Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2165915920', 'doi': 'https://doi.org/10.1091/mbc.11.9.3247', 'title': 'Paxillin Binding Is Not the Sole Determinant of Focal Adhesion Localization or Dominant-Negative Activity of Focal Adhesion Kinase/Focal Adhesion Kinase-related Nonkinase', 'display_name': 'Paxillin Binding Is Not the Sole Determinant of Focal Adhesion Localization or Dominant-Negative Activity of Focal Adhesion Kinase/Focal Adhesion Kinase-related Nonkinase', 'publication_year': 2000, 'publication_date': '2000-09-01', 'ids': {'openalex': 'https://openalex.org/W2165915920', 'doi': 'https://doi.org/10.1091/mbc.11.9.3247', 'mag': '2165915920', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10982414', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/14989'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1091/mbc.11.9.3247', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc14989?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019416757', 'display_name': 'Marion A. Cooley', 'orcid': 'https://orcid.org/0000-0002-4286-745X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Marion A. Cooley', 'raw_affiliation_strings': ['Departments of Cell Biology & Anatomy,'], 'affiliations': [{'raw_affiliation_string': 'Departments of Cell Biology & Anatomy,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037612687', 'display_name': 'Jill M. Broome', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jill M. Broome', 'raw_affiliation_strings': ['Departments of Cell Biology & Anatomy,'], 'affiliations': [{'raw_affiliation_string': 'Departments of Cell Biology & Anatomy,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025725528', 'display_name': 'Christoph Ohngemach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210147155', 'display_name': 'Pediatrics and Genetics', 'ror': 'https://ror.org/03t432d20', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210147155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christoph Ohngemach', 'raw_affiliation_strings': ['Pediatrics, and'], 'affiliations': [{'raw_affiliation_string': 'Pediatrics, and', 'institution_ids': ['https://openalex.org/I4210147155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077991281', 'display_name': 'Lewis H. Romer', 'orcid': 'https://orcid.org/0000-0002-3780-8500'}, 'institutions': [{'id': 'https://openalex.org/I4210147155', 'display_name': 'Pediatrics and Genetics', 'ror': 'https://ror.org/03t432d20', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210147155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lewis H. Romer', 'raw_affiliation_strings': ['Anesthesiology, and', 'Departments of Cell Biology & Anatomy, Pediatrics, and Anesthesiology, and', 'Pediatrics, and'], 'affiliations': [{'raw_affiliation_string': 'Anesthesiology, and', 'institution_ids': []}, {'raw_affiliation_string': 'Pediatrics, and', 'institution_ids': ['https://openalex.org/I4210147155']}, {'raw_affiliation_string': 'Departments of Cell Biology & Anatomy, Pediatrics, and Anesthesiology, and', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051634622', 'display_name': 'Michael D. Schaller', 'orcid': 'https://orcid.org/0000-0003-3945-5208'}, 'institutions': [{'id': 'https://openalex.org/I4390039329', 'display_name': 'UNC Lineberger Comprehensive Cancer Center', 'ror': 'https://ror.org/043ehm030', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I114027177', 'https://openalex.org/I4390039329']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael D. Schaller', 'raw_affiliation_strings': ['Departments of Cell Biology & Anatomy, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599', 'Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599'], 'affiliations': [{'raw_affiliation_string': 'Departments of Cell Biology & Anatomy, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599', 'institution_ids': ['https://openalex.org/I4390039329', 'https://openalex.org/I114027177']}, {'raw_affiliation_string': 'Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599', 'institution_ids': ['https://openalex.org/I114027177', 'https://openalex.org/I4390039329']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.747, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.786697, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '11', 'issue': '9', 'first_page': '3247', 'last_page': '3263'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10169', 'display_name': 'Protein Kinase Regulation and GTPase Signaling', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/paxillin', 