Publication Information

{'id': 'https://openalex.org/W2170197815', 'doi': 'https://doi.org/10.1161/01.hyp.35.3.e10', 'title': 'Much Ado About Nothing, or Much to Do About Something? The Continuing Controversy Over the Role of Uric Acid in Cardiovascular Disease', 'display_name': 'Much Ado About Nothing, or Much to Do About Something? The Continuing Controversy Over the Role of Uric Acid in Cardiovascular Disease', 'publication_year': 2000, 'publication_date': '2000-03-01', 'ids': {'openalex': 'https://openalex.org/W2170197815', 'doi': 'https://doi.org/10.1161/01.hyp.35.3.e10', 'mag': '2170197815', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10720608'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.hyp.35.3.e10', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.35.3.e10', 'source': {'id': 'https://openalex.org/S67880631', 'display_name': 'Hypertension', 'issn_l': '0194-911X', 'issn': ['0194-911X', '1524-4563'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.35.3.e10', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004471228', 'display_name': 'Richard J. Johnson', 'orcid': 'https://orcid.org/0000-0003-3312-8193'}, 'institutions': [{'id': 'https://openalex.org/I2801852214', 'display_name': 'University of Washington Medical Center', 'ror': 'https://ror.org/00wbzw723', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801852214']}, {'id': 'https://openalex.org/I1282676378', 'display_name': 'Providence Sacred Heart Medical Center', 'ror': 'https://ror.org/01wc5x922', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1282676378', 'https://openalex.org/I94396219']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard J. Johnson', 'raw_affiliation_strings': ['Richard J. Johnson University of Washington Medical Center, Seattle, Washington, The Heart Institute of Spokane, Spokane, Washington'], 'affiliations': [{'raw_affiliation_string': 'Richard J. Johnson University of Washington Medical Center, Seattle, Washington, The Heart Institute of Spokane, Spokane, Washington', 'institution_ids': ['https://openalex.org/I2801852214', 'https://openalex.org/I1282676378']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5046793050', 'display_name': 'Katherine R. Tuttle', 'orcid': 'https://orcid.org/0000-0002-2235-0103'}, 'institutions': [{'id': 'https://openalex.org/I1282676378', 'display_name': 'Providence Sacred Heart Medical Center', 'ror': 'https://ror.org/01wc5x922', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1282676378', 'https://openalex.org/I94396219']}, {'id': 'https://openalex.org/I2801852214', 'display_name': 'University of Washington Medical Center', 'ror': 'https://ror.org/00wbzw723', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801852214']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Katherine R. Tuttle', 'raw_affiliation_strings': ['Katherine R. Tuttle University of Washington Medical Center, Seattle, Washington, The Heart Institute of Spokane, Spokane, Washington'], 'affiliations': [{'raw_affiliation_string': 'Katherine R. Tuttle University of Washington Medical Center, Seattle, Washington, The Heart Institute of Spokane, Spokane, Washington', 'institution_ids': ['https://openalex.org/I1282676378', 'https://openalex.org/I2801852214']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 45, 'citation_normalized_percentile': {'value': 0.934426, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '35', 'issue': '3', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11139', 'display_name': 'Gout, Hyperuricemia, Uric Acid', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11139', 'display_name': 'Gout, Hyperuricemia, Uric Acid', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11207', 'display_name': 'Alcohol Consumption and Health Effects', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12600', 'display_name': 'Eosinophilic Disorders and Syndromes', 'score': 0.9826, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nothing', 'display_name': 'Nothing', 'score': 0.67522043}], 'concepts': [{'id': 'https://openalex.org/C136815107', 'wikidata': 'https://www.wikidata.org/wiki/Q154242', 'display_name': 'Nothing', 'level': 2, 'score': 0.67522043}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.6286973}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.51941514}, {'id': 'https://openalex.org/C2779881121', 'wikidata': 'https://www.wikidata.org/wiki/Q105522', 'display_name': 'Uric acid', 'level': 2, 'score': 0.5145073}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.41698003}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28274342}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.26911682}, {'id': 'https://openalex.org/C111472728', 'wikidata': 'https://www.wikidata.org/wiki/Q9471', 'display_name': 'Epistemology', 'level': 1, 'score': 0.16435164}], 'mesh': [{'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D014527', 'descriptor_name': 'Uric Acid', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015986', 'descriptor_name': 'Confounding Factors, Epidemiologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015999', 'descriptor_name': 'Multivariate Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014527', 'descriptor_name': 'Uric Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.hyp.35.3.e10', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.35.3.e10', 'source': {'id': 'https://openalex.org/S67880631', 'display_name': 'Hypertension', 'issn_l': '0194-911X', 'issn': ['0194-911X', '1524-4563'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10720608', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.hyp.35.3.e10', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.35.3.e10', 'source': {'id': 'https://openalex.org/S67880631', 'display_name': 'Hypertension', 'issn_l': '0194-911X', 'issn': ['0194-911X', '1524-4563'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1551875034', 'https://openalex.org/W161697350', 'https://openalex.org/W1948619662', 'https://openalex.org/W1969124832', 'https://openalex.org/W1973603453', 'https://openalex.org/W1975219692', 'https://openalex.org/W1975444523', 'https://openalex.org/W1975676421', 'https://openalex.org/W1988648779', 'https://openalex.org/W1994374444', 'https://openalex.org/W1997145262', 'https://openalex.org/W2002373438', 'https://openalex.org/W2015518189', 'https://openalex.org/W2015697722', 'https://openalex.org/W2022202946', 'https://openalex.org/W2027710201', 'https://openalex.org/W2036244266', 'https://openalex.org/W2043031422', 'https://openalex.org/W2045743391', 'https://openalex.org/W2047236390', 'https://openalex.org/W2048127775', 'https://openalex.org/W2064280071', 'https://openalex.org/W2069730334', 'https://openalex.org/W2076691130', 'https://openalex.org/W2083721084', 'https://openalex.org/W2093707453', 'https://openalex.org/W2094334190', 'https://openalex.org/W2102783953', 'https://openalex.org/W2116874158', 