Publication Information

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'share': [357, 380], 'version': [359, 383, 1178, 4002], 'article.I': [361], 'have': [362, 464, 2097, 2260, 2354, 2368, 2384, 3543, 3562, 3566, 4102], 'read': [363], 'accept': [365], 'the': [366, 376, 410, 413, 418, 439, 480, 507, 513, 520, 586, 614, 622, 735, 792, 822, 851, 919, 965, 968, 1061, 1074, 1095, 1104, 1107, 1119, 1122, 1125, 1129, 1140, 1158, 1165, 1180, 1273, 1536, 1544, 1551, 1577, 1602, 1727, 1734, 1765, 1771, 1793, 1816, 1819, 1829, 1840, 1865, 1872, 1937, 1943, 1955, 1992, 2011, 2047, 2127, 2131, 2179, 2186, 2301, 2309, 2315, 2350, 2392, 2511, 2530, 2578, 2581, 2696, 2712, 2760, 2846, 2890, 2932, 2956, 2971, 2997, 3025, 3057, 3064, 3068, 3216, 3259, 3274, 3311, 3509, 3516, 3538, 3550, 3585, 3591, 3601, 3619, 3643, 3734, 3741, 3788, 3793, 3799, 3821, 4000, 4004, 4020, 4026], 'Wiley': [367], 'Online': [368], 'Library': [369], 'UseShareable': [374], 'LinkUse': [375], 'link': [377], 'a': [381, 399, 465, 471, 617, 706, 742, 784, 818, 854, 1049, 1143, 1527, 1662, 1670, 1742, 1748, 1752, 1844, 1848, 1887, 1912, 1918, 1925, 1929, 1985, 2074, 2123, 2143, 2147, 2319, 2340, 2386, 2396, 2400, 2543, 2553, 2628, 2668, 2737, 2806, 2869, 2985, 3544, 3564, 3571, 4034], 'article': [386], 'with': [387, 483, 527, 546, 554, 691, 709, 875, 1110, 1391, 1410, 1423, 1436, 1452, 1483, 1512, 1535, 1557, 1568, 1589, 1617, 1648, 1751, 1805, 1892, 2017, 2025, 2073, 2084, 2101, 2183, 2198, 2207, 2242, 2265, 2347, 2378, 2421, 2536, 2552, 2556, 2610, 2617, 2667, 2683, 2715, 2726, 2736, 2766, 2805, 2864, 2905, 2966, 2984, 2992, 3009, 3203, 3820], 'your': [388], 'friends': [389], 'colleagues.': [391], 'Learn': [392], 'more.Copy': [393], 'URL': [394], 'Definition': [395], 'is': [398, 490, 509, 569, 591, 727, 741, 772, 799, 812, 921, 1022, 1171, 1183, 1532, 1546, 1669, 1741, 1823, 1846, 1853, 1857, 1884, 1890, 1924, 1939, 1948, 1991, 2193, 2212, 2225, 2507, 2522, 2532, 2546, 2570, 2590, 2623, 2689, 2692, 2732, 2783, 2875, 2893, 2903, 2934, 3075, 3736, 3740, 3981], 'malignant': [400, 420, 732], 'tumor': [401, 887, 920, 981, 1038, 1109, 1127, 1193, 1210, 1365, 1378, 1442, 1450, 1457, 1467, 1481, 1491, 2085, 2205, 2240, 2246, 2531, 2545, 2568, 2582, 2901, 3026, 3511, 3592, 3653, 3723], 'which': [402, 677, 752, 2000, 2520, 2594], 'arises': [403, 778], 'from': [404, 783, 1094, 2881], 'melanocytic': [405, 550], 'cells': [406], 'primarily': [408, 743, 2935], 'involves': [409], 'skin.': [411], 'For': [412, 1786, 1907, 2764], 'balance': [414], 'these': [416, 581, 1597, 3997], 'guidelines,': [417], 'terms': [419], 'will': [424, 4006], 'be': [425, 649, 905, 934, 1215, 1612, 1684, 1710, 1720, 1777, 1803, 1905, 1933, 1967, 1978, 2020, 2158, 2550, 2608, 2635, 2643, 2680, 2756, 2857, 2868, 2940, 3267, 3298, 3303, 3728, 4007], 'used': [426, 1778, 2106, 2666, 2757], 'interchangeably,': [427], 'because': [428, 2307], 'there': [429, 456, 811, 1822, 2034, 2121, 2141, 2173], 'are': [430, 452, 457, 533, 561, 608, 661, 668, 1005, 1070, 1562, 1585, 1696, 1837, 1957, 1974, 2035, 2056, 2068, 2174, 2272, 2327, 2574, 2595, 2647, 2665, 2701, 2778, 2824, 2833, 2920, 3012, 3043, 3222, 3252, 3294, 3524, 3634, 3998], 'no': [431, 1209, 1384, 1403, 1416, 1429, 1444, 1459, 1824, 1833, 2036, 2175, 2213, 2742], 'benign': [432], 'melanomas.': [433, 685], 'Melanomas': [434, 475, 1056], 'can': [435, 648, 1057, 1084, 1611, 1801, 1904, 2606, 2641, 2679, 2755, 3055], 'also': [436, 458, 721, 1154, 1802, 2353, 2607, 2642, 2825], 'arise': [437], 'in': [438, 493, 512, 518, 575, 620, 636, 739, 768, 912, 959, 973, 1173, 1207, 1566, 1606, 1634, 1722, 1725, 1770, 1792, 1877, 1896, 1971, 2004, 2046, 2058, 2070, 2118, 2153, 2218, 2235, 2263, 2288, 2300, 2305, 2343, 2372, 2376, 2391, 2403, 2516, 2519, 2809, 2822, 2835, 2851, 2970, 2996, 3031, 3045, 3232, 3254, 3337, 3636, 3649, 3784, 3990], 'eye': [440], '(conjunctiva': [441], 'uvea),': [443], 'meninges': [444], 'on': [446, 539, 791, 923, 1043, 1260, 1550, 1756, 1782, 1815, 1839, 1980, 2178, 2945, 3112, 3135, 3508, 3798], 'various': [447], 'mucosal': [448, 543, 671], 'surfaces.': [449], 'While': [450], 'melanomas': [451, 532, 573, 647, 913, 1004, 1169, 1559, 1787, 3612], 'usually': [453, 800], 'heavily': [454], 'pigmented,': [455], 'amelanotic': [459, 669], 'tumors.': [460, 485, 840, 1714], 'Even': [461], 'small': [462], 'tumors': [463, 655, 951, 1009, 1021, 1688, 2804], 'tendency': [466, 3545], 'towards': [467, 2146, 3546], 'metastasis': [468, 1083, 1335, 1356], 'thus': [470, 3028], 'relatively': [472], 'unfavorable': [473, 1694], 'prognosis.': [474], 'account': [476, 679], '90%': [478, 1002, 3528], 'deaths': [481], 'associated': [482, 1588], 'cutaneous': [484, 3089, 3324], 'The': [486, 565, 596, 610, 1015, 1025, 1523, 1540, 1736, 1759, 2038, 2269, 2686, 2698, 2780, 2786, 2859, 2879, 2912, 3036, 3048, 3219, 3246, 3500, 3518, 