirsten Raun', 'raw_affiliation_strings': ['Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;'], 'affiliations': [{'raw_affiliation_string': 'Biology and Pharmacology Management, Novo Nordisk, Maaloev, Denmark;', 'institution_ids': ['https://openalex.org/I189090001']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5034829692', 'display_name': 'Peter J. Havel', 'orcid': 'https://orcid.org/0000-0003-3652-8301'}, 'institutions': [{'id': 'https://openalex.org/I84218800', 'display_name': 'University of California, Davis', 'ror': 'https://ror.org/05rrcem69', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I84218800']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Peter J. Havel', 'raw_affiliation_strings': ['Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'Department of Nutrition, University of California, Davis, Davis, California;'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}, {'raw_affiliation_string': 'Department of Nutrition, University of California, Davis, Davis, California;', 'institution_ids': ['https://openalex.org/I84218800']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5034829692'], 'corresponding_institution_ids': ['https://openalex.org/I84218800'], 'apc_list': None, 'apc_paid': None, 'fwci': 4.402, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 69, 'citation_normalized_percentile': {'value': 0.999908, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '59', 'issue': '10', 'first_page': '2653', 'last_page': '2661'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10401', 'display_name': 'Diabetes Treatment and Management', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10401', 'display_name': 'Diabetes Treatment and Management', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic function and diabetes', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11339', 'display_name': 'Metabolism, Diabetes, and Cancer', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2781308992', 'wikidata': 'https://www.wikidata.org/wiki/Q2526479', 'display_name': 'Liraglutide', 'level': 4, 'score': 0.99855727}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.80059457}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.7936355}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7285965}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.65540105}, {'id': 'https://openalex.org/C2776398474', 'wikidata': 'https://www.wikidata.org/wiki/Q424611', 'display_name': 'Glucagon-like peptide-1', 'level': 4, 'score': 0.54088575}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.5046941}, {'id': 'https://openalex.org/C2777180221', 'wikidata': 'https://www.wikidata.org/wiki/Q3025883', 'display_name': 'Type 2 diabetes', 'level': 3, 'score': 0.4940584}, {'id': 'https://openalex.org/C2778563252', 'wikidata': 'https://www.wikidata.org/wiki/Q170617', 'display_name': 'Glucagon', 'level': 3, 'score': 0.48780516}], 'mesh': [{'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D052216', 'descriptor_name': 'Glucagon-Like Peptide 1', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D017668', 'descriptor_name': 'Age of Onset', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001835', 'descriptor_name': 'Body Weight', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001835', 'descriptor_name': 'Body Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004231', 'descriptor_name': 'Diuresis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004231', 'descriptor_name': 'Diuresis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D052216', 'descriptor_name': 'Glucagon-Like Peptide 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052216', 'descriptor_name': 'Glucagon-Like Peptide 1', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006442', 'descriptor_name': 'Glycated Hemoglobin A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006442', 'descriptor_name': 'Glycated Hemoglobin A', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006943', 'descriptor_name': 'Hyperglycemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006943', 'descriptor_name': 'Hyperglycemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000069450', 'descriptor_name': 'Liraglutide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010179', 'descriptor_name': 'Pancreas', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010179', 'descriptor_name': 'Pancreas', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D010179', 'descriptor_name': 'Pancreas', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D010179', 'descriptor_name': 'Pancreas', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2337/db09-1564', 'pdf_url': 'https://diabetes.diabetesjournals.org/content/diabetes/59/10/2653.full.pdf', 'source': {'id': 'https://openalex.org/S129060628', 'display_name': 'Diabetes', 'issn_l': '0012-1797', 'issn': ['0012-1797', '1939-327X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320274', 'host_organization_name': 'American Diabetes Association', 'host_organization_lineage': ['https://openalex.org/P4310320274'], 'host_organization_lineage_names': ['American Diabetes Association'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3279561', 'pdf_url': 'https://europepmc.org/articles/pmc3279561?