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'descriptor_name': 'Brain', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016718', 'descriptor_name': 'Arachidonic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016718', 'descriptor_name': 'Arachidonic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016367', 'descriptor_name': 'Baculoviridae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018076', 'descriptor_name': 'DNA, Complementary', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D018076', 'descriptor_name': 'DNA, Complementary', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 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{'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006899', 'descriptor_name': 'Mixed Function Oxygenases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008970', 'descriptor_name': 'Molecular Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011689', 'descriptor_name': 'Purkinje Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011689', 'descriptor_name': 'Purkinje Cells', 'qualifier_ui': 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'https://openalex.org/W2014499427', 'https://openalex.org/W2006953355', 'https://openalex.org/W1969886452'], 'abstract_inverted_index': {'A': [0, 255, 3418, 4063], 'cDNA': [1, 21, 256, 276, 1671, 1838, 1856, 1943, 2079, 2086, 2093, 2099, 2114, 2174, 2186, 2321, 3450, 3483], 'encoding': [2, 257], 'a': [3, 10, 23, 52, 126, 153, 211, 258, 265, 278, 307, 381, 408, 466, 634, 1404, 1409, 1553, 1631, 1678, 1852, 1920, 2009, 2155, 2336, 2485, 2572, 2857, 2863, 2887, 3005, 3065, 3566, 3669, 3689, 3769, 3815], 'new': [4, 259, 1679], 'cytochrome': [5, 260, 518, 1034, 1405], 'P450': [6, 46, 214, 261, 301, 469, 519, 521, 532, 1046, 1406, 1681, 2542, 3093, 3782], 'was': [7, 42, 262, 297, 1849, 2065, 2070, 2087, 2115, 2151, 2195, 2329, 2356, 2544, 2668, 2807, 2844, 2879, 2999, 3111, 3351, 3375, 3396, 3485, 3557, 3695, 4075, 4088], 'isolated': [8, 263, 1918, 3140], 'from': [9, 71, 264, 326, 1583, 1787, 1795, 1809, 1816, 1827, 1842, 2881, 2919, 3138, 3324, 3796, 4160, 4321], 'mouse': [11, 86, 149, 266, 341, 404, 1680, 1836, 3141, 3308, 3515, 3748, 3760, 3798], 'brain': [12, 89, 106, 137, 150, 267, 344, 361, 392, 405, 1060, 1245, 1413, 1692, 1837, 3191, 3350], 'library.': [13, 268], 'Sequence': [14, 269], 'analysis': [15, 75, 97, 270, 330, 352, 2995], 'reveals': [16, 76, 164, 271, 331, 419], 'that': [17, 28, 77, 99, 121, 130, 184, 208, 215, 234, 243, 272, 283, 332, 354, 376, 385, 439, 463, 470, 489, 498, 1416, 1532, 1555, 1682, 1715, 1731, 1769, 2012, 2067, 2164, 2683], 'this': [18, 273, 2068, 2362, 4108], '1,958-base': [19, 274], 'pair': [20, 275], 'encodes': [22, 277], '57–58-kDa': [24, 279], '502-amino': [25, 280], 'acid': [26, 61, 64, 246, 281, 316, 319, 501, 511, 513, 539, 562, 1037, 1051, 1624, 1702, 1784, 1863, 2506, 2647, 3096, 3104, 3126, 3129, 3198], 'polypeptide': [27, 282, 4064], 'is': [29, 37, 68, 131, 140, 210, 216, 284, 292, 323, 386, 395, 465, 471, 1031, 1683, 2368, 2379], '70–91%': [30, 285], 'identical': [31, 286, 2144, 3098], 'to': [32, 62, 187, 221, 287, 317, 442, 476, 540, 647, 974, 1055, 1238, 1314, 1703, 1722, 1747, 2226, 2532, 2548, 2639, 2670, 2681, 2846, 2883, 2924, 3385, 3435, 3537, 3548, 3647, 3730, 3743, 3755, 3789, 3800, 3911, 4066, 4093, 4097], 'CYP2J': [33, 288, 2061, 3915], 'subfamily': [34, 289, 1233, 2062, 3916], 'P450s': [35, 290, 2022, 3917, 4306], 'and': [36, 107, 135, 139, 156, 168, 195, 225, 291, 362, 390, 394, 411, 423, 450, 480, 546, 555, 567, 580, 597, 615, 685, 854, 886, 944, 980, 1072, 1231, 1307, 1326, 1419, 1487, 1539, 1586, 1641, 1673, 1694, 1712, 1718, 1754, 1782, 1823, 1886, 1909, 1929, 1974, 1986, 2018, 2105, 2132, 2172, 2213, 2333, 2348, 2394, 2400, 2507, 2517, 2530, 2553, 2645, 2699, 2705, 2790, 2799, 2854, 2903, 2915, 2931, 2939, 2950, 3056, 3060, 3080, 3116, 3127, 3146, 3160, 3194, 3211, 3295, 3304, 3320, 3327, 3341, 3372, 3398, 3474, 3498, 3591, 3593, 3624, 3627, 3661, 3711, 3717, 3735, 3780, 3810, 3850, 3873, 3923, 3939, 4091, 4171, 4326], 'designated': [38, 293], 'CYP2J9.': [39, 294], 'Recombinant': [40, 295], 'CYP2J9': [41, 67, 78, 100, 124, 166, 209, 244, 296, 322, 333, 355, 379, 421, 464, 499, 1716, 1770, 2320, 2378, 2516, 3449, 3528, 3542, 3553, 4073], 'co-expressed': [43, 298], 'with': [44, 123, 152, 159, 299, 378, 407, 414, 1422, 1851, 1967, 2015, 2059, 2189, 2197, 2390, 2494, 2527, 2794, 2862, 2892, 3024, 3064, 3094, 3123, 3299, 3445, 3487, 3559, 3913, 3929, 4081, 4165], 'NADPH-cytochrome': [45, 300, 520], 'oxidoreductase': [47, 302, 522], '(CYPOR)': [48, 303], 'in': [49, 85, 105, 110, 133, 170, 191, 198, 218, 227, 252, 304, 340, 360, 365, 388, 425, 446, 453, 473, 482, 507, 628, 652, 680, 790, 983, 1039, 1059, 1243, 1304, 1412, 1536, 1590, 1627, 1686, 1696, 1709, 1725, 1751, 1757, 1776, 1870, 2134, 2191, 2481, 2501, 3148, 3400, 3458, 3565, 3615, 3814, 3868, 4115, 4309], 'Sf9cells': [50, 305, 2387, 2582], 'using': [51, 114, 306, 369, 1708, 1919, 1956, 2095, 2122, 2223, 2571, 2815, 3004, 3358, 3377, 3489, 3500, 3517, 3768, 4120], 'baculovirus': [53, 308, 2499], 'system.': [54, 309, 1043], 'Microsomes': [55, 310, 4158], 'of': [56, 148, 179, 230, 237, 311, 403, 434, 485, 492, 537, 560, 636, 1049, 1064, 1318, 1543, 1558, 1565, 1581, 1676, 1700, 1737, 1761, 1847, 1889, 1900, 2000, 2077, 2092, 2139, 2147, 2157, 2169, 2177, 2350, 2366, 2377, 2487, 2504, 2551, 2687, 2690, 2796, 2889, 2897, 2996, 3068, 3190, 3301, 3477, 3513, 3540, 3551, 3562, 3587, 3596, 3618, 3630, 3650, 3706, 3709, 3713, 3737, 3746, 3758, 3931, 4070], 'CYP2J9/CYPOR-transfected': [57, 312], 'cells': [58, 194, 313, 449, 1415, 1724, 1753, 2194, 2479, 4163], 'metabolize': [59, 314], 'arachidonic': [60, 245, 315, 500, 538, 561, 1036, 1050, 1623, 1701, 3095], '19-hydroxyeicosatetraenoic': [63, 318], '(HETE)': [65, 320], 'thus': [66, 321], 'enzymologically': [69, 324], 'distinct': [70, 325], 'other': [72, 136, 327, 391, 1821, 2060], 