3716, 3978], 'incidence': [487, 508], 'increasing': [491], 'worldwide': [492], 'white': [494], 'populations,': [495], 'especially': [496], 'where': [497, 2134, 2598, 3628], 'fair-skinned': [498], 'peoples': [499], 'receive': [500, 3763], 'excessive': [501], 'sun': [502], 'exposure.': [503], 'In': [504, 525, 578, 806, 1138, 1376, 1555, 1950, 2081, 2130, 2734, 2949, 3995, 4025], 'central': [505], 'Europe': [506, 2306], '10–12/100,000': [510], 'yearly;': [511, 516], 'USA,': [514], '10-25/100,000': [515], 'Australia': [519], 'highest': [521], 'incidence,': [522], '50-60/100,000': [523], 'yearly.': [524], 'individuals': [526, 638], 'pigmentation': [529], '(Asians,': [530], 'Africans)': [531], 'uncommon': [534], 'almost': [536, 773, 789], 'always': [537], 'found': [538], 'either': [540, 656, 1059, 2770], 'acral': [541, 1653], 'or': [542, 632, 660, 695, 749, 802, 804, 857, 895, 929, 987, 992, 1063, 1229, 1258, 1264, 1308, 1315, 1341, 1393, 1399, 1475, 1496, 1499, 1507, 1810, 1920, 1935, 2208, 2524, 2649, 2716, 2772, 2792, 2918, 3001, 3082, 3106, 3199, 3229, 3238, 3596, 3753, 3756, 4037], 'surface.': [544], 'Individuals': [545], 'large': [547, 2331], 'numbers': [548], 'nevi': [551], 'those': [553, 1567, 2517, 2991], 'precursors': [556, 3609], '(dysplastic': [557], 'nevi,': [558], 'congenital': [559], 'nevi)': [560], 'at': [562, 2050, 3600, 4009], 'greater': [563], 'risk.': [564], 'inheritance': [566], 'polygenic;': [570], '5-10%': [571], 'appear': [574, 1085, 2843], 'melanoma-prone': [576], 'families.': [577], 'addition': [579], 'genetic': [582], 'constitutional': [584], 'factors,': [585], 'most': [587, 1026, 1586, 3525], 'important': [588, 1027], 'exogenous': [589], 'factor': [590], 'exposure': [592], 'UV': [594], 'irradiation.': [595], 'relative': [597], 'roles': [598], 'toxic': [600, 3224], 'substances,': [601], 'medications': [602, 3037], 'hormones': [604], '(pregnancy,': [605], 'oral': [606, 3306], 'contraceptives)': [607], 'controversial.': [609], 'immune': [611], 'status': [612, 1769, 1931], 'patient': [615, 1873], 'plays': [616], 'major': [618, 2699], 'role': [619], 'determining': [621], 'course': [623, 3621], 'melanoma,': [625, 886, 1654, 3573], 'as': [626, 700, 907, 990, 1007, 1098, 1100, 2031, 2033, 2170, 2172, 2298, 2560, 3174, 3514, 3527, 3730, 3803, 4033], 'numerous': [627], 'examples': [628], 'spontaneous': [630], 'regression': [631, 3023], 'rapid': [634, 2453], 'progression': [635, 3599], 'immunosuppressed': [637], 'bear': [639], 'testimony.': [640], 'A': [641, 723, 1081, 1176, 2250, 2330, 2720, 3005], 'number': [642, 3006], 'different': [644], 'types': [645], 'identified': [650], 'clinically': [651], 'histologically.': [653], 'Some': [654], 'represent': [657], 'mixed': [658], 'forms': [659, 667, 1164, 2072, 3710], 'not': [662, 1262, 1563, 1747, 1858, 1940, 2525, 2602, 3594, 4103], 'classifiable.': [663], 'Examples': [664], 'special': [666, 3233], 'melanomas,': [670, 672, 676], 'other': [674, 858, 1350, 1693, 2324, 2803, 3339, 3539], 'extracutaneous': [675], 'together': [678], 'about': [681, 3992], '5%': [682], 'all': [684, 1019, 1687, 2023, 2119, 2196, 2887, 3530, 3709], 'Superficial': [686], 'spreading': [687], '(SSM)': [689], 'starts': [690], 'an': [692, 761, 769, 876, 1111, 1590, 1806, 1981, 2026, 2284, 2355, 2826, 3029, 3567], 'intraepidermal': [693, 770, 809], 'horizontal': [694, 756], 'radial': [696], 'growth': [697, 757, 824], 'phase,': [698, 810], 'starting': [699], 'macule': [701], 'slowly': [703], 'evolving': [704], 'into': [705, 2604], 'plaque,': [707], 'often': [708, 747, 779, 2693], 'multiple': [710, 1893], 'colors': [711], 'pale': [713], 'areas': [714, 719], 'regression.': [716], 'Secondary': [717], 'nodular': [718, 819], 'may': [720, 1660, 1776, 2867, 3021, 3231], 'develop.': [722], 'characteristic': [724], 'histologic': [725, 1743], 'feature': [726], 'pagetoid': [728], 'spread': [729], 'clear': [731, 2144], 'melanocytes': [733], 'throughout': [734], 'epidermis.': [736], 'Nodular': [737], 'contrast': [740, 2289], 'nodular,': [744], 'exophytic': [745], 'brown-black,': [746], 'eroded': [748], 'bleeding': [750], 'tumor,': [751], 'has': [753, 1152, 1874, 2001, 2295, 2652, 2799, 3584, 3593, 4031], 'only': [754, 2051, 2318, 2508, 3742], 'short': [755, 3775], 'phase': [758], 'then': [760, 1945, 3141, 3145], 'aggressive': [762], 'vertical': [763], 'phase.': [764], 'Thus': [765, 2014, 2151], 'early': [766, 808, 3602], 'identification': [767], 'stage': [771, 2200, 3604], 'impossible.': [774], 'Lentigo': [775], 'maligna': [776, 786, 1650], 'after': [780, 3448, 3466], 'many': [781], 'years': [782, 2500, 3521, 4029], 'lentigo': [785, 1649, 1677], '(melanoma': [787], 'in-situ)': [788], 'exclusively': [790], 'face': [793], 'elderly': [795], 'individuals.': [796], 'Acral-lentiginous': [797], 'palmoplantar,': [801], 'sub-': [803], 'periun-gual.': [805], 'its': [807, 2943], 