Publication Information

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'sleep,': [109, 185, 1874], 'leading': [110], 'a': [112, 235, 298, 521, 567, 613, 699, 808, 953, 1007, 1060, 1076, 1086, 1095, 1137, 1183, 1225, 1338, 1409, 1416, 1436, 1479, 1544, 1552, 1719, 1868, 2242, 2344, 2597, 2822, 3137, 3173, 3654, 3987], 'fall': [113, 1591], 'in': [114, 204, 216, 220, 226, 263, 323, 332, 399, 407, 437, 446, 492, 550, 570, 603, 654, 673, 690, 701, 729, 776, 901, 952, 983, 1012, 1079, 1084, 1126, 1132, 1220, 1362, 1390, 1426, 1458, 1461, 1507, 1517, 1547, 1566, 1627, 1669, 1703, 1722, 1749, 1798, 1810, 1898, 1904, 1912, 1916, 1933, 2005, 2040, 2066, 2117, 2139, 2192, 2217, 2236, 2275, 2282, 2308, 2382, 2438, 2466, 2536, 2671, 2701, 2808, 2834, 2866, 2871, 2888, 2966, 2994, 3040, 3069, 3073, 3093, 3131, 3166, 3208, 3242, 3261, 3289, 3386, 3413, 3489, 3540, 3580, 3613, 3671, 3747, 3792, 3992, 3998, 4037, 4086], 'oxygen': [115, 354, 584, 628, 1165, 1172, 1487, 1880], 'saturation': [116, 1488], '≥4%': [118], 'sleep': [120, 130, 155, 1603, 1835, 1893, 2119, 2143, 2196, 2212, 2384, 2459, 2538, 2802, 2970, 3129, 3210, 3240, 3292, 3417, 3493, 3538, 3660, 3751], 'fragmentation.': [121], 'Sleep': [122, 232, 252, 745, 803, 2003, 2400, 2495, 2604, 2640, 2676, 2697, 2831, 2868, 2884, 2892, 2909, 3035, 3095, 3098, 3176, 3380, 3420, 3571, 3605, 3707, 3762, 3785, 3875, 3996, 4041, 4084], 'can': [124, 377], 'be': [125, 339, 379, 443, 532, 590, 696, 709, 740, 788, 1213, 1308, 1430, 1510, 1577, 1585, 1600, 1611, 1689, 1896, 1931, 2286, 2295, 2312, 2328], 'central': [126, 150, 229, 2433, 2628, 3537], 'obstructive.': [128], 'Central': [129, 2883, 4083], '(CSA)': [132], 'characterized': [134, 503], 'apneas': [136, 1872, 2629], 'secondary': [137], 'diminution': [139], 'thoraco-abdominal': [143], 'movements': [145], '(due': [146, 1174], 'dysfunction': [148, 1320, 3746], 'control': [152, 461], 'mechanisms).': [153], 'Obstructive': [154, 2458, 2675, 2696, 2867, 2881, 2908, 3034, 3094, 3604, 3706, 3874, 4040], '(OSA)': [157], 'caused': [159], 'upper': [161, 1255], 'airway': [162, 484, 1243, 2061, 2186, 2209, 3759], 'collapse': [163, 1252], 'inspiration': [165], 'accompanied': [168, 581], 'strenuous': [170], 'breathing': [171, 303, 314, 813, 1375, 1983, 2095, 2159, 3165], 'efforts.': [172], 'When': [173], '>5': [176], 'hypopnea': [181, 2589], 'per': [182], 'hour': [183], 'OSA': [186, 775, 796, 854, 909, 956, 982, 996, 1011, 1025, 1043, 1143, 1274, 1283, 1315, 1334, 1345, 1359, 1391, 1425, 1459, 1474, 1508, 1520, 1574, 1588, 1609, 1664, 1670, 1684, 1702, 1755, 1813, 1841, 1860, 1927], 'relatively': [188], 'common,': [189], 'affecting': [190], '24%': [191], '9%': [193], 'middle-aged': [195, 1985], 'men': [196], 'women,': [198], 'respectively.1': [199], 'CSA': [200, 262, 295, 359, 371, 398, 406, 440, 468, 480, 501, 528, 548, 552, 574, 607, 658, 694, 706, 728, 1862, 1929, 2736], 'primarily': [202], 'seen': [203], 'patients': [205, 265, 447, 499, 605, 656, 692, 731, 1013, 1133, 1363, 1460, 1567, 1589, 1679, 1750, 1811, 1899, 1917, 1935, 2009, 2069, 2140, 2193, 2218, 2467, 2540, 2811, 2967, 3132, 3167, 3290, 3414, 3490, 3541, 3748], 'with': [206, 228, 249, 304, 329, 360, 412, 434, 448, 457, 500, 566, 606, 612, 657, 665, 682, 693, 732, 750, 864, 908, 955, 972, 1014, 1101, 1134, 1150, 1222, 1224, 1277, 1344, 1352, 1364, 1396, 1432, 1490, 1519, 1568, 1613, 1680, 1691, 1718, 1751, 1781, 1787, 1801, 1812, 1821, 1900, 1918, 2010, 2070, 2141, 2194, 2219, 2468, 2541, 2601, 2674, 2805, 2968, 3133, 3168, 3291, 3415, 3491, 3536, 3542, 3607, 3712, 3749, 3877], 'congestive': [207, 3546], 'heart': [208, 273, 475, 758, 760, 985, 1302, 1467, 1637, 1640, 2012, 2042, 2067, 2220, 3547], 'failure': [209, 274, 2068], '(CHF),': [210], 'although': [211, 1619, 1850], 'it': [212, 367, 386, 454, 1367, 1419, 1674, 3936], 'occasionally': [213], 'may': [214, 316, 441, 469, 487, 529, 708, 726, 895, 1073, 1144, 1186, 1199, 1245, 1316, 1335, 1384, 1429, 1532, 1610, 1725], 'occur': [215, 1626], 'healthy': [217], 'normal': [218], 'subjects,': [219], 'people': [221], 'at': [222, 287, 814, 964], 'high': [223, 243, 1008, 1167], 'altitudes,': [224], 'association': [227, 248, 357, 794, 810, 825, 1221, 1518, 1833, 2092], 'neural': [230, 2115, 3244], 