Publication Information

{'id': 'https://openalex.org/W2166822294', 'doi': 'https://doi.org/10.1016/0041-008x(89)90281-0', 'title': 'A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: In vitro toxicity to precursor cells and microstromal environment', 'display_name': 'A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: In vitro toxicity to precursor cells and microstromal environment', 'publication_year': 1989, 'publication_date': '1989-11-01', 'ids': {'openalex': 'https://openalex.org/W2166822294', 'doi': 'https://doi.org/10.1016/0041-008x(89)90281-0', 'mag': '2166822294', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2554533'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0041-008x(89)90281-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42307217', 'display_name': 'Toxicology and Applied Pharmacology', 'issn_l': '0041-008X', 'issn': ['0041-008X', '1096-0333'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113533052', 'display_name': 'Michael I. Luster', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Michael I. Luster', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042887827', 'display_name': 'Dori R. Germolec', 'orcid': 'https://orcid.org/0000-0003-4072-1956'}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dori R. Germolec', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110893970', 'display_name': 'Kimber L. White', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72019824', 'display_name': 'Virginia Commonwealth University Medical Center', 'ror': 'https://ror.org/057xmsr27', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I72019824']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kimber L. White', 'raw_affiliation_strings': ['Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA', 'institution_ids': ['https://openalex.org/I72019824']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113600604', 'display_name': 'Bruce A. Fuchs', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72019824', 'display_name': 'Virginia Commonwealth University Medical Center', 'ror': 'https://ror.org/057xmsr27', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I72019824']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Bruce A. Fuchs', 'raw_affiliation_strings': ['Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA', 'institution_ids': ['https://openalex.org/I72019824']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024777470', 'display_name': 'Madeline Fort', 'orcid': 'https://orcid.org/0000-0003-2261-476X'}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Madeline M. Fort', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001262482', 'display_name': 'Joseph E. Tomaszewski', 'orcid': 'https://orcid.org/0000-0003-2009-203X'}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joseph E. Tomaszewski', 'raw_affiliation_strings': ['Toxicology Branch, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Rockville, Maryland 20205 USA'], 'affiliations': [{'raw_affiliation_string': 'Toxicology Branch, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, Rockville, Maryland 20205 USA', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110090483', 'display_name': 'Morrow B. Thompson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Morrow Thompson', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044660168', 'display_name': 'Patricia Blair', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Patricia C. Blair', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035875393', 'display_name': 'J. A. McCay', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72019824', 'display_name': 'Virginia Commonwealth University Medical Center', 'ror': 'https://ror.org/057xmsr27', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I72019824']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J.Ann McCay', 'raw_affiliation_strings': ['Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA', 'institution_ids': ['https://openalex.org/I72019824']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003072947', 'display_name': 'Albert E. Munson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72019824', 'display_name': 'Virginia Commonwealth University Medical Center', 'ror': 'https://ror.org/057xmsr27', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I72019824']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Albert E. Munson', 'raw_affiliation_strings': ['Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, Virginia 23298 USA', 'institution_ids': ['https://openalex.org/I72019824']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109103726', 'display_name': 'Gary J. Rosenthal', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210095140', 'display_name': 'National Institute of Environmental Health Sciences', 'ror': 'https://ror.org/00j4k1h63', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210095140']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gary J. Rosenthal', 'raw_affiliation_strings': ['Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA'], 'affiliations': [{'raw_affiliation_string': 'Immunotoxicology Group, Systemic Toxicology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}, {'raw_affiliation_string': 'Chemical Pathology Branch, National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709 USA', 'institution_ids': ['https://openalex.org/I4210095140']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5113533052'], 'corresponding_institution_ids': ['https://openalex.org/I4210095140'], 'apc_list': {'value': 3920, 'currency': 'USD', 'value_usd': 3920, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.888, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 37, 'citation_normalized_percentile': {'value': 0.760458, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '101', 'issue': '2', 'first_page': '328', 'last_page': '339'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11725', 'display_name': 'Immunodeficiency and Autoimmune Disorders', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11725', 'display_name': 'Immunodeficiency and Autoimmune Disorders', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10950', 'display_name': 'Acute Lymphoblastic Leukemia research', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nucleoside-analogue', 