'irregular,': [813], 'poorly': [814], 'circumscribed': [815], 'pigmentation;': [816], 'later': [817], 'region': [820], 'signals': [821], 'invasive': [823], 'pattern.': [825], 'Preoperative': [826], 'Staging': [828, 1000, 1360], 'Evaluation': [829], 'Required': [830], 'Examinations': [831], '•': [832, 841, 861, 871, 879, 899, 936, 956, 962, 976, 984, 1036, 1046, 1053, 1087, 1115, 1133, 4042, 4046, 4050, 4053, 4057, 4060, 4065, 4068, 4071, 4075, 4078, 4082, 4085, 4088, 4092, 4096], 'Dermatoscopy': [833], 'enhance': [835], 'differential': [836], 'diagnosis': [837, 874, 881], 'pigmented': [839], 'Clinical': [842], 'evaluation': [843, 938, 989], 'draining': [845], 'lymphatic': [846, 1062], 'pathways': [847], 'exclude': [850], 'presence': [852, 894], 'second': [855, 3572, 3611], 'precursors.': [860], 'Lymph': [862, 3663], 'node': [863, 902, 927, 1136, 1290, 1319, 1343, 1369, 1501, 1514, 1681, 1707, 1717, 1739, 1762, 1799, 1851, 1910, 1915, 2188, 2267, 2380, 2639, 3664], 'sonography': [864, 978, 3665, 3749], 'lesions': [866], 'thicker': [867, 914, 952, 1689, 1788], 'than': [868, 915, 953, 1789, 2896, 2989, 3210, 3225], '1': [869, 916, 954, 1293, 1640, 1790, 2485, 2496, 3336, 3363, 3368, 3372, 3380, 3403, 3409, 3419, 3428, 3436, 3460, 3479, 3488, 3588, 3680, 3691, 4110], 'mm.': [870, 917, 955, 1691], 'Confirmation': [872], 'excisional': [877], 'biopsy.': [878], 'Histopathologic': [880], 'should': [882, 904, 933, 1683, 1709, 1719, 1966, 1977, 2019, 2157, 2549, 2634, 2856, 2939, 2953, 3297, 3302, 3554, 3727, 3762], 'include': [883], 'type': [884], 'thickness': [888, 1039, 1199, 1257, 1451, 1468, 1482, 1492, 1630, 2086, 2241, 2247, 3654, 3724], '(Breslow': [889, 1040], 'depth),': [890], 'Clark': [891, 1054, 1394], 'level,': [892], 'absence': [896], 'ulceration.': [898], 'Sentinel': [900, 1679, 1715], 'lymph': [901, 926, 1079, 1131, 1135, 1275, 1284, 1289, 1342, 1368, 1500, 1513, 1680, 1706, 1716, 1738, 1761, 1773, 1798, 1831, 1841, 1850, 1909, 1914, 2266, 2379, 2638, 2975], 'biopsy': [903, 1682, 1708, 1740, 1763], 'performed': [906, 1613, 1685, 1721, 2262], 'part': [908], 'routine': [910], 'staging': [911, 996, 1148, 1744, 1800], 'When': [918, 1646, 1871, 1886, 2542, 2565], 'located': [922], 'face,': [924], 'elective': [925, 1807], 'dissection': [928, 1809, 1852, 1916], 'parotid': [930, 1811], 'gland': [931, 1812], 'excision': [932, 1113, 1534, 1545, 1603, 1625, 1881], 'considered.': [935, 1906, 2329, 2858], 'Laboratory': [937], 'includes': [939, 3708], 'sed': [940], 'rate,': [941], 'CBC,': [942], 'LDH,': [943], 'alkaline': [944], 'phosphates': [945], 'serum': [947], 'S100': [948, 3669], 'protein': [949, 3670, 3739], 'Chest': [957], 'X-ray': [958], 'two': [960, 2039, 2052], 'planes.': [961], 'Sonography': [963], 'abdomen': [966], 'including': [967], 'pelvis': [969], 'retroperitoneum.': [971], 'Useful': [972], 'Selected': [974], 'Cases': [975], 'High-resolution': [977], 'measure': [980, 1750], 'depth': [982], 'preoperatively.': [983], 'CT,': [985], 'MRI': [986, 3755], 'PET': [988], 'alternative': [991, 1672], 'supplement': [993], 'above-mentioned': [995], 'examinations.': [997], 'Prognosis': [998], 'About': [1001, 1066], 'diagnosed': [1006], 'primary': [1008, 1031, 1096, 1108, 1126, 1192, 1266, 1524, 1618, 1703, 2512], 'without': [1010, 1033, 2089, 2209, 2248, 2717], 'any': [1011, 4105], 'evidence': [1012, 1860, 2090], 'metastasis.': [1014, 1554, 2964, 3715], 'tumor-specific': [1016], '10-year-survival': [1017], 'such': [1020], 'around': [1023], '75–80%.': [1024], 'prognostic': [1028, 1201], 'factors': [1029, 1598], 'metastases': [1034, 1069, 1089, 1117, 1137, 1291, 1310, 1317, 1327, 1352, 1370, 1373, 1477, 1511, 1518, 1883, 1956, 2593, 2640, 2678, 2821, 2925, 2928, 3293, 3531, 3548], 'are:': [1035], 'Vertical': [1037], 'depth)': [1041], 'measured': [1042], 'histological': [1044], 'specimen': [1045], 'Presence': [1047], 'histologically': [1050], 'recognizable': [1051], 'ulceration': [1052, 1237, 1245, 1253, 1261, 1385, 1392, 1404, 1411, 1417, 1424, 1430, 1437, 1445, 1453, 1460, 1470, 1484, 1494, 1701], 'level': [1055, 1699], 'metastasize': [1058], 'hematogenous': [1064], 'routes.': [1065], 'two-thirds': [1067], 'originally': [1071], 'confined': [1072], 'drainage': [1075], 'area': [1076], 'regional': [1078, 1082, 1274, 1772, 1908, 2924, 3714], 'nodes.': [1080, 1842], 'as:': [1086], 'Satellite': [1088, 1307], '(up': [1090, 2751], '2': [1092, 1644, 2561, 2839, 3192, 3605, 4028], 'cm': [1093, 1637, 1641, 1645], 'tumor),': [1097, 1704], 'well': [1099], 'local': [1101, 1594, 1615, 2789, 2854, 3712], 'recurrence': [1102], 'following': [1103, 3522, 3586, 4021], 'removal': [1105, 2657], 'inadequate': [1112], 'margin': [1114, 1542, 1633, 1664, 2555], 'In-transit': [1116, 2592], '(in': [1118], 'skin': [1120], 'between': [1121, 2955, 3779, 3787], 'site': [1123, 1817], 'first': [1130, 1993, 2229, 3519], 