'https://openalex.org/W2117111476', 'https://openalex.org/W2123114339', 'https://openalex.org/W2125681606', 'https://openalex.org/W2130198700', 'https://openalex.org/W2138064547', 'https://openalex.org/W2142311055', 'https://openalex.org/W2154219140', 'https://openalex.org/W2158088707', 'https://openalex.org/W2171243007', 'https://openalex.org/W2312946786', 'https://openalex.org/W2313390005', 'https://openalex.org/W2331492343', 'https://openalex.org/W4247938048', 'https://openalex.org/W4249144739', 'https://openalex.org/W4317707833', 'https://openalex.org/W99362486'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W3011492772', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2216420239', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455'], 'abstract_inverted_index': {'HomeHypertensionVol.': [0], '35,': [1, 4088], 'No.': [2], '3Much': [3], 'Ado': [4, 40], 'About': [5, 11, 41, 47], 'Nothing,': [6, 42], 'or': [7, 43, 434, 602, 753, 761, 1059, 1082, 1160, 1198, 1209, 1240, 1280, 1366, 2203, 2675, 3466], 'Much': [8, 44], 'to': [9, 30, 45, 125, 201, 212, 239, 243, 258, 272, 292, 335, 370, 459, 511, 521, 570, 578, 622, 639, 796, 824, 879, 904, 909, 917, 954, 1092, 1147, 1156, 1353, 1392, 1436, 1443, 1503, 1523, 1971, 2091, 2133, 2141, 2291, 2333, 2341, 2363, 2507, 2585, 2595, 2689, 2790, 2852, 2897, 2922, 3441, 4005], 'Do': [10, 46], 'Something?': [12, 48], 'The': [13, 49, 80, 100, 1481, 1741, 1799, 1871, 1923, 2208, 2602, 2684, 3225, 3583, 3609, 3741, 3898], 'Continuing': [14, 50], 'Controversy': [15, 51], 'Over': [16, 52], 'the': [17, 53, 112, 117, 142, 170, 208, 221, 224, 232, 266, 295, 310, 313, 325, 358, 413, 431, 435, 466, 484, 519, 530, 586, 623, 628, 654, 660, 664, 682, 697, 700, 726, 732, 768, 793, 811, 851, 859, 872, 894, 927, 948, 955, 963, 967, 989, 995, 999, 1003, 1011, 1021, 1024, 1035, 1049, 1072, 1120, 1127, 1130, 1133, 1144, 1162, 1168, 1192, 1247, 1291, 1304, 1348, 1360, 1378, 1380, 1383, 1388, 1396, 1425, 1429, 1444, 1448, 1451, 1455, 1557, 1622, 1667, 1919, 1934, 1964, 1972, 2056, 2099, 2120, 2142, 2171, 2193, 2196, 2221, 2228, 2254, 2271, 2292, 2315, 2342, 2346, 2349, 2387, 2391, 2413, 2418, 2422, 2467, 2479, 2484, 2495, 2593, 2624, 2640, 2692, 2699, 2706, 2720, 2733, 2744, 2749, 2765, 2778, 2811, 2826, 2871, 3129, 3195, 3492, 3615, 3660, 3919, 3958], 'Role': [18, 54, 3856], 'of': [19, 55, 74, 83, 94, 103, 207, 223, 309, 376, 408, 415, 437, 486, 536, 565, 589, 627, 653, 681, 684, 699, 710, 767, 858, 874, 896, 929, 959, 966, 1013, 1027, 1114, 1132, 1135, 1194, 1222, 1249, 1265, 1271, 1350, 1375, 1390, 1398, 1427, 1440, 1450, 1458, 1476, 1519, 1545, 1554, 1560, 1619, 1666, 1671, 1758, 1761, 1839, 1851, 1915, 1933, 1937, 1959, 1966, 1974, 2000, 2122, 2198, 2215, 2224, 2232, 2263, 2314, 2337, 2348, 2379, 2400, 2437, 2446, 2469, 2481, 2497, 2510, 2522, 2535, 2569, 2604, 2626, 2642, 2645, 2655, 2686, 2701, 2708, 2735, 2748, 2767, 2777, 2813, 2823, 2873, 2914, 2966, 3024, 3138, 3278, 3408, 3447, 3469, 3522, 3585, 3611, 3617, 3638, 3664, 3705, 3729, 3744, 3828, 3901, 3921, 3960, 4070, 4076], 'Uric': [20, 56, 1586, 3191, 3395, 3432, 3470, 3488, 3571, 3732, 3754, 3851], 'Acid': [21, 57, 3192, 3396, 3471, 3489, 3572, 3733, 3755, 3852], 'in': [22, 58, 149, 220, 284, 297, 353, 410, 430, 451, 471, 529, 659, 696, 717, 747, 816, 841, 893, 898, 1002, 1063, 1182, 1235, 1288, 1327, 1413, 1556, 1562, 1647, 1673, 1804, 1882, 1918, 1922, 2003, 2041, 2055, 2119, 2170, 2205, 2220, 2238, 2246, 2277, 2287, 2311, 2386, 2421, 2440, 2483, 2494, 2548, 2620, 2652, 2691, 2743, 2761, 2786, 2825, 2968, 3015, 3119, 3168, 3231, 3270, 3434, 3577, 3614, 3698, 3801, 3857, 3862, 3936, 3956], 'Cardiovascular': [23, 59, 3034, 3176], 'Disease': [24, 60, 3826], 'Free': [25], 'AccessOtherPDF/EPUBAboutView': [26], 'PDFView': [27], 'EPUBSections': [28], 'ToolsAdd': [29], 'favoritesDownload': [31], 'citationsTrack': [32], 'citationsPermissions': [33], 'ShareShare': [34], 'onFacebookTwitterLinked': [35], 'InMendeleyReddit': [36], 'Jump': [37], 'toFree': [38], 'AccessOtherPDF/EPUBMuch': [39], 'Richard': [61, 68], 'J.': [62, 69, 71, 1541], 'Johnson': [63, 72, 1655, 1817, 2167, 2295, 2574, 2853, 3188, 3222, 3315, 3368, 3392, 3429, 3457, 3485, 3565, 3606, 3788, 3840, 3996], 'and': [64, 87, 147, 166, 172, 193, 281, 403, 483, 504, 541, 597, 650, 676, 834, 907, 936, 985, 992, 998, 1100, 1116, 1219, 1258, 1263, 1324, 1344, 1347, 1474, 1479, 1525, 1543, 1548, 1625, 1644, 1669, 1677, 1728, 1732, 1734, 1787, 1823, 1842, 1848, 1867, 1913, 1961, 2023, 2036, 2063, 2066, 2069, 2161, 2168, 2174, 2285, 2296, 2321, 2373, 2417, 2453, 2478, 2547, 2575, 2613, 2782, 2854, 2869, 2878, 2890, 2958, 2963, 3008, 3033, 3109, 3157, 3163, 3175, 3187, 3194, 3221, 3235, 3261, 3267, 3314, 3321, 3327, 3367, 3391, 3397, 3428, 3461, 3484, 3491, 3516, 3533, 3538, 3567, 3574, 3605, 3631, 3636, 3654, 3659, 3662, 3687, 3692, 3723, 3756, 3761, 3787, 3803, 3817, 3822, 3846, 3860, 3880, 3887, 3892, 3912, 3928, 3950, 3995, 4008, 4057, 4067], 'Katherine': [65, 88], 'R.': [66, 89, 91], 'Tuttle': [67, 92, 1813, 2169, 2175, 3913], 'JohnsonRichard': [70], 'University': [73, 93], 'Washington': [75, 86, 95, 106], 'Medical': [76, 96], 'Center,': [77, 97], 'Seattle,': [78, 98], 'Washington,': [79, 99], 'Heart': [81, 101, 1483, 1887, 2273, 2415, 3706], 'Institute': [82, 102], 'Spokane,': [84, 85, 104, 105], 'TuttleKatherine': [90], 'Originally': [107, 4095], 'published1': [108], 'Mar': [109], '2000https://doi.org/10.1161/01.HYP.35.3.e10Hypertension.': [110], '2000;35:e10To': [111], 'Editor:Recently,': [113], 'an': [114, 127, 173, 245, 259, 274, 494, 613, 641, 805, 867, 938, 1103, 1111, 1136, 1276, 1332, 1801, 2009, 2184, 2473, 2491, 2757, 2774, 2860, 3020, 3438, 4031], 'update': [115], 'from': [116, 725, 792, 802, 808, 922, 1410, 1621, 1737, 2270, 2863, 2887], 'Framingham': [118, 209, 728, 809, 1482, 1872], 'study': [119, 210, 634, 795, 829, 1559, 2255, 2667], 'could': [120, 543, 608, 1088, 1106, 3018], 'not': [121, 185, 197, 236, 332, 340, 351, 367, 544, 790, 908, 915, 1048, 1060, 1178, 1200, 2103, 2459, 2670, 2713, 2833, 2848, 4030], 'find': [122, 831], 'uric': [123, 136, 182, 241, 270, 496, 637, 694, 741, 748, 864, 881, 886, 1036, 1195, 1229, 1250, 1273, 1297, 1314, 1334, 1361, 1472, 1521, 1614, 1642, 1821, 1846, 1906, 2043, 2078, 2105, 2113, 2181, 2225, 2264, 2283, 2305, 2319, 2371, 2394, 2438, 2447, 2470, 2501, 2516, 2564, 2605, 2646, 2754, 2779, 2814, 2899, 3013, 3114, 3228, 3612, 3792, 3885, 3922, 4000, 4027], 'acid': [124, 137, 183, 242, 271, 497, 638, 742, 749, 865, 882, 887, 1037, 1196, 1230, 1251, 1274, 1298, 1315, 1335, 1362, 1473, 1522, 1615, 1643, 1822, 1847, 2044, 2079, 2106, 2114, 2182, 2226, 2265, 2284, 2306, 2320, 2372, 2395, 2439, 2448, 2471, 2502, 2517, 2565, 2606, 2647, 2755, 2815, 2900, 3014, 3131, 3433, 3613, 3886, 3923, 4001, 4028], 'be': [126, 198, 213, 218, 244, 273, 341, 368, 393, 