'lesions.': [231], 'constitutes': [234], 'major': [236], 'public': [237], 'health': [238], 'problem': [239], 'because': [240], 'its': [242, 246, 325, 1291, 2337], 'prevalence': [244, 260, 523, 1009, 1226, 1357], 'emerging': [247], 'cardiovascular': [250, 752, 1784, 1838, 1846, 2064, 2161], 'morbidity.Central': [251], 'ApneaCSA': [253], 'especially': [255], 'relevant': [256], 'CHF.': [258, 395, 438, 493, 538, 1313, 1752], 'The': [259, 539, 667, 801, 1329, 1381, 1537, 1979, 2392, 2425, 2859, 3031, 3047, 3781], 'CHF': [264, 333, 361, 374, 400, 408, 498, 545, 555, 562, 604, 655, 691, 1287, 1332, 1934], 'dependent': [267], 'on': [268, 321, 642, 1293, 1658, 1882, 2063, 2189, 2211, 2321, 2432, 2508, 2812, 3037, 3128, 3163, 3204, 3486, 3709, 3787], 'various': [269], 'factors,': [270, 345, 832, 1273], 'such': [271, 346, 623, 833, 1163, 1634, 1645], 'etiology,': [275], 'gender,': [276, 842], 'age,': [277, 841], 'ejection': [278, 350, 509, 601, 679, 1740], 'fraction,': [279, 510], 'hemodynamic': [281, 714], 'status,': [282], 'has': [284, 362, 596, 609, 747, 1216, 1756], 'been': [285, 363, 597, 610, 631, 748, 1046, 1124, 1218, 1758], 'estimated': [286], '40%': [288], '60%.2,3': [290], 'Cheyne-Stokes': [291, 2038, 2073], 'respiration': [292, 946, 2039, 3535], 'occurs': [293], 'distinct': [299], 'pattern': [300], 'periodic': [302], 'alternating': [305], 'crescendo-decrescendo': [306], 'sequences': [307], 'hyperventilation': [309, 3483], '(ie,': [312, 1715], 'complete': [313], 'cessation).CSA': [315], 'have': [317, 630, 911, 1044, 1122, 1444, 1478], 'an': [318, 389, 533, 1027, 1067, 1207, 1278, 1421, 1832, 2232, 2276], 'important': [319, 1309, 1422], 'influence': [320], 'prognosis,': [322, 383], 'that': [324, 405, 467, 544, 722, 1088, 1153, 1383, 1424, 1496, 1608, 1678], 'presence': [326, 818, 1447], 'associated': [328, 433, 456, 565, 611, 749, 1276, 1431, 1612, 1717], 'increased': [330, 413, 463, 511, 678, 869, 914, 1068, 1119, 1170, 1178, 1242, 1248, 1279, 1361, 1406, 1433], 'mortality': [331, 1434], 'patients.3': [334], 'This': [335, 824, 2347], 'effect': [336], 'appears': [337], 'independent': [340, 827, 1028, 1269], 'other': [342, 496, 829, 1271, 1631, 1845], 'known': [343, 830, 1306], 'risk': [344, 831, 1069, 1260, 1272, 1280, 1310, 1387, 1763], 'left': [348, 450, 512, 1738], 'ventricular': [349, 451, 513, 1319, 1326, 1456, 1535, 1617, 1739, 2215], 'fraction': [351, 602, 1741], 'peak': [353], 'consumption.Although': [355], 'recognized': [364], 'decades,': [366], 'unclear': [369], 'whether': [370, 385, 1696], 'directly': [372], 'affects': [373], 'pathophysiology': [375], 'therefore': [378, 1336], 'causally': [380], 'linked': [381, 999], 'rather': [388], 'index': [390, 534, 1888, 2590], 'severity': [393, 636], 'Evidence': [396, 3882], 'implicating': [397, 774], 'progression': [401], 'includes': [402], 'fact': [404], 'associated,': [410], 'first,': [411], 'sympathetic': [414, 866, 879, 902, 942, 1168, 1294], 'nerve': [415, 943], 'activity,': [416, 1169], 'higher': [417, 522, 882], 'urinary': [418], 'plasma': [420, 1105], 'norepinephrine': [421], 'concentration,': [422], 'perhaps': [424, 738], 'elevated': [425, 515, 1083, 1104, 1504], 'endothelin.': [426], 'Elevated': [427, 2136], 'catecholamine': [428], 'endothelin': [430], 'levels': [431, 1106], 'are': [432, 502, 645, 855, 1305, 1521, 1622, 1790, 1937, 2240, 2249, 2259, 2264, 2272, 2279, 2299], 'poorer': [435], 'prognosis': [436, 644], 'Second,': [439], 'also': [442, 531, 677, 739, 896, 910, 1074, 1123, 1200, 1217, 1606, 1757], 'highly': [444], 'prevalent': [445], 'asymptomatic': [449], 'dysfunction,': [452, 913], 'where': [453], 'impaired': [458], 'cardiac': [459, 464, 525, 763, 1148, 1171, 1349, 1632, 1747, 1920], 'autonomic': [460, 3745], 'arrhythmias,': [465, 764, 1923], 'suggesting': [466], 'precede': [470], 'development': [472, 1002], 'overt': [474], 'failure.': [476, 2043, 2221], 'Third,': [477], 'prevention': [478], 'continuous': [482, 2059, 2184, 2207, 3757], 'positive': [483, 2060, 2185, 2208, 3758], 'pressure': [485, 871, 884, 950, 1800, 2062, 2187, 2191, 2210, 2579, 3760], '(CPAP)': [486], 'contribute': [488, 897, 1187, 1377, 2583], 'improved': [490, 743], 'outcome': [491], 'On': [494], 'hand,': [497], 'lower': [505, 917, 