'node)': [1132], 'Regional': [1134, 1367, 2637], '2001,': [1139], 'AJCC': [1141, 3718], 'proposed': [1142], 'new': [1144, 1161, 1177, 3717], 'TNM': [1145], 'classification': [1146, 1182, 1190, 1197, 1271, 1280, 1324, 1331, 2182], 'melanoma;': [1150], 'it': [1151, 2548, 2874], 'now': [1153, 1163], 'been': [1155, 2002, 2098, 2261, 2296, 2800], 'accepted': [1156, 2297, 4038], 'UICC.': [1159], 'This': [1160, 2293, 3773], 'system': [1162], 'cornerstone': [1166], 'classifying': [1168], 'summarized': [1172, 3044], 'Tables': [1174], '1–4.': [1175], 'TMN': [1181], 'currently': [1184], 'being': [1185, 2226, 2328], 'developed.': [1186], 'Table': [1187, 1268, 1321, 1358, 1607, 1622, 2412, 3046, 3084, 3255, 3317, 3637, 3639], '1.': [1188], 'T': [1189, 1196], 'melanoma.': [1195, 1278, 1329, 1362, 1628, 3018, 3090, 3325], 'Tumor': [1198, 1629], 'Additional': [1200], 'parameters': [1202], 'Tis': [1203], 'No': [1204, 1223, 1236, 1244, 1252], 'information': [1205, 1259], 'Melanoma': [1206], 'situ,': [1208], 'invasion': [1211], 'Tx': [1212], 'Stage': [1213, 1363, 1529, 1951, 2236, 2442, 2461, 2476, 2490, 2501, 2950, 3651, 3719, 3731], 'cannot': [1214, 1932], 'determined*': [1216], 'T1': [1217], '<': [1218, 3679], '=': [1219], '1.0': [1220], 'mm': [1221, 1234, 1242, 1250, 1390, 1409, 1422, 1435, 1639, 1643, 1791, 2088, 2204, 2239, 2245, 3681, 3692, 3722], 'a:': [1222, 1235, 1243, 1251, 1295, 1302], 'ulceration,': [1224, 2243], 'Level': [1225, 1230, 1397], 'II–III': [1226], 'b:': [1227, 1238, 1246, 1254, 1297, 1304], 'Ulceration': [1228, 1239, 1247, 1255], 'IV–V': [1231], 'T2': [1232], '1.01–2.0': [1233, 1401, 1408], 'T3': [1240], '2.01–4.0': [1241, 1414, 1421], 'T4': [1248], '>4.0': [1249, 1427, 1434], '*Tumor': [1256], 'available,': [1263], 'unknown': [1265], 'tumor.': [1267, 1820], '2.': [1269], 'N': [1270, 1279], 'nodes': [1276, 1285, 1774], 'Number': [1281], 'involved': [1283, 1891], '(LN)': [1286], 'Extent': [1287], 'N1': [1292], 'LN': [1294, 1301], 'Micrometastases': [1296, 1303, 1446, 1454], 'Macrometastases': [1298, 1305], 'N2': [1299], '2–3': [1300], 'c:': [1306], 'in-transit': [1309, 1316, 1476], 'N3': [1311], '≥4': [1312], 'LN,': [1313], 'satellite': [1314, 1473, 1508, 1875, 1894], 'plus': [1318], 'involvement': [1320, 1503, 1515, 1827], '3.': [1322], 'M': [1323, 1330], 'distant': [1326, 1334, 1351, 1355, 1580, 2360, 2927], 'Type': [1332], 'LDH': [1336], 'M1a': [1337], 'Skin,': [1338], 'subcutaneous': [1339], 'tissue': [1340], 'Normal': [1344, 1347, 1353], 'M1b': [1345], 'Lungs': [1346], 'M1c': [1348], 'All': [1349, 1596, 2104, 4099], 'Any': [1354, 1441, 1449, 1456, 1466, 1480, 1490], 'Elevated': [1357], '4.': [1359], 'Primary': [1364], '(pT)': [1366], '(N)': [1371], 'Distant': [1372, 1517], '(M)': [1374], '0': [1375], 'situ': [1377, 1635], 'None': [1379, 1380, 1386, 1387, 1395, 1396, 1405, 1406, 1412, 1413, 1418, 1419, 1425, 1426, 1431, 1432, 1438, 1439, 1447, 1455, 1465, 1471, 1478, 1489, 1502, 3684, 3685, 3686], 'IA': [1381], '≤1.0': [1382, 1389], 'mm,': [1383, 1402, 1415, 1428], 'IB': [1388], 'IV': [1398, 1516, 1952, 2951, 3704], 'V': [1400], 'IIA': [1407, 2201], 'IIB': [1420, 2237], 'IIC': [1433, 3720], 'IIIA': [1440], 'thickness,': [1443, 1458, 2206], 'IIIB': [1448], 'Up': [1461, 1485], 'three': [1463, 1487, 2093], 'macrometastases': [1464, 1488], '±': [1469, 1493], 'but': [1472, 2539, 2873, 3212], 'and/': [1474], 'IIIC': [1479], 'Four': [1495], 'macrometastases,': [1498], 'extending': [1504], 'beyond': [1505], 'capsule,': [1506], 'and/or': [1509, 1876, 1895], 'intransit': [1510], 'Therapy': [1519, 1522, 1870, 1989, 2504], 'Curative': [1520], 'Surgical': [1521, 1869], 'treatment': [1525, 2513, 2762, 2933], 'biopsy-proven': [1528], 'I': [1530, 3687], 'surgical': [1533, 1835, 1964], 'goal': [1537], 'cure.': [1539], 'safety': [1541], 'variable': [1547], 'based': [1549, 3797], 'risk': [1552, 1578, 1592, 2028, 2155, 2221, 3312, 3569], 'patients': [1556, 2024, 2083, 2135, 2152, 2197, 2234, 2264, 2322, 2377, 2765, 3560, 3583, 3647], 'thin': [1558], 'extensive': [1560, 2960, 2993], 'procedures': [1561, 1610, 1836], 'needed;': [1564], 'conversely': [1565], 'thick': [1569], 'tumors,': [1570], 'radical': [1571, 1849, 1913], 'surgery': [1572, 1656, 1674, 2521, 2651, 2771, 3523], 'does': [1573, 2601, 3515, 3542], 'little': [1574], 'influence': [1576], 'metastases.': [1581, 2268, 2361, 2381], 'Too': [1582], 'narrow': [1583], 'margins': [1584, 1626], 'likely': [1587], 'increased': [1591, 2027, 2356, 3568, 3575], 'recurrence.': [1595], 'combine': [1599], 'produce': [1601, 3206], 'strategy': [1604], 'shown': [1605, 2003, 2385, 3635], '5.': [1608, 1623], 'Most': [1609], 'under': [1614, 2877], 'anesthesia': [1616], 'closure': [1619], 'defect.': [1621], 'Recommended': [1624], '(Breslow)': [1631], 'Safety': [1632], '0.5': [1636], '≤2': [1638], '>2': [1642], 'dealing': [1647], 'micrographic': [1655], 'using': [1657, 