422, 444, 508, 545, 571, 640, 756, 1078, 1093, 1107, 1171, 1201, 1437, 2134, 2334, 2526, 2582, 2739, 2784, 3019], 'independent': [128, 246, 275, 334, 375, 394, 517, 614, 642, 835, 868, 1112, 1137, 1277, 2591, 2758, 4032], 'risk': [129, 143, 188, 247, 276, 329, 359, 385, 419, 441, 461, 514, 523, 549, 615, 626, 689, 702, 782, 812, 836, 849, 869, 1056, 1138, 1254, 1278, 1320, 1340, 1397, 1475, 1544, 1589, 1914, 2051, 2082, 2127, 2186, 2588, 2597, 2661, 2703, 2722, 2731, 2759, 2905, 3022, 4033], 'factor': [130, 189, 248, 277, 330, 386, 420, 442, 515, 616, 690, 870, 1076, 1151, 1163, 1255, 1394, 1433, 1445, 1590, 2052, 2083, 2187, 2330, 2343, 2589, 2760, 3023, 3796, 4034], 'for': [131, 144, 157, 190, 249, 278, 289, 294, 387, 399, 551, 644, 783, 813, 837, 846, 924, 1119, 1303, 1321, 1341, 1373, 1496, 1591, 1963, 2084, 2094, 2136, 2145, 2188, 2217, 2433, 2658, 2705, 2715, 2728, 2798, 2817, 2865, 2918, 3125, 3133, 3227, 3325, 3918, 4035], 'cardiovascular': [132, 145, 191, 203, 250, 279, 785, 814, 839, 934, 1030, 1165, 1289, 1322, 1343, 1477, 1497, 1546, 1645, 1675, 1916, 2048, 3532, 3619, 3804, 3888, 3926, 4007], 'disease.1': [133], 'While': [134, 226, 787], 'serum': [135, 594, 1520, 1766, 1845, 2042, 2077, 2370, 2500], 'levels': [138, 883, 1038, 1363], 'correlated': [139], 'significantly': [140], 'with': [141, 473, 477, 498, 591, 712, 774, 799, 818, 1098, 1124, 1224, 1237, 1318, 1331, 1420, 1454, 1910, 2005, 2060, 2109, 2266, 2355, 2405, 2428, 2449, 2573, 2607, 2629, 2724, 3233, 3579, 3735, 3797], 'events': [146, 280, 1646, 1917], 'mortality': [148, 556, 906, 935, 1031, 1091, 1115, 1122, 1184, 1524, 1736, 2721], 'women,': [150], 'this': [151, 349, 452, 671, 718, 977, 2138, 2233], 'relationship': [152, 2781], 'became': [153], 'insignificant': [154], 'after': [155, 2539, 2726, 3695], 'factoring': [156, 930, 2874], '11': [158], 'additional': [159, 920, 2861], 'variables': [160, 861, 2688, 2751], 'including': [161, 988], 'hypertension,': [162, 592, 897, 960, 1674, 2608, 3925], 'body': [163, 1457], 'mass': [164], 'index,': [165], 'diuretic': [167, 1125, 1351, 1911, 2771, 2793, 2866], 'use.1': [168], 'Both': [169], 'authors1': [171], 'accompanying': [174, 2172, 2745], 'editorial2': [175], 'interpreted': [176], 'these': [177, 298, 566, 2206, 2627, 2678], 'findings': [178, 1409], 'as': [179, 231, 301, 417, 439, 547, 575, 612, 692, 866, 1080, 1174, 1252, 1306, 2045, 2147, 2472, 2529, 2566, 2756, 2901, 4002], 'showing': [180], 'that': [181, 194, 327, 337, 348, 372, 468, 666, 714, 731, 862, 946, 982, 1010, 1045, 1053, 1143, 1149, 1158, 1216, 1227, 1246, 1295, 2076, 2088, 2180, 2304, 2578, 2752, 2830, 2879], 'is': [184, 211, 320, 331, 350, 383, 397, 428, 448, 456, 475, 516, 525, 585, 720, 730, 789, 980, 1047, 1110, 1152, 1155, 1214, 1275, 1294, 1299, 1316, 1357, 1385, 1418, 1434, 2080, 2102, 2107, 2132, 2183, 2200, 2331, 2442, 2456, 2518, 2590, 2599, 2632, 2695, 2773, 2795, 2880, 4029], 'a': [186, 328, 384, 418, 440, 489, 513, 679, 723, 738, 832, 1150, 1186, 1204, 1253, 1285, 1300, 1393, 1406, 1432, 1438, 1551, 1588, 1968, 2046, 2081, 2086, 2116, 2125, 2212, 2329, 2335, 2338, 2366, 2434, 2505, 2519, 2567, 2587, 2633, 2643, 2653, 2665, 2796, 2820, 2902, 3120, 3126, 3442, 3854, 4003, 4071], 'true': [187, 352], 'disease': [192, 402, 500, 555, 815, 840, 1323, 1399, 1423, 1478, 1547, 2049], 'it': [195, 338, 389, 396, 619, 788, 979, 1046, 1213, 1283, 1307], 'should': [196, 323, 339, 1067, 1077], 'routinely': [199], 'measured': [200], 'assess': [202], 'risk.The': [204], 'careful': [205, 2252], 'analysis': [206, 733, 769, 807, 1618], 'commended,': [214], 'but': [215, 307, 961, 1057, 2111, 2242, 2458, 2556], 'one': [216, 234, 322, 365, 687, 763, 857, 913, 1140, 1422, 1499, 2637, 2711, 2747, 2857], 'must': [217, 1446, 2344, 2738, 2783], 'cautious': [219], 'interpretation': [222, 1131], 'findings.': [225], 'some': [227, 766], 'epidemiologic': [228, 984], 'studies': [229, 253, 311, 1221, 1260, 2178, 2909], 'such': [230, 2561, 2664], 'current': [233, 1456], 'have': [235, 305, 771, 825, 901, 1179], 'been': [237, 902, 2464], 'able': [238, 369], 'show': [240, 371, 512, 1157, 2586], 'disease,': [251, 1290, 1441, 1676, 2339, 3620, 3805, 3927, 4010, 4038], 'other': [252, 460, 522, 651, 701, 848, 1085, 2549, 2596, 2659, 2908], 'using': [254, 736, 2680], 'multivariate': [255, 432, 606, 667], 'analyses3456': [256], 'came': [257], 'opposite': [260, 1104], 'conclusion.': [261], 'Another': [262, 583], 'recently': [263, 3798], 'completed': [264], 'study,': [265, 968, 997, 2353, 3030, 3136], 'Worksite,7': [267], 'also': [268, 449, 507, 1400, 2323, 2425, 2581], 'found': [269, 1009, 2211, 2260, 3799], 'mortality,': [282, 388, 1325], 'especially': [283, 574, 1326], 'women.': [285], 'One': [286], 'might': [287, 390, 662, 1141], 'look': [288], 'subtle': [290], 'explanations': [291], 'account': [293, 675, 1118], 'differences': [296], 'various': [299], 'studies,': [300, 987], 'Culleton': [302, 854, 942, 1463], 'et': [303, 855, 943, 2258, 2299], 'al1': [304], 'attempted,': [306], 'most': [308], 'examined': [312, 810], 'very': [314, 509, 2583, 2600], 'same': [315, 2392], 'variables.A': [316], 'more': [317, 822, 951, 956, 1381, 1502, 2251, 2799, 2843], 'central': [318, 2100, 3443], 'issue': [319, 673, 2101, 2139], 'whether': [321, 1058, 1272, 1282, 2104, 2112, 2365], 'interpret': [324], 'finding': [326], 'statistically': [333], 'mean': [336], 'considered': [342, 972, 2785, 2806], 'biologically': [343], 'important.': [344], 'We': [345, 2672, 2769], 'would': [346, 715, 778, 914, 1244, 2571, 2638], 'argue': [347, 1245], 'several': [354, 2058, 2159, 2177], 'situations.': [355], 'First,': [356, 2195], 'if': [357, 395, 446, 518, 618, 765, 1017, 1034, 1359, 2328, 2592, 2912], 'factors': [360, 462, 524, 550, 1495, 2598, 2628, 2679, 2704], 'are': [361, 374, 559, 568, 706, 877, 891, 1267, 1337, 2235, 2243, 2616], 'causally': [362, 457], 'linked,': [363], 'then': [364], 'may': [366, 421, 443, 506, 770, 1170, 1177, 1197, 1199, 1403, 2489, 2503, 2580], 'they': [373, 558, 576, 900, 1061, 3895], 'each': [377], 'other.': [378], 'For': [379, 527], 'example,': [380, 528], 'although': [381], 'smoking': [382, 1176], 'no': [391, 2261, 2280, 2397, 2558, 2895], 'longer': [392, 2398], 'controlled': [398, 1220, 2013], 'chronic': [400, 803, 826, 1976, 2001], 'lung': [401, 404, 1190, 2716], 'cancer;': [405], 'major': [406, 860, 2750], 'causes': [407], 'death': [409], 'smokers.': [411], 'Similarly,': [412, 2412, 2907], 'impact': [414, 2641], 'hypertension': [416, 487, 932, 1099, 1208, 2845, 2876], 'decreased': [423, 445], 'when': [424, 648, 844, 2403, 2718], 'left': [425], 'ventricular': [426], 'hypertrophy': [427], 'included': [429, 450, 658, 2426], 'model;': [433], 'importance': [436, 1134, 3959], 'obesity': [438, 590], 'hyperinsulinemia': [447, 649], 'model.': [453], 'Whether': [454, 704], 'hyperuricemia': [455, 470, 598, 611, 