'P450s.': [73, 328, 4085], 'Northern': [74, 329, 3390, 3505], 'transcripts': [79, 334], 'are': [80, 102, 185, 196, 335, 357, 440, 451, 626, 1053, 1302, 1400, 1417, 1720, 1745, 1755, 3058], 'present': [81, 336], 'at': [82, 337, 1867, 1905, 2074, 2341, 2484, 2539, 2657, 2886, 3030, 3201, 3455, 3604, 3641, 3653, 3658, 3664, 3673], 'high': [83, 338, 514, 2495], 'levels': [84, 339, 3784], 'brain.': [87, 342, 1778], 'Mouse': [88, 343, 2096], 'microsomes': [90, 345, 2635, 3079, 3084], 'biosynthesize': [91, 346], '19-HETE.': [92, 347, 1704], 'RNA': [93, 348, 3374, 3393, 3520, 3564], 'polymerase': [94, 349, 525, 1806, 1970], 'chain': [95, 350, 526], 'reaction': [96, 351, 527, 2701], 'demonstrates': [98, 353], 'mRNAs': [101, 356], 'widely': [103, 358], 'distributed': [104, 359], 'most': [108, 363], 'abundant': [109, 165, 217, 364, 420, 472], 'the': [111, 160, 177, 228, 253, 366, 415, 432, 483, 508, 534, 642, 653, 681, 791, 984, 1040, 1065, 1244, 1305, 1316, 1540, 1566, 1576, 1621, 1670, 1687, 1697, 1726, 1735, 1759, 1777, 1957, 2001, 2075, 2078, 2081, 2106, 2119, 2123, 2140, 2166, 2170, 2178, 2182, 2198, 2214, 2325, 2342, 2351, 2364, 2371, 2375, 2383, 2391, 2502, 2549, 2672, 2684, 2688, 2700, 2804, 2818, 2842, 2847, 2913, 2920, 2925, 3050, 3117, 3349, 3354, 3386, 3441, 3446, 3490, 3518, 3541, 3552, 3616, 3698, 3721, 3733, 3747, 3759, 3790, 3857, 3932, 4071, 4327], 'cerebellum.': [112, 367, 1727], 'Immunoblotting': [113, 368], 'an': [115, 232, 370, 487, 1949, 2893, 3635], 'antibody': [116, 371, 3906], 'raised': [117, 372, 3867, 4114], 'against': [118, 373, 3856, 4107], 'human': [119, 374, 2017, 3861], 'CYP2J2': [120, 162, 375, 417, 3862], 'cross-reacts': [122, 377], 'detects': [125, 380], '56-kDa': [127, 382], 'protein': [128, 169, 383, 424, 1719, 2179, 3863], 'band': [129, 384], 'expressed': [132, 189, 387, 444, 1057, 1685, 1750], 'cerebellum': [134, 389], 'segments': [138, 393], 'regulated': [141, 213, 396, 468, 1689], 'during': [142, 397, 1690], 'postnatal': [143, 398, 1691], 'development.': [144, 399], 'In': [145, 400, 1225, 1618, 2361, 2802, 3100], 'situ': [146, 401, 1710], 'hybridization': [147, 402, 1711], 'sections': [151, 406, 3357], 'CYP2J9-specific': [154, 409, 4109], 'riboprobe': [155, 410], 'immunohistochemical': [157, 412, 1713], 'staining': [158, 413], 'anti-human': [161, 416], 'IgG': [163, 418], 'mRNA': [167, 422, 1717, 3783], 'cerebellar': [171, 192, 222, 426, 447, 477], 'Purkinje': [172, 193, 223, 427, 448, 478, 1723, 1752], 'cells.': [173, 428], 'Importantly,': [174, 429, 1728], '19-HETE': [175, 430, 969, 1732, 2806, 2843, 2916], 'inhibits': [176, 235, 431, 490, 1734], 'activity': [178, 236, 433, 491, 1736], 'recombinant': [180, 435, 1738, 2401, 2498, 2515, 2585, 3086, 3860, 4166, 4305], 'P/Q-type': [181, 238, 436, 493, 1739], 'Ca2+': [182, 239, 437, 494, 1582, 1588, 1639, 1740], 'channels': [183, 438, 898, 1640, 1743], 'known': [186, 441, 1032, 1054, 1746, 3914, 4082], 'be': [188, 443, 1056, 1239, 1748], 'preferentially': [190, 445, 1749], 'involved': [197, 452, 1756], 'triggering': [199, 454, 1758], 'neurotransmitter': [200, 455], 'release.': [201, 456], 'Based': [202, 457, 1763, 2056], 'on': [203, 458, 977, 1764, 1948, 2057, 2856, 3001, 3131, 3681], 'these': [204, 459, 1765, 3048], 'data,': [205, 460, 1766], 'we': [206, 461, 1668, 1729, 1767], 'conclude': [207, 462], 'developmentally': [212, 467], 'brain,': [219, 474, 1688, 3311], 'localized': [220, 475, 1721], 'cells,': [224, 479], 'active': [226, 481, 1695], 'biosynthesis': [229, 484], '19-HETE,': [231, 486], 'eicosanoid': [233, 488], 'channels.': [240, 495, 1563], 'We': [241, 496, 1705], 'postulate': [242, 497, 1768], 'products': [247, 502, 1771, 2702, 2783, 3118, 3208, 3288, 3678], 'play': [248, 503, 1772], 'important': [249, 504, 1773], 'functional': [250, 505, 1537, 1774], 'roles': [251, 506, 1775], 'brain.AF336850': [254, 509], 'cis-epoxyeicosatrienoic': [510, 541], 'hydroxyeicosatetraenoic': [512], 'performance': [515], 'liquid': [516, 2953], 'chromatography': [517], 'pentafluorobenzyl': [523, 2849], 'kilobase': [524], 'gas': [528, 2820, 2877], 'chromatography/mass': [529], 'spectroscopy': [530], 'Cytochromes': [531], 'catalyze': [533], 'NADPH-dependent': [535], 'oxidation': [536], 'acids': [542, 4068], '(5,6-,': [543], '8,9-,': [544], '11,12-,': [545], '14,15-EET),1': [547], 'mid-chaincis-trans-conjugated': [548], 'dienols': [549], '(5-,': [550], '8-,': [551], '9-,': [552], '11-,': [553], '12-,': [554], '15-HETE),': [556], 'and/or': [557], 'ω-terminal': [558], 'alcohols': [559], '(16-,': [563], '17-,': [564], '18-,': [565], '19-,': [566], '20-HETE)': [568], '(1Capdevila': [569], 'J.H.': [570, 841, 2959, 2983], 'Falck': [571, 689, 706, 730, 770, 797, 842, 903, 929, 954, 994, 1009, 1338, 1359, 1386, 1449, 1493, 1598, 2244, 2421, 2726, 2964, 2980, 3231, 3885, 3981, 4043, 4218, 4280], 'J.R.': [572, 656, 690, 707, 731, 771, 798, 843, 904, 930, 955, 995, 1010, 1339, 1360, 1387, 1450, 1494, 1599, 2245, 2422, 2727, 2965, 2981, 3232, 3886, 3982, 4044, 4219, 4281], 'Estabrook': [573, 2041], 'R.W.': [574, 2042], 'FASEB': [575], 'J.': [576, 660, 664, 692, 717, 734, 781, 808, 822, 823, 847, 914, 934, 958, 999, 1083, 1186, 1254, 1292, 1333, 1366, 1383, 1435, 1458, 1468, 1502, 1512, 1602, 1650, 1657, 2241, 2250, 2267, 2284, 2418, 2427, 2444, 2461, 2559, 2723, 2732, 2749, 2766, 2831, 3037, 3228, 3237, 3254, 3271, 3413, 3889, 3978, 3987, 4004, 4021, 4047, 4125, 4142, 4215, 4224, 4241, 4258, 4284], '1992;': [577, 1460, 1504], '6': [578], '(,': [579, 596, 614], 'references': [581, 598, 616], 'therein):': [582, 599, 617], '731-736Crossref': [583], 'PubMed': [584, 601, 619, 672, 743, 759, 829, 878, 939, 964, 1004, 1024, 1091, 1105, 1121, 1137, 1157, 1173, 1197, 1220, 1262, 1350, 1371, 1394, 1440, 1481, 1525, 1613, 2051, 2261, 2295, 2314, 2438, 2472, 2568, 2607, 2743, 2777, 2836, 2971, 2989, 3042, 3248, 3282, 3900, 3962, 3998, 4032, 4058, 4153, 4199, 4235, 4269, 4295], 'Scopus': [585, 602, 620, 