2255, 2406, 2674], 'permanent': [1658], 'sections': [1659], 'allow': [1661], 'narrower': [1663], 'safety.': [1666], 'Radiation': [1667, 2503, 2505], 'therapy': [1668, 1947, 1997, 2016, 2192, 2232, 2294, 2418, 2506, 2589, 2612, 2616, 2777, 2782, 2790, 2863, 2898, 3761], 'possible': [1671, 3603], 'facial': [1676], 'maligna.': [1678], 'than1': [1690], 'If': [1692, 1821, 1843, 1928, 3291], 'signs': [1695, 3033, 3243], 'present': [1697], '(Clark': [1698], 'IV/V,': [1700], 'sentinel': [1705, 1737, 1760, 1830, 2187], 'considered': [1711], 'thinner': [1713], 'biopsies': [1718], 'centers': [1723], 'experienced': [1724], 'both': [1726, 2282], 'nuclear': [1728], 'medicine': [1729], 'operative': [1731], 'aspects': [1732], 'procedure.': [1735], 'procedure': [1745, 1863, 2892], 'therapeutic': [1749, 2871], 'proven': [1753], 'positive': [1754, 2397], 'effect': [1755, 2655, 2944], 'overall': [1757, 1866, 2149, 2404, 3065, 3217], 'survival.': [1758, 1867, 2150, 2345, 3066, 3218], 'increases': [1764], 'length': [1766], 'recurrence-free': [1768, 2012, 2128, 2286, 2344, 2393], 'help': [1780], 'decide': [1781], 'adjuvant': [1783, 2015, 2190, 2231, 2417, 3626, 3760], 'systemic': [1784, 2916], 'therapy.': [1785, 2685, 2697, 2830, 2907, 3290], 'head': [1794], 'neck': [1796, 1808, 1922], 'region,': [1797], 'accomplished': [1804], 'excision,': [1813], 'depending': [1814], 'indication': [1825, 2827], 'node,': [1832], 'further': [1834], 'indicated': [1838, 2509], 'micrometastasis': [1845], 'identified,': [1847], 'typically': [1854], 'performed.': [1855, 1885], 'There': [1856, 2211], 'convincing': [1859], 'that': [1861, 2317, 2850, 2889, 3590], 'improves': [1864, 3063], 'Palliative': [1868, 2908, 3019], 'transit': [1878], 'metastases,': [1879, 1898, 1911, 2769], 'complete': [1880, 2656], 'single': [1888, 2749, 2774, 3147], 'limb': [1889], 'transmit': [1897], 'hyper-thermic': [1899], 'perfusion': [1900, 2600], 'cytostatic': [1902, 3051], 'agents': [1903, 3008, 3052, 3201], '(or': [1917], 'modified': [1919], 'selective': [1921], 'dissection)': [1923], 'curative': [1926], 'attempt.': [1927], 'tumor-free': [1930], 'obtained': [1934, 3304], 'if': [1936, 1954, 2645, 2650], 'operation': [1938], 'appropriate': [1941, 3629], 'patient,': [1944], 'radiation': [1946, 2537, 2611, 2684, 2776, 2781, 2829, 2862, 2897], 'recommended.': [1949, 2575, 2591, 2733, 2779], 'diseases': [1953], 'potentially': [1958], 'completely': [1959], 'resectable': [1960], '(R0': [1961], 'intention),': [1962], 'approach': [1965], 'undertaken.': [1968], 'Further': [1969], 'recommendations': [1970, 3631], 'setting': [1973], 'unclear': [1975], 'decided': [1979], 'individual': [1982, 2727, 2852], 'basis': [1983], 'multidisciplinary': [1986], 'team.': [1987], 'Adjuvant': [1988], 'Interferon-': [1990], 'substance': [1994], 'ad-juvant': [1996], 'prospective': [2005, 2094, 2279, 2332, 2373, 2884], 'randomized': [2006, 2095, 2253, 2280, 2333, 2374], 'studies': [2007, 2096, 2105, 2120, 2254, 2281, 2375, 2886, 3675, 3765], 'significantly': [2009, 3062], 'improve': [2010, 2845, 3056], 'interval.': [2013], 'IFN-α': [2018, 2107, 2160, 2191, 2259, 2276, 2337, 2366, 2479], 'offered': [2021, 2159, 2194], 'metastasis,': [2030, 2092], 'long': [2032, 2171], 'contraindications.': [2037, 2176], 'available': [2040, 2069, 2273, 3013], 'substances': [2041], 'IFN-α-2a': [2042], 'IFN-α-2b': [2044], 'differ': [2045], 'molecular': [2048], 'structure': [2049], 'amino': [2053], 'acids': [2054], 'identical': [2057], 'regards': [2059], 'receptor': [2061], 'binding,': [2062], 'efficacy,': [2063], 'side': [2065], 'effects.': [2066], 'Both': [2067, 3067], 'pegylated': [2071, 2336], 'prolonged': [2075, 2148], 'half-life,': [2076], 'making': [2077], 'weekly': [2078, 2113, 2166, 3168], 'administration': [2079, 3079], 'possible.': [2080], '≥1.50': [2087], 'carried': [2099], 'out': [2100], 'low-dose': [2102], 'IFN-α.': [2103, 2422], '3': [2108, 2111, 2161, 2164, 2430, 2493, 3150, 3154, 3166, 3399, 3424, 3462, 3613, 3693, 3699], 'million': [2109, 2162, 2431, 2450, 2465, 3163, 3172], 'IU': [2110, 2163, 2432], 'times': [2112, 2165], '6–18': [2115], 'months,': [2116, 2140, 2169], 'was': [2122, 2142, 3777], 'significant': [2124, 2341, 2387], 'prolongation': [2125], 'time.': [2129, 2763], 'largest': [2132], 'study': [2133, 2334], 'were': [2136], 'treated': [2137, 2609], '18': [2139, 2168], 'trend': [2145, 2398], 'group': [2156], 'Based': [2177], 'current': [2180, 3774], 'AJCC/UICC': [2181], 'consideration': [2184, 2224], 'status,': [2189], 'above': [2199], '(≥': [2202], '2.0': [2203], 'ulceration).': [2210, 2249], 'certain': [2214], 'data': [2215], 'proving': [2216], 'efficacy': [2217], 'lower': [2220], 'group,': [2222], 'so': [2223, 2849, 3549], 'given': [2227, 2834, 3253], 'offering': [2230], '(≥2.0': [2238], '≥4.0': [2244], 'variety': [2251, 2986], 'varying': [2256], 'dosages': [2257], 