1484], 'exercise': [506], 'capacity': [507], 'volumes,': [514], 'pulmonary': [516, 766, 1451, 1472, 1493, 1505, 1731], 'capillary': [517], 'wedge': [518], 'pressure,': [519, 1914], 'arrhythmias.': [526], 'Therefore,': [527, 1560], 'indeed': [530], 'severe': [537, 583, 1683], 'most': [540, 754, 1513], 'likely': [541, 1624], 'scenario': [542], 'predisposes': [546], 'and,': [549, 1579], 'turn,': [551], 'contributes': [553], 'progression.TreatmentHemodynamic': [556], 'improvement': [557], 'after': [558, 2637, 2999], 'pharmacological': [559, 577], 'therapy': [560, 578, 595, 1563, 1583, 1789], 'often': [564, 1155, 1662], 'significant': [568, 671, 1720, 1892], 'decrease': [569, 634, 700, 727, 1746], 'CSA.': [571], 'However,': [572, 1773], 'persistent': [573], 'despite': [575], 'optimal': [576], '(especially': [579], 'if': [580, 1580], 'desaturation': [585, 1881], 'refractory': [587, 1901], 'CHF)': [588], 'should': [589, 1575, 1584, 1688, 1885, 1895, 1930, 2229, 2285, 2327, 3938], 'treated': [591, 659, 664, 1690], 'aggressively.': [593], 'CPAP': [594, 676, 689, 1582, 1713, 1788, 1809, 2398], 'found': [598], 'improve': [600, 1737], 'tendency': [614], 'enhanced': [616], 'transplant-free': [617], 'survival': [618, 653], '(Figure': [619, 872, 1728], '1).4': [620], 'Other': [621], 'therapies,': [622], 'theophylline': [625], 'nocturnal': [627, 1147, 1569, 1734, 1910, 1919, 1922, 2037, 2395, 3126], 'supplementation,': [629], 'shown': [632, 1759], 'CSA,': [638], 'but': [639, 1366, 2632], 'their': [640, 2016], 'effects': [641, 715, 852, 1041, 1292, 2426, 3196], 'long-term': [643, 1438], 'not': [646, 663, 670, 1045, 1698, 2241, 2260, 2273, 2280, 2633], 'known.': [647], 'Download': [648, 927, 1793], 'figureDownload': [649, 928, 1794], 'PowerPointFigure': [650, 929, 1795], '1.': [651], 'Transplant-free': [652], '(and': [660, 1453], 'compliant)': [661], 'CPAP.': [666, 717, 1672], 'difference': [668], 'was': [669, 826], '(P=0.1)': [672], 'intention-to-treat': [674], 'analysis.': [675], 'fraction.': [680], 'Reprinted': [681, 971, 1820], 'permission': [683, 973, 1822], 'from': [684, 974, 1823, 3230, 3883], 'reference': [685, 975, 1824], '4.The': [686], 'efficacy': [687], 'might': [695, 737, 874], 'related': [697, 741], 'obstructive': [703, 2118, 2142, 2195, 2383, 2537, 2969, 3209, 3416, 3492, 3750], 'component': [704], 'accompanying': [705], 'due': [710], 'some': [712, 1470, 1497], 'direct': [713, 1077], 'An': [718, 3496], 'intriguing': [719, 1049], 'finding': [720, 1087], 'overdrive': [723], 'atrial': [724, 3932], 'pacing': [725], 'selected': [730], 'symptomatic': [733], 'sinus': [734, 1522], 'bradycardia': [735], 'hemodynamics.Obstructive': [744], 'ApneaOSA': [746], 'several': [751, 1019, 1111], 'diseases,': [753, 1839, 1847], 'notably': [755], 'hypertension,': [756, 772, 836, 1299, 1494, 1902], 'ischemic': [757, 984, 1193, 1301, 1636, 2635, 2638], 'disease,': [759, 1017, 1142, 1303, 2471], 'failure,': [761, 3548], 'stroke,': [762, 1365, 2639], 'hypertension.': [767, 1414, 1843, 2097], 'With': [768, 4000, 4028, 4039, 4088], 'exception': [770], 'evidence': [773, 790, 991, 1117, 1130, 1830, 1878], 'these': [777, 1192, 1540], 'disease': [778, 986, 1638], 'conditions': [779], 'presently': [781, 1791], 'circumstantial,': [782], 'cause-effect': [784], 'relationships': [785], 'remain': [786], 'proven.HypertensionThe': [789], 'supporting': [791], 'causal': [793], 'between': [795, 811, 1834, 2093, 3527], 'hypertension': [798, 820, 1452], 'compelling.': [800], 'Wisconsin': [802], 'Cohort': [804], 'Study': [805], 'prospectively': [806], 'demonstrated': [807], 'dose-response': [809], 'sleep-disordered': [812, 1982, 2094, 3164], 'baseline': [815, 835], '4': [821], 'years': [822], 'later.5': [823], 'body': [837, 1481], 'mass': [838, 1482], 'habitus,': [840], 'alcohol': [844], 'cigarette': [846], 'use.The': [847], 'mechanisms': [848, 1037, 1198, 2116], 'underlying': [849], 'hypertensive': [851, 1473], 'multifactorial.': [856], 'Nocturnal': [857, 2625, 2992], 'chemoreflex': [858], 'activation': [859, 867, 894], 'hypoxia': [861], 'hypercapnia,': [863], 'consequent': [865, 1241], 'blood': [870, 883, 905, 949, 1393, 1799, 1913, 2190, 2578], '2),6': [873], 'carry': [875], 'over': [876], 'into': [877], 'excessive': [878], 