673, 698, 760, 830, 879, 940, 965, 1025, 1092, 1106, 1122, 1138, 1158, 1174, 1198, 1221, 1263, 1351, 1372, 1395, 1441, 1482, 1526, 1614, 1663, 2052, 2262, 2296, 2315, 2439, 2473, 2608, 2744, 2778, 2837, 2972, 2990, 3043, 3249, 3283, 3901, 3963, 3999, 4033, 4059, 4154, 4200, 4236, 4270, 4296], '(276)': [586], 'Google': [587, 604, 622, 675, 700, 722, 744, 762, 813, 832, 852, 881, 919, 942, 967, 1005, 1027, 1094, 1108, 1124, 1140, 1160, 1176, 1200, 1223, 1265, 1282, 1299, 1353, 1374, 1397, 1443, 1463, 1484, 1507, 1528, 1616, 1665, 2054, 2264, 2298, 2317, 2441, 2475, 2569, 2610, 2746, 2780, 2839, 2974, 2992, 3045, 3251, 3285, 3903, 3965, 4001, 4035, 4061, 4156, 4202, 4238, 4272, 4298], 'Scholar,': [588, 605, 701, 723, 745, 763, 814, 833, 920, 1006, 1095, 1109, 1125, 1141, 1161, 1177, 1201, 1266, 1283, 1354, 1375, 1444, 1464, 1508, 2265, 2299, 2442, 2747, 2975, 3252, 3966, 4002, 4036, 4203, 4239, 4273], '2Oliw': [589], 'E.H.': [590, 3036], 'Prog.': [591], 'Lipid': [592], 'Res.': [593, 667, 694, 755, 1019, 1100, 1116], '1994;': [594], '33': [595], '329-354Crossref': [600], '(139)': [603], '3McGiff': [606], 'J.C.': [607, 733, 957, 997], 'Annu.': [608], 'Rev.': [609], 'Pharmacol.': [610, 935, 960, 1133, 1153, 1169, 1278, 1293], 'Toxicol.': [611], '1991;': [612, 2833, 2968], '31': [613, 3333], '339-369Crossref': [618], '(288)': [621], 'Scholar).': [623, 882, 968, 1028, 1224, 1300, 1398, 1485, 1617, 1666, 2055, 2318, 2476, 2611, 2781, 2840, 2993, 3046, 3286, 3431, 3904, 4062, 4157, 4299], 'These': [624], 'eicosanoids': [625], 'biosynthesized': [627, 1303], 'numerous': [629], 'tissues': [630, 3309], 'where': [631, 1309], 'they': [632, 1310], 'possess': [633], 'myriad': [635], 'potent': [637], 'biological': [638], 'activities.': [639], 'For': [640, 2910, 3346, 3389, 4300], 'example,': [641], 'EETs': [643, 1301, 1399, 1534, 1567, 2914], 'have': [644, 855, 975, 1235, 1311, 1530], 'been': [645, 972, 1236, 1312, 1570, 3908], 'shown': [646, 1237, 1313, 3909], 'control': [648, 3731], 'peptide': [649, 4087, 4110], 'hormone': [650, 1329], 'secretion': [651], 'pancreas': [654], '(4Falck': [655], 'Manna': [657, 1336, 1361], 'S.': [658, 1145, 1213, 1337, 1345, 1362, 2231, 2237, 2408, 2414, 2713, 2719, 2826, 3218, 3224, 3880, 3968, 3974, 4038, 4205, 4211, 4275], 'Moltz': [659], 'Chacos': [661, 1334, 1363], 'N.': [662, 1335, 1364], 'Capdevila': [663, 691, 821, 840, 1332, 1365, 1382, 2982], 'Biochem.': [665, 1017, 1085, 1098, 1114, 1132, 1152, 1168, 1256, 2309, 2602, 2985], 'Biophys.': [666, 1018, 1099, 1115, 2310, 2603], 'Commun.': [668, 1020, 1101, 1117], '1983;': [669, 1347], '114:': [670], '743-749Crossref': [671], '(147)': [674], 'Scholar),': [676, 786, 853], 'regulate': [677], 'vascular': [678, 978, 1559, 1635], 'tone': [679, 979], 'intestine,': [682, 3318], 'kidney,': [683, 3313], 'heart,': [684, 3315], 'lung': [686], '(5Proctor': [687], 'K.G.': [688], 'Circ.': [693, 754], '1986;': [695], '60:': [696], '50-59Crossref': [697], '(153)': [699], '6Zou': [702], 'A.': [703, 765, 794, 900, 1080, 1251, 1346, 1356, 2963], 'Fleming': [704, 795, 901], 'J.T.': [705, 796, 902], 'Jacobs': [708, 778, 799, 905, 1653], 'E.R.': [709, 779, 800, 906, 1654], 'Gebremedhin': [710, 748, 801, 907, 1469, 1513], 'D.': [711, 749, 802, 908, 953, 1446, 1470, 1490, 1514, 1646], 'Harder': [712, 752, 774, 803, 909, 1455, 1475, 1486, 1499, 1519, 1655], 'D.R.': [713, 753, 775, 804, 910, 1183, 1456, 1476, 1500, 1520, 1656, 2024], 'Roman': [714, 776, 805, 911, 1451, 1473, 1495, 1517], 'R.J.': [715, 777, 806, 912, 1209, 1452, 1474, 1496, 1518], 'Am.': [716, 780, 807, 846, 913, 998, 1457, 1501], 'Physiol.': [718, 782, 809, 825, 848, 915, 1000, 1459, 1503, 1658], '1996;': [719, 756, 810, 916, 1001, 1189, 1478, 1522, 2048, 3892, 4050, 4287], '270:': [720, 811, 917], 'F822-F832PubMed': [721, 812], '7Carroll': [724], 'M.A.': [725, 987], 'Balazy': [726, 988], 'M.': [727, 767, 773, 867, 989, 1016, 1076, 1078, 1097, 1247, 1249, 1272, 1454, 1472, 1498, 1516, 3951, 4188], 'Margiotta': [728, 990], 'P.': [729, 991, 1012, 1215], 'McGiff': [732, 956, 996], 'Biol.': [735, 1087, 1187, 1258, 1603, 2251, 2285, 2428, 2462, 2560, 2733, 2767, 3238, 3272, 3890, 3988, 4022, 4048, 4143, 4225, 4259, 4285], 'Chem.': [736, 1188, 1604, 2252, 2286, 2429, 2463, 2561, 2734, 2768, 3239, 3273, 3891, 3989, 4023, 4049, 4144, 4226, 4260, 4286], '1993;': [737, 936, 961, 1088, 1102, 1259, 1437], '268:': [738, 850], '12260-12266Abstract': [739], 'Full': [740, 1192, 1194, 1608, 1610, 2256, 2258, 2290, 2292, 2433, 2435, 2467, 2469, 2565, 2738, 2740, 2772, 2774, 3243, 3245, 3277, 3279, 3895, 3897, 3993, 3995, 4027, 4029, 4053, 4055, 4148, 4150, 4230, 4232, 4264, 4266, 4290, 4292], 'Text': [741, 1193, 1195, 1609, 1611, 2257, 2259, 2291, 2293, 2434, 2436, 2468, 2470, 2566, 2739, 2741, 2773, 2775, 3244, 3246, 3278, 3280, 3896, 3898, 3994, 3996, 4028, 4030, 4054, 4056, 4149, 4151, 4231, 4233, 4265, 4267, 4291, 4293], 'PDF': [742, 1196, 1612, 2260, 2294, 2437, 2471, 2567, 2742, 2776, 3247, 3281, 3899, 3997, 4031, 4057, 4152, 4234, 4268, 4294], '8Campbell': [746], 'W.B.': [747], 'Pratt': [750], 'P.F.': [751], '78:': [757], '415-423Crossref': [758], '(1115)': [761], '9Zou': [764], 'Bousamra': [766], 'Zeldin': [768, 870, 2248, 2282, 2425, 2459, 2730, 2764, 3235, 3269, 3887, 3954, 3985, 4019, 4045, 4140, 4191, 4222, 4256, 4282], 'D.C.': [769, 871, 1207, 2249, 2283, 2426, 2460, 2731, 2765, 3236, 3270, 3888, 3955, 3986, 4020, 4046, 4141, 4192, 4223, 4257, 4283], 'Townsley': [772], '2000;': [783, 1170, 1217, 1296], '278:': [784], 'L335-L343Google': [785], 'affect': [787], 'ion': [788, 948, 981, 2811, 2905], 'transport': [789, 949, 982], 'kidney': [792, 985], '(6Zou': [793], '10Harris': [815], 'R.C.': [816], 'Homma': [817], 'T.': [818, 1276, 2028, 2556, 3411], 'Jacobson': [819, 836], 'H.R.': [820, 837], 'Cell.': [824], '1990;': [826, 1391, 3039], '144:': [827], '429-437Crossref': [828], '(92)': [831], '11Sakairi': [834], 'Y.': [835, 861, 3945, 4182], 