'clearest': [2270], 'results': [2271, 2371, 2880], 'high-dose': [2275, 2312], '-2b.': [2277], 'Two': [2278, 2382], 'show': [2283, 2888], 'improved': [2285, 2904], 'survival': [2287, 2408, 2811], 'control': [2291, 2528, 2902, 3241], 'patients.': [2292], 'standard': [2299], 'USA': [2302], 'Canada;': [2304], 'toxicity': [2310, 3261], 'INF-α': [2313], 'fact': [2316], 'subgroup': [2320], 'benefit,': [2323], 'interferon': [2325], 'regimens': [2326, 2988, 3221, 3249], '-2b': [2338, 2367, 2480], 'showed': [2339], 'increase': [2342], 'Patients': [2346, 2965], 'micrometastases': [2348], 'profit': [2349], 'most;': [2351], 'they': [2352, 2646], 'time': [2357, 2812, 3535], 'free': [2358], 'Low-dose': [2362], 'IFN-α-': [2363], '2a': [2364], 'achieved': [2369], 'conflicting': [2370], 'meta-analyses': [2383], 'improvement': [2388, 2402, 2691, 2808, 3030], '7%': [2390], 'survival,': [2394, 2405, 2848], '3%': [2401], '5-year': [2407], 'statistics': [2409], '(Table': [2410], '6).': [2411], '6.': [2413], 'Dosage': [2414], 'schedules': [2415], 'Schedule': [2423], 'Dose': [2424, 3092, 3327], 'Frequency': [2425], 'Duration': [2426], 'Indication': [2427], 'Low': [2428], 'dose': [2429, 2447, 2579, 2630, 2670, 2722, 2775, 3148], 's.c.': [2433, 3165], 'Days': [2434, 2468], '1,3': [2435, 2469], '&': [2436, 2470], '5': [2437, 2471, 2499, 3101, 3125, 3142, 3183, 3374, 3520, 3622], 'every': [2438, 2457, 2472, 2486, 2497, 3103, 3115, 3127, 3149, 3157, 3177, 3191, 3338, 3354, 3387, 3410, 3439, 3461, 3491, 3766], 'week': [2439, 2458, 2473, 2487, 2498, 3143], '18–24': [2440], 'months': [2441, 2475, 2815], 'II': [2443], '–': [2444], 'III': [2445, 2462, 2477, 2491, 2502, 3707], 'High': [2446], 'Initiation': [2448, 2481], '20': [2449], 'IU/m2': [2451, 2466, 3164], 'iv.': [2452], 'infusion': [2454, 3180], 'Day': [2455, 2484, 2495], '1–5': [2456, 3347, 3353, 3386, 3396, 3658, 3667], '4': [2459, 2814, 3128, 3355, 3365, 3492, 3617], 'weeks': [2460, 2489, 3105, 3117, 3129, 3151, 3356, 3389, 3412, 3441, 3493], 'Maintenance': [2463, 2492], '10': [2464, 2817, 2836, 3557], 's.c': [2467], '11': [2474], 'Pegylated': [2478], '6': [2482, 3171, 3682, 3695, 3700, 3703], 'μg/kg/week': [2483, 2494], '8': [2488, 2753, 3138, 3178, 3421, 3430, 3438, 3481, 3490], 'cases': [2518, 2735, 2853, 3234], 'impossible': [2523], 'reasonable.': [2526], 'Local': [2527, 2900], 'somewhat': [2533], 'less': [2534, 2784], 'satisfactory': [2535], 'therapy,': [2538, 3627], 'still': [2540, 2876], 'acceptable.': [2541], 'macroscopic': [2544], 'present,': [2547, 2571, 3295], 'irradiated': [2551, 2644], '3cm': [2554], '70': [2557], 'Gy,': [2558], 'fractionated': [2559], 'Gy': [2562, 2573, 2633, 2664, 2673, 2725, 2731, 2832], '5×': [2563], 'weekly.': [2564], 'microscopic': [2566], 'residual': [2567], '(R1)': [2569], '60': [2572], 'To': [2576], 'optimize': [2577], 'spare': [2584], 'normal': [2585], 'tissue,': [2586], 'electron': [2587, 2618], 'beam': [2588, 2615], 'inoperable': [2596, 2648, 2921, 2923], 'extremity': [2599], 'come': [2603], 'question': [2605], 'alone.': [2613, 2899], 'Electron': [2614], 'energies': [2619], '6–8': [2621], 'MeV': [2622], 'employed.': [2624, 2636], 'Using': [2625, 3227], 'conventional': [2626, 2675], 'fractionation,': [2627], 'total': [2629, 2669, 2721, 2761, 3551], '50–60': [2632], 'failed': [2653], '(R1': [2658], 'resection).': [2659], 'Single': [2660], 'doses': [2661, 2728, 2750, 2842], '1.8–2.0': [2663], '50–54': [2672], 'fractionation.': [2676], 'Bone': [2677], 'effectively': [2681, 3240], 'palliated': [2682], 'response': [2687, 3058], 'rate': [2688, 3094, 3329], '67–85%;': [2690], 'noted': [2694], 'during': [2695, 3533], 'indications': [2700, 2914], 'pain,': [2702], 'loss': [2703], 'structural': [2705, 2745], 'stability': [2706], '(fracture': [2707], 'risk),': [2708], 'compression': [2710], 'spinal': [2713], 'canal': [2714], 'neurological': [2718], 'symptoms.': [2719, 3035, 3245], '35–36': [2724], '2.5–3.0': [2730], 'limited': [2738, 2957, 2967], 'life': [2739, 3278], 'expectancy': [2740], 'threat': [2743], 'stability,': [2746], 'considerably': [2747], 'higher': [2748, 3207], 'Gy)': [2754], 'shorten': [2759], 'solitary': [2767], 'brain': [2768, 2797, 2820, 3000], 'stereotactic': [2773, 2793], 'toxic.': [2785], 'combination': [2787, 2860, 3049, 3248], '(operation': [2791], 'radiation)': [2794], 'whole': [2796], 'irradiation': [2798], 'effective': [2801, 2895, 3288], 'marked': [2807], 'mean': [2810], '(from': [2813], 'months).': [2818, 3650], 'Multiple': [2819], 'fractions': [2837], 'over': [2838], 'weeks.': [2840, 3193], 'Higher': [2841], 'median': [2847], 'enhancement': [2855], 'hyperthermia': [2865], '(thermoradiotherapy)': [2866], 'reasonable': [2870], 'option,': [2872], 'study.': [2878], 'retrospective': [2882], 'clinical': [2885], 'combined': [2891, 2906, 3202, 3220], 'Chemotherapy': [2909], 'hemoimmunotherapy': [2911], 