713, 776, 801, 1018, 1109, 1672, 2967, 3017, 3162, 3266], 'linked': [458], 'remains': [463, 1256], 'unclear.': [464, 721], 'However,': [465, 630, 722, 889, 1167, 1212, 2098], 'observation': [467], 'longstanding': [469], 'patients': [472, 711, 773, 817, 1223, 1236, 2004, 3170, 3232, 3273], 'gout': [474, 819, 1225, 2002, 3639], 'associated': [476, 1123, 1317, 1419, 2108, 2723], 'intrarenal': [478], 'crystal': [479], 'deposition,': [480], 'tubulointerstitial': [481, 2451], 'injury': [482, 2452], 'development': [485, 1449, 2121, 2347, 2496], 'provides': [488], 'potential': [490, 2047, 2964], 'pathogenic': [491, 1286, 1969], 'mechanism': [492], 'linking': [493], 'elevated': [495, 593, 636, 693, 1313, 1333], 'renal': [499, 1210, 1233, 1242, 1678, 2006, 3802, 4009], '(even': [501], 'subclinical': [502], 'injury)': [503], 'hypertension.8It': [505], 'difficult': [510, 2584, 2634], 'linkage': [520, 2594], 'strong.': [526], 'Seven': [531, 1742], 'Countries': [532, 1743], 'Study,': [533, 3332], 'dietary': [534, 1762], 'intakes': [535], 'saturated': [537, 1727], 'fat,': [538], 'trans-fatty': [539], 'acids,': [540], 'cholesterol': [542, 1733, 1768], 'separated': [546], '"independent"': [548, 2185], '25-year': [552, 1735], 'coronary': [553, 645, 1592, 1738, 1788, 1824, 1868, 2540, 2543, 4036], 'heart': [554, 1527, 1593, 1739, 1789, 1869, 3117, 3166, 3700, 4037], 'because': [557, 2515], 'so': [560], 'highly': [561], 'interrelated.9': [562], 'Nevertheless,': [563], 'all': [564, 1008, 1428], 'fats': [567, 1764], 'believed': [569, 1435, 2332], 'pathophysiologically': [572], 'important,': [573], 'relate': [577], 'producing': [579], 'adverse': [580], 'lipoprotein': [581, 1767], 'patterns.1011': [582], 'example': [584], 'remarkable': [587], 'association': [588, 1379, 2199, 2262], 'insulin': [595, 2610], 'levels,': [596], '(the': [599], 'metabolic': [600, 655, 3435], 'syndrome': [601, 603, 656, 1805], '"X").12': [604], 'A': [605, 2129, 3027, 3401, 3931], 'model': [607, 2694], 'well': [609, 2617], 'eliminate': [610], 'even': [617, 647, 843, 1281], 'were': [620, 657, 821, 950, 970, 2361, 2410, 2804, 2832], 'contributing': [621], 'overall': [624, 1549], 'phenotypic': [625], 'syndrome.': [629], 'our': [631, 1055, 1069, 2352, 2762, 2818, 2888], 'recent': [632, 727, 1217, 2130], 'angiographic': [633], 'showed': [635], 'predictor': [643], 'atherosclerosis,': [646], 'markers': [652], 'model.13One': [661], 'make': [663], 'counterargument': [665], 'analyses': [668, 2893], 'does': [669, 2560, 2669, 2712, 2858], 'take': [670], 'latter': [672], 'into': [674], 'will': [677, 2157], 'provide': [678], 'measure': [680], 'effect': [683, 928, 939, 1181, 2862, 2872], 'just': [685], 'having': [686], 'particular': [688, 1339], '(such': [691], 'acid)': [695], 'absence': [698], 'factors.': [703], 'there': [705], 'really': [707], 'adequate': [708], 'numbers': [709], 'fit': [716], 'category': [719], 'concern': [724], 'analysis1': [729], 'was': [734, 871, 940, 1015, 1032, 2396, 2764], 'performed': [735], 'only': [737, 1421], 'single': [739], 'baseline': [740, 2360, 2385, 2409], 'level.': [743], 'Since': [744], 'acute': [745, 1849, 3699], 'changes': [746], '(of': [750], '1': [751, 1462], 'mg/mL': [752], 'more)': [754], 'can': [755, 1117, 1231, 2525], 'induced': [757], 'by': [758, 853, 884, 1040, 2149, 2166, 2256, 2294, 2487, 2557], 'alcohol,': [759], 'diet,': [760], 'exercise,14': [762], 'wonders': [764], 'involved': [772], 'transient': [775, 800], 'who': [777], 'presumably': [779], 'carry': [780], 'less': [781, 2244], 'developing': [784, 838], 'events.': [786], 'possible': [791, 2457], 'present': [794], 'separate': [797], 'individuals': [798, 1330, 2354, 2656], 'hyperuricemia,': [804, 2792, 3961], 'earlier': [806], '(who': [820], 'likely': [823, 952, 1382, 2236], 'hyperuricemia).': [827], 'This': [828, 1043, 2524], 'did': [830], 'significant': [833], 'males': [842], 'factored': [845], 'numerous': [847, 2061], 'factors.15In': [850], 'paper': [852], 'al,1': [856], 'eliminated': [863, 2753], 'use': [873, 1352, 1912, 2766, 2867], 'diuretics,': [875], 'which': [876, 899, 1075, 2687], 'known': [878, 2382, 2729], 'increase': [880, 910, 1054], 'reducing': [885, 1183], 'excretion.16': [888], 'diuretics': [890, 925, 949, 969, 1014, 1028, 1050, 2803], 'used': [892], 'treatment': [895, 1266, 1973, 2240, 2841, 3230, 3526], 'shown': [903], 'reduce': [905], 'it.16': [911], 'Therefore,': [912], 'expect': [916], 'see': [918, 2859], 'any': [919, 2308, 2835], 'effects': [921, 1264, 3521], 'controlling': [923, 2864], 'over': [926, 1074, 1129, 2868], 'out': [931, 2875], 'on': [933, 1029, 1095, 1765, 1844, 2250, 2466, 2649, 2698, 3531, 3924, 4013], 'yet': [937], 'observed.': [941], 'al': [944], 'suggested': [945], 'perhaps': [947, 2552], 'administered': [953], 'severe': [957, 2800, 2844], 'cases': [958], 'during': [962, 2533, 2542, 2810], 'time': [964, 2812, 2831], 'period': [965], 'generally': [971, 2201, 2805], 'first': [973, 2807], 'line': [974, 1293, 2808], 'therapy.16': [975], 'In': [976, 1020, 1084, 2289, 2351, 2376, 2390, 2788], 'regard,': [978], 'important': [981, 1154, 1309, 2492, 2775], 'both': [983, 1342], 'clinical': [986, 1884], 'Hypertension': [990, 1001, 1623, 1921, 2022, 2420, 3326, 3861, 4040], 'Detection': [991, 1624, 2275], 'Follow-up': [993, 1626], 'Program,': [994], 'Worksite': [996, 2209, 2388], 'Systolic': [1000, 1920, 2419], 'Elderly': [1004, 1924, 2423], 'program': [1005], '(SHEP)': [1006], 'trial': [1007], 'benefit': [1012, 1026, 1349], 'blunted': [1016], 'developed.6817': [1019], 'SHEP': [1022], 'trial,': [1023], 'entire': [1025], 'prevented': [1033], 'increased': [1039, 1319, 2508], '>1': [1041], 'mg/dL.17': [1042], 'suggests': [1044], 'per': [1051], 'se': [1052], 'result': [1062], 'hyperuricemia.': [1064, 1101, 2024], 'Perhaps': [1065], 'we': [1066, 1087, 2156, 2883], 'reverse': [1068], 'thinking': [1070], 'about': [1071], 'conclusions': [1073], 'viewed': [1079], 'dependent': [1081, 1094], 'independent.': [1083], 'words,': [1086], 'view': [1089], 'diuretic-associated': [1090], 'its': [1096, 1908], 'associations': [1097, 2603], 'Then': [1102], 'conclusion': [1105], 'made:': [1108], 'cause': [1113, 1439, 2336, 2568], 'excess': [1121], 'use.Given': [1126], 'concerns': [1128], 'factor,': [1139, 1279], 'posit': [1142], 'best': [1145], 'way': [1146], 'prove': [1148], 'pathogenically': [1153], 'blocking': [1159], 'treating': [1161], 'reduces': [1164], 'risk.': [1166], 'timing': [1169], 'critical.': [1172], 'Just': [1173], 'quitting': [1175], 'much': [1180], 'once': [1185, 1203], 'patient': [1187, 1205], 'has': [1188, 1206, 1284, 2053, 2089, 2307, 2463], 'developed': [1189], 'cancer,': [1191], 'lowering': [1193, 1228], 'helpful': [1202], 'established': [1207, 2702], 'injury.': [1211], 'exciting': [1215], 'prospective': [1218, 3028], 'suggest': [1226], 'improve': [1232], 'function': [1234, 2007], 'either': [1238], 'minimal': [1239], 'moderate': [1241], 'disease.1819We': [1243], 'role': [1248, 1287, 2118, 2310, 2436, 2468, 2493, 3610], 'unresolved': [1257], 'future': [1259], 'examining': [1261], 'pathogenesis': [1262, 1668, 3616, 3637], 'badly': [1268], 'needed.': [1269], 'Regardless': [1270], 'bottom': [1292], 'measuring': [1296], 'useful': [1301], 'test': [1302], 'clinician,': [1305], 'carries': [1308], 'prognostic': [1310], 'information.': [1311], 'An': [1312, 3794], 'women.1345678': [1328], 'Hypertensive': [1329], 'level': [1336], 'at': [1338, 2359, 2384, 2408, 2829], 'cerebrovascular': [1345], 'events,20': [1346], 'lower': [1354], 'blood': [1355], 'pressure': [1356], 'thwarted': [1358], 'remain': [1364], 'high': [1365], 'increase.6817': [1367], 'Table': [1368], '1.': [1369], 'Bradford': [1370, 2150, 2915], "Hill's": [1371, 2916], 'Criteria': [1372], 'Causation•Strength': [1374], 'association—the': [1376], 'stronger': [1377], 'relation': [1384, 2281, 2317, 2368], 'causal.