Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2168847156', 'doi': 'https://doi.org/10.1093/humrep/deg260', 'title': 'Testicular sperm extraction (TESE) and ICSI in patients with permanent azoospermia after chemotherapy', 'display_name': 'Testicular sperm extraction (TESE) and ICSI in patients with permanent azoospermia after chemotherapy', 'publication_year': 2003, 'publication_date': '2003-04-29', 'ids': {'openalex': 'https://openalex.org/W2168847156', 'doi': 'https://doi.org/10.1093/humrep/deg260', 'mag': '2168847156', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12773459'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/humrep/deg260', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S127900037', 'display_name': 'Human Reproduction', 'issn_l': '0268-1161', 'issn': ['0268-1161', '1460-2350'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027604970', 'display_name': 'Marcos Meseguer', 'orcid': 'https://orcid.org/0000-0002-0438-8589'}, 'institutions': [{'id': 'https://openalex.org/I2802601399', 'display_name': 'Guardia Civil', 'ror': 'https://ror.org/02w3h2896', 'country_code': 'ES', 'type': 'government', 'lineage': ['https://openalex.org/I2802601399']}], 'countries': ['ES'], 'is_corresponding': True, 'raw_author_name': 'M. Meseguer', 'raw_affiliation_strings': ['Andrology Laboratory and Semen Bank, Instituto Valenciano de Infertilidad, Spain.'], 'affiliations': [{'raw_affiliation_string': 'Andrology Laboratory and Semen Bank, Instituto Valenciano de Infertilidad, Spain.', 'institution_ids': ['https://openalex.org/I2802601399']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5027604970'], 'corresponding_institution_ids': ['https://openalex.org/I2802601399'], 'apc_list': {'value': 3752, 'currency': 'EUR', 'value_usd': 4046, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 7.827, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 172, 'citation_normalized_percentile': {'value': 0.960202, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '18', 'issue': '6', 'first_page': '1281', 'last_page': '1285'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10116', 'display_name': 'Sperm and Testicular Function', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10116', 'display_name': 'Sperm and Testicular Function', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11069', 'display_name': 'Testicular diseases and treatments', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10364', 'display_name': 'Reproductive Biology and Fertility', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/testicular-sperm-extraction', 'display_name': 'Testicular sperm extraction', 'score': 0.8657165}, {'id': 'https://openalex.org/keywords/sperm-retrieval', 'display_name': 'Sperm Retrieval', 'score': 0.6112168}, {'id': 'https://openalex.org/keywords/sperm-bank', 'display_name': 'Sperm bank', 'score': 0.5282161}], 'concepts': [{'id': 'https://openalex.org/C2777420699', 'wikidata': 'https://www.wikidata.org/wiki/Q794026', 'display_name': 'Azoospermia', 'level': 4, 'score': 0.9228177}, {'id': 'https://openalex.org/C35035537', 'wikidata': 'https://www.wikidata.org/wiki/Q3733593', 'display_name': 'Testicular sperm extraction', 'level': 5, 'score': 0.8657165}, {'id': 'https://openalex.org/C2778278907', 'wikidata': 'https://www.wikidata.org/wiki/Q28700', 'display_name': 'Intracytoplasmic sperm injection', 'level': 4, 'score': 0.7191506}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.65203154}, {'id': 'https://openalex.org/C2910159267', 'wikidata': 'https://www.wikidata.org/wiki/Q7449214', 'display_name': 'Sperm Retrieval', 'level': 5, 'score': 0.6112168}, {'id': 'https://openalex.org/C81877008', 'wikidata': 'https://www.wikidata.org/wiki/Q1049937', 'display_name': 'Sperm bank', 'level': 4, 'score': 0.5282161}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.504707}, {'id': 'https://openalex.org/C2776212926', 'wikidata': 'https://www.wikidata.org/wiki/Q324464', 'display_name': 'Testicular cancer', 'level': 3, 'score': 0.49325937}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.37907395}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.3197913}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.30557936}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.28883994}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14613014}, {'id': 'https://openalex.org/C518429986', 'wikidata': 'https://www.wikidata.org/wiki/Q964401', 'display_name': 'Fertility', 'level': 3, 'score': 0.099627495}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.045523763}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D009845', 'descriptor_name': 'Oligospermia', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D020554', 'descriptor_name': 'Sperm Injections, Intracytoplasmic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013737', 'descriptor_name': 'Testis', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D020858', 'descriptor_name': 'Tissue and Organ Harvesting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015925', 'descriptor_name': 'Cryopreservation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004624', 'descriptor_name': 'Embryo Transfer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009845', 'descriptor_name': 'Oligospermia', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D009845', 'descriptor_name': 'Oligospermia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012662', 'descriptor_name': 'Semen Preservation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013081', 'descriptor_name': 'Sperm