'display_name': 'Nucleoside analogue', 'score': 0.6019272}], 'concepts': [{'id': 'https://openalex.org/C2780216070', 'wikidata': 'https://www.wikidata.org/wiki/Q198504', 'display_name': 'Zidovudine', 'level': 4, 'score': 0.81419265}, {'id': 'https://openalex.org/C2777333352', 'wikidata': 'https://www.wikidata.org/wiki/Q2689559', 'display_name': 'Nucleoside analogue', 'level': 3, 'score': 0.6019272}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.5922556}, {'id': 'https://openalex.org/C2780007613', 'wikidata': 'https://www.wikidata.org/wiki/Q546523', 'display_name': 'Bone marrow', 'level': 2, 'score': 0.5643339}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.55978054}, {'id': 'https://openalex.org/C2776543447', 'wikidata': 'https://www.wikidata.org/wiki/Q28734', 'display_name': 'Nucleoside', 'level': 2, 'score': 0.5488714}, {'id': 'https://openalex.org/C109159458', 'wikidata': 'https://www.wikidata.org/wiki/Q919283', 'display_name': 'Haematopoiesis', 'level': 3, 'score': 0.52802956}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.49029544}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.48090935}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.45270723}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44444752}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.4161695}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.32575616}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.28351593}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.108967364}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10709739}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.07862356}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.054727554}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000998', 'descriptor_name': 'Antiviral Agents', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D016048', 'descriptor_name': 'Dideoxyadenosine', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D006410', 'descriptor_name': 'Hematopoiesis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D016047', 'descriptor_name': 'Zalcitabine', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D000163', 'descriptor_name': 'Acquired Immunodeficiency Syndrome', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D000163', 'descriptor_name': 'Acquired Immunodeficiency Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000937', 'descriptor_name': 'Antigen-Antibody Reactions', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D000937', 'descriptor_name': 'Antigen-Antibody Reactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000998', 'descriptor_name': 'Antiviral Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001853', 'descriptor_name': 'Bone Marrow', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001853', 'descriptor_name': 'Bone Marrow', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001853', 'descriptor_name': 'Bone Marrow', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016048', 'descriptor_name': 'Dideoxyadenosine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D016048', 'descriptor_name': 'Dideoxyadenosine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006678', 'descriptor_name': 'HIV', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006678', 'descriptor_name': 'HIV', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D006678', 'descriptor_name': 'HIV', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006410', 'descriptor_name': 'Hematopoiesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007111', 'descriptor_name': 'Immunity, Cellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007111', 'descriptor_name': 'Immunity, Cellular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013234', 'descriptor_name': 'Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013234', 'descriptor_name': 'Stem Cells', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D016047', 'descriptor_name': 'Zalcitabine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016047', 'descriptor_name': 'Zalcitabine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0041-008x(89)90281-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42307217', 'display_name': 'Toxicology and Applied Pharmacology', 'issn_l': '0041-008X', 'issn': ['0041-008X', '1096-0333'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2554533', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.86}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 32, 'referenced_works': ['https://openalex.org/W1485519622', 'https://openalex.org/W1496932821', 'https://openalex.org/W1513286425', 'https://openalex.org/W1517632611', 'https://openalex.org/W1574606979', 'https://openalex.org/W1575069311', 'https://openalex.org/W1945038306', 'https://openalex.org/W1963839080', 'https://openalex.org/W1983559242', 'https://openalex.org/W2022059729', 'https://openalex.org/W2042491102', 'https://openalex.org/W2051014475', 'https://openalex.org/W2081164125', 'https://openalex.org/W2082619145', 'https://openalex.org/W2086186867', 'https://openalex.org/W2093943927', 'https://openalex.org/W2102495005', 'https://openalex.org/W2102973576', 'https://openalex.org/W2139727555', 'https://openalex.org/W2143773220', 'https://openalex.org/W2171775661', 'https://openalex.org/W2200542405', 'https://openalex.org/W2256656933', 'https://openalex.org/W2333399282', 'https://openalex.org/W2336515255', 'https://openalex.org/W2413454989', 'https://openalex.org/W2414356660', 'https://openalex.org/W2416164993', 'https://openalex.org/W2474650552', 'https://openalex.org/W2474703189', 'https://openalex.org/W2784065401', 'https://openalex.org/W4256221661'], 'related_works': ['https://openalex.org/W4245003655', 'https://openalex.org/W2364077983', 'https://openalex.org/W2337832730', 'https://openalex.org/W2319277371', 'https://openalex.org/W2100861792', 'https://openalex.org/W2089583823', 'https://openalex.org/W2032476929', 'https://openalex.org/W2009204607', 'https://openalex.org/W2005511705', 'https://openalex.org/W1028162192'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2166822294', 'counts_by_year': [{'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-07T21:57:26.558080', 'created_date': '2016-06-24'}