'Noland': [838], 'T.D.': [839, 2977], 'Breyer': [844, 2280, 2457, 2762, 3267, 4017, 4138, 4254], 'M.D.': [845, 2281, 2458, 2763, 3268, 4018, 4139, 4255], '1995;': [849, 1118, 2311, 2604], 'F931-F939PubMed': [851], 'anti-inflammatory': [856], 'properties': [857, 2793, 3298], '(12Node': [858, 3942, 4179], 'K.': [859, 869, 924, 3943, 3953, 4180, 4190], 'Huo': [860, 3944, 4181], 'Ruan': [862, 3946, 4183], 'X.': [863, 3947, 4184], 'Yang': [864, 3948, 4185], 'B.': [865, 922, 951, 1008, 1285, 3949, 4186], 'Spiecker': [866, 3950, 4187], 'Ley': [868, 3952, 4189], 'Liao': [872, 3956, 4193], 'J.K.': [873, 3957, 4194], 'Science.': [874, 3958, 4195], '1999;': [875, 1605, 2287, 2464, 2769, 3274, 3959, 4024, 4145, 4196, 4261], '285:': [876, 3960, 4197], '1276-1279Crossref': [877, 3961, 4198], '(1024)': [880, 3964, 4201], '20-HETE': [883], 'constricts': [884], 'renal': [885, 946], 'aortic': [887], 'vessels': [888], 'by': [889, 1241, 1403, 1547, 1630, 1934, 1983, 2089, 2181, 2204, 2331, 2358, 2370, 2382, 2536, 2707, 2786, 2809, 2933, 2947, 2952, 3074, 3121, 3143, 3213, 3291, 3343, 3510, 3668, 3787, 3812, 4100], 'inhibiting': [890], 'smooth': [891, 1560, 1636], 'muscle': [892, 1561, 1637], 'cell': [893, 2634, 3078, 3083], 'large': [894], 'conductance': [895], 'Ca2+-activated': [896], 'K+': [897, 1562], '(13Zou': [899], 'R228-R237PubMed': [918], '14Escalante': [921], 'Omata': [923], 'Sessa': [925], 'W.': [926, 2233, 2269, 2410, 2446, 2715, 2751, 3220, 3256, 3970, 4006, 4127, 4207, 4243], 'Lee': [927], 'S.-G.': [928], 'Schwartzman': [931], 'M.L.': [932], 'Eur.': [933], '235:': [937], '1-7Crossref': [938], '(65)': [941, 1123], 'Scholar)': [943, 1529, 2570], 'affects': [945], 'tubular': [947], '(15Escalante': [950], 'Erlij': [952], 'Cardiovasc.': [959], '22:': [962], 'S106-S108Crossref': [963], '(11)': [966], 'has': [970, 1568, 3907], 'also': [971, 1401, 1569], 'reported': [973], 'effects': [976], '(16Carroll': [986], 'Huang': [992, 2825], 'D.-D.': [993], '271:': [1002, 1190, 3893, 4051, 4288], 'R863-R869Crossref': [1003], '17Escalante': [1007], 'Yadagiri': [1011], 'Sun': [1013], 'L.': [1014, 2026], 'Laniado-Schwartzman': [1015], '1988;': [1021, 1279], '152:': [1022], '1269-1274Crossref': [1023], '(74)': [1026], 'Remarkably': [1029], 'little': [1030], 'about': [1033], 'P450-dependent': [1035], 'metabolism': [1038, 1052], 'central': [1041], 'nervous': [1042], 'Multiple': [1044], 'different': [1045, 2675], 'isoforms': [1047], 'capable': [1048], 'constitutively': [1058], 'tissue': [1061, 4302], 'including': [1062, 1321, 1803, 2080, 2324], 'members': [1063, 1234, 3930], 'CYP1A,': [1066, 1227, 3933], 'CYP2B,': [1067, 1228, 3935], 'CYP2C,': [1068, 1229, 3936], 'CYP2D,': [1069, 3937], 'CYP2E,': [1070, 1230, 3938], 'CYP4A,': [1071], 'CYP4F': [1073], 'subfamilies': [1074, 3941], '(18Warner': [1075, 1246], 'Stromstedt': [1077, 1248], 'Wyss': [1079, 1250], 'Gustafsson': [1081, 1252, 1273], 'J.-A.': [1082, 1253, 1274], 'Steroid': [1084, 1255], 'Mol.': [1086, 1257, 1277], '47:': [1089, 1260], '191-194Crossref': [1090, 1261], '(34)': [1093, 1264], '19Komori': [1096], '196:': [1103], '721-728Crossref': [1104], '(53)': [1107, 1373], '20Kawashima': [1110], 'H.': [1111, 1179, 1270], 'Strobel': [1112, 1184], 'H.W.': [1113, 1185], '217:': [1119], '1137-1144Crossref': [1120], '21McFayden': [1126], 'M.C.': [1127], 'Melvin': [1128], 'W.T.': [1129], 'Murray': [1130], 'G.I.': [1131], '1998;': [1134, 1154, 1660], '55:': [1135], '825-830Crossref': [1136], '(98)': [1139], '22Tirumalai': [1142], 'P.S.': [1143], 'Bhamre': [1144], 'Upadhya': [1146], 'S.C.': [1147, 1426], 'Boyd': [1148, 1164], 'M.R.': [1149, 1165, 1287, 1652, 2036], 'Ravindranath': [1150, 1166], 'V.': [1151, 1167], '56:': [1155], '371-375Crossref': [1156], '(25)': [1159], '23Bhagwat': [1162], 'S.V.': [1163], '59:': [1171], '573-582Crossref': [1172], '(48)': [1175], '24Kawashima': [1178], 'Sequeira': [1180], 'D.J.': [1181, 2034], 'Nelson': [1182], '28176-28180Abstract': [1191], '(50)': [1199], '25Riedl': [1202], 'A.G.': [1203], 'Watts': [1204], 'P.M.': [1205], 'Douek': [1206], 'Edwards': [1208], 'Boobis': [1210], 'A.R.': [1211, 1648], 'Rose': [1212], 'Jenner': [1214], 'Synapse.': [1216], '38:': [1218], '392-402Crossref': [1219], '(0)': [1222], 'addition,': [1226, 2803], 'CYP4A': [1232, 1632, 3940], 'inducible': [1240], 'xenochemicals': [1242], '26Naslund': [1267], 'B.M.A.': [1268], 'Glaumann': [1269], 'Warner': [1271], 'Hansson': [1275], '33:': [1280], '31-37PubMed': [1281], '27Schilter': [1284], 'Andersen': [1286], 'Acharya': [1288], 'C.': [1289, 2243, 2301, 2420, 2594, 2725, 3230, 3980, 4217], 'Omiecinski': [1290], 'C.J.': [1291, 2307, 2600], 'Exp.': [1294], 'Ther.': [1295], '294:': [1297], '916-922PubMed': [1298], 'pituitary': [1306], 'hypothalamus': [1308], 'stimulate': [1315], 'release': [1317, 1580, 1760], 'various': [1319], 'neuropeptides': [1320], 'somatostatin,': [1322], 'arginine': [1323], 'vasopressin,': [1324], 'oxytocin,': [1325], 'luteinizing': [1327], 'hormone-releasing': [1328], '(28Snyder': [1330], 'G.D.': [1331, 1358], 'Proc.': [1340], 'Natl.': [1341], 'Acad.': [1342], 'Sci.': [1343], 'U.': [1344], '80:': [1348], '3504-3507Crossref': [1349], '(127)': [1352], '29Negro-Vilar': [1355], 'Snyder': [1357], 'Endocrinology.': [1367, 1390], '1985;': [1368], '116:': [1369], '2663-2668Crossref': [1370], '30Junier': [1376], 'M.-P.': [1377], 'Dray': [1378], 'F.': [1379], 'Blair': [1380, 2978], 'I.': [1381], 'Dishman': [1384, 2960], 'E.': [1385, 2235, 2412, 2717, 2961, 3222, 3972, 4209], 'Ojeda': [1388], 'S.R.': [1389], '126:': [1392], '1534-1540Crossref': [1393], '(58)': [1396], 'produced': [1402, 1626], '(most': [1407], 'likely': [1408], 'CYP2C': [1410], 'isoform)': [1411], 'astrocytes,': [1414], 'anatomically': [1418], 'functionally': [1420], 'associated': [1421], 'cerebral': [1423, 1544, 1550, 1628, 1643, 3365, 3804], 'microvessels': [1424], '(31Amruthesh': [1425], 'Boerschel': [1427], 'M.F.': [1428], 'McKinney': [1429], 'J.S.': [1430], 'Willoughby': [1431, 1594], 'K.A.': [1432, 1595], 'Ellis': [1433, 1600], 'E.F.': [1434, 1601, 3415], 'Neurochem.': [1436], '61:': [1438], '150-159Crossref': [1439], '(109)': [1442], '32Gebremedhin': [1445], 'Ma': [1447, 1491], 'Y.