Motility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013737', 'descriptor_name': 'Testis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/humrep/deg260', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S127900037', 'display_name': 'Human Reproduction', 'issn_l': '0268-1161', 'issn': ['0268-1161', '1460-2350'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12773459', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.81}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W1523829460', 'https://openalex.org/W1544930851', 'https://openalex.org/W1580830605', 'https://openalex.org/W1584109455', 'https://openalex.org/W180046960', 'https://openalex.org/W1866911875', 'https://openalex.org/W1911176868', 'https://openalex.org/W1945512206', 'https://openalex.org/W1975417898', 'https://openalex.org/W1997768168', 'https://openalex.org/W2008689960', 'https://openalex.org/W2023492596', 'https://openalex.org/W2030955493', 'https://openalex.org/W2033845019', 'https://openalex.org/W2035332155', 'https://openalex.org/W2039607686', 'https://openalex.org/W2041426853', 'https://openalex.org/W2057974238', 'https://openalex.org/W2058658973', 'https://openalex.org/W2066672702', 'https://openalex.org/W2072515449', 'https://openalex.org/W2078593194', 'https://openalex.org/W2082213329', 'https://openalex.org/W2100265622', 'https://openalex.org/W2100938534', 'https://openalex.org/W2103823201', 'https://openalex.org/W2110845782', 'https://openalex.org/W2110865742', 'https://openalex.org/W2118704659', 'https://openalex.org/W2120865280', 'https://openalex.org/W2122835837', 'https://openalex.org/W2127323278', 'https://openalex.org/W2129440717', 'https://openalex.org/W2131594873', 'https://openalex.org/W2131670695', 'https://openalex.org/W2132649542', 'https://openalex.org/W2132898913', 'https://openalex.org/W2135937883', 'https://openalex.org/W2136208251', 'https://openalex.org/W2141266621', 'https://openalex.org/W2143004815', 'https://openalex.org/W2145148570', 'https://openalex.org/W2146335468', 'https://openalex.org/W2147274962', 'https://openalex.org/W2148333925', 'https://openalex.org/W2150756033', 'https://openalex.org/W2151282851', 'https://openalex.org/W2253549294', 'https://openalex.org/W2327762756', 'https://openalex.org/W2396959600'], 'related_works': ['https://openalex.org/W4283735483', 'https://openalex.org/W3141096188', 'https://openalex.org/W2744834612', 'https://openalex.org/W2129220528', 'https://openalex.org/W2104890888', 'https://openalex.org/W2019044222', 'https://openalex.org/W1994036839', 'https://openalex.org/W1989794563', 'https://openalex.org/W1984277315', 'https://openalex.org/W1583848893'], 'abstract_inverted_index': {'Patients': [0], 'persistently': [1], 'azoospermic': [2], 'after': [3, 54, 163], 'chemotherapy': [4, 55, 107, 164], 'have': [5, 175], 'been': [6, 114], 'considered': [7], 'traditionally': [8], 'as': [9], 'sterile': [10], 'unless': [11], 'sperm': [12, 25], 'was': [13, 46, 82, 148], 'frozen': [14], 'before': [15, 182], 'therapy.': [16], 'Recent': [17], 'advances': [18], 'during': [19], 'the': [20, 153, 187], 'last': [21], 'decade': [22], 'combining': [23], 'testicular': [24, 72, 78, 109], 'extraction': [26], '(TESE)': [27], 'and': [28, 60, 64, 77, 98, 111, 122, 145, 191], 'ICSI': [29, 89, 99, 138], 'in': [30, 133, 152], 'patients': [31, 50, 92, 159, 192], 'with': [32, 51, 70, 129, 160], 'non-obstructive': [33, 52], 'azoospermia': [34, 53, 162], 'allow': [35], 'these': [36], 'males': [37], 'to': [38, 127], 'father': [39], 'their': [40], 'own': [41], 'genetic': [42, 177], 'offspring.A': [43], 'retrospective': [44], 'study': [45], 'conducted': [47], 'of': [48, 103, 155, 189], '12': [49], 'undergoing': [56], 'TESE': [57, 81, 131], 'between': [58], '1995': [59], '2002.': [61], 'Cancer': [62], 'type': [63], 'anti-neoplastic': [65], 'treatments': [66], 'were': [67, 85, 100, 125, 140], 'recorded,': [68], 'together': [69], 'maximum': [71], 'volume,': [73], 'serum': [74], 'FSH': [75], 'levels': [76], 'histopathology.': [79], 'When': [80], 'successful,': [83], 'spermatozoa': [84, 95], 'cryopreserved': [86], 'for': [87, 96, 108, 118], 'performing': [88], 'later.In': [90], 'five': [91, 143], '(41.6%)': [93], 'motile': [94], 'cryopreservation': [97], 'retrieved.': [101], 'Four': [102], 'them': [104], 'had': [105, 113], 'received': [106], 'cancer,': [110], 'one': [112, 146], 'treated': [115, 168], 'by': [116, 169], 'chemotherapy/radiotherapy': [117], "Hodgkin's": [119], 'disease.': [120], 'Clinical': [121], 'histological': [123], 'parameters': [124], 'unable': [126], 'predict': [128], 'certainty': [130], 'outcome': [132], 'an': [134], 'individual': [135], 'patient.': [136], 'Eight': [137], 'cycles': [139], 'performed': [141], 'on': [142], 'couples': [144], 'pregnancy': [147], 'obtained': [149], 'which': [150], 'resulted': [151], 'delivery': [154], 'a': [156], 'healthy': [157], 'girl.Some': [158], 'permanent': [161], 'can': [165], 'be': [166, 194], 'successfully': [167], 'TESE-ICSI.': [170], 'This': [171], 'procedure,': [172], 'however,': [173], 'may': [174], 'potential': [176], 'risks.': [178], 'Therefore,': [179], 'freezing': [180], 'semen': [181], 'starting': [183], 'gonadotoxic': [184], 'therapy': [185], 'is': [186], 'strategy': [188], 'choice,': [190], 'should': [193], 'counselled': [195], 'accordingly.': [196]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2168847156', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 11}, {'year': 2013, 'cited_by_count': 17}, {'year': 2012, 'cited_by_count': 16}], 'updated_date': '2025-01-09T19:27:24.218889', 'created_date': '2016-06-24'}