'display_name': 'Paxillin', 'score': 0.9917921}, {'id': 'https://openalex.org/keywords/ptk2', 'display_name': 'PTK2', 'score': 0.9781544}], 'concepts': [{'id': 'https://openalex.org/C116581196', 'wikidata': 'https://www.wikidata.org/wiki/Q14906591', 'display_name': 'Paxillin', 'level': 4, 'score': 0.9917921}, {'id': 'https://openalex.org/C151166631', 'wikidata': 'https://www.wikidata.org/wiki/Q904514', 'display_name': 'Focal adhesion', 'level': 3, 'score': 0.9802323}, {'id': 'https://openalex.org/C108391706', 'wikidata': 'https://www.wikidata.org/wiki/Q15333532', 'display_name': 'PTK2', 'level': 5, 'score': 0.9781544}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.66666126}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6622523}, {'id': 'https://openalex.org/C2777553839', 'wikidata': 'https://www.wikidata.org/wiki/Q14330986', 'display_name': 'Tyrosine phosphorylation', 'level': 3, 'score': 0.64093024}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.58131146}, {'id': 'https://openalex.org/C2776165026', 'wikidata': 'https://www.wikidata.org/wiki/Q188017', 'display_name': 'Tyrosine', 'level': 2, 'score': 0.49468538}, {'id': 'https://openalex.org/C84416704', 'wikidata': 'https://www.wikidata.org/wiki/Q188666', 'display_name': 'Adhesion', 'level': 2, 'score': 0.468433}, {'id': 'https://openalex.org/C85789140', 'wikidata': 'https://www.wikidata.org/wiki/Q187640', 'display_name': 'Cell adhesion', 'level': 3, 'score': 0.45521352}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.4348883}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.24426547}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.1520279}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.091774315}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.084468395}, {'id': 'https://openalex.org/C90934575', 'wikidata': 'https://www.wikidata.org/wiki/Q6593810', 'display_name': 'Mitogen-activated protein kinase kinase', 'level': 4, 'score': 0.03739068}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016475', 'descriptor_name': '3T3 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002642', 'descriptor_name': 'Chick Embryo', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D051417', 'descriptor_name': 'Focal Adhesion Kinase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051416', 'descriptor_name': 'Focal Adhesion Protein-Tyrosine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014644', 'descriptor_name': 'Genetic Variation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016297', 'descriptor_name': 'Mutagenesis, Site-Directed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051419', 'descriptor_name': 'Paxillin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016415', 'descriptor_name': 'Sequence Alignment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017386', 'descriptor_name': 'Sequence Homology, Amino Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1091/mbc.11.9.3247', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc14989', 'pdf_url': 'https://europepmc.org/articles/pmc14989?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://cdr.lib.unc.edu/downloads/p26772311', 'pdf_url': 'https://cdr.lib.unc.edu/downloads/p26772311', 'source': {'id': 'https://openalex.org/S4306401075', 'display_name': 'Carolina Digital Repository (University of North Carolina at Chapel Hill)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I114027177', 'host_organization_name': 'University of North Carolina at Chapel Hill', 'host_organization_lineage': ['https://openalex.org/I114027177'], 'host_organization_lineage_names': ['University of North Carolina at Chapel Hill'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC14989', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10982414', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc14989', 'pdf_url': 'https://europepmc.org/articles/pmc14989?