'activity': [880, 903, 944], 'even': [885, 1454, 1596], 'daytime': [887, 899, 1450, 1485, 1597, 1686, 1707, 1771, 1875], 'normoxia.': [888], 'Chemoreceptor': [889], 'resetting': [890], 'tonic': [892], 'chemoreceptor': [893], 'increases': [900], 'pressure.': [906, 1819], 'Patients': [907, 2673, 2732, 3041, 3999, 4038, 4087], 'endothelial': [912, 1297], 'endothelin,': [915, 1296], 'nitric': [918], 'oxide': [919], 'levels,': [920], 'all': [921, 1529], 'which': [923, 1304, 1531], 'would': [924, 1234], 'potentiate': [925, 1317], 'vasoconstriction.': [926], '2.': [930], 'Recordings': [931], 'electrooculogram': [934], '(EOG),': [935], 'electroencephalogram': [936], '(EEG),': [937], 'electromyogram': [938], '(EMG),': [939], 'electrocardiogram': [940], '(EKG),': [941], '(SNA),': [945], '(RESP),': [947], '(BP)': [951], 'patient': [954], 'rapid': [958, 3200], 'eye': [959, 3201], 'movement': [960, 3202], 'sleep.': [961], 'BP': [962], 'surges': [963], 'end': [966, 1785], 'apneic': [969], 'periods.': [970], '6.Ischemic': [976], 'Heart': [977, 2863, 3045, 3070, 3259, 3264, 3406, 3576, 3584, 3710, 4001, 4089, 4117], 'DiseaseThe': [978], 'clinical': [979, 1417, 2827], 'importance': [980], 'twofold.': [988], 'First,': [989], 'epidemiological': [990, 1265], 'supports': [992, 1089], 'concept': [994], 'being': [997], 'etiologically': [998], 'atherosclerosis.': [1004], 'There': [1005], 'coronary': [1015, 1031, 1071, 1140, 1203, 1209, 2461], 'artery': [1016, 1032, 1141], 'case-control': [1020], 'prospective': [1022], 'studies': [1023, 1443], 'suggest': [1024, 1267, 1607], 'predictor': [1029], 'disease.': [1033, 1468, 2162], 'Although': [1034, 1673], 'exact': [1036], 'any': [1039], 'atherogenic': [1040], 'established,': [1047], 'one': [1048], 'possibility': [1050], 'involvement': [1053], 'inflammatory': [1055], 'processes.': [1056], 'C-reactive': [1057, 2137], 'protein': [1058, 2138], '(CRP),': [1059], 'biomarker': [1061], 'systemic': [1063, 1179, 1727], 'inflammation': [1064, 1093], 'events,': [1072], 'play': [1075], 'role': [1078, 1091, 2393], 'atherogenesis.': [1080, 1099], 'CRP': [1081], 'OSA,7': [1085], 'mechanism': [1096, 1538], 'OSA-related': [1098, 1161], 'Consistent': [1100], 'hypothesis,': [1103], 'cell': [1108], 'expression': [1109], 'adhesion': [1112], 'molecules,': [1113], 'well': [1115], 'oxidative': [1120], 'stress,': [1121], 'noted': [1125], 'OSA.Second,': [1127], 'there': [1128], 'that,': [1131, 1268], 'without': [1136, 1492, 1907, 2072], 'history': [1138, 1869], 'trigger': [1145], 'acute': [1146, 1208, 1318, 2542, 2809], 'ischemia': [1149], 'ST-segment': [1151, 1735], 'depression': [1152], 'resistant': [1156], 'traditional': [1158], 'therapy.': [1159], 'Several': [1160], 'mechanisms,': [1162], 'desaturation,': [1166], 'demand': [1173], 'tachycardia': [1176], 'vascular': [1180], 'resistance),': [1181], 'prothrombotic': [1184, 1410], 'state,': [1185, 1411], 'onset': [1190], 'episodes.': [1194], 'Whether': [1195], 'same': [1197], 'lead': [1201, 1246, 1533], 'plaque': [1204], 'rupture': [1205], 'event': [1210], 'remains': [1211, 1852], 'established.Heart': [1214], 'FailureOSA': [1215], 'reported': [1219, 1516], 'CHF,': [1223, 1343], 'up': [1227], '11%.2': [1229], 'Soft': [1230], 'tissue': [1231], 'edema': [1232], '(which': [1233], 'increase': [1235, 1385, 1546, 2630], 'while': [1236], 'supine': [1237], 'sleep)': [1239], 'resistance': [1244], 'inspiratory': [1249], 'force': [1250], 'airway,': [1256], 'thus': [1257], 'increasing': [1258, 1322], 'new-onset': [1262], 'OSA.': [1263], 'Conversely,': [1264], 'data': [1266, 1776], 'CHF.8': [1282], 'could': [1284, 1599], 'predispose': [1285], 'virtue': [1289], 'drive,': [1295], 'function,': [1298, 1350], 'factors': [1311, 1382], 'Moreover,': [1314], 'transmural': [1323], 'pressures': [1324, 1404, 1506], 'wall': [1327], 'stress.': [1328], 'coexistence': [1330], 'create': [1337], 'vicious': [1339], 'cycle': [1340], 'progressing': [1342], 'causing': [1346], 'deterioration': [1347], 'subsequent': [1353], 'exacerbation': [1354], 'OSA.StrokeThe': [1356], 'debatable': [1369], 'what': [1372], 'extent': [1373], 'stroke-induced': [1374], 'abnormalities': [1376], 'association.': [1380], 'stroke': [1389, 1427, 2810], 'include': [1392], 'flow': [1394], 