•Dose-response': [1386], 'relation—as': [1387], 'dose': [1389], 'exposure': [1391, 1417, 1442, 2340], 'increases,': [1395], 'increases.': [1401], 'Exceptions': [1402], 'exist,': [1404], 'i.e.': [1405], 'threshold': [1407], 'effect.•Consistency—similar': [1408], 'different': [1411, 1414, 1759], 'studies;': [1412], 'populations.•Specificity—a': [1415], 'specific': [1416, 2325], '(possibly': [1424], 'weakest': [1426], 'criteria).•Temporal': [1430], 'relation—if': [1431], 'precede': [1447, 2345], 'disease.•Biological': [1452], 'plausibility—coherence': [1453], 'scientific': [1459], 'knowledge.': [1460], 'References': [1461], 'BF,': [1464], 'Larson': [1465], 'MG,': [1466], 'Kannel': [1467, 1862], 'WB,': [1468, 1863], 'Levy': [1469, 2037], 'D.': [1470], 'Serum': [1471, 1641, 1905, 3113, 3731, 3884, 4026], 'mortality:': [1480], 'Study.': [1484, 1744], 'Ann': [1485, 1505, 1978], 'Int': [1486, 1506, 1629], 'Med.1999;': [1487, 1507, 1773, 1794], '131:7–13.CrossrefMedlineGoogle': [1488], 'Scholar2': [1489], 'Vaccarino': [1490], 'V,': [1491, 3054, 3720], 'Krunholz': [1492], 'HM.': [1493], 'Risk': [1494, 3324], 'disease:': [1498, 1740, 1870, 3889, 3930], 'down,': [1500], 'many': [1501], 'evaluate.': [1504], '131:62–63.CrossrefMedlineGoogle': [1508], 'Scholar3': [1509], 'Freedman': [1510], 'DS,': [1511], 'Williamson': [1512], 'DF,': [1513], 'Gunter': [1514], 'EW,': [1515], 'Byers': [1516], 'T.': [1517], 'Relation': [1518], 'ischemic': [1526], 'disease.': [1528, 1679, 1790, 1826, 2350], 'Am': [1529, 1680, 1807, 1828, 1853], 'J': [1530, 1681, 1772, 1793, 1808, 1827, 1854, 1874, 2015, 3159, 3686, 3752], 'Epidemiol.1995;': [1531], '141:637–644.CrossrefMedlineGoogle': [1532], 'Scholar4': [1533], 'Bengtsson': [1534, 2257], 'C,': [1535, 1539, 2995, 3056, 3070, 3076, 3297, 3350, 3421, 3423], 'Lapidus': [1536], 'L,': [1537, 1721, 2940, 2953, 3068, 3074, 3216, 3718, 3778, 3988], 'Stendahl': [1538], 'Waldenstrom': [1540], 'Hyperuricemia': [1542, 2531, 3322, 3372, 3658, 3821], 'death:': [1550], '12-year': [1552], 'follow–up': [1553], 'participants': [1555], 'population': [1558], 'women': [1561], 'Gothenburg,': [1563], 'Sweden.': [1564], 'Acta': [1565], 'Med': [1566], 'Scand.1988;': [1567], '224:549–555.MedlineGoogle': [1568], 'Scholar5': [1569], 'Persky': [1570], 'VW,': [1571], 'Dyer': [1572], 'AR,': [1573], 'Idris-Soven': [1574], 'E,': [1575, 1992, 3052, 3511, 3877, 4052], 'Stamler': [1576], 'J,': [1577, 1715, 1996, 2991, 2999, 3250, 3254, 3311, 3501, 3505, 3680, 3875, 3946, 3984, 4054], 'Shekelle': [1578], 'RB,': [1579], 'Schoenburger': [1580], 'JA,': [1581], 'Berkson': [1582], 'DM,': [1583], 'Lindberg': [1584], 'HA.': [1585], 'acid:': [1587, 3793], 'disease?': [1594], 'Circulation.1979;': [1595], '59:969–977.CrossrefMedlineGoogle': [1596], 'Scholar6': [1597], 'Langford': [1598, 2298], 'HA,': [1599], 'Blaufox': [1600], 'MD,': [1601, 2034], 'Borhani': [1602], 'NO,': [1603], 'Curb': [1604], 'JD,': [1605], 'Molteni': [1606], 'A,': [1607, 1693, 1705, 1711, 1777, 1949, 1953, 1990, 2934, 2955, 3048, 3060, 3082, 3084, 3100, 3208, 3214, 3301, 3352, 3554, 3556, 3562, 3651, 3784], 'Schneider': [1608], 'KA,': [1609], 'Pressel': [1610], 'S.': [1611, 1640], 'Is': [1612], 'thiazide-produced': [1613], 'elevation': [1616], 'harmful?': [1617], 'data': [1620], 'Program.': [1627], 'Arch': [1628], 'Med.1987;': [1630], '147:645–649.CrossrefMedlineGoogle': [1631], 'Scholar7': [1632], 'Alderman': [1633], 'MH,': [1634], 'Cohen': [1635, 3517], 'H,': [1636, 1695, 2950, 3154, 3258, 3550, 3645, 3992], 'Madhavean': [1637], 'S,': [1638, 1662, 1703, 1713, 1719, 2930, 2938, 3005, 3050, 3558, 3560, 3843, 3982], 'Kivlighn': [1639, 1657], 'successfully': [1648], 'treated': [1649], 'hypertensive': [1650], 'patients.': [1651], 'Hypertension.1999;': [1652], '34:144–150.CrossrefMedlineGoogle': [1653], 'Scholar8': [1654], 'RJ,': [1656], 'SD,': [1658], 'Kim': [1659], 'Y-G,': [1660], 'Suga': [1661], 'Fogo': [1663], 'A.': [1664, 1998, 2021], 'Reappraisal': [1665], 'consequences': [1670], 'Kid': [1682], 'Dis.1999;': [1683], '33:225–234.CrossrefMedlineGoogle': [1684], 'Scholar9': [1685], 'Daan': [1686], 'K,': [1687, 2932, 3295, 3344, 3564, 3839], 'Allesandro': [1688], 'M,': [1689, 1707, 1709, 1717, 1894, 1896, 1951, 1986, 2936, 2944, 3044, 3046, 3058, 3062, 3094, 3106, 3212, 3218, 3289, 3309, 3342, 3364, 3386, 3413, 3419, 3425, 3552, 3596, 3598, 3647, 3649, 3684, 4050], 'Bloemberg': [1690], 'B,': [1691, 1723, 3600, 3682], 'Christ': [1692], 'Blackburn': [1694], 'Buzina': [1696], 'R,': [1697, 2928, 3092, 3291, 3458, 3990], 'Dontas': [1698], 'AS,': [1699], 'Fidanza': [1700], 'F,': [1701, 1947, 1984, 3072, 3080, 3104], 'Giampaoli': [1702], 'Jansen': [1704], 'Karvonen': [1706], 'Katan': [1708, 1778], 'Nissinen': [1710], 'Nedeljkovic': [1712], 'Pekkanen': [1714], 'Pakkarinen': [1716], 'Punsar': [1718], 'Räsänen': [1720], 'Simic': [1722], 'Toshima': [1724], 'H.': [1725], 'Dietary': [1726], 'trans': [1729], 'fatty': [1730, 1785], 'acids': [1731, 1786], 'Prev': [1745], 'Med.1995;': [1746], '24:308–315.CrossrefMedlineGoogle': [1747], 'Scholar10': [1748], 'Lichtenstein': [1749], 'AH,': [1750], 'Ausman': [1751], 'LM,': [1752], 'Jalbert': [1753], 'SM,': [1754], 'Schaefer': [1755], 'EJ.': [1756], 'Effects': [1757, 1838, 2231], 'forms': [1760], 'hydrogenated': [1763], 'levels.': [1769], 'N': [1770, 1791, 3156, 3263, 3722, 3845], 'Engl': [1771, 1792], '340:1930–1940.CrossrefMedlineGoogle': [1774], 'Scholar11': [1775], 'Ascherioa': [1776], 'MB,': [1779], 'Stampfer': [1780], 'MJ,': [1781, 1835, 1988], 'Willett': [1782], 'WC.': [1783], 'Trans': [1784], '340:1994–1998.CrossrefMedlineGoogle': [1795], 'Scholar12': [1796], 'Reaven': [1797], 'GM.': [1798], 'kidney:': [1800], 'unwilling': [1802], 'accomplice': [1803], 'X.': [1806], 'Kidney': [1809, 3196, 3493, 3806], 'Dis.1997;': [1810], '30:928–931.CrossrefMedlineGoogle': [1811], 'Scholar13': [1812], 'KR,': [1814], 