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 65, 'referenced_works': ['https://openalex.org/W1549544590', 'https://openalex.org/W1785533687', 'https://openalex.org/W1912221395', 'https://openalex.org/W1926397135', 'https://openalex.org/W1927489048', 'https://openalex.org/W1929023701', 'https://openalex.org/W1930335657', 'https://openalex.org/W1968947906', 'https://openalex.org/W1977426071', 'https://openalex.org/W1977585994', 'https://openalex.org/W1989776883', 'https://openalex.org/W1994651714', 'https://openalex.org/W1997121235', 'https://openalex.org/W1999788892', 'https://openalex.org/W2000983089', 'https://openalex.org/W2006892275', 'https://openalex.org/W2018289835', 'https://openalex.org/W2025018535', 'https://openalex.org/W2028691987', 'https://openalex.org/W2034569034', 'https://openalex.org/W2034710767', 'https://openalex.org/W2043117244', 'https://openalex.org/W2043151616', 'https://openalex.org/W2043503095', 'https://openalex.org/W2043761739', 'https://openalex.org/W2053582875', 'https://openalex.org/W2054779757', 'https://openalex.org/W2058649760', 'https://openalex.org/W2059035317', 'https://openalex.org/W2059188737', 'https://openalex.org/W2063259786', 'https://openalex.org/W2068540074', 'https://openalex.org/W2071516872', 'https://openalex.org/W2071852938', 'https://openalex.org/W2076544187', 'https://openalex.org/W2078766771', 'https://openalex.org/W2079051863', 'https://openalex.org/W2081135891', 'https://openalex.org/W2082218239', 'https://openalex.org/W2085294978', 'https://openalex.org/W2085846371', 'https://openalex.org/W2086992732', 'https://openalex.org/W2100837269', 'https://openalex.org/W2103363752', 'https://openalex.org/W2104539756', 'https://openalex.org/W2104679668', 'https://openalex.org/W2105356859', 'https://openalex.org/W2105512558', 'https://openalex.org/W2107164894', 'https://openalex.org/W2116312858', 'https://openalex.org/W2119222825', 'https://openalex.org/W2120346794', 'https://openalex.org/W2122875377', 'https://openalex.org/W2127286098', 'https://openalex.org/W2137022580', 'https://openalex.org/W2139471842', 'https://openalex.org/W2140506935', 'https://openalex.org/W2144020592', 'https://openalex.org/W2156451315', 'https://openalex.org/W2162784878', 'https://openalex.org/W2167836317', 'https://openalex.org/W2413551838', 'https://openalex.org/W4234113840', 'https://openalex.org/W4236302049', 'https://openalex.org/W4249092084'], 'related_works': ['https://openalex.org/W4299484413', 'https://openalex.org/W4256550678', 'https://openalex.org/W4220838032', 'https://openalex.org/W2165915920', 'https://openalex.org/W2157627838', 'https://openalex.org/W2144020592', 'https://openalex.org/W2126892899', 'https://openalex.org/W2083971379', 'https://openalex.org/W2072583244', 'https://openalex.org/W2027197074'], 'abstract_inverted_index': {'The': [0, 22, 64], 'carboxy-terminal': [1], '150': [2], 'residues': [3], 'of': [4, 24, 38, 43, 50, 62, 76, 87, 106, 113, 141, 148, 154], 'the': [5, 11, 39, 48, 60, 85, 139, 145, 151], 'focal': [6, 12, 25, 40, 51, 73, 92, 133], 'adhesion': [7, 26, 52, 74, 95], 'kinase': [8], '(FAK)': [9], 'comprise': [10], 'adhesion-targeting': [13, 41], 'sequence,': [14], 'which': [15], 'is': [16, 70], 'responsible': [17], 'for': [18, 72, 101, 122, 138], 'its': [19], 'subcellular': [20], 'localization.': [21], 'mechanism': [23, 49], 'targeting': [27, 53, 75, 96], 'has': [28, 169], 'not': [29, 158], 'been': [30], 'fully': [31], 'elucidated.': [32], 'We': [33], 'describe': [34], 'a': [35, 99], 'mutational': [36], 'analysis': [37], 'sequence': [42], 'FAK': [44, 115], 'to': [45, 89, 91, 132, 163, 174], 'further': [46], 'examine': [47], 'and': [54, 108], 'explore': [55], 'additional': [56, 120], 'functions': [57, 125], 'encoded': [58], 'by': [59], 'carboxy-terminus': [61], 'FAK.': [63, 77], 'results': [65], 'demonstrate': [66], 'that': [67, 130, 167], 'paxillin': [68, 107, 142], 'binding': [69], 'dispensable': [71], 'Cell': [78], 'adhesion-dependent': [79], 'tyrosine': [80, 104], 'phosphorylation': [81, 105, 143], 'strictly': [82], 'correlated': [83], 'with': [84, 160], 'ability': [86, 162], 'mutants': [88, 129, 156], 'target': [90, 131], 'adhesions.': [93], 'Focal': [94], 'was': [97], 'also': [98], 'requirement': [100], 'maximal': [102], 'FAK-dependent': [103], 'FAK-related': [109], 'nonkinase': [110], '(FRNK)–dependent': [111], 'inhibition': [112], 'endogenous': [114], 'function.': [116], 'However,': [117], 'there': [118], 'were': [119], 'requirements': [121], 'these': [123], 'latter': [124], 'because': [126], 'we': [127], 'identified': [128], 'adhesions,': [134], 'yet': [135], 'are': [136], 'defective': [137], 'induction': [140], 'or': [144], 'dominant-negative': [146], 'function': [147], 'FRNK.': [149], 'Furthermore,': [150], 'paxillin-binding': [152], 'activity': [153], 'FRNK': [155, 168], 'did': [157], 'correlate': [159], 'their': [161], 'inhibit': [164], 'FAK,': [165], 'suggesting': [166], 'other': [170], 'targets': [171], 'in': [172], 'addition': [173], 'paxillin.': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2165915920', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T03:05:52.646799', 'created_date': '2016-06-24'}