'main': [2913], 'chemotherapy': [2917, 3196, 3200], 'chemoimmunotherapy': [2919, 3321], 'recurrences,': [2922], '(Stage': [2929], 'IV).': [2930], 'Since': [2931], 'palliative,': [2936], 'careful': [2937], 'attention': [2938, 3265], 'paid': [2941, 3268], 'quality': [2946, 3276], 'life.': [2948], 'one': [2952, 3113], 'distinguish': [2954], 'disease': [2958, 2961, 2968, 2994, 3598, 3620], 'patterns': [2962], '(metastases': [2969, 2995], 'skin,': [2972], 'soft': [2973], 'tissues,': [2974], 'nodes,': [2976], 'lungs)': [2978], 'respond': [2979], 'better': [2980, 3236], 'survive': [2982], 'longer': [2983], 'do': [2990], 'liver,': [2998], 'skeleton,': [2999], 'generalized': [3002], 'visceral': [3003], 'metastases).': [3004], 'comparable': [3010], 'effectiveness': [3011], 'monoche-motherapy': [3015], 'advanced': [3017, 3088, 3323], 'monochemotherapy': [3020], 'achieve': [3022], 'tumor-related': [3032], 'recommended': [3038], 'monotherapy': [3040, 3211], '7.': [3047, 3085], 'cytokines': [3054, 3204], 'rate.': [3059], 'Unfortunately': [3060], 'none': [3061], 'objective': [3069], 'subjective': [3071], 'tolerability': [3072], 'monochemo-therapy': [3074], 'worsened': [3076], 'concomitant': [3078], 'IFN': [3081], 'IL-2.': [3083], 'Monotherapy': [3086], 'Medication': [3091], 'Response': [3093, 3328], 'Dacarbazine': [3095], '250': [3096, 3392], 'mg/m2': [3097, 3109, 3121, 3133, 3155, 3333, 3344, 3350, 3369, 3377, 3383, 3393, 3400, 3406, 3416, 3425, 3433, 3457, 3472, 3476, 3485], 'i.v.': [3098, 3110, 3134, 3156, 3181, 3334, 3351, 3361, 3370, 3384, 3394, 3401, 3407, 3417, 3426, 3434, 3445, 3458, 3477, 3486], 'daily': [3099, 3111, 3123], 'days': [3102, 3126, 3136, 3184, 3346, 3352, 3362, 3371, 3385, 3395, 3418, 3427, 3435, 3478, 3487], '3–4': [3104, 3116, 3411, 3440], '12.1–17.6%': [3107], '800–1200': [3108], 'day': [3114, 3159, 3335, 3379, 3402, 3408, 3446, 3459], '5.3–23%': [3118], 'Temozolomide': [3119], '150–200': [3120], 'p.o.': [3122, 3345, 3378], '13.5–21%': [3130], 'Fotemustine': [3131], '100': [3132, 3405], '1,': [3137, 3447], '15;': [3140], 'pause,': [3144], 'repeat': [3146], '7.4–24.2%': [3152], 'Vindesine': [3153, 3398, 3423], '14': [3158, 3187], '12–26%': [3160], 'Interferon-α': [3161], '9–18': [3162], '×': [3167], '13–25%': [3169], 'Interleukin-2': [3170], 'IU/kg': [3173], '15': [3175, 3359], 'min.': [3176], 'hours': [3179], '(total': [3185], 'doses).': [3188], '16–21.6%': [3189], 'Repeat': [3190], 'Similarly,': [3194], 'multiple-drug': [3195], 'regimen': [3197], '(polychemotherapy)': [3198], '(polychemoimmunotherapy)': [3205], 'remission': [3208], 'rates': [3209], 'fail': [3213], 'prolong': [3215], 'monotherapy.': [3226], 'polychemotherapy': [3228], 'polychemoimmu-notherapy': [3230], 'offer': [3235], 'palliation': [3237], 'tumor-associated': [3242], 'established': [3247], '8.': [3256, 3318], 'Because': [3257], 'potential': [3260], 'polychemotherapy,': [3263], 'particular': [3264], 'must': [3266], 'supportive': [3270], 'care': [3271], 'maximize': [3273], "patient's": [3275], 'while': [3279], 'receiving': [3280, 3759], 'treatment.': [3282, 3517], 'Regimens': [3283], 'containing': [3284], 'DTIC': [3285, 3348, 3381, 3391, 3414], 'require': [3286], 'highly': [3287], 'anti-emetic': [3289], 'bony': [3292], 'bisphosphonates': [3296], 'employed;': [3299], 'dental': [3300], 'consultation': [3301], 'regarding': [3305], 'hygiene': [3307], 'measures': [3308], 'reduce': [3310, 3451, 3469], 'biphosphonate-related': [3314], 'jaw': [3315], 'necrosis.': [3316], 'Polychemotherapy': [3319], 'Regimen': [3326], 'BHD': [3330], 'BCNU': [3331], '150': [3332, 3349], 'cycle;': [3340], '12.7–30.4%': [3341], 'Hydroxyurea': [3342], '1500': [3343], 'BOLD': [3357], 'Bleomycin': [3358], 'mg': [3360], '+': [3364, 3373, 3420, 3429, 3437, 3495, 3688], '22–40%': [3366], 'Vincristine': [3367], 'CCNU': [3375], '80': [3376], '200': [3382], '4–6': [3388], 'DVP': [3390, 3413], '31.4–45%': [3397], 'Cisplatin': [3404, 3431], '450': [3415], '24%': [3422], '50': [3432], 'CarboTax': [3442], 'Carboplatin': [3443], 'AUC6': [3444], 'four': [3449, 3467], 'cycles': [3450, 3468], 'AUC4': [3453], '12.1%': [3454], 'Paclitaxel': [3455], '225': [3456], 'weeks,': [3463], '(second': [3464], 'line)': [3465], '175': [3471], 'GemTreo': [3473], 'Gemcitabine': [3474], '1000': [3475], '33.3%': [3482], 'Treosulfan': [3483], '3500': [3484], '(PR': [3494], 'SD,': [3496], 'uveal': [3497], 'melanoma)': [3498], 'Follow-up': [3499, 3580], 'frequency': [3501], 'extent': [3503], 'follow-up': [3505, 3552, 3633, 3644], 'examinations': [3506], 'depends': [3507], 'initial': [3510], 'parameters,': [3512], 'just': [3513], 'important,': [3526], 'occur': [3532], 'period.': [3536], 'On': [3537], 'hand,': [3540], 'late': [3547], 'period': [3553], 'extend': [3555], 'years.': [3558], 'Finally,': [3559], 'who': [3561], 'had': [3563], 'adding': [3574], 'importance': [3576], 