'Short': [1815, 3910], 'RA,': [1816], 'RJ.': [1818], 'Relationship': [1819, 3468], 'between': [1820, 2282, 2318, 2369], 'artery': [1825, 2544], 'Soc': [1829], 'Nephrol.1999;': [1830], '10:373A.': [1831], 'Abstract.Google': [1832], 'Scholar14': [1833], 'Maclachlan': [1834], 'Rodnan': [1836], 'GP.': [1837], 'food,': [1840], 'fast': [1841], 'alcohol': [1843, 2614], 'attacks': [1850], 'gout.': [1852, 1977], 'Med.1967;': [1855], '42:38–57.CrossrefMedlineGoogle': [1856], 'Scholar15': [1857], 'Abbott': [1858], 'RD,': [1859], 'Brand': [1860], 'FN,': [1861], 'Castelli': [1864], 'WP.': [1865], 'Gout': [1866, 3978], 'study.': [1873, 2014], 'Clin': [1875, 2016], 'Epidemiol.1988;': [1876], '41:237–242.CrossrefMedlineGoogle': [1877], 'Scholar16': [1878], 'Papademetriou': [1879], 'V.': [1880], 'Diuretics': [1881], 'hypertension:': [1883], 'experiences.': [1885], 'Eur': [1886], 'J.1992;': [1888], '13:S92–S95.CrossrefMedlineGoogle': [1889], 'Scholar17': [1890], 'Franse': [1891], 'LV,': [1892], 'Pahor': [1893], 'DiBari': [1895], 'Shorr': [1897], 'RI,': [1898], 'Wan': [1899], 'JY,': [1900], 'Somes': [1901], 'GW,': [1902], 'Applegate': [1903], 'WB.': [1904], 'acid,': [1907, 3115], 'change': [1909], 'Program': [1925], '(SHEP).': [1926], 'Abstract': [1927], 'presented': [1928], 'at:': [1929], 'Fourteenth': [1930], 'Scientific': [1931], 'Meeting': [1932], 'American': [1935, 3406, 3899], 'Society': [1936], 'Hypertension;': [1938], 'May': [1939], '16-20,': [1940], '1999;': [1941], 'New': [1942, 3403], 'York,': [1943], 'NY.Google': [1944], 'Scholar18': [1945], 'Perez-Ruiz': [1946, 1983], 'Alonso-Ruiz': [1948, 1997], 'Calabozo': [1950, 1985], 'Herrero-Beites': [1952, 1989], 'Garcia-Erauskin': [1954], 'G,': [1955, 1994, 2948, 3066, 3078, 3090, 3096, 3098, 3150, 3252, 3307, 3362], 'Ruiz-Lucca': [1956], 'E.': [1957], 'Efficacy': [1958], 'allopurinol': [1960], 'benzbromarone': [1962], 'control': [1965, 2676], 'hyperuricemia:': [1967], 'approach': [1970], 'primary': [1975], 'Rheum': [1979], 'Dis.1998;': [1980], '57:545–549.CrossrefMedlineGoogle': [1981], 'Scholar19': [1982], 'Fernandez-Lopez': [1987], 'Ruiz-Lucea': [1991], 'Garcia-Erasukin': [1993], 'Duruelo': [1995], 'Treatment': [1999], 'impairment:': [2008], 'open,': [2010], 'randomized': [2011, 2239], 'actively': [2012], 'Rheumatol.1999;': [2017], '5:49–55.CrossrefMedlineGoogle': [2018], 'Scholar20': [2019], 'Breckenridge': [2020], 'Lancet.': [2025], '1966;': [2026], 'i:15–18.Google': [2027], 'ScholarhypertensionahaHypertensionHypertensionHypertension0194-911X1524-4563Lippincott': [2028], 'Williams': [2029], '&': [2030, 3964], 'WilkinsResponseCulleton': [2031], 'Bruce,': [2032], ',': [2033], 'FRCPC': [2035], 'Daniel,': [2038], 'MD032000The': [2039], 'interest': [2040], '(CVD)': [2050], 'ballooned': [2054], 'last': [2057], 'years': [2059], 'abstracts': [2062], 'research': [2064], 'papersR1R2R3R4R5R6R7R8R9': [2065], 'multiple': [2067], 'editorials': [2068], 'review': [2070], 'articles.R10R11R12R13R14R15': [2071], 'There': [2072], 'seems': [2073], 'little': [2074], 'doubt': [2075, 2303], 'CVD,': [2085, 2110, 2123], 'perception': [2087], 'persisted': [2090], 'varying': [2092], 'degrees': [2093], 'nearly': [2095], '50': [2096], 'years.R16': [2097], 'plays': [2115], 'causal': [2117, 2126, 2309, 2435, 2903], 'ie,': [2124], 'factor.': [2128, 2906], 'editorialR12': [2131], 'commended': [2135], 'considering': [2137], 'according': [2140], 'main': [2143], 'criteria': [2144, 2160, 2917], 'causation': [2146], 'described': [2148], 'Hill': [2151, 3310], '(Table).R17': [2152], 'To': [2153], 'avoid': [2154], 'repetition,': [2155], 'highlight': [2158], 'specifically': [2162], 'address': [2163], 'issues': [2164], 'raised': [2165], 'commentary.Johnson': [2173], 'claim': [2176, 2293, 2577], 'demonstrate': [2179], 'CVD.R1R18R19R20R21': [2189], 'Let': [2190], 'us': [2191], 'consider': [2192], 'evidence.': [2194], 'strength': [2197], 'weak': [2202], 'nonexistent': [2204], 'reports.': [2207], 'project': [2210], 'hazard': [2213], 'ratio': [2214], '1.22': [2216], 'CVD': [2218, 2286, 2322, 2358, 2374, 2383, 2402, 2407, 2441, 2631, 2650, 2660, 2730, 2904], 'incidence': [2219, 2651], 'top': [2222, 2923], 'quartile': [2223], 'versus': [2227, 3527], 'lowest': [2229], 'quartile.R1': [2230], 'size': [2234], 'meaningful': [2237], 'trials': [2241], 'convincing': [2245], 'observational': [2247], 'studies.': [2248], 'Furthermore,': [2249], 'analysis,': [2253, 2975], 'alR19': [2259], 'incident': [2267, 2401, 2454, 2630, 3164, 3268], 'CVD.': [2268], 'Data': [2269], 'Chicago': [2272, 2414], 'Association': [2274, 3728], 'Project': [2276], 'Industry': [2278], 'revealed': [2279, 2894], 'men.R20': [2288], 'contrast': [2290], 'Tuttle,': [2297], 'alR21': [2300], 'concluded,': [2301], '"we': [2302], 'increasing': [2312], 'mortality."Examination': [2313], 'temporal': [2316, 2367], 'warrants': [2324], 'comment.': [2326], 'Clearly,': [2327], 'clinically': [2356, 2528], 'apparent': [2357], 'excluded': [2362], 'determine': [2364], 'existed.R3': [2375], 'contrast,': [2377], '17%': [2378], 'subjects': [2380, 2404, 2427], 'had': [2381, 2842], 'report.R1': [2389], 'report,': [2393], 'predictive': [2399], 'prevalent': [2406, 2429], 'excluded.': [2411], 'AssociationR20': [2416], 'ProgramR7': [2424], 'CVD.The': [2430], 'biological': [2431], 'plausibility': [2432], 'inconclusive.': [2443], 'Intrarenal': [2444], 'deposition': [2445], 'subsequent': [2450], 'hypertensionR13': [2455], 'established.': [2460], 'Recently,': [2461], 'attention': [2462], 'focused': [2465], 'antioxidant.R22': [2474], 'Increased': [2475], 'oxidative': [2476, 2554], 'stress': [2477], 'oxidation': [2480], 'LDL': [2482], 'arterial': [2485, 2537], 'wall': [2486], 'peroxynitrite': [2488], 'play': [2490], 'atherosclerosis.': [2498], 'Elevated': [2499], 'reflect': [2504], 'response': [2506], 'production': [2509], 'endogenous': [2511], 'reactive': [2512], 'oxygen': [2513], 'species': [2514], 'potent': [2520], 'scavenger': [2521], 'peroxynitrite.R23': [2523], 'demonstrated': [2527], 'well.': [2530], 'occurs': [2532], 'interruption': [2534], 'limb': [2536], 'flow,R24': [2538], 'angioplasty,R25': [2541], 'bypass': [2545], 'surgery,R26': [2546], 'hypoxic': [2550], 'statesR27R28R29': [2551], 'reflecting': [2553], 'stress,': [2555], 'means': [2559, 4004], 'evidence': [2562, 2896, 3917], 'implicate': [2563], 'atherosclerosis.We': [2570], 'agree': [2572], "Tuttle's": [2576, 2855], '"it': [2579], 'strong."': [2601], 'dyslipidemia,': [2609], 'resistance,': [2611], 'obesity,': [2612], 'abuse': [2615], 'described.': [2618], 'Multicollinearity': [2619], 'statistical': [2621, 2682, 3932], 'models': [2622], 'exploring': [2623], 'relations': [2625], 'problem.': [2635], 'Ideally,': [2636], 'examine': [2639], 'range': [2644], 'values': [2648], 'cohort': [2654, 3029], 'homogeneous': [2657], 'factors;': [2662], 'however,': [2663], 