-H.': [1448, 1492], 'VanRollins': [1453, 1497], '263:': [1461, 1505], 'H519-H525PubMed': [1462, 1506], '33Alkayed': [1465, 1509], 'N.J.': [1466, 1510], 'Narayanan': [1467, 1511, 1649], 'Medhora': [1471, 1515], 'Stroke.': [1477, 1521], '27:': [1479, 1523], '971-979Crossref': [1480, 1524], '(174)': [1483, 1527], 'colleagues': [1488], '(32Gebremedhin': [1489], 'proposed': [1531, 1571], 'astrocyte-derived': [1533], 'participate': [1535], 'hyperemia': [1538], 'local': [1541], 'regulation': [1542], 'blood': [1545], 'flow': [1546], 'dilating': [1548], 'adjacent': [1549], 'arterioles': [1551], 'through': [1552], 'mechanism': [1554], 'involves': [1556], 'activation': [1557], 'One': [1564, 1999], 'as': [1572, 2405, 2591, 2710, 2817, 2821, 2955, 3033, 3215, 3362, 3408, 3720, 3876, 4176], 'calcium': [1573], 'influx': [1574], 'factor,': [1575], 'elusive': [1577], 'link': [1578], 'between': [1579], 'intracellular': [1584], 'stores': [1585], 'capacitative': [1587], 'influx,': [1589], 'astrocytes': [1591], '(34Rzigalinski': [1592], 'B.A.': [1593], 'Hoffman': [1596], 'S.W.': [1597], '274:': [1606, 2288, 2465, 2770, 3275, 4025, 4146, 4262], '175-182Abstract': [1607], '(121)': [1615], 'contrast,': [1619], '20-HETE,': [1620], 'primary': [1622], 'metabolite': [1625], 'arteries': [1629], 'isoform,': [1633], 'activates': [1634], 'L-type': [1638], 'promotes': [1642], 'vasoconstriction': [1644], '(35Gebremedhin': [1645], 'Lange': [1647], 'Aebly': [1651], '(Lond.).': [1659], '507:': [1661], '771-781Crossref': [1662], '(171)': [1664], 'Herein,': [1667], 'report': [1669], 'cloning': [1672], 'heterologous': [1674], 'expression': [1675, 2353, 2365, 2376], 'CYP2J9,': [1677], 'primarily': [1684], 'development,': [1693], 'ω-1': [1698], 'hydroxylation': [1699], 'further': [1706], 'demonstrate,': [1707], 'techniques,': [1714], 'show': [1730], 'significantly': [1733], 'channels,': [1741], 'voltage-gated': [1742], 'which': [1744, 1901, 2148], 'neurotransmitters.': [1762], '[α-32P]dATP,': [1779], '[1-14C]arachidonic': [1780, 2646, 3114, 3197], 'acid,': [1781, 3115], '[1-14C]linoleic': [1783, 3103], 'were': [1785, 1793, 1807, 1814, 1825, 1865, 1898, 1907, 1917, 1932, 1945, 1981, 2388, 2403, 2491, 2519, 2589, 2654, 2697, 2703, 2784, 2908, 2917, 2942, 3072, 3119, 3136, 3199, 3209, 3289, 3322, 3443, 3453, 3508, 3531, 3613, 3645, 3679, 3728, 3766, 3785, 3794, 3866, 4113, 4174, 4307, 4330], 'purchased': [1786, 1794, 1808, 1815, 1826, 4320], 'PerkinElmer': [1788, 1810], 'Life': [1789, 1811, 1817, 1972, 3524], 'Sciences.': [1790, 1812], 'Restriction': [1791], 'enzymes': [1792], 'New': [1796, 3869, 4116], 'England': [1797], 'Biolabs': [1798], '(Beverly,': [1799], 'MA).': [1800], 'PCR': [1801, 2332, 3511, 3521, 3611, 3677], 'reagents': [1802, 1824], 'AmpliTaq®': [1804, 1968, 3631], 'DNA': [1805, 1954, 1969, 3492, 3632], 'Oligonucleotides': [1813], 'Technologies,': [1818], 'Inc.': [1819], 'All': [1820, 2782, 3287], 'chemicals': [1822], 'Sigma': [1828], 'unless': [1829], 'otherwise': [1830], 'specified.': [1831], 'An': [1832], 'oligo(dT)-primed': [1833], 'λgt10': [1834], 'C57B6': [1835], 'library': [1839], '(a': [1840], 'gift': [1841], 'Dr.': [1843, 2205], 'David': [1844], 'Burt,': [1845], 'University': [1846], 'Maryland)': [1848], 'screened': [1850], 'radiolabeled': [1853], '1.6-kb': [1854], 'CYP2J8': [1855, 3718, 4172], 'fragment': [1857], '(GenBankTM': [1858], 'accession': [1859], 'number': [1860], 'AF218857).': [1861], 'Nucleic': [1862], 'hybridizations': [1864], 'done': [1866], '57': [1868], '°C': [1869, 2885, 3203, 3457, 3606], '0.9': [1871], 'mNaCl': [1872], 'containing': [1873, 2614, 3089, 3165, 3404, 3461, 3568, 3685, 3817], '0.05': [1874, 2615, 3166], 'mNaH2PO4/Na2HPO4': [1875], '(pH': [1876, 2618, 3153, 3170, 3572, 3821], '7.0),': [1877], '0.5%': [1878, 3472], 'SDS,': [1879, 3473], '0.01': [1880, 2623, 3174], 'm': [1881, 2621, 3167, 3175, 3406, 3463], 'EDTA,': [1882, 3159], '5×': [1883, 3469], "Denhardt's": [1884, 3470], 'solution,': [1885, 3471], '0.1': [1887, 3475], 'mg': [1888, 3189, 3476], 'heat-denatured': [1890, 3478], 'salmon': [1891, 3479], 'sperm': [1892, 3480], 'DNA/ml.': [1893, 3481], 'Fourteen': [1894], 'duplicate': [1895, 2002], 'positive': [1896, 2003, 3690], 'clones': [1897, 2004, 2142], 'identified,': [1899], '10': [1902, 2890, 3569], 'clones,': [1903], 'selected': [1904, 2680, 2904], 'random,': [1906], 'plaque-purified': [1908], 'rescued': [1910], 'into': [1911, 2118, 2335, 2944, 3353], 'pBluescript': [1912, 1942], 'SK(+)': [1913], '(Stratagene).': [1914, 3504], 'Plasmid': [1915, 1922], 'DNAs': [1916], 'Qiagen': [1921], 'Purification': [1923], 'Kit': [1924], '(Qiagen': [1925], 'Inc.,': [1926, 1996], 'Chatsworth,': [1927], 'CA),': [1928, 2131, 3779, 4325], 'insert': [1930, 2187], 'sizes': [1931], 'determined': [1933, 2066, 2545, 3786], 'agarose': [1935, 3402, 3683], 'gel': [1936], 'electrophoresis': [1937], 'after': [1938, 2523], 'EcoRI': [1939], 'digestion.': [1940], 'The': [1941, 2084, 2111, 2319, 2346, 2876, 2936, 3482, 3526, 3610, 3676, 3723], 'inserts': [1944], 'partially': [1946, 3858], 'sequenced': [1947, 2153], 'ABI': [1950, 1958], 'model': [1951], '377': [1952], 'automated': [1953], 'sequencer': [1955], 'PRISM': [1959], 'Dye': [1960], 'Terminator': [1961], 'Cycle': [1962], 'Sequencing': [1963], 'Ready': [1964], 'Reaction': [1965, 2612, 3163, 3207], 'kit': [1966, 2127, 3522], '(PerkinElmer': [1971, 3523], 'Sciences)': [1973], 'T3/T7': [1975], 'universal': [1976], 'oligonucleotide': [1977, 2159], 'primers.': [1978], 'Nucleotide': [1979], 'sequences': [1980], 'analyzed': [1982, 2706, 2808, 3212], 'searching': [1984], 'GenBankTM': [1985], 'EMBL': [1987], 'data': [1988, 2907], 'bases': [1989], 'utilizing': [1990, 