'regular': [3578], 're-evaluation.': [3579], 'goals:': [3587], 'Confirming': [3589], 'recurred': [3595], 'identifying': [3597], 'Looking': [3606], 'Offering': [3614], 'psychosocial': [3615], 'support': [3616], 'Documenting': [3618], 'Administering': [3623], 'monitoring': [3625], 'Current': [3630], '9.': [3638, 3640], 'Recommendations': [3641], '(intervals': [3648], 'Physical': [3655, 3659], 'examination': [3656, 3660], 'Years': [3657, 3661, 3666, 3672, 3676], '6–10': [3662], 'Serum': [3668], 'levels': [3671], '1–5**': [3673], 'Imaging': [3674], '1–5***': [3677], 'I,': [3678], '12': [3683], 'II,': [3689], '>': [3690], '6–12': [3694, 3767], '3–6': [3696, 3701, 3702], 'None****': [3697], 'III*': [3698], 'Individual': [3705], '*Stage': [3706], '(>4': [3721], 'ulceration)': [3726], 'followed': [3729], 'III,': [3732, 3932], 'since': [3733], 'prognosis': [3735], 'similar.': [3737], '**S100': [3738], 'parameter': [3743], 'suited': [3744], 'detecting': [3746], 'recurrences.': [3747], '***Abdominal': [3748], 'chest': [3751], 'x-ray,': [3752], 'CAT,': [3754], 'PET.': [3757], '****Patients': [3758], 'imaging': [3764], 'months.': [3768], 'Consensus-building': [3769], 'Process': [3770], 'Participants': [3772], 'guideline': [3776, 3979], 'written': [3778], 'July': [3780], 'September': [3782], '2007': [3783], 'interdisciplinary': [3785], 'cooperation': [3786], 'Cancer': [3790], 'Society': [3791], 'Dermatologic': [3795], 'Society,': [3796], 'full-length': [3800], 'guidelines': [3801, 4005], 'published': [3802, 4008], '"Interdisziplinären': [3804], 'Leitlinien': [3805, 4151], 'zur': [3806, 4152], 'Diagnostik': [3807, 4153], 'und': [3808, 3910, 3924, 3961, 4154], 'Behandlung': [3809, 4155], 'von': [3810, 4156], 'Hauttumoren"': [3811], '(C.': [3812], 'ed.),': [3814], 'Kapitel': [3815], '"Deutsche': [3816], 'Leitlinie:': [3817, 4143], 'Malignes': [3818, 4144], 'Melanoma"': [3819], 'authors': [3822, 4101], 'Tübingen;': [3825, 3881], 'Kiel,': [3828], 'München,': [3831], 'Mannheim;': [3834, 3885], 'München;': [3837, 3896], 'Rolf-': [3838], 'Dieter': [3839], 'Leipzig,': [3841], 'Basel,': [3844], 'Leipzig;': [3847, 3912, 3927], 'Berlin;': [3850, 3937], 'Zürich;': [3853, 3943], 'Günter': [3854], 'Dresden;': [3856, 3947], 'Homburg;': [3859, 3951], 'Erlangen;': [3862, 3955, 3964], 'Regensburg;': [3865], 'Frankfurt.': [3868], 'Guideline': [3869], 'coordinator:': [3870], 'C.': [3873], 'Universitäts-Hautklinik': [3875, 3880, 3884, 3893, 3946, 3950, 3954, 3967, 3971], 'Tübingen.': [3876], 'Authors:': [3877], 'Hautklinik': [3888], 'München': [3889], 'Schwabing;': [3890], 'LMU': [3895], 'Fachbereich': [3899], 'Dermatologie,': [3900], 'Medizinisches': [3901], 'Zentrum': [3902], 'Bonn': [3903], 'Friedensplatz;': [3904], 'Kort-mann,': [3906], 'Universitäts-Klinik': [3907, 3920, 3931, 3958], 'für': [3908, 3921, 3959], 'Strahlentherapie': [3909], 'Radioonkologie': [3911], 'Allgemein-Chirurgie,': [3915], 'Universitäts-Spital': [3916, 3942], 'Basel;': [3917], 'Mund-,': [3922], 'Kiefer-': [3923], 'Plastische': [3925], 'Gesichtschirurgie': [3926], 'Medizinische': [3930], 'Campus': [3933], 'Benjamin': [3934], 'Franklin,': [3935], 'Charité': [3936], 'Dermatologische': [3940], 'Klinik,': [3941], 'Hämatologie': [3960], 'Internisti-sche': [3962], 'Onkologie': [3963], 'Frankfurt;': [3968], 'Kiel.': [3972], 'Next': [3973], 'update': [3974], 'planned:': [3975], 'Spring': [3976], '2010.': [3977], 'coordinator': [3980], 'queried': [3982], 'yearly': [3983], 'ISTO': [3985], '(Information': [3986], 'Center': [3987], 'Standards': [3989], 'Oncology)': [3991], 'required': [3993], 'updates.': [3994], 'case': [3996], 'needed,': [3999], 'updated': [4001], 'http://www.krebsgesellschaft.de,': [4010], 'http://www.ado-homepage.de': [4011], 'http://www.awmf.org.': [4013], 'Conflict': [4014], 'interest': [4016], 'Hauschild': [4018, 4113], 'declares': [4019], 'conflict': [4022, 4106], 'interest:': [4024], 'past': [4027], 'he': [4030], 'acted': [4032], 'consultant': [4035], 'lecture': [4039], 'fees': [4040], 'from:': [4041], 'MEDA': [4043], 'Pharma': [4044, 4094], '(Germany)': [4045, 4077, 4081, 4084, 4095], 'Abraxis': [4047], 'Oncology': [4048], '(USA)': [4049, 4070, 4087, 4098], 'BayerSchering': [4051], '(Germany/USA)': [4052], 'BMS': [4054], '(USA,': [4055, 4073, 4090], 'Europe)': [4056, 4074], 'Celgene': [4058], '(Europe)': [4059], 'essex': [4061], 'pharma/Schering-Plough': [4062], '(Germany,': [4063], 'USA)': [4064], 'Galderma': [4066], 'Deutschland': [4067], 'Genta': [4069], 'GSK': [4072], 'Hermal': [4076], 'La': [4079], 'Roche-Posay': [4080], 'Merck': [4083], 'Onyx': [4086], 'Pfizer': [4089], 'Germany)': [4091], 'Roche': [4093], 'Synta': [4097], 'remaining': [4100], 'declared': [4104], 'interests.': [4108], 'References': [4109], 'Garbe': [4111, 4148], 'C,': [4112, 4124], 'A,': [4114, 4138], 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