'reduction': [1395, 1721], 'individual': [1397], '(caused': [1400], 'negative': [1402], 'intrathoracic': [1403], 'intracranial': [1407], 'pressure),': [1408], 'atherosclerosis,': [1412], 'standpoint,': [1418], 'observation': [1423], 'survivors': [1428], 'worsened': [1437], 'functional': [1439, 1743], 'outcome.Pulmonary': [1440], 'HypertensionSome': [1441], 'preliminary': [1442, 3651], 'suggested': [1445], 'mild-to-moderate': [1449], 'right': [1455], 'failure)': [1457], 'absence': [1463, 1705], 'lung': [1465], 'In': [1469, 1709, 2341], 'studies,': [1471], 'subjects': [1475, 1906], 'tended': [1476], 'greater': [1480], 'arterial': [1486, 1818, 2464, 3206], 'compared': [1489], 'those': [1491], 'so': [1495], 'contribution': [1498], 'obesity-hypoventilation': [1501], 'syndrome': [1502, 2386, 2390], 'cannot': [1509], 'excluded.Cardiac': [1511], 'ArrhythmiasThe': [1512], 'frequent': [1514], 'arrhythmias': [1515], 'arrest,': [1523], 'sinoatrial': [1524], 'block,': [1525, 1528], 'atrioventricular': [1527], 'asystole.': [1536], 'bradyarrhythmias': [1541, 1598], 'usually': [1543], 'reflex': [1545], 'vagal': [1548], 'tone': [1549, 2255], 'triggered': [1550], 'combination': [1553], 'hypoxemia': [1557, 2396, 2626], '(diving': [1558], 'reflex).': [1559], 'before': [1561], 'pacemaker': [1562], 'recommended': [1565], 'bradyarrhythmias,': [1570], 'diagnosis': [1572, 1856], 'first': [1576], 'considered': [1578, 1897, 1932], 'present,': [1581], 'tried.': [1586], 'Because': [1587], 'sometimes': [1590], 'asleep': [1592], 'day,': [1595], 'attributed': [1601], 'apnea.Several': [1604], 'reports': [1605], 'both': [1614], 'supraventricular': [1615], 'tachyarrhythmias,': [1618], 'latter': [1621], 'setting': [1629], 'comorbidities,': [1633], 'failure.TreatmentBehavioral': [1641], 'lifestyle': [1643], 'modifications,': [1644], 'weight': [1647], 'loss,': [1648], 'avoidance': [1649, 1655], 'sedatives': [1651], 'alcohol,': [1653], 'sleeping': [1657], 'back,': [1660], 'will': [1661, 2293, 2311], 'attenuate': [1663], 'severity.The': [1665], 'treatment': [1666, 1714, 1716, 1858, 2188, 2804], 'choice': [1668], 'generally': [1676], 'accepted': [1677], 'moderate': [1681], 'somnolence': [1687], 'CPAP,': [1692], 'less': [1693], 'clear': [1694, 1775], 'treat': [1700, 3940], 'mild': [1701], 'somnolence.': [1708, 1772], 'short-term,': [1711], 'effective': [1712, 1802], 'severity)': [1724], 'reduce': [1726, 1761], '3)9': [1729], 'pressures,': [1732], 'prevent': [1733], 'depression,': [1736], 'class,': [1744], 'arrhythmias10': [1748], 'Treatment': [1753, 2833, 2886, 3872], 'motor': [1765], 'vehicle': [1766], 'accidents,': [1767], 'probably': [1768], 'lessening': [1770], 'no': [1774, 2287], 'showing': [1777], 'long': [1778], 'term': [1779], 'benefit': [1780], 'regard': [1782], 'points': [1786], 'available.': [1792], '3.': [1796], 'Changes': [1797], '(closed': [1803], 'bars)': [1804, 1808], 'subtherapeutic': [1806], '(open': [1807], '(*P<0.05).': [1814], 'MAP': [1815], 'indicates': [1816], 'mean': [1817], '9.Conclusions': [1825], 'RecommendationsThere': [1827], 'strong': [1829], 'particularly': [1840, 1903], 'For': [1844], 'evidence,': [1849], 'suggestive,': [1851], 'circumstantial.Although': [1853], 'comprehensive': [1855], 'determined': [1864], 'overnight': [1866, 1883], 'polysomnography,': [1867], 'witnessed': [1871], 'somnolence,': [1876], 'oximetry': [1884], 'heighten': [1886], 'suspicion': [1890], 'apnea.OSA': [1894], 'obese': [1905], 'expected': [1909], 'decline': [1911], 'ischemia,': [1921], 'stroke.': [1925], 'Both': [1926], 'who': [1936], 'poorly': [1938], 'responsive': [1939], 'conventional': [1941], 'treatment.FootnotesCorrespondence': [1942], 'Somers,': [1945], 'MD,': [1946], 'PhD,': [1947], 'Divisions': [1948], 'Diseases': [1951], 'Hypertension,': [1953], 'Department': [1954], 'Medicine,': [1956, 2401, 2641, 3075, 3177, 3763, 3915], 'Foundation,': [1958], '200': [1959], 'First': [1960], 'St': [1961], 'SW,': [1962], 'MN': [1964], '55902.': [1965], 'E-mail': [1966], '[email': [1967], 'protected]': [1968], 'References': [1969, 2298], '1': [1970, 3444], 'Young': [1971, 2082], 'T,': [1972, 2083, 2178, 2371, 2618, 2758, 2938, 2980, 3681, 3734, 3859], 'Palta': [1973, 2084], 'M,': [1974, 2085, 2131, 2373, 2416, 2559, 2654, 