2154], 'GCG': [1991], 'software': [1992], '(Genetics': [1993], 'Computer': [1994], 'Group,': [1995], 'Madison,': [1997], 'WI).': [1998], '(clone': [2005, 2149], 'WQ24-1,': [2006], '∼1.8-kb)': [2007], 'contained': [2008, 2143], 'novel': [2010], 'sequence': [2011, 2359, 4074, 4079], 'shared': [2013], 'homology': [2014], 'several': [2016], 'rodent': [2019, 3334], 'CYP2': [2020, 4083], 'family': [2021, 4084], '(36Nelson': [2023], 'Koymans': [2025], 'Kamataki': [2027], 'Stegeman': [2029], 'J.J.': [2030], 'Feyereisen': [2031], 'R.': [2032, 2277, 2454, 2558, 2759, 3264, 4014, 4135, 4251], 'Waxman': [2033], 'Waterman': [2035], 'Gotoh': [2037], 'O.': [2038], 'Coon': [2039], 'M.J.': [2040], 'Gunsalus': [2043], 'I.C.': [2044], 'Nebert': [2045], 'D.W.': [2046], 'Pharmacogenetics.': [2047], '6:': [2049], '1-42Crossref': [2050], '(2669)': [2053], 'alignment': [2058], 'members,': [2063], 'it': [2064], 'clone': [2069, 3692], 'missing': [2071], '∼120': [2072], 'nucleotides': [2073, 3538, 3549, 3744, 3756], '5′-end': [2076], 'start': [2082], 'codon.': [2083], 'full-length': [2085], 'obtained': [2088, 3323], '5′-rapid': [2090], 'amplification': [2091, 3512], 'ends': [2094], 'Brain': [2097], 'Marathon-ReadyTM': [2098], '(CLONTECH': [2100], 'Laboratories,': [2101], 'Palo': [2102], 'Alto,': [2103], 'CA)': [2104, 2222], 'following': [2107, 3355, 3527, 3724], 'gene-specific': [2108], 'primer,': [2109, 3534, 3545, 3740, 3752], '5′-GTCTCATTGCACGCACTCTGTGTCACC-3′.': [2110], 'resulting': [2112, 2141, 2352], '∼2.0-kb': [2113], 'gel-purified,': [2116], 'cloned': [2117, 2183, 3447], 'pCRTM2.1': [2120], 'vector': [2121, 2201, 2340, 2354, 2393], 'Original': [2124], 'TA': [2125], 'Cloning': [2126], '(Invitrogen': [2128], 'Corp.,': [2129, 3776], 'Carlsbad,': [2130], 'replicated': [2133], 'DH5α-competent': [2135], 'Escherichia': [2136], 'coli.': [2137], 'Ten': [2138], 'sequences,': [2145], 'one': [2146], 'WQ2J9-7)': [2150], 'completely': [2152], 'total': [2156, 3392, 3563], '14': [2158], 'primers': [2160, 3727], '(20–25': [2161], 'nucleotides,': [2162], 'each)': [2163], 'spanned': [2165], 'entire': [2167, 2326], 'length': [2168], 'sense': [2171], 'antisense': [2173], 'strands.': [2175], 'Co-expression': [2176], 'encoded': [2180], '1.958-kb': [2184, 3448], 'WQ2J9-7': [2185, 3693], '(CYP2J9)': [2188, 3694], 'CYPOR': [2190, 2367, 2518, 2586, 3087], 'Sf9': [2192, 2478, 3077, 3082, 4161], 'insect': [2193, 4162], 'accomplished': [2196], 'pAcUW51-CYPOR': [2199, 2339], 'shuttle': [2200], '(kindly': [2202], 'provided': [2203], 'Cosette': [2206], 'Serabjit-Singh,': [2207], 'GlaxoSmithKline,': [2208], 'Research': [2209, 3380, 4101], 'Triangle': [2210], 'Park,': [2211], 'NC)': [2212], 'BaculoGold': [2215, 2397], 'Baculovirus': [2216], 'Expression': [2217], 'System': [2218, 3773], '(PharMingen,': [2219], 'San': [2220, 3777], 'Diego,': [2221, 4324], 'methods': [2224, 4121], 'similar': [2225], 'those': [2227, 2795, 3300], 'described': [2228, 2406, 2592, 2711, 2822, 2956, 3034, 3216, 3409, 3877, 4122, 4178], 'previously': [2229, 2957, 3878, 3910, 4123, 4177], '(37Wu': [2230, 2407, 2712, 3217], 'Chen': [2232, 2409, 2714, 3219, 3969, 4206], 'Murphy': [2234, 2411, 2716, 3221, 3971, 4208], 'Gabel': [2236, 2413, 2718, 3223, 3973, 4210], 'Tomer': [2238, 2272, 2415, 2449, 2720, 2754, 3225, 3259, 3883, 3975, 4009, 4041, 4130, 4212, 4246, 4278], 'K.B.': [2239, 2273, 2416, 2450, 2721, 2755, 3226, 3260, 3884, 3976, 4010, 4042, 4131, 4213, 4247, 4279], 'Foley': [2240, 2417, 2722, 3227, 3977, 4214], 'Steenbergen': [2242, 2419, 2724, 3229, 3979, 4216], 'Moomaw': [2246, 2274, 2423, 2451, 2728, 2756, 3233, 3261, 3881, 3983, 4011, 4039, 4132, 4220, 4248, 4276], 'C.R.': [2247, 2275, 2424, 2452, 2729, 2757, 3234, 3262, 3882, 3984, 4012, 4040, 4133, 4221, 4249, 4277], '1997;': [2253, 2430, 2735, 3240, 3990, 4227], '272:': [2254, 2431, 2736, 3241, 3991, 4228], '12551-12559Abstract': [2255, 2432, 2737, 3242, 3992, 4229], '(215)': [2263, 2440, 2745, 3250, 4000, 4237], '38Ma': [2266, 2443, 2748, 3253, 4003, 4240], 'Qu': [2268, 2445, 2750, 3255, 4005, 4126, 4242], 'Scarborough': [2270, 2447, 2752, 3257, 4007, 4128, 4244], 'P.E.': [2271, 2448, 2753, 3258, 4008, 4129, 4245], 'Maronpot': [2276, 2453, 2758, 3263, 4013, 4134, 4250], 'Davis': [2278, 2455, 2760, 3265, 4015, 4136, 4252], 'L.S.': [2279, 2456, 2761, 3266, 4016, 4137, 4253], '17777-17788Abstract': [2289, 2466, 2771, 3276, 4026, 4147, 4263], '(91)': [2297, 2474, 2779, 3284, 4034, 4155, 4271], '39Lee': [2300], 'Kadwell': [2302, 2595], 'S.H.': [2303, 2596], 'Kost': [2304, 2597], 'T.A.': [2305, 2598], 'Serabjit-Singh': [2306, 2599], 'Arch.': [2308, 2601], '319:': [2312, 2605], '157-167Crossref': [2313, 2606], '(94)': [2316, 2609], '(nucleotides': [2322], '130–1649)': [2323], 'coding': [2327], 'region': [2328], 'amplified': [2330], 'ligated': [2334], 'slightly': [2337], 'modified': [2338], 'NheI': [2343], 'andKpnI': [2344], 'sites.': [2345], 'orientation': [2347], 'identity': [2349], '(pAcUW51-CYPOR-CYP2J9)': [2355], 'confirmed': [2357, 3509], 'analysis.': [2360], 'construct,': [2363], 'controlled': [2369, 2381], 'p10': [2372], 'promoter,': [2373], 'whereas': [2374], 'independently': [2380], 'polyhedrin': [2384], 'promoter.': [2385], 'Cultured': [2386, 2477], 'co-transfected': [2389], 'pAcUw51-CYPOR-CYP2J9': [2392], 'linear': [2395], 'wild-type': [2396], 'viral': [2398], 'DNA,': [2399], 'viruses': [2402], 'purified': [2404, 2932, 3499, 3875], 'grown': [2480], 'spinner': [2482], 'flasks': [2483], 'density': [2486], '1.5–2': [2488], '×': [2489, 3014, 4315, 4317], '106cells/ml': [2490], 'then': [2492], 'infected': [2493, 4164], 'titer': [2496], 'CYP2J9-CYPOR': [2497], 'stock': [2500], 'presence': [2503, 3617], 'δ-aminolevulinic': [2505], 'iron': [2508], 'citrate': [2509], '(100': [2510], 'μm': [2511, 3196, 3581], 'each).': [2512], 'Cells': [2513], 'co-expressing': [2514], 'harvested': [2520], '72': [2521, 3665, 3674], 'h': [2522], 'infection,': [2524], 'washed': [2525], 