'theoretical': [2666], 'sample': [2668], 'exist.': [2671], 'therefore': [2673], 'adjust,': [2674], 'for,': [2677], 'accepted': [2681], 'techniques.': [2683], 'choice': [2685], 'include': [2690], 'multivariable': [2693], 'based': [2696], 'largely': [2697], 'knowledge': [2700], 'outcome': [2707, 3694], 'interest.': [2709], 'Obviously,': [2710], 'adjust': [2714], 'cancer': [2717], 'determining': [2719], 'smoking!Even': [2725], 'adjusting': [2727], 'factors,': [2732], 'possibility': [2734], 'residual': [2736], 'confounding': [2737], 'considered.': [2740], 'As': [2741], 'highlighted': [2742], 'commentary,': [2746], 'reportR3': [2763], 'diuretics.': [2768], 'feel': [2770], 'therapy': [2772, 2794, 2809, 3530], 'confounder': [2776], 'acid–CVD': [2780], 'analyses.': [2787], 'addition': [2789], 'inducing': [2791], 'marker': [2797], 'hypertension.': [2801], 'Although': [2802], 'collection': [2816], 'investigation,': [2819], 'large': [2821, 3121], 'majority': [2822], 'hypertensives': [2824], 'United': [2827], 'States': [2828], 'receiving': [2834, 2839, 2849], 'drug': [2836], 'therapy.R30': [2837], 'Subjects': [2838], 'antihypertensive': [2840], 'than': [2846], 'those': [2847], 'therapy.R31': [2850], 'Contrary': [2851], 'claim,': [2856], 'above': [2870], 'alone': [2877], 'precisely': [2881], 'what': [2882], 'observed.In': [2884], 'conclusion,': [2885], 'results': [2886], 'extensive': [2889], 'carefully': [2891], 'conceived': [2892], 'support': [2898], 'meet': [2910], 'few,': [2911], 'any,': [2913], 'causation.': [2919], 'Previous': [2920], 'Back': [2921], 'Next': [2924], 'FiguresReferencesRelatedDetailsCited': [2925], 'By': [2926], 'Ehren': [2927], 'Habbig': [2929], 'Krupka': [2931], 'Ernst': [2933], 'Bald': [2935], 'König': [2937], 'Murer': [2939], 'Özçakar': [2941], 'Z,': [2942, 2985, 3716], 'Pohl': [2943], 'Babenko': [2945], 'N,': [2946, 3003], 'Spartà': [2947], 'Staude': [2949], 'Dello': [2951], 'Strologo': [2952], 'Szabó': [2954], 'Tönshoff': [2956], 'B': [2957, 3604], 'Weber': [2959], 'L': [2960, 3630, 3879, 3994], '(2022)': [2961], 'Prevalence': [2962], 'relevance': [2965], 'pediatric': [2969], 'kidney': [2970, 3929], 'transplant': [2971], 'recipients—a': [2972], 'CERTAIN': [2973], 'registry': [2974], 'Pediatric': [2976], 'Transplantation,': [2977, 3866], '10.1111/petr.14265,': [2978], '26:4,': [2979], 'Online': [2980, 3039, 3143, 3181, 3243, 3284, 3337, 3381, 3453, 3478, 3543, 3591, 3625, 3673, 3711, 3767, 3811, 3834, 3870, 3906, 3941, 3971, 4019, 4045, 4082], 'publication': [2981, 3040, 3144, 3182, 3244, 3285, 3338, 3382, 3454, 3479, 3544, 3592, 3626, 3674, 3712, 3768, 3812, 3835, 3871, 3907, 3942, 3972, 4020, 4046, 4083], 'date:': [2982, 3041, 3145, 3183, 3245, 3286, 3339, 3383, 3455, 3480, 3545, 3593, 3627, 3675, 3713, 3769, 3813, 3836, 3872, 3908, 3943, 3973, 4021, 4047, 4084], '1-Jun-2022.': [2983], 'Cheng': [2984, 3153, 3257], 'Zheng': [2986, 3004], 'T,': [2987, 3305, 3348, 3356, 3360, 3415, 3772, 3780, 3986], 'Zhang': [2988], 'D,': [2989, 3001, 3206, 3210, 3509, 3602, 3678, 3774, 3776, 3841], 'Yang': [2990], 'Hu': [2992], 'X,': [2993, 2997, 3148], 'Yin': [2994], 'Ren': [2996], 'Li': [2998, 3002], 'Shi': [3000], 'Wang': [3006, 3155, 3262], 'M': [3007, 3313, 3366, 3390, 3463, 3518, 3569, 3633, 3689, 3786, 3816, 3819, 3976], 'Bai': [3009], 'Y': [3010], '(2021)': [3011], 'High-level': [3012], 'asymptomatic': [3016], 'isolated': [3021], 'cardio-cerebrovascular': [3025], 'diseases:': [3026], 'Nutrition,': [3031, 3173, 3280], 'Metabolism': [3032, 3174, 3193, 3490], 'Diseases,': [3035, 3177, 3377, 3824], '10.1016/j.numecd.2021.08.043,': [3036], '31:12,': [3037], '(3415-3425),': [3038], '1-Nov-2021.': [3042], 'Muiesan': [3043], 'Salvetti': [3045], 'Virdis': [3047], 'Masi': [3049], 'Casiglia': [3051], 'Tikhonoff': [3053], 'Barbagallo': [3055], 'Bombelli': [3057], 'Cicero': [3059], 'Cirillo': [3061, 3063], 'P,': [3064, 3086, 3088, 3102, 3299, 3354, 3503], 'Desideri': [3065], "D'Eliak": [3067], 'Ferri': [3069], 'Galletti': [3071], 'Gesualdo': [3073], 'Giannattasio': [3075], 'Iaccarino': [3077], 'Mallamaci': [3079], 'Maloberti': [3081], 'Mazza': [3083], 'Nazzaro': [3085], 'Palatini': [3087], 'Parati': [3089], 'Pontremoli': [3091], 'Rattazzi': [3093], 'Rivasi': [3095], 'Tocci': [3097], 'Ungar': [3099], 'Verdecchia': [3101], 'Viazzi': [3103], 'Volpe': [3105], 'Grassi': [3107], 'G': [3108, 3656], 'Borghi': [3110, 3219], 'C': [3111, 3220, 3848], '(2020)': [3112, 3160, 3190], 'predicts': [3116], 'failure': [3118, 3167, 3701], 'Italian': [3122], 'cohort:': [3123], 'search': [3124], 'cut-off': [3127], 'value': [3128], 'URic': [3130], 'Right': [3132], 'heArt': [3134], 'Health': [3135], 'Journal': [3137, 3277, 3407, 3446, 3584, 3704, 3743, 3900, 4075], 'Hypertension,': [3139, 3378, 3409], '10.1097/HJH.0000000000002589,': [3140], '39:1,': [3141], '(62-69),': [3142], '1-Jan-2021.': [3146], 'Wu': [3147, 3158, 3249, 3259], 'Jian': [3149, 3251], 'Tang': [3151, 3255], 'Y,': [3152, 3204, 3256, 3303, 3358, 3388, 3417, 3548, 3782], 'Asymptomatic': [3161, 3265, 3371], 'congestive': [3165], 'elderly': [3169, 3271], 'without': [3171, 3274], 'comorbidities,': [3172, 3275], '10.1016/j.numecd.2019.12.008,': [3178], '30:4,': [3179], '(666-673),': [3180], '1-Apr-2020.': [3184], 'Kang': [3185, 3209, 3482, 3601, 3773], 'D': [3186, 3483], 'R': [3189, 3223, 3316, 3369, 3393, 3430, 3486, 3566, 3607, 3789, 3911, 3952, 3997, 4059], 'Chronic': [3197, 3494], 'Renal': [3198, 3495, 3757, 3863], 'Disease,': [3199, 3496, 3582, 3667, 3740, 3758], '10.1016/B978-0-12-815876-0.00043-7,': [3200], '(689-701),': [3201], '.': [3202, 3499, 3643, 3750], 'Sato': [3203, 3302, 3357, 3387], 'Feig': [3205, 3775], 'Stack': [3207], 'Lanaspa': [3211, 3312, 3365, 3424, 3462], 'Ejaz': [3213, 3783], 'Sánchez-Lozada': [3215], 'Kuwabara': [3217, 3288, 3290, 3341, 3385], '(2019)': [3224, 3264], 'case': [3226], 'acid-lowering': [3229], 'hyperuricaemia': [3234], 'CKD,': [3236], 'Nature': [3237], 'Reviews': [3238], 'Nephrology,': [3239, 3937], '10.1038/s41581-019-0174-z,': [3240], '15:12,': [3241], '(767-775),': [3242], '1-Dec-2019.': [3246], 'Tu': [3247], 'W,': [3248], 'Lori': [3253], 'X': [3260], 'stroke': [3269], 'Chinese': [3272], 'European': [3276, 3445, 3703], 'Clinical': [3279, 3916, 3966, 4077], '10.1038/s41430-019-0405-1,': [3281], '73:10,': [3282], '(1392-1402),': [3283], '1-Oct-2019.': [3287], 'Hisatome': [3292, 3345], 'I,': [3293, 3346, 3513], 'Niwa': [3294, 3343], 'Roncal-Jimenez': [3296, 3349, 3420], 'Bjornstad': [3298, 3353], 'Andres-Hernando': [3300, 3351], 'Jensen': [3304, 3355, 3414], 'Garcia': [3306, 3361], 'Ohno': [3308, 3363], '(2017)': [3317, 3370, 3394], '"Metabolically': [3318], 'Healthy"': [3319], 'Obesity': [3320, 3537], 'Increase': [3323], 'Diabetes:': [3328], '5-year': [3329], 'Japanese': [3330], 'Cohort': [3331], 'Obesity,': [3333], '10.1002/oby.22000,': [3334], '25:11,': [3335], '(1997-2008),': [3336], '1-Nov-2017.': [3340], 