2778, 2790, 2792, 2848, 2899, 2936, 2982, 3511, 3693, 3730, 3772, 4102, 4106], 'Dempsey': [1975], 'J,': [1976, 2445, 2514, 2569, 2616, 2852, 2944, 2978, 3022, 3276, 3391, 3399, 3515, 3774, 3819, 3855, 3973], 'et': [1977, 2001, 2032, 2055, 2086, 2112, 2134, 2156, 2179], 'al.': [1978, 2002, 2033, 2056, 2087, 2113, 2135, 2157, 2180], 'occurrence': [1980], 'among': [1984], 'adults.': [1986], 'N': [1987, 2098, 2456], 'Engl': [1988, 2099], 'J': [1989, 2100, 2121, 2164, 2574, 2623, 2794, 2987, 3122, 3193, 3401, 3404, 3438, 3476, 3861, 3902, 4052], 'Med.': [1990, 2101, 2168], '1993;': [1991], '328:': [1992], '1230–1235.CrossrefMedlineGoogle': [1993], 'Scholar2': [1994], 'Javaheri': [1995, 2203], 'S,': [1996, 2155, 2367, 2410, 2443, 2714, 2752, 2756, 2770, 3113, 3148, 3152, 3361, 3365, 3561, 3636, 3683, 3689, 3697], 'Parker': [1997], 'TJ,': [1998], 'Liming': [1999], 'JD,': [2000], '81': [2006], 'ambulatory': [2007], 'male': [2008], 'stable': [2011], 'failure:': [2013], 'types': [2014], 'prevalences,': [2017], 'consequences,': [2018], 'presentations.': [2020], 'Circulation.': [2021, 2044, 2075, 2145, 2198, 2222], '1998;': [2022], '97:': [2023], '2154–2159.CrossrefMedlineGoogle': [2024], 'Scholar3': [2025], 'Lanfranchi': [2026, 2132], 'PA,': [2027], 'Braghiroli': [2028], 'A,': [2029, 2176, 2365, 2414, 2650, 2656, 2754, 3016, 3020, 3632, 3640, 3685, 3857, 3920, 3922, 4015], 'Bosimini': [2030], 'E,': [2031, 2151, 2451], 'Prognostic': [2034], 'value': [2035], 'chronic': [2041, 3451], '1999;': [2045], '99:': [2046], '1435–1440.CrossrefMedlineGoogle': [2047], 'Scholar4': [2048], 'Sin': [2049], 'DD,': [2050], 'Logan': [2051], 'AG,': [2052], 'Fitzgerald': [2053], 'FS,': [2054], 'Effects': [2057, 2205, 3782], 'outcomes': [2065], 'respiration.': [2074], '2000;': [2076, 2102, 2223], '102:': [2077], '61–66.LinkGoogle': [2078], 'Scholar5': [2079], 'Peppard': [2080], 'PE,': [2081], 'Prospective': [2088, 3578], 'study': [2089, 2599, 2819], '342:': [2103], '1378–1384.CrossrefMedlineGoogle': [2104], 'Scholar6': [2105], 'VK,': [2107], 'Dyken': [2108], 'ME,': [2109], 'Clary': [2110], 'MP,': [2111], 'Sympathetic': [2114], 'apnea.': [2120, 2144, 2197], 'Clin': [2122], 'Invest.': [2123], '1995;': [2124], '96:': [2125], '1897–1904.CrossrefMedlineGoogle': [2126], 'Scholar7': [2127], 'Shamsuzzaman': [2128], 'AS,': [2129], 'Winnicki': [2130], 'P,': [2133, 2357, 2412, 2449, 3024, 3847, 3900], '2002;': [2146], '105:': [2147], '2462–2464.LinkGoogle': [2148], 'Scholar8': [2149], 'Shahar': [2150], 'Whitney': [2152], 'CW,': [2153], 'Redline': [2154], 'Sleep-disordered': [2158], 'Am': [2163], 'Respir': [2165], 'Crit': [2166], 'Care': [2167], '2001;': [2169], '163:': [2170], '19–25.CrossrefMedlineGoogle': [2171], 'Scholar9': [2172], 'Becker': [2173], 'HF,': [2174], 'Jerrentrup': [2175], 'Ploch': [2177], 'Effect': [2181, 2799, 3032, 3124, 3159], 'nasal': [2183], '2003;': [2199], '107:': [2200], '68–73.LinkGoogle': [2201], 'Scholar10': [2202], 'S.': [2204], 'irritability': [2216], '101:': [2224], '392–397.CrossrefMedlineGoogle': [2225], 'Scholar': [2226], 'eLetters(0)': [2227], 'eLetters': [2228], 'relate': [2230], 'article': [2233, 2306], 'recently': [2234], 'published': [2235, 2274], 'journal': [2238, 2268], 'forum': [2243], 'providing': [2245], 'unpublished': [2246], 'data.': [2247], 'Comments': [2248, 2258, 2271, 2284, 2318], 'reviewed': [2250], 'appropriate': [2252], 'use': [2253], 'language.': [2257], 'peer-reviewed.': [2261], 'Acceptable': [2262], 'comments': [2263], 'posted': [2265, 2296], 'website': [2269], 'only.': [2270], 'issue': [2277], 'indexed': [2281], 'PubMed.': [2283], 'longer': [2288], 'than': [2289, 2737], '500': [2290], 'words': [2291], 'only': [2294], 'online.': [2297], 'limited': [2300], '10.': [2302], 'Authors': [2303], 'cited': [2307], 'comment': [2310], 'invited': [2313], 'reply,': [2315], 'appropriate.': [2317], 'feedback': [2320], 'AHA/ASA': [2322, 2332], 'Scientific': [2323], 'Statements': [2324], 'Guidelines': [2326], 'directed': [2329], 'Manuscript': [2333], 'Oversight': [2334], 'Committee': [2335], 'via': [2336, 2498], 'Correspondence': [2338], 'page.': [2339], 'Sign': [2340], 'Submit': [2343], 'Response': [2345], 'Article': [2348], 'Previous': [2349], 'Back': [2350], 'top': [2352], 