'twice': [2526], 'phosphate-buffered': [2528], 'saline,': [2529], 'used': [2531, 3729], 'prepare': [2533], 'microsomal': [2534, 3192], 'fractions': [2535, 3135], 'differential': [2537, 3144], 'centrifugation': [2538, 3145], '4': [2540], '°C.': [2541, 2659, 3675], 'content': [2543], 'spectrally': [2546, 3091], 'according': [2547, 3384], 'method': [2550], 'Omura': [2552], 'Sato': [2554, 2557], '(40Omura': [2555], '1964;': [2562], '239:': [2563], '2370-2378Abstract': [2564], 'Shimadzu': [2573], 'UV-3000': [2574], 'dual-wavelength/double-beam': [2575], 'spectrophotometer': [2576], '(Shimadzu': [2577], 'Scientific': [2578], 'Instruments,': [2579], 'Columbia,': [2580], 'MD).': [2581], 'expressing': [2583, 3085], 'only': [2584], '(no': [2587], 'P450)': [2588], 'prepared': [2590, 3137, 3376, 3795, 4159, 4175], '(39Lee': [2593], 'mixtures': [2613, 3164], 'mTris-Cl': [2616], 'buffer': [2617, 3152, 3169, 3567, 3816], '7.5),': [2619, 3171], '0.15': [2620, 3622], 'KCl,': [2622, 3173, 3576], 'mMgCl2,': [2624], '8': [2625, 3177], 'mm': [2626, 2870, 3150, 3158, 3178, 3186, 3466, 3570, 3575, 3578, 3585, 3620, 3819, 3827, 3830, 3836, 3852], 'sodium': [2627, 3179, 3467, 3833], 'isocitrate,': [2628, 3180], '0.5': [2629, 3181], 'IU/ml': [2630, 3182], 'isocitrate': [2631, 3183], 'dehydrogenase,': [2632, 3184], 'CYP2J9-CYPOR-transfectedSf9': [2633], '(an': [2636], 'amount': [2637, 3736], 'corresponding': [2638, 2848, 2926, 2945, 3536, 3742, 4065], '0.1–0.2': [2640], 'nmol': [2641], 'P450/ml,': [2642], 'final': [2643, 2652, 2666, 3109, 3670], 'concentration),': [2644], '(55–56': [2648], 'μCi/μmole;': [2649], '100': [2650, 3107, 3195, 3851], 'μm,': [2651, 3012, 3108], 'concentration)': [2653, 2667, 3110], 'constantly': [2655], 'stirred': [2656], '37': [2658, 3202], 'After': [2660, 3432], 'temperature': [2661], 'equilibration,': [2662], 'NADPH': [2663], '(1': [2664], 'mm,': [2665, 3016], 'added': [2669], 'initiate': [2671], 'reaction.': [2673], 'At': [2674], 'time': [2676, 2896], 'points': [2677], '(5–20': [2678], 'min,': [2679, 3062], 'ensure': [2682], 'quantitative': [2685], 'assessment': [2686], 'rates': [2689], 'product': [2691], 'formation': [2692], 'reflect': [2693], 'initial': [2694, 2894, 3636], 'rates),': [2695], 'aliquots': [2696], 'withdrawn,': [2698], 'extracted': [2704, 3210], 'reverse-phase': [2708, 3132], 'HPLC': [2709, 2792, 2921, 2949, 3214, 3297], 'identified': [2785, 3120, 3290], 'comparing': [2787, 3292], 'their': [2788, 3293], 'reverse-': [2789, 3294], 'normal-phase': [2791, 2934, 3296], 'authentic': [2797, 3054, 3124, 3302], 'EET': [2798, 3303], 'HETE': [2800, 3305], 'standards.': [2801, 3306], 'CYP2J9-derived': [2805], 'negative': [2810], 'chemical': [2812], 'ionization': [2813], 'GC/MS': [2814], 'methane': [2816], 'reagent': [2819], '(41Clare': [2823], 'R.A.': [2824], 'Doig': [2827], 'M.V.': [2828], 'Gibson': [2829], 'G.G.': [2830], 'Chromatogr.': [2832, 3038], '562:': [2834], '237-247Crossref': [2835], '(20)': [2838], 'Briefly,': [2841], 'derivatized': [2845, 2923], '(PFB)': [2850], 'ester,': [2851], 'trimethylsilyl': [2852], 'ether,': [2853], 'injected': [2855], 'ThermoQuest': [2858], 'Trace': [2859], 'MS': [2860], 'equipped': [2861], '30-m': [2864], 'Supelco': [2865], 'SPB-5': [2866], 'capillary': [2867], 'column': [2868, 3010], '(0.32': [2869], 'inner': [2871], 'diameter,': [2872], '0.25-μm': [2873], 'film': [2874], 'thickness).': [2875], 'chromatograph': [2878], 'programmed': [2880], '150': [2882, 3826], '300': [2884], 'rate': [2888], '°C/min': [2891], 'hold': [2895], '1': [2898, 3031, 3155, 3157, 3185, 3560, 3584, 3829, 3835, 3841, 3844, 3847, 4318], 'min.': [2899, 3206, 3609], 'Both': [2900], 'full': [2901], 'scan': [2902], 'monitoring': [2906], 'collected.': [2909], 'chiral': [2911], 'analysis,': [2912, 3391], 'collected': [2918], 'eluent,': [2922], 'PFB': [2927], 'or': [2928, 4304], 'methyl': [2929], 'esters,': [2930], 'HPLC.': [2935, 3133], '11,12-EET-PFB,': [2937], '8,9-EET-PFB,': [2938], '14,15-EET-methyl': [2940], 'esters': [2941], 'resolved': [2943, 4328], 'antipodes': [2946], 'chiral-phase': [2948], 'quantified': [2951], 'scintillation': [2954], '(42Capdevila': [2958], 'Karara': [2962], 'Methods': [2966], 'Enzymol.': [2967], '206:': [2969], '441-453Crossref': [2970], '(72)': [2973], '43Hammonds': [2976], 'I.A.': [2979], 'Anal.': [2984], '1989;': [2986], '182:': [2987], '300-303Crossref': [2988], '(47)': [2991], 'Chiral': [2994], '19-HETE-methyl': [2997], 'ester': [2998], 'performed': [3000, 3073, 3454, 3558, 3614], 'naphthylated': [3002], 'derivatives': [3003], 'Pirkle': [3006], 'covalent': [3007], 'd-phenyl': [3008], 'glycine': [3009, 4312], '(5': [3011], '4.6': [3013], '250': [3015], 'Regis': [3017], 'Chemical': [3018], 'Co.,': [3019], 'Morton': [3020], 'Grove,': [3021], 'IL)': [3022], 'equilibrated': [3023], '99.75%': [3025], 'hexane,': [3026], '0.25%': [3027, 3832], 'isopropyl': [3028], 'alcohol': [3029], 'ml/min': [3032], '(44Oliw': [3035], '526:': [3040], '525-529Crossref': [3041], '(8)': [3044], 'Under': [3047], 'conditions,': [3049], 'retention': [3051], 'times': [3052], 'for': [3053, 3113, 3204, 3607, 3638, 3697, 3732], '(19R)-': [3055], '(19S)-HETEs': [3057], '76': [3059], '80': [3061, 4316], 'respectively,': [3063], 'resolution': [3066], 'factor': [3067], '0.93.': [3069], 'Control': [3070], 'studies': [3071], 'incubating': [3075], 'uninfected': [3076], 'baculovirus-infected': [3081], 'but': [3088, 3925], 'no': [3090], 'evident': [3092], 'under': [3097], 'conditions.': [3099], 'some': [3101, 3347], 'experiments,': [3102, 3348], '(55': [3105], 'μCi/μmol;': [3106], 'substituted': [3112, 3696], 'co-elution': [3122], 'hydroxyoctadecenoic': [3125], 'epoxyoctadecenoic': [3128], 'standards': [3130], 'Microsomal': [3134], 'freshly': [3139], 'brains': [3142], 'resuspended': [3147], '50': [3149, 3574, 3594, 3818], 'Tris-Cl': [3151, 3168], '7.4),': [3154, 3822], 'mmdithiothreitol,': [3156], '20%': [3161], 'glycerol.': [3162], '0.15m': [3172], 