'Nakagawa': [3347, 3426, 3771, 3985], 'Milagres': [3359], 'Without': [3373], 'Comorbidities': [3374], 'Predicts': [3375], 'Cardiometabolic': [3376], '69:6,': [3379], '(1036-1044),': [3380], '1-Jun-2017.': [3384], 'Kanbay': [3389, 3412, 3568, 3595], 'Left': [3398], 'Ventricular': [3399], 'Hypertrophy:': [3400], 'Potentially': [3402], 'Modifiable': [3404], 'Target?,': [3405], '10.1093/ajh/hpw195,': [3410], '(hpw195)': [3411], 'Solak': [3416, 3547], 'Le': [3418], 'Rivard': [3422], 'T': [3427, 3460], '(2016)': [3431], 'syndrome:': [3436], 'From': [3437], 'innocent': [3439], 'bystander': [3440], 'player,': [3444], 'Internal': [3448], 'Medicine,': [3449, 3587, 3669, 3746, 3902], '10.1016/j.ejim.2015.11.026,': [3450], '29,': [3451], '(3-8),': [3452], '1-Apr-2016.': [3456], 'Merriman': [3459], '(2015)': [3464, 3487], 'Causal': [3465], 'Noncausal': [3467], 'With': [3472], 'Diabetes,': [3473, 3474, 3536], '10.2337/db15-0532,': [3475], '64:8,': [3476], '(2720-2722),': [3477], '1-Aug-2015.': [3481], '10.1016/B978-0-12-411602-3.00035-4,': [3497], '(418-428),': [3498], 'Dziuba': [3500], 'Alperin': [3502], 'Racketa': [3504], 'Iloeje': [3506], 'U,': [3507], 'Goswami': [3508], 'Hardy': [3510], 'Perlstein': [3512], 'Grossman': [3514], 'H': [3515, 3882], '(2014)': [3519, 3570], 'Modeling': [3520], 'SGLT-2': [3523], 'inhibitor': [3524], 'dapagliflozin': [3525], 'standard': [3528], 'diabetes': [3529], 'microvascular': [3534], 'outcomes,': [3535], 'Metabolism,': [3539], '10.1111/dom.12261,': [3540], '16:7,': [3541], '(628-635),': [3542], '1-Jul-2014.': [3546], 'Akilli': [3549], 'Kayrak': [3551], 'Aribas': [3553], 'Gaipov': [3555], 'Turk': [3557], 'Perez-Pozo': [3559], 'Covic': [3561], 'McFann': [3563], 'Level': [3573], 'Erectile': [3575], 'Dysfunction': [3576, 3859], 'Patients': [3578], 'Coronary': [3580, 3665, 3738], 'Artery': [3581, 3666, 3739], 'Sexual': [3586], '10.1111/jsm.12332,': [3588], '11:1,': [3589], '(165-172),': [3590], '1-Jan-2014.': [3594], 'Segal': [3597, 3785], 'Afsar': [3599], 'Rodriguez-Iturbe': [3603], '(2013)': [3608], 'human': [3618, 4072], 'Heart,': [3621], '10.1136/heartjnl-2012-302535,': [3622], '99:11,': [3623], '(759-766),': [3624], '1-Jun-2013.': [3628], 'McLean': [3629], 'Becker': [3632, 3815], '(2011)': [3634], 'Etiology': [3635], 'Rheumatology,': [3640, 3967], '10.1016/B978-0-323-06551-1.00183-4,': [3641], '(1841-1857.e3),': [3642], 'Goodarzynejad': [3644], 'Anvari': [3646], 'Boroumand': [3648], 'Karimi': [3650], 'Abbasi': [3652], 'S': [3653, 3725, 4024], 'Davoodi': [3655], '(2010)': [3657], 'Presence': [3661], 'Severity': [3663], 'Laboratory': [3668], '10.1309/LMKDB9PBKZGUS20T,': [3670], '41:1,': [3671], '(40-45),': [3672], '1-Jan-2010.': [3676], 'Pascual-Figal': [3677], 'Hurtado-Martínez': [3679], 'Redondo': [3681], 'Antolinos': [3683], 'Ruiperez': [3685], 'Valdes': [3688], '(2007)': [3690, 3726], 'Hyperuricaemia': [3691], 'long-term': [3693], 'hospital': [3696], 'discharge': [3697], 'patients,': [3702], 'Failure,': [3707], '10.1016/j.ejheart.2006.09.001,': [3708], '9:5,': [3709], '(518-524),': [3710], '1-May-2007.': [3714], 'Jelic-Ivanovic': [3715], 'Memon': [3717], 'Spasojevic-Kalimanovska': [3719], 'Bogavac-Stanojevic': [3721], 'Spasic': [3724], 'Independent': [3727], 'High': [3730], 'Concentration': [3734], 'Angiographically': [3736], 'Defined': [3737], 'Tohoku': [3742], 'Experimental': [3745], '10.1620/tjem.211.369,': [3747], '211:4,': [3748], '(369-377),': [3749], 'Cameron': [3751], '(2006)': [3753, 3790, 3820], 'Nucleosides,': [3759], 'Nucleotides': [3760], 'Nucleic': [3762], 'Acids,': [3763], '10.1080/15257770600890954,': [3764], '25:9-11,': [3765], '(1055-1064),': [3766], '1-Jun-2006.': [3770], 'Sanchez-Lozada': [3777], 'Srinivas': [3779], 'Sautin': [3781], 'Unearthing': [3791], 'ancient': [3795], 'significance': [3800], 'International,': [3807], '10.1038/sj.ki.5000391,': [3808], '69:10,': [3809], '(1722-1725),': [3810], '1-May-2006.': [3814, 3837], 'Jolly': [3818], 'Associated': [3823], 'Rheumatic': [3825], 'Clinics': [3827], 'North': [3829], 'America,': [3830], '10.1016/j.rdc.2006.02.005,': [3831], '32:2,': [3832], '(275-293),': [3833], 'Armstrong': [3838], 'Campbell': [3842], 'Isbel': [3844], 'Hawley': [3847], '(2005)': [3849, 3883, 3915, 3998], 'Does': [3850], 'Have': [3853], 'Pathogenetic': [3855], 'Graft': [3858], 'Transplant': [3864], 'Recipients?,': [3865], '10.1097/01.tp.0000183895.88572.13,': [3867], '80:11,': [3868], '(1565-1571),': [3869], '1-Dec-2005.': [3873], 'Baker': [3874], 'Krishnan': [3876], 'Chen': [3878], 'Schumacher': [3881], 'Recent': [3890], 'developments,': [3891], 'where': [3893], 'do': [3894], 'leave': [3896], 'us?,': [3897], '10.1016/j.amjmed.2005.03.043,': [3903], '118:8,': [3904], '(816-826),': [3905], '1-Aug-2005.': [3909], 'K': [3914], 'influence': [3920], 'modeling': [3933], 'perspective,': [3934], 'Seminars': [3935], '10.1016/j.semnephrol.2004.09.005,': [3938], '25:1,': [3939], '(25-31),': [3940], '1-Jan-2005.': [3944], 'Vázquez-Mellado': [3945], 'Alvarez': [3947], 'Hernández': [3948], 'E': [3949], 'Burgos-Vargas': [3951], '(2004)': [3953], 'Primary': [3954], 'prevention': [3955], 'rheumatology:': [3957], 'Best': [3962], 'Practice': [3963], 'Research': [3965], '10.1016/j.berh.2004.01.001,': [3968], '18:2,': [3969], '(111-124),': [3970], '1-Apr-2004.': [3974], 'Snaith': [3975], '(2003)': [3977], 'eLS,': [3979], '10.1038/npg.els.0002311': [3980], 'Watanabe': [3981], 'Kanellis': [3983], 'Han': [3987], 'Ohashi': [3989], 'Lan': [3991], 'Feng': [3993], 'Reducing': [3999], 'prevent': [4006], 'Expert': [4011], 'Opinion': [4012], 'Therapeutic': [4014], 'Patents,': [4015], '10.1517/13543776.12.2.193,': [4016], '12:2,': [4017], '(193-199),': [4018], '1-Feb-2002.': [4022], 'Wannamethee': [4023], '(2001)': [4025, 4060], 'Current': [4039], 'Reports,': [4041], '10.1007/s11906-001-0037-3,': [4042], '3:3,': [4043], '(190-196),': [4044], '1-Jun-2001.': [4048], 'Lipkowitz': [4049], 'Leal-Pinto': [4051], 'Rappoport': [4053], 'Najfeld': [4055], 'V': [4056], 'Abramson': [4058], 'Functional': [4061], 'reconstitution,': [4062], 'membrane': [4063], 'targeting,': [4064], 'genomic': [4065], 'structure,': [4066], 'chromosomal': [4068], 'localization': [4069], 'urate': [4073], 'transporter,': [4074], 'Investigation,': [4078], '10.1172/JCI12471,': [4079], '107:9,': [4080], '(1103-1115),': [4081], '1-May-2001.': [4085], 'March': [4086], '2000Vol': [4087], 'Issue': [4089], '3': [4090], 'Advertisement': [4091, 4101], 'Article': [4092], 'InformationMetrics': [4093], 'https://doi.org/10.1161/01.HYP.35.3.e10': [4094], 'publishedMarch': [4096], '1,': [4097], '2000': [4098], 'PDF': [4099], 'download': [4100]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2170197815', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}], 'updated_date': '2024-12-20T20:06:39.808580', 'created_date': '2016-06-24'}