'Next': [2353], 'FiguresReferencesRelatedDetailsCited': [2354], 'By': [2355], 'Tondo': [2356], 'Scioscia': [2358], 'G,': [2359, 2369, 2518, 2764, 2766, 3397, 3638, 3642, 3955], 'Sabato': [2360], 'R,': [2361, 2363, 2716, 2780, 2788, 2901, 3272, 3630, 3813, 3924], 'Leccisotti': [2362], 'Hoxhallari': [2364], 'Sorangelo': [2366], 'Mansueto': [2368], 'Campanino': [2370], 'Carone': [2372], 'Foschino': [2374], 'Barbaro': [2375], 'M': [2376, 2903, 2950, 3479, 3644, 3736], 'Lacedonia': [2378], 'D': [2379, 2571, 2658, 3087, 3779], '(2023)': [2380, 2424, 2457, 2486, 2528], 'Mortality': [2381], '(OSAS)': [2387], 'overlap': [2389], '(OS):': [2391], 'compliance,': [2399], '10.1016/j.sleep.2023.10.011,': [2402], '112,': [2403], '(96-103),': [2404], 'Online': [2405, 2475, 2611, 2645, 2707, 2839, 3011, 3055, 3079, 3104, 3181, 3216, 3301, 3426, 3465, 3506, 3556, 3595, 3625, 3723, 3767, 3895, 3949, 4010, 4047, 4062, 4095], 'publication': [2406, 2476, 2612, 2646, 2708, 2840, 3012, 3056, 3080, 3105, 3182, 3217, 3302, 3427, 3466, 3507, 3557, 3596, 3626, 3724, 3768, 3896, 3950, 4011, 4048, 4063, 4096], 'date:': [2407, 2477, 2613, 2647, 2709, 2841, 3013, 3057, 3081, 3106, 3183, 3218, 3303, 3428, 3467, 3508, 3558, 3597, 3627, 3725, 3769, 3897, 3951, 4012, 4049, 4064, 4097], '1-Dec-2023.': [2408], 'Tubek': [2409], 'Niewinski': [2411], 'Langner-Hetmanczuk': [2413], 'Jura': [2415], 'Kuliczkowski': [2417], 'W,': [2418, 2551, 2722, 3519, 3728, 4100], 'Reczuch': [2419], 'K': [2420, 2482, 3699, 3864], 'Ponikowski': [2422], 'P': [2423, 2726, 3119, 3256, 3331, 3568, 3600, 3647, 3977, 3980], 'P2Y12': [2428], 'adenosine': [2429], 'receptors’': [2430], 'inhibitors': [2431], 'peripheral': [2435, 3205], 'chemoreflexes,': [2436], 'Frontiers': [2437, 2870, 3385], 'Physiology,': [2439, 3387, 3461], '10.3389/fphys.2023.1214893,': [2440], '14': [2441], 'Nielsen': [2442], 'Nyvad': [2444], 'Christensen': [2446], 'K,': [2447, 2928, 3018, 3150, 3431, 3472, 3517], 'Poulsen': [2448], 'Laugesen': [2450], 'Grove': [2452], 'E': [2453, 3926], 'Buus': [2455], 'apnea,': [2460, 2971, 3211, 3293], 'calcification': [2462], 'stiffness': [2465, 3207], 'diabetic': [2469], 'kidney': [2470, 3161], 'Atherosclerosis,': [2472, 3212], '10.1016/j.atherosclerosis.2023.06.076,': [2473], '(117170),': [2474], '1-Jun-2023.': [2478], 'Huang': [2479, 2513, 2711, 2713, 2927], 'Y,': [2480, 2712, 2774, 2784, 2930, 2940, 2942, 3115, 3117], 'Chen': [2481, 2523, 2929, 3192, 3392], 'Zhang': [2484, 2560, 3114, 3394, 3403], 'Z': [2485], 'Domain': [2487], '-': [2488, 2504], 'Aware': [2489], 'Spatial-Temporal': [2490], 'Graph': [2491], 'Convolutional': [2492], 'Network': [2493], 'Apnea': [2496, 2677, 2698, 2885, 3036, 3606, 3786, 3997, 4034, 4085], 'Detection': [2497], 'Multivariant': [2499], 'BCG': [2500], 'Signals': [2501], 'ICC': [2502], '2023': [2503], 'IEEE': [2505, 3669], 'International': [2506, 2740, 3294, 3549, 3618, 3665, 3942], 'Conference': [2507, 3666], 'Communications,': [2509], '10.1109/ICC45041.2023.10278967,': [2510], '978-1-5386-7462-8,': [2511], '(5515-5520)': [2512], 'Lian': [2515], 'N,': [2516, 2786, 2846, 2850, 3634, 3691], 'Lin': [2517, 2526, 2939, 2949, 3185, 3735, 3808, 4105], 'Xie': [2519], 'H,': [2520, 2561, 2689, 2782, 2844, 2934, 3513, 3687, 3732, 3959, 3961, 4104], 'Wang': [2521, 2717, 2937, 2952, 3396, 3510], 'B,': [2522, 2718, 3433, 3966, 4071], 'G': [2524, 3776, 3929], 'Q': [2527], 'Expression': [2529], 'alteration': [2530], 'serum': [2532], 'exosomal': [2533], 'circular': [2534], 'RNAs': [2535], 'myocardial': [2543, 3487], 'infarction,': [2544], 'BMC': [2545], 'Medical': [2546], 'Genomics,': [2547], '10.1186/s12920-023-01464-4,': [2548], '16:1': [2549], 'Pan': [2550, 3727, 4099], 'Xia': [2552], 'L,': [2553, 2555, 2557, 2772, 3109], 'Liu': [2554, 3818], 'Gu': [2556], 'Xiang': [2558], 'Wei': [2562], 'X,': [2563, 2567, 3111, 3393, 3807, 3815], 'Yang': [2564], 'Z,': [2565, 3817], 'Zhou': [2566, 3520], 'Li': [2568, 3108, 3116, 3814, 3820], 'Zeng': [2570], 'Jiang': [2573, 3390], '(2022)': [2575, 2624, 2662, 2695, 2730], 'Increased': [2576, 4029], 'diastolic': [2577], 'time': [2582], 'poor': [2586], 'life': [2592], 'quality': [2593], 'primary': [2595], 'snoring:': [2596], 'cohort': [2598], 'combined': [2600], 'external': [2602], 'validation,': [2603], 