'MgCl2,': [3176, 3579, 3621], 'NADPH,': [3187], '5': [3188, 3577], 'protein/ml,': [3193], 'incubated': [3200, 3603], '30–90': [3205], 'Normal': [3307], '(lung,': [3310], 'liver,': [3312], 'spleen,': [3314], 'stomach,': [3316], 'small': [3317], 'colon,': [3319], 'testes)': [3321], 'adult': [3325], 'male': [3326], 'female': [3328], 'C57BL/6J': [3329], 'mice': [3330], 'fed': [3331], 'NIH': [3332], 'chow': [3335], '(Agway,': [3336], 'St.': [3337], 'Mary,': [3338], 'OH)ad': [3339], 'libitum': [3340], 'sacrificed': [3342], 'lethal': [3344], 'CO2inhalation.': [3345], 'subdivided': [3352], 'anatomic': [3356], 'conventional': [3359], 'morphologic': [3360], 'criteria': [3361], 'follows:': [3363], 'cerebellum,': [3364, 3803], 'cortex,': [3366, 3805], 'hippocampus,': [3367, 3806], 'striatum,': [3368, 3807], 'hypothalamus,': [3369, 3808], 'midbrain,': [3370, 3809], 'brainstem,': [3371], 'pituitary.': [3373], 'TRIreagent': [3378], '(Molecular': [3379], 'Center,': [3381], 'Cincinnati,': [3382], 'OH)': [3383], "manufacturer's": [3387], 'instructions.': [3388], '(20': [3394], 'μg)': [3395], 'denatured': [3397], 'electrophoresed': [3399, 3680, 4308], '1.2%': [3401, 3682], 'gels': [3403, 3684, 3765, 4313], '2.2': [3405], 'formaldehyde': [3407], '(45Maniatis': [3410], 'Sambrook': [3412], 'Fritsch': [3414], 'Molecular': [3416], 'Cloning:': [3417], 'Laboratory': [3419], 'Manual.': [3420], '2nd': [3421], 'Ed.': [3422], 'Cold': [3423, 3427], 'Spring': [3424, 3428], 'Harbor': [3425], 'Laboratory,': [3426], 'Harbor,': [3429], 'NY1989Google': [3430], 'capillary-pressure': [3433], 'transfer': [3434, 4331], 'Hybond-N+': [3436], 'membranes': [3437], '(Amersham': [3438, 3495], 'Pharmacia': [3439, 3496], 'Biotech),': [3440], 'blots': [3442], 'hybridized': [3444], 'insert.': [3451], 'Hybridizations': [3452], '42': [3456, 3605], '50%': [3459], 'formamide': [3460], '0.7': [3462], 'NaCl,': [3464, 3828], '70': [3465], 'citrate,': [3468], 'probe': [3484], 'labeled': [3486], '[α-32P]dATP': [3488], 'MegaprimeTM': [3491], 'labeling': [3493], 'system': [3494], 'Biotech)': [3497], 'G-50': [3501], 'Sephadex': [3502], 'columns': [3503], 'blot': [3506], 'results': [3507], 'reverse-transcribed': [3514], 'RNAs': [3516], 'GeneAmp®': [3519], 'Sciences).': [3525], 'sequence-specific': [3529, 3726], 'oligonucleotides': [3530], 'used:': [3532], 'forward': [3533, 3739], '5′-CAACCTAACTGCACTGCACAG-3′,': [3535], '1403–1423': [3539], 'cDNA;': [3543, 3750], 'reverse': [3544, 3601, 3625, 3751], '5′-GGCTTTCTACTTACTGAACCC-3′,': [3546], 'complementary': [3547, 3754], '1834–1854': [3550], 'cDNA.': [3554, 3762], 'Reverse': [3555], 'transcription': [3556], 'μg': [3561], 'Tris-HCl': [3571, 3820], '8.3),': [3573], '2.5': [3580, 3628], 'random': [3582], 'hexamers,': [3583], 'each': [3586], 'dGTP,': [3588], 'dATP,': [3589], 'dTTP,': [3590], 'dCTP,': [3592], 'units': [3595, 3629], 'Moloney': [3597], 'murine': [3598], 'leukemia': [3599], 'virus': [3600], 'transcriptase': [3602], '15': [3608], 'amplifications': [3612], '2': [3619], 'μmforward': [3623], 'primers,': [3626, 3710], 'polymerase.': [3633], 'Following': [3634, 3763], 'incubation': [3637, 3672], '120': [3639], 's': [3640, 3652, 3657, 3663], '95': [3642, 3654], '°C,': [3643, 3655, 3660, 3666], 'samples': [3644], 'subjected': [3646], '30': [3648], 'cycles': [3649], '25': [3651], '45': [3656, 3662], '64': [3659], 'followed': [3667], '7-min': [3671], 'ethidium': [3686], 'bromide.': [3687], 'As': [3688], 'control,': [3691], 'first': [3699], 'strand': [3700], 'products.': [3701], 'Negative': [3702], 'controls': [3703], 'included': [3704], 'omission': [3705, 3708], 'RNA,': [3707], 'use': [3712], 'CYP2J5,': [3714, 3921, 4169], 'CYP2J6,': [3715, 3922], 'CYP2J7,': [3716], 'cDNAs': [3719], 'template.': [3722], 'β-actin': [3725, 3749, 3761, 3791], 'quality': [3734], 'RNA:': [3738], '5′-GAGCTATGAGCTGCCTGACG-3′,': [3741], '776–795': [3745], '5′-AGCACTTGCGGTGCACGATG-3′,': [3753], '1166–1185': [3757], 'electrophoresis,': [3764], 'scanned': [3767], 'ChemiImager': [3770], '4000': [3771], 'Imaging': [3772], '(Alpha': [3774], 'Innotech': [3775], 'Leandro,': [3778], 'relative': [3781], 'normalization': [3788], 'signal.': [3792], 'Lysates': [3793], 'frozen': [3797], '(3-day': [3799], '7-month': [3801], 'postnatal)': [3802], 'brainstem': [3811], 'homogenization': [3813], '1%': [3823], 'Triton': [3824], 'X-100,': [3825], 'EGTA,': [3831], 'deoxycholate,': [3834], 'NaF,': [3837], '0.25': [3838], 'mphenylmethylsulfonyl': [3839], 'fluoride,': [3840], 'mg/ml': [3842, 3845, 3848], 'leupeptin,': [3843], 'aprotinin,': [3846], 'pepstatin,': [3849], 'Na3VO4.': [3853], 'Polyclonal': [3854, 4105], 'antibodies': [3855, 4106], 'purified,': [3859], '(anti-CYP2J2': [3864], 'IgG)': [3865, 4112], 'Zealand': [3870, 4117], 'White': [3871, 4118], 'rabbits': [3872, 4119], 'affinity': [3874], '(46Wu': [3879], '3460-3468Abstract': [3894, 4052, 4289], '(426)': [3902, 4060, 4297], 'This': [3905, 4086], 'immunoreact': [3912], '(including': [3918], 'CYP2J2,': [3919, 4167], 'CYP2J3,': [3920, 4168], 'CYP2J8)': [3924], 'does': [3926], 'not': [3927], 'cross-react': [3928], 'CYP2A,': [3934], '37Wu': [3967, 4204], '46Wu': [4037, 4274], 'amino': [4067], '346–357': [4069], 'deduced': [4072], 'designed': [4076], 'based': [4077], 'upon': [4078], 'alignments': [4080], 'synthesized,': [4089], 'HPLC-purified,': [4090], 'coupled': [4092], 'keyhole': [4094], 'limpet': [4095], 'hemocyanin': [4096], 'enhance': [4098], 'antigenicity': [4099], 'Genetics': [4102], '(Huntsville,': [4103], 'AL).': [4104], '(anti-CYP2J9pep2': [4111], '(38Ma': [4124], 'CYP2J6': [4170], 'baculoviruses': [4173], 'immunoblotting,': [4301], 'lysates': [4303], '8–16%': [4310], 'Tris': [4311], '(80': [4314], 'mm)': [4319], 'NOVEX': [4322], '(San': [4323], 'proteins': [4329]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2168115819', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T14:43:58.116536', 'created_date': '2016-06-24'}