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://escholarship.org/uc/item/07c0248r', 'pdf_url': 'https://escholarship.org/content/qt07c0248r/qt07c0248r.pdf?t=pttahz', 'source': {'id': 'https://openalex.org/S4306400115', 'display_name': 'eScholarship (California Digital Library)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I2801248553', 'host_organization_name': 'California Digital Library', 'host_organization_lineage': ['https://openalex.org/I2801248553'], 'host_organization_lineage_names': ['California Digital Library'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279561', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20622169', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2337/db09-1564', 'pdf_url': 'https://diabetes.diabetesjournals.org/content/diabetes/59/10/2653.full.pdf', 'source': {'id': 'https://openalex.org/S129060628', 'display_name': 'Diabetes', 'issn_l': '0012-1797', 'issn': ['0012-1797', '1939-327X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320274', 'host_organization_name': 'American Diabetes Association', 'host_organization_lineage': ['https://openalex.org/P4310320274'], 'host_organization_lineage_names': ['American Diabetes Association'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/7', 'display_name': 'Affordable and clean energy', 'score': 0.61}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1888368658', 'https://openalex.org/W1905803407', 'https://openalex.org/W1975756049', 'https://openalex.org/W1986331352', 'https://openalex.org/W1996033370', 'https://openalex.org/W2003604699', 'https://openalex.org/W2008411184', 'https://openalex.org/W2011823591', 'https://openalex.org/W2013851956', 'https://openalex.org/W2021022471', 'https://openalex.org/W2048981028', 'https://openalex.org/W2067314875', 'https://openalex.org/W2068183831', 'https://openalex.org/W2070271057', 'https://openalex.org/W2071835038', 'https://openalex.org/W2076805031', 'https://openalex.org/W2080128749', 'https://openalex.org/W2084948079', 'https://openalex.org/W2088987697', 'https://openalex.org/W2090898804', 'https://openalex.org/W2098459806', 'https://openalex.org/W2102752610', 'https://openalex.org/W2108282017', 'https://openalex.org/W2108672863', 'https://openalex.org/W2109327370', 'https://openalex.org/W2109432892', 'https://openalex.org/W2113544353', 'https://openalex.org/W2114416343', 'https://openalex.org/W2119804129', 'https://openalex.org/W2123951330', 'https://openalex.org/W2128181185', 'https://openalex.org/W2132956041', 'https://openalex.org/W2133545915', 'https://openalex.org/W2137352234', 'https://openalex.org/W2138290933', 'https://openalex.org/W2145329719', 'https://openalex.org/W2146156707', 'https://openalex.org/W2156689802', 'https://openalex.org/W2158342810', 'https://openalex.org/W2160001758', 'https://openalex.org/W2168526937', 'https://openalex.org/W2170606300', 'https://openalex.org/W2409309504'], 'related_works': ['https://openalex.org/W4300433033', 'https://openalex.org/W4223466080', 'https://openalex.org/W4206203435', 'https://openalex.org/W3030120986', 'https://openalex.org/W2490399744', 'https://openalex.org/W2370701043', 'https://openalex.org/W2334271056', 'https://openalex.org/W2109274758', 'https://openalex.org/W2080010254', 'https://openalex.org/W2014914257'], 'abstract_inverted_index': {'OBJECTIVE': [0], 'The': [1], 'efficacy': [2], 'of': [3, 21, 36, 73, 85, 93, 176, 229], 'liraglutide,': [4], 'a': [5, 19], 'human': [6], 'glucagon-like': [7], 'peptide-1': [8], '(GLP-1)': [9], 'analog,': [10], 'to': [11, 65, 69, 131, 173], 'prevent': [12], 'or': [13, 55], 'delay': [14], 'diabetes': [15, 79, 100, 146, 230], 'in': [16, 113, 231], 'UCD-T2DM': [17, 232], 'rats,': [18], 'model': [20], 'polygenic': [22], 'obese': [23], 'type': [24], '2': [25, 34], 'diabetes,': [26], 'was': [27], 'investigated.': [28], 'RESEARCH': [29], 'DESIGN': [30], 'AND': [31], 'METHODS': [32], 'At': [33], 'months': [35, 92, 152, 164, 175], 'age,': [37, 177], 'male': [38], 'rats': [39, 61, 233], 'were': [40, 62, 76, 88, 111], 'divided': [41], 'into': [42], 'three': [43], 'groups:': [44], 'control,': [45], 'food-restricted,': [46], 'and': [47, 107, 119, 159, 180, 187, 204, 210, 215, 238, 241, 249], 'liraglutide.': [48], 'Animals': [49], 'received': [50], 'liraglutide': [51, 139, 181], '(0.2': [52], 'mg/kg': [53], 's.c.)': [54], 'vehicle': [56], 'injections': [57], 'twice': [58], 'daily.': [59], 'Restricted': [60], 'food': [63, 126], 'restricted': [64, 118, 167, 211], 'equalize': [66], 'body': [67, 104, 135, 239], 'weights': [68], 'liraglutide-treated': [70, 120, 129, 196, 216], 'rats.': [71, 121], 'Half': [72], 'the': [74, 82, 86, 133, 227], 'animals': [75, 87, 115, 123, 130, 168, 197, 217], 'followed': [77], 'until': [78], 'onset,': [80], 'whereas': [81], 'other': [83], 'half': [84], 'killed': [89], 'at': [90], '6.5': [91], 'age': [94], 'for': [95], 'tissue': [96], 'collection.': [97], 'RESULTS': [98], 'Before': [99], 'onset': [101, 147], 'energy': [102, 141, 178, 236], 'intake,': [103], 'weight,': [105, 240], 'adiposity,': [106], 'liver': [108], 'triglyceride': [109], 'content': [110], 'higher': [112], 'control': [114, 155, 192, 209], 'compared': [116, 153, 165, 190, 206], 'with': [117, 154, 166, 191, 207], 'Energy-restricted': [122], 'had': [124], 'lower': [125, 199], 'intake': [127, 237], 'than': [128], 'maintain': [132], 'same': [134], 'weights,': [136], 'suggesting': [137], 'that': [138], 'increases': [140], 'expenditure.': [142], 'Liraglutide': [143, 224], 'treatment': [144, 182, 225], 'delayed': [145], 'by': [148, 160, 234, 242], '4.1': [149], '±': [150, 162], '0.8': [151, 163], '(P': [156, 169], '<': [157, 170], '0.0001)': [158], '1.3': [161], '0.05).': [171], 'Up': [172], '6': [174], 'restriction': [179], 'lowered': [183], 'fasting': [184, 200], 'plasma': [185, 201], 'glucose': [186], 'A1C': [188], 'concentrations': [189], 'animals.': [193, 212], 'In': [194], 'contrast,': [195], 'exhibited': [198, 218], 'insulin,': [202], 'glucagon,': [203], 'triglycerides': [205], 'both': [208], 'Furthermore,': [213], 'energy-restricted': [214], 'more': [219], 'normal': [220], 'islet': [221, 251], 'morphology.': [222, 252], 'CONCLUSIONS': [223], 'delays': [226], 'development': [228], 'reducing': [235], 'improving': [243, 246], 'insulin': [244], 'sensitivity,': [245], 'lipid': [247], 'profiles,': [248], 'maintaining': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2170401510', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-08T17:27:49.104376', 'created_date': '2016-06-24'}