'Biological': [2606], 'Rhythms,': [2607], '10.1007/s41105-022-00402-8,': [2608], '20:4,': [2609], '(561-568),': [2610], '1-Oct-2022.': [2614], 'Huhtakangas': [2615, 2622, 2977, 2986], 'Saaresranta': [2617, 2979], 'Vähänikkilä': [2619], 'H': [2620, 2953, 4019], 'mortality,': [2631], 'recurrent': [2634], 'events': [2636], '10.1016/j.sleep.2022.05.014,': [2642], '97,': [2643], '(1-9),': [2644], '1-Sep-2022.': [2648], 'Najafi': [2649], 'Mohammadi': [2651], 'I,': [2652, 3060, 3695, 4067], 'Sadeghi': [2653], 'Brühl': [2655], 'Sadeghi-Bahmani': [2657], 'Brand': [2660], 'S': [2661, 2876, 3026, 3029, 3157, 3309], 'Evaluation': [2663, 3908], 'Plasma/Serum': [2665], 'Adiponectin': [2666], '(an': [2667], 'Anti-Inflammatory': [2668], 'Factor)': [2669], 'Levels': [2670], 'Adult': [2672, 3262], 'Syndrome:': [2678, 2911], 'A': [2679, 3084, 3154, 3306, 3616, 3905], 'Systematic': [2680], 'Review': [2681], 'Meta-Analysis,': [2683], 'Life,': [2684], '10.3390/life12050738,': [2685], '12:5,': [2686], '(738)': [2687], 'Ainge‐Allen': [2688], 'Yee': [2690], 'B': [2691, 3065], 'Grunstein': [2693], 'R': [2694, 2879, 2984, 3221, 3334, 4022], 'Clinical': [2699], 'Obesity': [2700], 'Adults': [2702], 'Children,': [2704], '10.1002/9781119695257.ch15,': [2705], '(192-210),': [2706], '11-Mar-2022.': [2710], 'Chung': [2715, 2719], 'C,': [2720, 2724, 2768, 2932, 2946, 2948, 3186, 3188, 3395, 3809, 3849], 'Chien': [2721], 'Sun': [2723, 3738, 4110], 'Yu': [2725], 'Lu': [2728, 3518], 'C': [2729, 2797, 3739, 4073, 4111], 'Obese': [2731], 'Experience': [2733], 'More': [2734], 'Severe': [2735], 'Non-Obese': [2738], 'Patients,': [2739], 'Journal': [2741, 3002, 3049, 3295, 3455, 3500, 3550, 3586, 3619, 3943, 4003], 'Environmental': [2743], 'Research': [2744], 'Public': [2746], 'Health,': [2747], '10.3390/ijerph19031289,': [2748], '19:3,': [2749], '(1289)': [2750], 'Duss': [2751], 'Brill': [2753], 'Baillieul': [2755], 'Horvath': [2757], 'Zubler': [2759], 'F,': [2760, 2776, 3274, 3470, 3851], 'Flügel': [2761], 'D,': [2762, 3363, 3474, 3811, 3853, 3969, 4017], 'Kägi': [2763], 'Benz': [2765], 'Bernasconi': [2767], 'Ott': [2769], 'Korostovtseva': [2771], 'Sviryaev': [2773], 'Salih': [2775], 'Endres': [2777], 'Tamisier': [2779], 'Gouveris': [2781], 'Winter': [2783], 'Denier': [2785], 'Wiest': [2787], 'Arnold': [2789], 'Schmidt': [2791], 'Pépin': [2793], 'Bassetti': [2796], '(2021)': [2798, 2858, 2880], 'early': [2801, 2830], 'apnoea': [2803], 'adaptive': [2806], 'servo-ventilation': [2807], 'cerebral': [2813], 'lesion': [2814], 'evolution': [2815], 'neurological': [2817], 'outcomes:': [2818], 'protocol': [2820], 'multicentre,': [2823], 'randomized': [2824], 'controlled,': [2825], 'rater-blinded,': [2826], 'trial': [2828], '(eSATIS:': [2829], 'Apnoea': [2832, 2910, 3708, 3876], 'Stroke),': [2835], 'Trials,': [2836], '10.1186/s13063-020-04977-w,': [2837], '22:1,': [2838], '1-Dec-2021.': [2842], 'Qin': [2843], 'Steenbergen': [2845], 'Glos': [2847], 'Wessel': [2849], 'Kraemer': [2851], 'Vaquerizo-Villar': [2853], 'F': [2854], 'Penzel': [2856], 'T': [2857, 3281, 3435, 3702], 'Different': [2860, 3195], 'Facets': [2861], 'Rate': [2864, 4118], 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'receptors': [2961], '2': [2962, 4081], '6': [2964, 3793], 'genes': [2965], 'PLOS': [2972, 3142, 3801], 'ONE,': [2973, 3143, 3802], '10.1371/journal.pone.0228958,': [2974], '15:2,': [2975], '(e0228958)': [2976], 'Bode': [2981], 'Bloigu': [2983], '(2019)': [2988, 3030, 3066], 'Stroke': [2989, 2998, 3004], 'Volume': [2990, 4032], 'Predicts': [2991, 4082], 'Hypoxemia': [2993], 'Acute': [2996], 'Ischemic': [2997], 'Intravenous': [3000], 'Thrombolysis,': [3001], 'Cerebrovascular': [3006], 'Diseases,': [3007], '10.1016/j.jstrokecerebrovasdis.2019.06.017,': [3008], '28:9,': [3009], '(2481-2487),': [3010], '1-Sep-2019.': [3014], 'Afzal': [3015], 'Tecson': [3017], 'Jamil': [3019], 'Felius': [3021], 'Garcha': [3023], 'Hall': [3025], 'Carey': [3028], '3-Year': [3038], 'Outcomes': [3039], 'Who': [3042], 'Underwent': [3043], 'Orthotopic': [3044], 'Transplantation,': [3046], 'American': [3048, 3454, 3589], 'Cardiology,': [3051, 3297, 3502, 3552, 3945], '10.1016/j.amjcard.2019.04.005,': [3052], 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